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Mice, Inbred MRL lpr

"Mice, Inbred MRL lpr" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.


This graph shows the total number of publications written about "Mice, Inbred MRL lpr" by people in Harvard Catalyst Profiles by year, and whether "Mice, Inbred MRL lpr" was a major or minor topic of these publication.
Bar chart showing 118 publications over 27 distinct years, with a maximum of 9 publications in 1998 and 2002
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.