Lac Repressors

"Lac Repressors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Bacterial repressor proteins that bind to the LAC OPERON and thereby prevent the synthesis of proteins involved in catabolism of LACTOSE. When lactose levels are high lac repressors undergo an allosteric change that causes their release from the DNA and the resumption of lac operon transcription.

Descriptor ID

D056968

MeSH Number(s)

D12.776.097.521

D12.776.260.703.600

D12.776.930.700.781

Concept/Terms

Lac Repressors

Below are MeSH descriptors whose meaning is more general than "Lac Repressors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Bacterial Proteins [D12.776.097]
Lac Repressors [D12.776.097.521]
DNA-Binding Proteins [D12.776.260]
Repressor Proteins [D12.776.260.703]
Lac Repressors [D12.776.260.703.600]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.700]
Lac Repressors [D12.776.930.700.781]

Below are MeSH descriptors whose meaning is related to "Lac Repressors".

Below are MeSH descriptors whose meaning is more specific than "Lac Repressors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lac Repressors" by people in Harvard Catalyst Profiles by year, and whether "Lac Repressors" was a major or minor topic of these publication.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2000	0	1	1
2001	0	1	1
2005	0	1	1
2012	0	1	1
2014	0	1	1
2015	1	1	2
2016	0	1	1
2019	0	1	1
2021	0	1	1

Below are the most recent publications written about "Lac Repressors" by people in Profiles.

Modular and Single-Cell Sensors of Bacterial Ser/Thr Kinase Activity. ACS Synth Biol. 2021 09 17; 10(9):2340-2350.

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Engineered signal-coupled inducible promoters: measuring the apparent RNA-polymerase resource budget. Nucleic Acids Res. 2020 09 25; 48(17):9995-10012.

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In Vitro Transcriptional Regulation via Nucleic-Acid-Based Transcription Factors. ACS Synth Biol. 2019 11 15; 8(11):2558-2565.

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Seeing red; the development of pON.mCherry, a broad-host range constitutive expression plasmid for Gram-negative bacteria. PLoS One. 2017; 12(3):e0173116.

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Creating Single-Copy Genetic Circuits. Mol Cell. 2016 07 21; 63(2):329-336.

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Engineering an allosteric transcription factor to respond to new ligands. Nat Methods. 2016 Feb; 13(2):177-83.

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DksA involvement in transcription fidelity buffers stochastic epigenetic change. Nucleic Acids Res. 2015 Dec 02; 43(21):10190-9.

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Removal of 8-oxo-GTP by MutT hydrolase is not a major contributor to transcriptional fidelity. Nucleic Acids Res. 2014 Oct 29; 42(19):12015-26.

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Inducible genetic system for the axolotl. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13662-7.

View in: PubMed
Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules. EMBO J. 2011 Aug 09; 30(19):3940-6.

View in: PubMed

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