Receptors, Tumor Necrosis Factor, Member 14
"Receptors, Tumor Necrosis Factor, Member 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
MeSH Number(s)
D12.776.543.750.705.852.760.500
D12.776.543.750.925.850
Concept/Terms
Receptors, Tumor Necrosis Factor, Member 14- Receptors, Tumor Necrosis Factor, Member 14
- HveA Protein
- Tumor Necrosis Factor Receptor Superfamily, Member 14
- Tumor Necrosis Factor Receptor Subfamily, Member 14
- Herpesvirus Entry Mediator
- Entry Mediator, Herpesvirus
- HVEM Protein
Below are MeSH descriptors whose meaning is more general than "Receptors, Tumor Necrosis Factor, Member 14".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.705.852.760.500]
- Receptors, Virus [D12.776.543.750.925]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.925.850]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Tumor Necrosis Factor, Member 14".
This graph shows the total number of publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Tumor Necrosis Factor, Member 14" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in Profiles.
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Herpesvirus entry mediator on radiation-resistant cell lineages promotes ocular herpes simplex virus 1 pathogenesis in an entry-independent manner. mBio. 2015 Oct 20; 6(5):e01532-15.
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Herpes virus entry mediator in human corneal epithelial cells modulates the production of inflammatory cytokines in response to HSV type 1 challenge. Ophthalmic Res. 2015; 54(3):128-34.
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Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV. Pediatr Res. 2014 Dec; 76(6):528-34.
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Significant involvement of herpesvirus entry mediator in human esophageal squamous cell carcinoma. Cancer. 2014 Mar 15; 120(6):808-17.
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Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci. J Hepatol. 2012 Aug; 57(2):366-75.
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BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction. J Leukoc Biol. 2012 Sep; 92(3):593-603.
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Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet. 2012 Mar 09; 90(3):524-32.
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Soluble B and T lymphocyte attenuator possesses antitumor effects and facilitates heat shock protein 70 vaccine-triggered antitumor immunity against a murine TC-1 cervical cancer model in vivo. J Immunol. 2009 Dec 15; 183(12):7842-50.
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Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1. Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42):17916-20.
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The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation. Immunol Rev. 2009 May; 229(1):244-58.