Host Cell Factor C1

"Host Cell Factor C1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cellular transcriptional coactivator that was originally identified by its requirement for the stable assembly IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. It is a nuclear protein that is a transcriptional coactivator for a number of transcription factors including VP16 PROTEIN; GA-BINDING PROTEIN; EARLY GROWTH RESPONSE PROTEIN 2; and E2F4 TRANSCRIPTION FACTOR. It also interacts with and stabilizes HERPES SIMPLEX VIRUS PROTEIN VMW65 and helps regulate GENETIC TRANSCRIPTION of IMMEDIATE-EARLY GENES in HERPES SIMPLEX VIRUS.

Descriptor ID

D051863

MeSH Number(s)

D12.776.930.325

Concept/Terms

Host Cell Factor C1

Below are MeSH descriptors whose meaning is more general than "Host Cell Factor C1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Host Cell Factor C1 [D12.776.930.325]

Below are MeSH descriptors whose meaning is related to "Host Cell Factor C1".

Below are MeSH descriptors whose meaning is more specific than "Host Cell Factor C1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Host Cell Factor C1" by people in Harvard Catalyst Profiles by year, and whether "Host Cell Factor C1" was a major or minor topic of these publication.

Bar chart showing 18 publications over 12 distinct years, with a maximum of 2 publications in 1996 and 1999 and 2016 and 2017 and 2019 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1996	0	2	2
1998	0	1	1
1999	0	2	2
2002	0	1	1
2013	1	0	1
2015	1	0	1
2016	2	0	2
2017	1	1	2
2018	0	1	1
2019	1	1	2
2021	1	1	2

Below are the most recent publications written about "Host Cell Factor C1" by people in Profiles.

Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 01 10; 13(1):134.

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The dystonia gene THAP1 controls DNA double-strand break repair choice. Mol Cell. 2021 06 17; 81(12):2611-2624.e10.

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Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase. Proc Natl Acad Sci U S A. 2021 01 26; 118(4).

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HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP. Mol Cell. 2019 07 25; 75(2):357-371.e7.

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Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Cell. 2019 04 18; 177(3):722-736.e22.

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Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans. Genetics. 2018 12; 210(4):1329-1337.

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Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017 Nov 07; 21(6):1562-1573.

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Aspartate Glycosylation Triggers Isomerization to Isoaspartate. J Am Chem Soc. 2017 03 08; 139(9):3332-3335.

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How the glycosyltransferase OGT catalyzes amide bond cleavage. Nat Chem Biol. 2016 Nov; 12(11):899-901.

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The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells? Annu Rev Biochem. 2016 Jun 02; 85:631-57.

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