COUP Transcription Factor I

"COUP Transcription Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A COUP transcription factor that was originally identified as a homodimer that binds to a direct repeat regulatory element in the chicken albumin promoter. It is a transcription factor that plays an important role in EMBRYONIC DEVELOPMENT of the CENTRAL NERVOUS SYSTEM.

Descriptor ID

D051838

MeSH Number(s)

D12.776.260.698.209.039.249

D12.776.826.209.039.249

D12.776.930.669.209.039.249

Concept/Terms

COUP Transcription Factor I

Below are MeSH descriptors whose meaning is more general than "COUP Transcription Factor I".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Receptors, Cytoplasmic and Nuclear [D12.776.260.698]
Orphan Nuclear Receptors [D12.776.260.698.209]
COUP Transcription Factors [D12.776.260.698.209.039]
COUP Transcription Factor I [D12.776.260.698.209.039.249]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Orphan Nuclear Receptors [D12.776.826.209]
COUP Transcription Factors [D12.776.826.209.039]
COUP Transcription Factor I [D12.776.826.209.039.249]
Transcription Factors [D12.776.930]
Receptors, Cytoplasmic and Nuclear [D12.776.930.669]
Orphan Nuclear Receptors [D12.776.930.669.209]
COUP Transcription Factors [D12.776.930.669.209.039]
COUP Transcription Factor I [D12.776.930.669.209.039.249]

Below are MeSH descriptors whose meaning is related to "COUP Transcription Factor I".

Below are MeSH descriptors whose meaning is more specific than "COUP Transcription Factor I".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "COUP Transcription Factor I" by people in Harvard Catalyst Profiles by year, and whether "COUP Transcription Factor I" was a major or minor topic of these publication.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2009 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2009	2	0	2
2010	1	0	1
2011	1	0	1
2016	1	0	1
2020	2	0	2
2021	0	1	1

Below are the most recent publications written about "COUP Transcription Factor I" by people in Profiles.

Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 12 21; 118(51).

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Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation. Cell Rep. 2020 04 21; 31(3):107521.

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Phenotypic expansion of Bosch-Boonstra-Schaaf optic atrophy syndrome and further evidence for genotype-phenotype correlations. Am J Med Genet A. 2020 06; 182(6):1426-1437.

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The expanding clinical phenotype of Bosch-Boonstra-Schaaf optic atrophy syndrome: 20 new cases and possible genotype-phenotype correlations. Genet Med. 2016 11; 18(11):1143-1150.

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Genomic analysis identifies candidate pathogenic variants in 9 of 18 patients with unexplained West syndrome. Hum Genet. 2015 Jun; 134(6):649-58.

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A coregulatory network of NR2F1 and microRNA-140. PLoS One. 2013; 8(12):e83358.

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COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov; 138(21):4685-97.

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Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy. J Neurosci. 2011 Mar 23; 31(12):4650-62.

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Area-specific temporal control of corticospinal motor neuron differentiation by COUP-TFI. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3576-81.

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Immunohistochemistry of COUP-TFI: an adjuvant diagnostic tool for the identification of corticotroph microadenomas. Pituitary. 2010; 13(1):1-7.

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