Collagen Type XVIII

"Collagen Type XVIII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A non-fibrillar collagen found in BASEMENT MEMBRANE. The C-terminal end of the alpha1 chain of collagen type XVIII contains the ENDOSTATIN peptide, which can be released by proteolytic cleavage.

Descriptor ID

D043170

MeSH Number(s)

D12.776.860.300.250.400.537

Concept/Terms

Collagen Type XVIII

Procollagen Type XVIII

Collagen Type XVIII, alpha1 Subunit

Below are MeSH descriptors whose meaning is more general than "Collagen Type XVIII".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Collagen [D12.776.860.300.250]
Non-Fibrillar Collagens [D12.776.860.300.250.400]
Collagen Type XVIII [D12.776.860.300.250.400.537]

Below are MeSH descriptors whose meaning is related to "Collagen Type XVIII".

Below are MeSH descriptors whose meaning is more specific than "Collagen Type XVIII".

Collagen Type XVIII
Endostatins

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Collagen Type XVIII" by people in Harvard Catalyst Profiles by year, and whether "Collagen Type XVIII" was a major or minor topic of these publication.

Bar chart showing 41 publications over 17 distinct years, with a maximum of 7 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1997	0	1	1
1998	0	2	2
1999	0	2	2
2000	0	5	5
2001	0	3	3
2002	0	7	7
2003	3	1	4
2004	4	1	5
2005	1	1	2
2007	1	0	1
2008	0	1	1
2010	0	1	1
2013	3	0	3
2015	1	0	1
2020	0	1	1
2021	0	1	1

Below are the most recent publications written about "Collagen Type XVIII" by people in Profiles.

Whole exome sequencing revealed novel variants in consanguineous Pakistani families with intellectual disability. Genes Genomics. 2021 05; 43(5):503-512.

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Functional Impact of Human Genetic Variants of COL18A1/Endostatin on Pulmonary Endothelium. Am J Respir Cell Mol Biol. 2020 04; 62(4):524-534.

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Collagen XVIII in tissue homeostasis and dysregulation - Lessons learned from model organisms and human patients. Matrix Biol. 2017 01; 57-58:55-75.

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Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2015 Jan 15; 191(2):208-18.

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Basement membrane zone collagens XV and XVIII/proteoglycans mediate leukocyte influx in renal ischemia/reperfusion. PLoS One. 2014; 9(9):e106732.

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Serum endostatin levels are elevated in colorectal cancer and correlate with invasion and systemic inflammatory markers. Br J Cancer. 2014 Oct 14; 111(8):1605-13.

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Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3043-52.

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Collagen XVIII short isoform is critical for retinal vascularization, and overexpression of the Tsp-1 domain affects eye growth and cataract formation. Invest Ophthalmol Vis Sci. 2013 Nov 13; 54(12):7450-62.

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Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma. Clin Genet. 2013 Aug; 84(2):167-74.

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No evidence for locus heterogeneity in Knobloch syndrome. J Med Genet. 2013 Aug; 50(8):565-6.

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