Pralidoxime Compounds

"Pralidoxime Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.

Descriptor ID

D011220

MeSH Number(s)

D02.092.570.665.535

Concept/Terms

Pralidoxime Compounds

Below are MeSH descriptors whose meaning is more general than "Pralidoxime Compounds".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amines [D02.092]
Hydroxylamines [D02.092.570]
Oximes [D02.092.570.665]
Pralidoxime Compounds [D02.092.570.665.535]

Below are MeSH descriptors whose meaning is related to "Pralidoxime Compounds".

Below are MeSH descriptors whose meaning is more specific than "Pralidoxime Compounds".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pralidoxime Compounds" by people in Harvard Catalyst Profiles by year, and whether "Pralidoxime Compounds" was a major or minor topic of these publication.

Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 1995

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1995	2	2
2011	1	1
2012	1	1

Below are the most recent publications written about "Pralidoxime Compounds" by people in Profiles.

The First Use of Pralidoxime in a Child With Rivastigmine Poisoning. Pediatr Emerg Care. 2018 Oct; 34(10):e184-e186.

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An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action. J Biomol Screen. 2013 Jan; 18(1):108-15.

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Fecal-tagging CT colonography with structure-analysis electronic cleansing for detection of colorectal flat lesions. Eur J Radiol. 2012 Aug; 81(8):1712-6.

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Pralidoxime rescues both muscarinic and nicotinic systems. Anesth Analg. 2005 Sep; 101(3):926-927.

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Nerve agent toxicology. JEMS. 2003 Dec; 28(12):16; author reply 16.

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Organophosphorous compound poisoning : prolonged therapy in absence of intermediate neurotoxic syndrome. J Assoc Physicians India. 1995 Jan; 43(1):59-60.

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Use of C1300 neuroblastoma cells to evaluate the protective value of hexamethonium, trimethaphan, hemicholinium, and triethylcholine against diisopropyl phosphorofluoridate toxicity. J Pharm Sci. 1995 Jan; 84(1):65-70.

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Edrophonium and pralidoxime. Anesth Analg. 1989 Jun; 68(6):826-7.

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Combined atropine and 2-PAM Cl effects on tracking performance and visual, physiological, and psychological functions. Aviat Space Environ Med. 1988 Dec; 59(12):1125-32.

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Drug therapy. Anticholinergics. N Engl J Med. 1973 Jun 07; 288(23):1215-9.

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Anesth Analg
Pediatr Emerg Care
Aviat Space Environ Med
N Engl J Med
JEMS
J Pharm Sci
J Biomol Screen
J Assoc Physicians India
Eur J Radiol