Transcription Factor TFIIIB

"Transcription Factor TFIIIB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

One of several general transcription factors that are specific for RNA POLYMERASE III. TFIIIB recruits and positions pol III over the initiation site and remains stably bound to the DNA through multiple rounds of re-initiation by RNA POLYMERASE III.

Descriptor ID

D035361

MeSH Number(s)

D12.776.260.775.937.500

D12.776.930.930.937.500

Concept/Terms

Transcription Factor TFIIIB

TFIIIB-beta

TFIIIB-alpha

Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIIIB".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Transcription Factors, General [D12.776.260.775]
Transcription Factors, TFIII [D12.776.260.775.937]
Transcription Factor TFIIIB [D12.776.260.775.937.500]
Transcription Factors [D12.776.930]
Transcription Factors, General [D12.776.930.930]
Transcription Factors, TFIII [D12.776.930.930.937]
Transcription Factor TFIIIB [D12.776.930.930.937.500]

Below are MeSH descriptors whose meaning is related to "Transcription Factor TFIIIB".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIIIB".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factor TFIIIB" by people in Harvard Catalyst Profiles by year, and whether "Transcription Factor TFIIIB" was a major or minor topic of these publication.

Below are the most recent publications written about "Transcription Factor TFIIIB" by people in Profiles.

Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification. Genome Biol. 2015 May 22; 16:107.

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Involvement of RNA Polymerase III in Immune Responses. Mol Cell Biol. 2015 May; 35(10):1848-59.

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Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. PLoS Med. 2010 Jul 27; 7(7):e1000315.

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Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells. Nat Struct Mol Biol. 2010 May; 17(5):635-40.

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TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):14917-22.

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Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. Mol Cell. 2007 May 11; 26(3):367-79.

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TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs. Genes Dev. 2005 Apr 15; 19(8):955-64.

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The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment. Nucleic Acids Res. 2003 Apr 15; 31(8):2108-16.

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TATA-binding protein and associated factors in polymerase II and polymerase III transcription. Mol Cell Biol. 1993 Dec; 13(12):7953-60.

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Regional codon randomization: defining a TATA-binding protein surface required for RNA polymerase III transcription. Science. 1993 Oct 08; 262(5131):244-8.

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