5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
"5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of methionine by transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine. It requires a cobamide coenzyme. The enzyme can act on mono- or triglutamate derivatives. EC 2.1.1.13.
Concept/Terms
5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase- 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
- S-Methyltransferase, 5-Methyltetrahydrofolate-Homocysteine
- Methyltetrahydrofolate Homocysteine Methyltransferase
- Homocysteine Methyltransferase, Methyltetrahydrofolate
- Methyltransferase, Methyltetrahydrofolate Homocysteine
- Methionine Synthase
- Synthase, Methionine
- Methionine Synthetase
- Synthetase, Methionine
- Tetrahydropteroylglutamate Methyltransferase
- Methyltransferase, Tetrahydropteroylglutamate
Below are MeSH descriptors whose meaning is more general than "5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase".
Below are MeSH descriptors whose meaning is more specific than "5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase".
This graph shows the total number of publications written about "5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase" by people in Harvard Catalyst Profiles by year, and whether "5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2007 | 2 | 1 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase" by people in Profiles.
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Methionine synthase is essential for cancer cell proliferation in physiological folate environments. Nat Metab. 2021 11; 3(11):1500-1511.
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Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19970-19981.
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Analysis of fibroblasts from patients with cblC and cblG genetic defects of cobalamin metabolism reveals global dysregulation of alternative splicing. Hum Mol Genet. 2020 07 29; 29(12):1969-1985.
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Gene polymorphisms as risk factors for predicting the cardiovascular manifestations in Marfan syndrome. Role of folic acid metabolism enzyme gene polymorphisms in Marfan syndrome. Thromb Haemost. 2015 Oct; 114(4):748-56.
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Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman. Exp Biol Med (Maywood). 2014 Jun; 239(6):697-706.
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Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Mol Biol Cell. 2012 Aug; 23(15):2993-3007.
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Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway. Mol Biol Cell. 2012 Aug; 23(15):3008-24.
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Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia. Schizophr Bull. 2013 Mar; 39(2):330-8.
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Nutrients and genetic variation involved in one-carbon metabolism and Hodgkin lymphoma risk: a population-based case-control study. Am J Epidemiol. 2011 Oct 01; 174(7):816-27.
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Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol. 2011 Jan; 91(1):50-60.