Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Trimetrexate

"Trimetrexate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.


This graph shows the total number of publications written about "Trimetrexate" by people in Harvard Catalyst Profiles by year, and whether "Trimetrexate" was a major or minor topic of these publication.
Bar chart showing 4 publications over 3 distinct years, with a maximum of 2 publications in 1999
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.