Molsidomine

"Molsidomine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.

Descriptor ID

D008981

MeSH Number(s)

D03.383.129.462.580.693.450

D03.383.533.640.362

Concept/Terms

Molsidomin-ratiopharm

Below are MeSH descriptors whose meaning is more general than "Molsidomine".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Oxazoles [D03.383.129.462]
Oxadiazoles [D03.383.129.462.580]
Sydnones [D03.383.129.462.580.693]
Molsidomine [D03.383.129.462.580.693.450]
Oxazines [D03.383.533]
Morpholines [D03.383.533.640]
Molsidomine [D03.383.533.640.362]

Below are MeSH descriptors whose meaning is related to "Molsidomine".

Below are MeSH descriptors whose meaning is more specific than "Molsidomine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Molsidomine" by people in Harvard Catalyst Profiles by year, and whether "Molsidomine" was a major or minor topic of these publication.

Bar chart showing 18 publications over 11 distinct years, with a maximum of 3 publications in 2002 and 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	1	1	2
1999	0	2	2
2000	0	1	1
2001	1	1	2
2002	3	0	3
2003	1	0	1
2004	3	0	3
2005	0	1	1
2006	0	1	1
2018	0	1	1

Below are the most recent publications written about "Molsidomine" by people in Profiles.

Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability. Cell Death Dis. 2018 11 13; 9(11):1129.

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Development of a screening method to identify regulators of MICA shedding. Biochem Biophys Res Commun. 2015 Oct 02; 465(4):764-8.

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Protection against peroxynitrite by pseudoperoxidase from Leishmania major. Free Radic Biol Med. 2012 Nov 15; 53(10):1819-28.

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The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. J Exp Med. 2012 Apr 09; 209(4):837-54.

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Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells. Neurochem Int. 2010 May-Jun; 56(6-7):740-6.

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PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major. Curr Genet. 2009 Jun; 55(3):287-99.

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Modulation of stress-induced neurobehavioral changes and brain oxidative injury by nitric oxide (NO) mimetics in rats. Behav Brain Res. 2007 Nov 02; 183(2):226-30.

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Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status. J Agric Food Chem. 2006 Mar 08; 54(5):1638-45.

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Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr. Free Radic Biol Med. 2005 Jun 15; 38(12):1625-36.

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Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina. J Comp Neurol. 2005 Mar 14; 483(3):278-91.

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