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Hydroxymethylbilane Synthase

"Hydroxymethylbilane Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxymethylbilane preuroporphyrinogen (UROPORPHYRINOGENS) in several discrete steps. It is the third enzyme in the 8-enzyme biosynthetic pathway of HEME. In humans, deficiency in this enzyme encoded by HMBS (or PBGD) gene results in a form of neurological porphyria (PORPHYRIA, ACUTE INTERMITTENT). This enzyme was formerly listed as EC 4.3.1.8


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This graph shows the total number of publications written about "Hydroxymethylbilane Synthase" by people in Harvard Catalyst Profiles by year, and whether "Hydroxymethylbilane Synthase" was a major or minor topic of these publication.
Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 1995 and 2017 and 2022
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.