Harvard Catalyst Profiles

A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Below are MeSH descriptors whose meaning is more general than "Retinoblastoma".

Below are MeSH descriptors whose meaning is related to "Retinoblastoma".

Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma".