Transcription Factors, General
"Transcription Factors, General" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.
MeSH Number(s)
D12.776.260.775
D12.776.930.930
Below are MeSH descriptors whose meaning is more general than "Transcription Factors, General".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, General".
This graph shows the total number of publications written about "Transcription Factors, General" by people in Harvard Catalyst Profiles by year, and whether "Transcription Factors, General" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Transcription Factors, General" by people in Profiles.
-
Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species. Elife. 2021 09 13; 10.
-
Universal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae. Genome Biol. 2020 06 02; 21(1):132.
-
Requirements for RNA polymerase II preinitiation complex formation in vivo. Elife. 2019 01 25; 8.
-
ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans. PLoS Genet. 2017 02; 13(2):e1006611.
-
Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. J Med Chem. 2013 Dec 27; 56(24):10183-7.
-
Gene expression: transcription initiation unwrapped. Nature. 2012 Mar 14; 483(7389):286-7.
-
A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell. 2008 Jan 18; 29(1):92-101.
-
A mechanism for coordinating chromatin modification and preinitiation complex assembly. Mol Cell. 2006 Sep 15; 23(6):809-18.
-
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell. 2003 Dec; 12(6):1565-76.
-
Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage. Cell. 2003 Aug 08; 114(3):347-57.