Chondroitin Lyases

"Chondroitin Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.

Descriptor ID

D002808

MeSH Number(s)

D08.811.520.241.700.350.500

Concept/Terms

Chondroitin Lyases

Chondroitin Eliminase

Chondroitinase-AC II

Chondroitin B Lyase

Chondroitin Sulfate Lyase

Below are MeSH descriptors whose meaning is more general than "Chondroitin Lyases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Lyases [D08.811.520]
Carbon-Oxygen Lyases [D08.811.520.241]
Polysaccharide-Lyases [D08.811.520.241.700]
Chondroitinases and Chondroitin Lyases [D08.811.520.241.700.350]
Chondroitin Lyases [D08.811.520.241.700.350.500]

Below are MeSH descriptors whose meaning is related to "Chondroitin Lyases".

Below are MeSH descriptors whose meaning is more specific than "Chondroitin Lyases".

Chondroitin Lyases
Chondroitin ABC Lyase

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chondroitin Lyases" by people in Harvard Catalyst Profiles by year, and whether "Chondroitin Lyases" was a major or minor topic of these publication.

Bar chart showing 2 publications over 2 distinct years, with a maximum of 1 publications in 1996 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2017	1	0	1

Below are the most recent publications written about "Chondroitin Lyases" by people in Profiles.

Cloning and Expression of Recombinant Chondroitinase ACII and Its Comparison to the Arthrobacter aurescens Enzyme. Biotechnol J. 2017 Oct; 12(10).

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Age-related nanostructural and nanomechanical changes of individual human cartilage aggrecan monomers and their glycosaminoglycan side chains. J Struct Biol. 2013 Mar; 181(3):264-73.

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The biosynthesis and catabolism of galactosaminoglycans. Adv Pharmacol. 2006; 53:69-115.

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CS lyases: structure, activity, and applications in analysis and the treatment of diseases. Adv Pharmacol. 2006; 53:187-215.

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Preparation of the methyl ester of hyaluronan and its enzymatic degradation. Carbohydr Res. 2005 Oct 17; 340(14):2297-304.

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The structure of chondroitin B lyase complexed with glycosaminoglycan oligosaccharides unravels a calcium-dependent catalytic machinery. J Biol Chem. 2004 Jul 30; 279(31):32882-96.

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Chondroitin O-methyl ester: an unusual substrate for chondroitin AC lyase. Carbohydr Res. 2003 Sep 26; 338(20):2101-4.

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Recombinant expression, purification, and kinetic characterization of chondroitinase AC and chondroitinase B from Flavobacterium heparinum. Biochem Biophys Res Commun. 2001 Aug 17; 286(2):343-51.

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A chondroitin/dermatan sulfate form of CD44 is a receptor for collagen XIV (undulin). Exp Cell Res. 1996 Dec 15; 229(2):388-97.

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Cell surface glycosaminoglycans are not involved in the adherence of Helicobacter pylori to cultured Hs 198.St human gastric cells, Hs 746T human gastric adenocarcinoma cells, or HeLa cells. Glycoconj J. 1996 Oct; 13(5):873-7.

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