Harvard Catalyst Profiles

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Histamine H1 Antagonists

"Histamine H1 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.


publications
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This graph shows the total number of publications written about "Histamine H1 Antagonists" by people in Harvard Catalyst Profiles by year, and whether "Histamine H1 Antagonists" was a major or minor topic of these publication.
Bar chart showing 70 publications over 22 distinct years, with a maximum of 7 publications in 1999 and 2003 and 2004
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.