Therapeutic Equipoise

"Therapeutic Equipoise" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Expectation of real uncertainty on the part of the investigator regarding the comparative therapeutic merits of each arm in a trial.

Descriptor ID

D057212

MeSH Number(s)

K01.316.333.132.750.775

K01.316.366.700

Concept/Terms

Therapeutic Equipoise

Below are MeSH descriptors whose meaning is more general than "Therapeutic Equipoise".

Humanities [K]
Humanities [K01]
Ethics [K01.316]
Ethics, Professional [K01.316.333]
Ethics, Clinical [K01.316.333.132]
Ethics, Medical [K01.316.333.132.750]
Therapeutic Equipoise [K01.316.333.132.750.775]
Ethics, Research [K01.316.366]
Therapeutic Equipoise [K01.316.366.700]

Below are MeSH descriptors whose meaning is related to "Therapeutic Equipoise".

Below are MeSH descriptors whose meaning is more specific than "Therapeutic Equipoise".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Therapeutic Equipoise" by people in Harvard Catalyst Profiles by year, and whether "Therapeutic Equipoise" was a major or minor topic of these publication.

Bar chart showing 18 publications over 10 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	1	2
2011	0	1	1
2013	2	2	4
2014	0	1	1
2015	2	1	3
2016	0	1	1
2017	1	0	1
2019	0	1	1
2020	0	3	3
2022	0	1	1

Below are the most recent publications written about "Therapeutic Equipoise" by people in Profiles.

To tether or fuse? Significant equipoise remains in treatment recommendations for idiopathic scoliosis. Spine Deform. 2022 07; 10(4):763-773.

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Restarting Orthopaedic Care in a Pandemic: Ethical Framework and Case Examples. J Am Acad Orthop Surg. 2021 Jan 15; 29(2):e72-e78.

View in: PubMed
Cardiac safety research consortium "shock II" think tank report: Advancing practical approaches to generating evidence for the treatment of cardiogenic shock. Am Heart J. 2020 12; 230:93-97.

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Is it unethical to conduct placebo-controlled trials of faecal microbiota transplantation for recurrent Clostridioides difficile infection? Lancet Gastroenterol Hepatol. 2020 05; 5(5):432-433.

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Establishing Consensus on the Best Practice Guidelines for Use of Halo Gravity Traction for Pediatric Spinal Deformity. J Pediatr Orthop. 2020 Jan; 40(1):e42-e48.

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Is There Equipoise Regarding the Optimal Medical Treatment of Patients with Asymptomatic White Matter Hyperintensities? J Stroke Cerebrovasc Dis. 2019 Nov; 28(11):104371.

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Equipoise in Appropriate Initial Volume Resuscitation for Patients in Septic Shock With Heart Failure: Results of a Multicenter Clinician Survey. J Intensive Care Med. 2020 Nov; 35(11):1338-1345.

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Ethical Considerations in Ending Exploratory Brain-Computer Interface Research Studies in Locked-in Syndrome. Camb Q Healthc Ethics. 2018 10; 27(4):660-674.

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Research ethics for emerging trial designs: does equipoise need to adapt? BMJ. 2018 01 25; 360:k226.

View in: PubMed
The interaction between equipoise and logistics in clinical trials: A case study. Clin Trials. 2017 Jun; 14(3):314-318.

View in: PubMed

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