Receptors, Polymeric Immunoglobulin
"Receptors, Polymeric Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
MeSH Number(s)
D12.776.543.750.705.871.700
Concept/Terms
Receptors, Polymeric Immunoglobulin- Receptors, Polymeric Immunoglobulin
- Polymeric Immunoglobulin Receptors
- Immunoglobulin Receptors, Polymeric
- Receptor, Polyimmunoglobulin
- Receptor, Polymeric Ig
- Poly-Ig Receptor
- Poly Ig Receptor
- Receptor, Poly-Ig
- Polyimmunoglobulin Receptor
- Polymeric Immunoglobulin Receptor
- Immunoglobulin Receptor, Polymeric
- Receptor, Polymeric Immunoglobulin
- Polymeric Ig Receptor
- Ig Receptor, Polymeric
Below are MeSH descriptors whose meaning is more general than "Receptors, Polymeric Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Polymeric Immunoglobulin".
This graph shows the total number of publications written about "Receptors, Polymeric Immunoglobulin" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Polymeric Immunoglobulin" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, Polymeric Immunoglobulin" by people in Profiles.
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Identification of the Fc-alpha/mu receptor in Xenopus provides insight into the emergence of the poly-Ig receptor (pIgR) and mucosal Ig transport. Eur J Immunol. 2021 11; 51(11):2590-2606.
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Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules. Mol Biol Cell. 2013 Aug; 24(15):2398-405.
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Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J Exp Med. 2003 Jul 21; 198(2):223-33.
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Targeting mucosal sites by polymeric immunoglobulin receptor-directed peptides. J Exp Med. 2002 Aug 19; 196(4):551-5.