Arylalkylamine N-Acetyltransferase

"Arylalkylamine N-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An acetyltransferase with specificity towards the amine group of aromatic alkylamines (arylalkylamines) such as SEROTONIN. This enzyme is also referred to as serotonin acetylase despite the fact that serotonin acetylation can also occur through the action of broad specificity acetyltransferases such as ARYLAMINE N-ACETYLTRANSFERASE.

Descriptor ID

D047068

MeSH Number(s)

D08.811.913.050.294

Concept/Terms

Arylalkylamine N-Acetyltransferase

Below are MeSH descriptors whose meaning is more general than "Arylalkylamine N-Acetyltransferase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Acyltransferases [D08.811.913.050]
Arylalkylamine N-Acetyltransferase [D08.811.913.050.294]

Below are MeSH descriptors whose meaning is related to "Arylalkylamine N-Acetyltransferase".

Below are MeSH descriptors whose meaning is more specific than "Arylalkylamine N-Acetyltransferase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Arylalkylamine N-Acetyltransferase" by people in Harvard Catalyst Profiles by year, and whether "Arylalkylamine N-Acetyltransferase" was a major or minor topic of these publication.

Bar chart showing 10 publications over 6 distinct years, with a maximum of 4 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	3	4
2006	1	0	1
2007	1	0	1
2008	1	1	2
2017	1	0	1
2023	0	1	1

Below are the most recent publications written about "Arylalkylamine N-Acetyltransferase" by people in Profiles.

Evaluation of Rhodanine Indolinones as AANAT Inhibitors. ChemMedChem. 2024 01 02; 19(1):e202300567.

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Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. Int J Cancer. 2017 11 01; 141(9):1794-1802.

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Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway. J Biol Chem. 2016 08 12; 291(33):17178-96.

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Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine. Biochemistry. 2015 Apr 28; 54(16):2644-58.

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Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases. Biochemistry. 2014 Dec 16; 53(49):7777-93.

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Casein kinase 1d activity: a key element in the zebrafish circadian timing system. PLoS One. 2013; 8(1):e54189.

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Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis. Biochemistry. 2008 Sep 30; 47(39):10407-19.

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Novel functions for Period 3 and Exo-rhodopsin in rhythmic transcription and melatonin biosynthesis within the zebrafish pineal organ. Brain Res. 2008 Aug 05; 1223:11-24.

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De novo discovery of serotonin N-acetyltransferase inhibitors. J Med Chem. 2007 Nov 01; 50(22):5330-8.

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Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug. Bioorg Med Chem. 2007 Mar 01; 15(5):2147-55.

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