Receptors, Interleukin-5

"Receptors, Interleukin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface receptors that are specific for INTERLEUKIN-5. They are heterodimeric proteins consisting of the INTERLEUKIN-5 RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR COMMON BETA SUBUNIT. Signaling from interleukin-5 receptors can occur through interaction of their cytoplasmic domains with SYNTENINS.

Descriptor ID

D053649

MeSH Number(s)

D12.776.543.750.705.852.420.380

Concept/Terms

Receptors, Interleukin-5

Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-5".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-5 [D12.776.543.750.705.852.420.380]

Below are MeSH descriptors whose meaning is related to "Receptors, Interleukin-5".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-5".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Interleukin-5" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Interleukin-5" was a major or minor topic of these publication.

Bar chart showing 15 publications over 10 distinct years, with a maximum of 3 publications in 1997 and 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	2	2
1997	0	3	3
1998	0	1	1
1999	0	3	3
2000	0	1	1
2001	0	1	1
2005	0	1	1
2016	1	0	1
2019	0	1	1

Below are the most recent publications written about "Receptors, Interleukin-5" by people in Profiles.

Benralizumab for the Prevention of COPD Exacerbations. N Engl J Med. 2019 09 12; 381(11):1023-1034.

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GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation. Immunity. 2019 04 16; 50(4):796-811.

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Interleukin-5 Antagonists Usher in a New Generation of Asthma Therapy. Curr Allergy Asthma Rep. 2016 Nov; 16(11):80.

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Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders: evidence and unmet needs. Curr Opin Allergy Clin Immunol. 2016 Apr; 16(2):186-200.

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Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med. 2005 Jun 20; 201(12):1891-7.

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Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency. J Immunol. 2002 Mar 15; 168(6):3017-23.

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Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting protein. Science. 2001 Aug 10; 293(5532):1136-8.

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Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells. Immunology. 2001 Mar; 102(3):289-300.

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Specificity in cytokine signal transduction: lessons learned from the IL-3/IL-5/GM-CSF receptor family. Cytokine Growth Factor Rev. 2001 Mar; 12(1):19-25.

View in: PubMed
Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA. FEBS Lett. 2000 Jul 28; 478(1-2):100-4.

View in: PubMed

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