Genes, jun

"Genes, jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Retrovirus-associated DNA sequences (jun) originally isolated from the avian sarcoma virus 17 (ASV 17). The proto-oncogene jun (c-jun) codes for a nuclear protein which is involved in growth-related transcriptional control. Insertion of c-jun into ASV-17 or the constitutive expression of the c-jun protein produces tumorgenicity. The human c-jun gene is located at 1p31-32 on the short arm of chromosome 1.

Descriptor ID

D016758

MeSH Number(s)

G05.360.340.024.340.375.500.791.365

Concept/Terms

c-jun Proto-Oncogenes

v-jun Genes

Below are MeSH descriptors whose meaning is more general than "Genes, jun".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Oncogenes [G05.360.340.024.340.375.500]
Proto-Oncogenes [G05.360.340.024.340.375.500.791]
Genes, jun [G05.360.340.024.340.375.500.791.365]

Below are MeSH descriptors whose meaning is related to "Genes, jun".

Below are MeSH descriptors whose meaning is more specific than "Genes, jun".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, jun" by people in Harvard Catalyst Profiles by year, and whether "Genes, jun" was a major or minor topic of these publication.

Bar chart showing 34 publications over 14 distinct years, with a maximum of 7 publications in 1994

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	5	7
1995	2	4	6
1996	2	3	5
1998	0	1	1
1999	0	2	2
2000	0	1	1
2001	0	1	1
2002	0	2	2
2003	3	1	4
2008	0	1	1
2009	0	1	1
2011	0	1	1
2016	0	1	1
2017	0	1	1

Below are the most recent publications written about "Genes, jun" by people in Profiles.

Comparative Transcriptomics Highlights the Role of the Activator Protein 1 Transcription Factor in the Host Response to Ebolavirus. J Virol. 2017 12 01; 91(23).

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Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun. ACS Chem Biol. 2017 08 18; 12(8):2051-2061.

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eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature. 2016 08 04; 536(7614):96-9.

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Regulation of oxidative stress by methylation-controlled J protein controls macrophage responses to inflammatory insults. J Infect Dis. 2015 Jan 01; 211(1):135-45.

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Hepatocyte-specific deletion of farnesoid X receptor delays but does not inhibit liver regeneration after partial hepatectomy in mice. Hepatology. 2012 Dec; 56(6):2344-52.

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Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7814-9.

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MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. J Lipid Res. 2010 Jun; 51(6):1513-23.

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The SWI/SNF chromatin-remodeling complex modulates peripheral T cell activation and proliferation by controlling AP-1 expression. J Biol Chem. 2010 Jan 22; 285(4):2340-50.

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c-Jun amplification and overexpression are oncogenic in liposarcoma but not always sufficient to inhibit the adipocytic differentiation programme. J Pathol. 2009 Jul; 218(3):292-300.

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Genome-wide functional synergy between amplified and mutated genes in human breast cancer. Cancer Res. 2008 Nov 15; 68(22):9532-40.

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