Intercalating Agents

"Intercalating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.

Descriptor ID

D007364

MeSH Number(s)

D27.720.470.410.360

Concept/Terms

Intercalating Agents

Below are MeSH descriptors whose meaning is more general than "Intercalating Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Laboratory Chemicals [D27.720.470]
Indicators and Reagents [D27.720.470.410]
Intercalating Agents [D27.720.470.410.360]

Below are MeSH descriptors whose meaning is related to "Intercalating Agents".

Below are MeSH descriptors whose meaning is more specific than "Intercalating Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Intercalating Agents" by people in Harvard Catalyst Profiles by year, and whether "Intercalating Agents" was a major or minor topic of these publication.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 4 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1996	0	1	1
1997	0	1	1
1998	0	1	1
1999	0	1	1
2001	1	0	1
2003	0	1	1
2010	2	0	2
2012	0	1	1
2013	0	1	1
2015	1	1	2
2018	0	4	4
2020	1	0	1
2021	1	1	2

Below are the most recent publications written about "Intercalating Agents" by people in Profiles.

A DNA intercalating dye-based RT-qPCR alternative to diagnose SARS-CoV-2. RNA Biol. 2021 12; 18(12):2218-2225.

View in: PubMed
Colorimetric loop-mediated isothermal amplification (LAMP) for cost-effective and quantitative detection of SARS-CoV-2: the change in color in LAMP-based assays quantitatively correlates with viral copy number. Anal Methods. 2021 01 21; 13(2):169-178.

View in: PubMed
Design and synthesis of thiadiazolo-carboxamide bridged ß-carboline-indole hybrids: DNA intercalative topo-IIa inhibition with promising antiproliferative activity. Bioorg Chem. 2020 12; 105:104357.

View in: PubMed
Effects of corneal preservation conditions on human corneal endothelial cell culture. Exp Eye Res. 2019 02; 179:93-101.

View in: PubMed
In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy. Analyst. 2018 Oct 08; 143(20):4836-4839.

View in: PubMed
A novel molecular rotor facilitates detection of p53-DNA interactions using the Fluorescent Intercalator Displacement Assay. Sci Rep. 2018 08 28; 8(1):12946.

View in: PubMed
Synthesis of DNA interactive C3-trans-cinnamide linked ß-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors. Bioorg Med Chem. 2018 09 15; 26(17):4916-4929.

View in: PubMed
Sensing DNA through DNA Charge Transport. ACS Chem Biol. 2018 07 20; 13(7):1799-1809.

View in: PubMed
Synthesis, Spectral Properties and DFT Calculations of new Ruthenium (II) Polypyridyl Complexes; DNA Binding Affinity and in Vitro Cytotoxicity Activity. J Fluoresc. 2017 Jul; 27(4):1513-1530.

View in: PubMed
Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model. Small. 2016 Jan 20; 12(3):308-20.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Biochemistry
Nucleic Acids Res
Radiat Res
Inorg Chem
Chemphyschem
Chem Commun (Camb)
Chem Asian J
Bioorg Chem
Biochem Pharmacol
ACS Nano