Interleukin-10 Receptor alpha Subunit

"Interleukin-10 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subunit of the interleukin-10 receptor. It plays a role in receptor signaling by associating with JANUS KINASE 1.

Descriptor ID

D053709

MeSH Number(s)

D12.776.543.750.705.852.420.550.500

D23.050.301.264.035.409

D23.101.100.110.409

Concept/Terms

Interleukin-10 Receptor alpha Subunit

Below are MeSH descriptors whose meaning is more general than "Interleukin-10 Receptor alpha Subunit".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-10 [D12.776.543.750.705.852.420.550]
Interleukin-10 Receptor alpha Subunit [D12.776.543.750.705.852.420.550.500]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Surface [D23.050.301]
Antigens, Differentiation [D23.050.301.264]
Antigens, CD [D23.050.301.264.035]
Interleukin-10 Receptor alpha Subunit [D23.050.301.264.035.409]
Biological Markers [D23.101]
Antigens, Differentiation [D23.101.100]
Antigens, CD [D23.101.100.110]
Interleukin-10 Receptor alpha Subunit [D23.101.100.110.409]

Below are MeSH descriptors whose meaning is related to "Interleukin-10 Receptor alpha Subunit".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-10 Receptor alpha Subunit".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-10 Receptor alpha Subunit" by people in Harvard Catalyst Profiles by year, and whether "Interleukin-10 Receptor alpha Subunit" was a major or minor topic of these publication.

Bar chart showing 15 publications over 10 distinct years, with a maximum of 2 publications in 2013 and 2016 and 2020 and 2021 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	1	0	1
2012	1	0	1
2013	1	1	2
2014	1	0	1
2015	0	1	1
2016	1	1	2
2017	0	1	1
2020	2	0	2
2021	1	1	2
2022	1	1	2

Below are the most recent publications written about "Interleukin-10 Receptor alpha Subunit" by people in Profiles.

Pathogenic Interleukin-10 Receptor Alpha Variants in Humans - Balancing Natural Selection and Clinical Implications. J Clin Immunol. 2023 02; 43(2):495-511.

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CCR2 promotes monocyte recruitment and intestinal inflammation in mice lacking the interleukin-10 receptor. Sci Rep. 2022 01 10; 12(1):452.

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Importance of early detection of infantile inflammatory bowel disease with defective IL-10 pathway: A case report. Medicine (Baltimore). 2021 May 28; 100(21):e25868.

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Knockout-Induced Pluripotent Stem Cells for Disease and Therapy Modeling of IL-10-Associated Primary Immunodeficiencies. Hum Gene Ther. 2021 01; 32(1-2):77-95.

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IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma. Blood. 2020 10 01; 136(14):1657-1669.

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Modulation of IL10 and Its Receptor Subunits in Normal and Progesterone-Prolonged Gestation in the Mouse. Reprod Sci. 2020 02; 27(2):555-560.

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Increased Mucosal IL-22 Production of an IL-10RA Mutation Patient Following Anakin Treatment Suggests Further Mechanism for Mucosal Healing. J Clin Immunol. 2017 02; 37(2):104-107.

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Interleukin 1ß Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency. Gastroenterology. 2016 12; 151(6):1100-1104.

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Large B-Cell Lymphoma in an Adolescent Patient With Interleukin-10 Receptor Deficiency and History of Infantile Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2016 07; 63(1):e15-7.

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Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. Gastroenterology. 2015 Nov; 149(6):1415-24.

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