"Acarbose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitor of alpha glucosidase that retards the digestion and absorption of carbohydrates in the small intestine and hence reduces the increase in blood-glucose concentrations after a carbohydrate load. It is given orally to non-insulin dependent diabetes mellitus patients where diet modification or oral hypoglycemic agents do not control their condition. (From Martindale The Extra Pharmacopoeia, 31st ed)
Concept/Terms
Glumida- Glumida
- Lasa Brand of Acarbose
Precose- Precose
- Prandase
- Glucor
- Bayer Brand of Acarbose
- Glucobay
Below are MeSH descriptors whose meaning is more general than "Acarbose".
Below are MeSH descriptors whose meaning is more specific than "Acarbose".
This graph shows the total number of publications written about "Acarbose" by people in Harvard Catalyst Profiles by year, and whether "Acarbose" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Acarbose" by people in Profiles.
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Design, synthesis and antidiabetic study of triazole clubbed indole derivatives as a-glucosidase inhibitors. Bioorg Chem. 2023 10; 139:106750.
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A time to revisit the two oldest prandial anti-diabetes agents: acarbose and repaglinide. Endocrine. 2020 11; 70(2):307-313.
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International consensus on the diagnosis and management of dumping syndrome. Nat Rev Endocrinol. 2020 08; 16(8):448-466.
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Acarbose versus Repaglinide in Diabetes Treatment: A New Appraisal of Two Old Rivals. Am J Med Sci. 2020 04; 359(4):212-217.
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The Use of Non-insulin Agents in Gestational Diabetes: Clinical Considerations in Tailoring Therapy. Curr Diab Rep. 2019 12 06; 19(12):158.
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Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an a-glucosidase inhibitor or a Nrf2-inducer. Aging Cell. 2016 10; 15(5):872-84.
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Using oral agents to manage gestational diabetes: what have we learned? Curr Diab Rep. 2015 Feb; 15(2):570.
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Profound defects in ß-cell function in screen-detected type 2 diabetes are not improved with glucose-lowering treatment in the Early Diabetes Intervention Program (EDIP). Diabetes Metab Res Rev. 2014 Nov; 30(8):767-76.
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Effect of acarbose to delay progression of carotid intima-media thickness in early diabetes. Diabetes Metab Res Rev. 2013 Oct; 29(7):582-91.
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The cytosolic and extracellular proteomes of Actinoplanes sp. SE50/110 led to the identification of gene products involved in acarbose metabolism. J Biotechnol. 2013 Aug 20; 167(2):178-89.