Eukaryotic Initiation Factor-1

"Eukaryotic Initiation Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.

Descriptor ID

D015977

MeSH Number(s)

D12.776.835.725.868.124

Concept/Terms

Eukaryotic Initiation Factor-1

Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Ribosomal Proteins [D12.776.835]
Peptide Initiation Factors [D12.776.835.725]
Eukaryotic Initiation Factors [D12.776.835.725.868]
Eukaryotic Initiation Factor-1 [D12.776.835.725.868.124]

Below are MeSH descriptors whose meaning is related to "Eukaryotic Initiation Factor-1".

Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Eukaryotic Initiation Factor-1" by people in Harvard Catalyst Profiles by year, and whether "Eukaryotic Initiation Factor-1" was a major or minor topic of these publication.

Bar chart showing 19 publications over 11 distinct years, with a maximum of 3 publications in 2013 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2003	2	0	2
2005	1	0	1
2007	1	0	1
2009	1	0	1
2012	1	0	1
2013	3	0	3
2015	1	1	2
2016	0	2	2
2017	0	3	3
2018	2	0	2

Below are the most recent publications written about "Eukaryotic Initiation Factor-1" by people in Profiles.

EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC. Cancer Discov. 2019 02; 9(2):264-281.

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Whole-exome sequencing of a meningeal melanocytic tumour reveals activating CYSLTR2 and EIF1AX hotspot mutations and similarities to uveal melanoma. Brain Tumor Pathol. 2018 04; 35(2):127-130.

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Identifying RISC Components Using Ago2 Immunoprecipitation and Mass Spectrometry. Methods Mol Biol. 2018; 1720:149-159.

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Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma. Cancer Cell. 2017 08 14; 32(2):204-220.e15.

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Systematic genomic and translational efficiency studies of uveal melanoma. PLoS One. 2017; 12(6):e0178189.

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Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5. Cell Rep. 2017 03 14; 18(11):2651-2663.

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Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression. J Biol Chem. 2016 Jun 24; 291(26):13780-8.

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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers. J Clin Invest. 2016 Mar 01; 126(3):1052-66.

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Sex chromosome-to-autosome transposition events counter Y-chromosome gene loss in mammals. Genome Biol. 2015 May 28; 16:104.

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eIF1A augments Ago2-mediated Dicer-independent miRNA biogenesis and RNA interference. Nat Commun. 2015 May 28; 6:7194.

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