"Metformin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Concept/Terms
Metformin- Metformin
- Dimethylguanylguanidine
- Dimethylbiguanidine
Below are MeSH descriptors whose meaning is more general than "Metformin".
Below are MeSH descriptors whose meaning is more specific than "Metformin".
This graph shows the total number of publications written about "Metformin" by people in Harvard Catalyst Profiles by year, and whether "Metformin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1996 | 2 | 1 | 3 |
1998 | 0 | 1 | 1 |
1999 | 2 | 1 | 3 |
2000 | 2 | 2 | 4 |
2001 | 2 | 0 | 2 |
2002 | 3 | 2 | 5 |
2003 | 2 | 6 | 8 |
2004 | 6 | 3 | 9 |
2005 | 4 | 5 | 9 |
2006 | 1 | 5 | 6 |
2007 | 6 | 7 | 13 |
2008 | 3 | 10 | 13 |
2009 | 11 | 6 | 17 |
2010 | 7 | 6 | 13 |
2011 | 6 | 3 | 9 |
2012 | 10 | 13 | 23 |
2013 | 14 | 12 | 26 |
2014 | 22 | 12 | 34 |
2015 | 23 | 6 | 29 |
2016 | 26 | 11 | 37 |
2017 | 24 | 20 | 44 |
2018 | 15 | 16 | 31 |
2019 | 25 | 11 | 36 |
2020 | 25 | 9 | 34 |
2021 | 22 | 4 | 26 |
2022 | 29 | 1 | 30 |
2023 | 35 | 0 | 35 |
2024 | 6 | 0 | 6 |
Below are the most recent publications written about "Metformin" by people in Profiles.
-
The Use of Rescue Insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care. 2024 Apr 01; 47(4):638-645.
-
Differential Effects of Type 2 Diabetes Treatment Regimens on Diabetes Distress and Depressive Symptoms in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care. 2024 Apr 01; 47(4):610-619.
-
The impact of metformin on weight and metabolic parameters in patients with obesity: A systematic review and meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2024 May; 26(5):1850-1867.
-
Effectiveness of metformin for the reversal of cold-ischemia-induced damage in hepatosteatosis. Clin Res Hepatol Gastroenterol. 2024 Apr; 48(4):102314.
-
Growth Hormone Mediators and Glycemic Control in Youths With Type 2 Diabetes: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024 Feb 05; 7(2):e240447.
-
Metformin and adipose-derived stem cell combination therapy alleviates radiation-induced skin fibrosis in mice. Stem Cell Res Ther. 2024 01 08; 15(1):13.
-
Human trials exploring anti-aging medicines. Cell Metab. 2024 02 06; 36(2):354-376.
-
Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma. Neuro Oncol. 2023 12 08; 25(12):2165-2176.
-
Metformin Does not Affect Outcomes in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Therapy and Resection. Am Surg. 2024 Apr; 90(4):858-865.
-
Investigating the ability to adhere to cardiometabolic medications with different properties: a retrospective cohort study of >500 000 patients in the USA. BMJ Open. 2023 11 10; 13(11):e075840.