Serum Response Element

"Serum Response Element" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A DNA sequence that is found in the promoter region of many growth-related genes. The regulatory transcription factor SERUM RESPONSE FACTOR binds to and regulates the activity of genes containing this element.

Descriptor ID

D027602

MeSH Number(s)

G02.111.570.080.689.330.700.800

G02.111.570.080.689.675.700.800

G05.360.080.689.330.700.800

G05.360.080.689.675.700.800

G05.360.340.024.340.137.750.249.765.800

G05.360.340.024.340.137.750.680.765.800

Concept/Terms

Serum Response Element

Below are MeSH descriptors whose meaning is more general than "Serum Response Element".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Base Sequence [G02.111.570.080]
Regulatory Sequences, Nucleic Acid [G02.111.570.080.689]
Enhancer Elements, Genetic [G02.111.570.080.689.330]
Response Elements [G02.111.570.080.689.330.700]
Serum Response Element [G02.111.570.080.689.330.700.800]
Promoter Regions, Genetic [G02.111.570.080.689.675]
Response Elements [G02.111.570.080.689.675.700]
Serum Response Element [G02.111.570.080.689.675.700.800]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Base Sequence [G05.360.080]
Regulatory Sequences, Nucleic Acid [G05.360.080.689]
Enhancer Elements, Genetic [G05.360.080.689.330]
Response Elements [G05.360.080.689.330.700]
Serum Response Element [G05.360.080.689.330.700.800]
Promoter Regions, Genetic [G05.360.080.689.675]
Response Elements [G05.360.080.689.675.700]
Serum Response Element [G05.360.080.689.675.700.800]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Gene Components [G05.360.340.024.340.137]
Regulatory Elements, Transcriptional [G05.360.340.024.340.137.750]
Enhancer Elements, Genetic [G05.360.340.024.340.137.750.249]
Response Elements [G05.360.340.024.340.137.750.249.765]
Serum Response Element [G05.360.340.024.340.137.750.249.765.800]
Promoter Regions, Genetic [G05.360.340.024.340.137.750.680]
Response Elements [G05.360.340.024.340.137.750.680.765]
Serum Response Element [G05.360.340.024.340.137.750.680.765.800]

Below are MeSH descriptors whose meaning is related to "Serum Response Element".

Below are MeSH descriptors whose meaning is more specific than "Serum Response Element".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Serum Response Element" by people in Harvard Catalyst Profiles by year, and whether "Serum Response Element" was a major or minor topic of these publication.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2001 and 2002 and 2003 and 2004 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	1	0	1
2003	1	0	1
2004	1	0	1
2013	1	0	1

Below are the most recent publications written about "Serum Response Element" by people in Profiles.

Smooth Muscle Cell Genome Browser: Enabling the Identification of Novel Serum Response Factor Target Genes. PLoS One. 2015; 10(8):e0133751.

View in: PubMed
G-protein coupled receptor 56 promotes myoblast fusion through serum response factor- and nuclear factor of activated T-cell-mediated signalling but is not essential for muscle development in vivo. FEBS J. 2013 Dec; 280(23):6097-113.

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The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice. J Clin Invest. 2011 Jun; 121(6):2447-56.

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Cyclic GMP kinase and RhoA Ser188 phosphorylation integrate pro- and antifibrotic signals in blood vessels. Mol Cell Biol. 2009 Nov; 29(22):6018-32.

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Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. Biochemistry. 2008 Jan 15; 47(2):744-52.

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Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42. J Biol Chem. 2008 Jan 25; 283(4):1946-53.

View in: PubMed
Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol Biol Cell. 2007 Mar; 18(3):755-67.

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The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression. Mol Cell Biol. 2005 Dec; 25(24):10853-62.

View in: PubMed
Wave2 activates serum response element via its VCA region and functions downstream of Rac. Exp Cell Res. 2004 Dec 10; 301(2):331-7.

View in: PubMed
Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells. J Biol Chem. 2005 Feb 04; 280(5):3286-94.

View in: PubMed

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