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Leucine Zippers

"Leucine Zippers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.


publications
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This graph shows the total number of publications written about "Leucine Zippers" by people in Harvard Catalyst Profiles by year, and whether "Leucine Zippers" was a major or minor topic of these publication.
Bar chart showing 74 publications over 21 distinct years, with a maximum of 10 publications in 1996
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.