Cyclic Nucleotide Phosphodiesterases, Type 7
"Cyclic Nucleotide Phosphodiesterases, Type 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC AMP. Several isoforms of the enzyme type exist, each with its own tissue localization. The isoforms are encoded by at least two genes and are a product of multiple alternative splicing of their mRNAs.
MeSH Number(s)
D08.811.277.352.640.150.700
D12.644.360.008.700
D12.776.476.008.700
Concept/Terms
Cyclic Nucleotide Phosphodiesterases, Type 7- Cyclic Nucleotide Phosphodiesterases, Type 7
- Cyclic Nucleotide Phosphodiesterase PDE7 Family
- Phosphodiesterase-7
- Phosphodiesterase 7
- cAMP Phosphodiesterase-7
- cAMP Phosphodiesterase 7
- PDE7 Phosphodiesterases
Below are MeSH descriptors whose meaning is more general than "Cyclic Nucleotide Phosphodiesterases, Type 7".
Below are MeSH descriptors whose meaning is more specific than "Cyclic Nucleotide Phosphodiesterases, Type 7".
This graph shows the total number of publications written about "Cyclic Nucleotide Phosphodiesterases, Type 7" by people in Harvard Catalyst Profiles by year, and whether "Cyclic Nucleotide Phosphodiesterases, Type 7" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
Below are the most recent publications written about "Cyclic Nucleotide Phosphodiesterases, Type 7" by people in Profiles.
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Anti-inflammatory effects of novel barbituric acid derivatives in T lymphocytes. Int Immunopharmacol. 2016 Sep; 38:223-32.
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A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15.
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A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice. PLoS One. 2010 Jul 07; 5(7):e11464.
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New classes of PDE7 inhibitors identified by a fission yeast-based HTS. J Biomol Screen. 2010 Apr; 15(4):359-67.
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Phosphodiesterase 7A inhibitor ASB16165 impairs proliferation of keratinocytes in vitro and in vivo. Eur J Pharmacol. 2010 May 10; 633(1-3):93-7.
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Inhibition of phosphodiesterase 7A ameliorates Concanavalin A-induced hepatitis in mice. Int Immunopharmacol. 2009 Oct; 9(11):1347-51.
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Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells. Cell Immunol. 2009; 258(2):147-51.
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ASB16165, a phosphodiesterase 7A inhibitor, reduces cutaneous TNF-alpha level and ameliorates skin edema in phorbol ester 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation model in mice. Eur J Pharmacol. 2009 Jun 24; 613(1-3):163-6.
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ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-gamma production by mouse activated T lymphocytes. Immunol Lett. 2009 Feb 21; 122(2):193-7.
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Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte. Int Immunopharmacol. 2009 Jan; 9(1):97-102.