Nondisjunction, Genetic

"Nondisjunction, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The failure of homologous CHROMOSOMES or CHROMATIDS to segregate during MITOSIS or MEIOSIS with the result that one daughter cell has both of a pair of parental chromosomes or chromatids and the other has none.

Descriptor ID

D009630

MeSH Number(s)

C23.550.210.645

G05.355.105.220.625.620

G05.355.600.620

Concept/Terms

Nondisjunction, Genetic

Below are MeSH descriptors whose meaning is more general than "Nondisjunction, Genetic".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Chromosome Aberrations [C23.550.210]
Nondisjunction, Genetic [C23.550.210.645]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Processes [G05.355]
Cell Division [G05.355.105]
Cell Nucleus Division [G05.355.105.220]
Chromosome Segregation [G05.355.105.220.625]
Nondisjunction, Genetic [G05.355.105.220.625.620]
Mutagenesis [G05.355.600]
Nondisjunction, Genetic [G05.355.600.620]

Below are MeSH descriptors whose meaning is more specific than "Nondisjunction, Genetic".

Nondisjunction, Genetic
Uniparental Disomy

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nondisjunction, Genetic" by people in Harvard Catalyst Profiles by year, and whether "Nondisjunction, Genetic" was a major or minor topic of these publication.

Bar chart showing 10 publications over 10 distinct years, with a maximum of 1 publications in 1994 and 1995 and 1999 and 2003 and 2005 and 2006 and 2008 and 2014 and 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1999	0	1	1
2003	0	1	1
2005	1	0	1
2006	0	1	1
2008	0	1	1
2014	0	1	1
2016	0	1	1
2020	0	1	1

Below are the most recent publications written about "Nondisjunction, Genetic" by people in Profiles.

Insights into variation in meiosis from 31,228 human sperm genomes. Nature. 2020 07; 583(7815):259-264.

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Bloom Syndrome Helicase Promotes Meiotic Crossover Patterning and Homolog Disjunction. Curr Biol. 2017 Jan 09; 27(1):96-102.

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The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans. G3 (Bethesda). 2016 04 07; 6(4):1031-47.

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Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible. Curr Biol. 2014 Mar 17; 24(6):630-7.

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Altered patterns of multiple recombinant events are associated with nondisjunction of chromosome 21. Hum Genet. 2012 Jul; 131(7):1039-46.

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Investigation of factors associated with paternal nondisjunction of chromosome 21. Am J Med Genet A. 2009 Aug; 149A(8):1685-90.

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Effects of age on meiosis in budding yeast. Dev Cell. 2009 Jun; 16(6):844-55.

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Maternal age and risk for trisomy 21 assessed by the origin of chromosome nondisjunction: a report from the Atlanta and National Down Syndrome Projects. Hum Genet. 2009 Feb; 125(1):41-52.

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Drosophila hold'em is required for a subset of meiotic crossovers and interacts with the dna repair endonuclease complex subunits MEI-9 and ERCC1. Genetics. 2009 Jan; 181(1):335-40.

View in: PubMed
When 2+2=5: the origins and fates of aneuploid and tetraploid cells. Biochim Biophys Acta. 2008 Sep; 1786(1):4-14.

View in: PubMed

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