"Genes, fms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of genes originally isolated from the Susan McDonough strain of feline sarcoma virus (SARCOMA VIRUSES, FELINE). The proto-oncogene fms (c-fms) codes for the MCSF receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR). The oncogene fms (v-fms) codes for ONCOGENE PROTEIN GP140(V-FMS) which is a mutated form of the MCSF. The human c-fms gene is located between 5q33.2 and 5q33.3.
MeSH Number(s)
G05.360.340.024.340.375.500.791.325
Concept/Terms
c-fms Genes- c-fms Genes
- Gene, c-fms
- Genes, c-fms
- c fms Genes
- c-fms Gene
- c-fms Proto-Oncogenes
- Proto-Oncogene, c-fms
- Proto-Oncogenes, c-fms
- c fms Proto Oncogenes
- c-fms Proto-Oncogene
v-fms Genes- v-fms Genes
- Gene, v-fms
- Genes, v-fms
- v fms Genes
- v-fms Gene
- v-fms Oncogenes
- Oncogene, v-fms
- Oncogenes, v-fms
- v fms Oncogenes
- v-fms Oncogene
Below are MeSH descriptors whose meaning is more general than "Genes, fms".
Below are MeSH descriptors whose meaning is more specific than "Genes, fms".
This graph shows the total number of publications written about "Genes, fms" by people in Harvard Catalyst Profiles by year, and whether "Genes, fms" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
Below are the most recent publications written about "Genes, fms" by people in Profiles.
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c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis. Arthritis Res Ther. 2010; 12(1):R32.
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Heat shock factor 1 contains two functional domains that mediate transcriptional repression of the c-fos and c-fms genes. J Biol Chem. 2003 Feb 14; 278(7):4687-98.
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NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells. Biochem Biophys Res Commun. 2002 Mar 08; 291(4):1071-80.
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Heterogeneity among cells that express osteoclast-associated genes in developing bone. Endocrinology. 1998 Jan; 139(1):340-9.
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CSF-1 deficiency in mice results in abnormal brain development. Development. 1996 Sep; 122(9):2661-72.
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Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells. J Clin Invest. 1995 Mar; 95(3):1133-9.
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All-trans retinoic acid induces monocyte growth factor receptor (c-fms) gene expression in HL-60 leukemia cells. Leukemia. 1993 Mar; 7(3):458-62.
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Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2814-8.