Angiopoietin-1

"Angiopoietin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.

Descriptor ID

D042683

MeSH Number(s)

D12.644.276.100.100.100

D12.776.467.100.100.100

D23.529.100.100.100

Concept/Terms

Angiopoietin-1

Below are MeSH descriptors whose meaning is more general than "Angiopoietin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Angiogenic Proteins [D12.644.276.100]
Angiopoietins [D12.644.276.100.100]
Angiopoietin-1 [D12.644.276.100.100.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Angiogenic Proteins [D12.776.467.100]
Angiopoietins [D12.776.467.100.100]
Angiopoietin-1 [D12.776.467.100.100.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Angiogenic Proteins [D23.529.100]
Angiopoietins [D23.529.100.100]
Angiopoietin-1 [D23.529.100.100.100]

Below are MeSH descriptors whose meaning is related to "Angiopoietin-1".

Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiopoietin-1" by people in Harvard Catalyst Profiles by year, and whether "Angiopoietin-1" was a major or minor topic of these publication.

Bar chart showing 73 publications over 23 distinct years, with a maximum of 6 publications in 2002 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1999	0	1	1
2000	0	4	4
2001	0	2	2
2002	0	6	6
2003	1	3	4
2004	2	1	3
2005	0	4	4
2006	1	2	3
2007	3	2	5
2008	2	4	6
2009	1	1	2
2010	3	1	4
2011	1	1	2
2012	3	2	5
2013	2	1	3
2015	2	1	3
2016	1	1	2
2017	2	1	3
2018	0	3	3
2019	2	1	3
2020	1	0	1
2022	0	3	3

Below are the most recent publications written about "Angiopoietin-1" by people in Profiles.

Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease. Diabetes. 2022 12 01; 71(12):2664-2676.

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Microvascular remodeling and altered angiogenic signaling in human kidneys distal to occlusive atherosclerotic renal artery stenosis. Nephrol Dial Transplant. 2022 09 22; 37(10):1844-1856.

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Role of Angiopoietin-Tie axis in vascular and lymphatic systems and therapeutic interventions. Pharmacol Res. 2022 08; 182:106331.

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The Angiopoietin-Tie2 Pathway in Critical Illness. Crit Care Clin. 2020 Apr; 36(2):201-216.

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Physician Judgment and Circulating Biomarkers Predict 28-Day Mortality in Emergency Department Patients. Crit Care Med. 2019 11; 47(11):1513-1521.

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Activated hepatic stellate cells promote angiogenesis in hepatocellular carcinoma by secreting angiopoietin-1. J Cell Biochem. 2020 02; 121(2):1441-1451.

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Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock. Int J Med Sci. 2019; 16(2):318-323.

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Multiplexed, high-throughput measurements of cell contraction and endothelial barrier function. Lab Invest. 2019 01; 99(1):138-145.

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Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age. J Pediatr. 2018 10; 201:40-48.e4.

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Neonatal systemic inflammation and the risk of low scores on measures of reading and mathematics achievement at age 10 years among children born extremely preterm. Int J Dev Neurosci. 2018 May; 66:45-53.

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