Harvard Catalyst Profiles

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4-Quinolones

"4-Quinolones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.


This graph shows the total number of publications written about "4-Quinolones" by people in Harvard Catalyst Profiles by year, and whether "4-Quinolones" was a major or minor topic of these publication.
Bar chart showing 9 publications over 6 distinct years, with a maximum of 2 publications in 1995 and 1998 and 2003
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.