"Biogenic Polyamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Biogenic amines having more than one amine group. These are long-chain aliphatic compounds that contain multiple amino and/or imino groups. Because of the linear arrangement of positive charge on these molecules, polyamines bind electrostatically to ribosomes, DNA, and RNA.
Below are MeSH descriptors whose meaning is more general than "Biogenic Polyamines".
Below are MeSH descriptors whose meaning is more specific than "Biogenic Polyamines".
This graph shows the total number of publications written about "Biogenic Polyamines" by people in Harvard Catalyst Profiles by year, and whether "Biogenic Polyamines" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
Below are the most recent publications written about "Biogenic Polyamines" by people in Profiles.
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Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy. J Biol Chem. 2020 05 08; 295(19):6263-6277.
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Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma. J Clin Invest. 2018 10 01; 128(10):4682-4696.
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Polyamine catabolism is enhanced after traumatic brain injury. J Neurotrauma. 2010 Mar; 27(3):515-25.
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Targeting polyamines and biogenic amines by green tea epigallocatechin-3-gallate. Amino Acids. 2010 Feb; 38(2):519-23.
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The polyamines regulate endothelial cell survival during hypoxic stress through PI3K/AKT and MCL-1. Biochem Biophys Res Commun. 2009 Mar 06; 380(2):413-8.
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ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma. Cancer Res. 2008 Dec 01; 68(23):9735-45.
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Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase. Cancer Res. 2008 Nov 15; 68(22):9291-301.
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Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation. Int J Oncol. 2008 Apr; 32(4):749-56.
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Lipoplex structures and their distinct cellular pathways. Adv Genet. 2005; 53:119-55.
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Antitumor effects of bis(ethyl)polyamine analogs on mammary tumor development in FVB/NTgN (MMTVneu) transgenic mice. Cancer Lett. 1999 Nov 01; 146(1):15-23.