Fura-2

"Fura-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A fluorescent calcium chelating agent which is used to study intracellular calcium in many tissues. The fluorescent and chelating properties of Fura-2 aid in the quantitation of endothelial cell injury, in monitoring ATP-dependent calcium uptake by membrane vesicles, and in the determination of the relationship between cytoplasmic free calcium and oxidase activation in rat neutrophils.

Descriptor ID

D016257

MeSH Number(s)

D03.383.129.462.285

D03.438.127.250

Concept/Terms

Fura-2

Below are MeSH descriptors whose meaning is more general than "Fura-2".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Oxazoles [D03.383.129.462]
Fura-2 [D03.383.129.462.285]
Heterocyclic Compounds, 2-Ring [D03.438]
Benzofurans [D03.438.127]
Fura-2 [D03.438.127.250]

Below are MeSH descriptors whose meaning is related to "Fura-2".

Below are MeSH descriptors whose meaning is more specific than "Fura-2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fura-2" by people in Harvard Catalyst Profiles by year, and whether "Fura-2" was a major or minor topic of these publication.

Bar chart showing 58 publications over 24 distinct years, with a maximum of 8 publications in 1994

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	7	8
1995	1	4	5
1996	1	0	1
1997	0	4	4
1998	0	4	4
1999	0	2	2
2000	0	3	3
2001	0	6	6
2002	0	1	1
2003	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	2	2
2009	0	1	1
2010	0	1	1
2011	0	3	3
2012	0	3	3
2014	0	1	1
2015	0	1	1
2017	0	2	2
2018	0	3	3
2019	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Fura-2" by people in Profiles.

Functional maturation of kidney organoid tubules: PIEZO1-mediated Ca2+ signaling. Am J Physiol Cell Physiol. 2023 03 01; 324(3):C757-C768.

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Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators. Sci Rep. 2022 09 29; 12(1):16305.

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Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells. FASEB J. 2019 07; 33(7):8468-8478.

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Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells. Exp Eye Res. 2019 03; 180:53-62.

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Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3543-3553.

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Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells. Exp Eye Res. 2018 08; 173:64-72.

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Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways. Invest Ophthalmol Vis Sci. 2017 09 01; 58(11):4530-4544.

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Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells. J Vis Exp. 2017 03 16; (121).

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Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP. PLoS One. 2015; 10(8):e0135060.

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p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1779-84.

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