Receptors, Prostaglandin E, EP2 Subtype
"Receptors, Prostaglandin E, EP2 Subtype" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of prostaglandin E receptors that specifically couples to GS ALPHA GTP-BINDING PROTEIN SUBUNITS and subsequently activates ADENYLATE CYCLASE.
MeSH Number(s)
D12.776.543.750.100.200.700.600.200
Concept/Terms
Receptors, Prostaglandin E, EP2 Subtype- Receptors, Prostaglandin E, EP2 Subtype
- Prostanoid Receptor EP2
- EP2, Prostanoid Receptor
- Receptor EP2, Prostanoid
- PGE Receptor, EP2 Subtype
- Prostaglandin E Receptor 2
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E, EP2 Subtype".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E, EP2 Subtype".
This graph shows the total number of publications written about "Receptors, Prostaglandin E, EP2 Subtype" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Prostaglandin E, EP2 Subtype" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Prostaglandin E, EP2 Subtype" by people in Profiles.
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Dual Blockade of EP2 and EP4 Signaling is Required for Optimal Immune Activation and Antitumor Activity Against Prostaglandin-Expressing Tumors. Cancer Res Commun. 2023 08; 3(8):1486-1500.
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Activated ß-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity. Nat Immunol. 2018 12; 19(12):1391-1402.
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Epithelial Cells Induce a Cyclo-Oxygenase-1-Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype. Am J Respir Cell Mol Biol. 2017 12; 57(6):683-691.
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Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. J Biol Chem. 2017 05 19; 292(20):8195-8206.
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Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands. FEBS J. 2016 11; 283(21):3931-3940.
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Impaired E Prostanoid2 Expression and Resistance to Prostaglandin E2 in Nasal Polyp Fibroblasts from Subjects with Aspirin-Exacerbated Respiratory Disease. Am J Respir Cell Mol Biol. 2016 Jan; 54(1):34-40.
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Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis. Proc Natl Acad Sci U S A. 2015 Aug 04; 112(31):9716-21.
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Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nat Med. 2015 Apr; 21(4):327-34.
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Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors. Biochim Biophys Acta. 2015 Apr; 1851(4):414-21.
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Association between length of gestation and cervical DNA methylation of PTGER2 and LINE 1-HS. Epigenetics. 2014 Aug; 9(8):1083-91.