Receptors, Adrenergic, beta-1
"Receptors, Adrenergic, beta-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
MeSH Number(s)
D12.776.543.750.070.300.300.340.700
D12.776.543.750.100.150.300.340.700
D12.776.543.750.720.300.300.300.340.100
Concept/Terms
Receptors, Adrenergic, beta-1- Receptors, Adrenergic, beta-1
- Adrenergic Receptor, beta-1
- Adrenergic Receptor, beta 1
- Receptor, beta-1 Adrenergic
- beta-1 Adrenergic Receptor
- beta 1 Adrenergic Receptor
- Receptor, Adrenergic, beta-1
- Receptors, beta-1 Adrenergic
- Receptors, beta 1 Adrenergic
- Adrenergic beta-1 Receptors
- Adrenergic beta 1 Receptors
- Receptors, Adrenergic beta-1
- beta-1 Receptors, Adrenergic
- beta-1 Adrenergic Receptors
- Adrenergic Receptors, beta-1
- beta 1 Adrenergic Receptors
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.070]
- Receptors, Catecholamine [D12.776.543.750.070.300]
- Receptors, Adrenergic [D12.776.543.750.070.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.070.300.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.070.300.300.340.700]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Catecholamine [D12.776.543.750.100.150]
- Receptors, Adrenergic [D12.776.543.750.100.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.100.150.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.100.150.300.340.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Biogenic Amine [D12.776.543.750.720.300]
- Receptors, Catecholamine [D12.776.543.750.720.300.300]
- Receptors, Adrenergic [D12.776.543.750.720.300.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.300.300.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.720.300.300.300.340.100]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-1".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-1" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Adrenergic, beta-1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 2 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Receptors, Adrenergic, beta-1" by people in Profiles.
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Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype. Circ Arrhythm Electrophysiol. 2021 08; 14(8):e009591.
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ß3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis. JCI Insight. 2021 06 08; 6(11).
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Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome. J Pediatr. 2020 07; 222:213-220.e5.
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Effects of ß1-adrenergic receptor blockade on the cerebral microcirculation in the normal state and during global brain ischemia/reperfusion injury in rabbits. BMC Pharmacol Toxicol. 2020 02 21; 21(1):13.
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A Rare Mutation of ß1-Adrenergic Receptor Affects Sleep/Wake Behaviors. Neuron. 2019 09 25; 103(6):1044-1055.e7.
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Adrenoceptor-related decrease in serum triglycerides is independent of PPARa activation. FEBS J. 2019 11; 286(21):4328-4341.
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Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial. JACC Heart Fail. 2019 07; 7(7):586-598.
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The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial ß1-adrenergic receptor expression and signaling. J Biol Chem. 2019 02 15; 294(7):2500-2518.
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A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial. Am Heart J. 2018 05; 199:51-58.
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Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial. J Thorac Cardiovasc Surg. 2017 11; 154(5):1703-1710.e3.