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Roxane Marcelle Regine Darbousset, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Darbousset R. Exploring Platelet Dysregulation in Congenital Heart Disease: Novel Findings From Mass Cytometry. Arterioscler Thromb Vasc Biol. 2024 Dec; 44(12):2540-2542. PMID: 39417230.
    Citations:
    Fields: VasVascular Diseases
  2. Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, Aguiar VRC, Chiu DJ, Westra HJ, Gutierrez-Arcelus M, Weirauch MT, Raychaudhuri S, Rao DA, Nigrovic PA. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nat Commun. 2024 Mar 09; 15(1):2150. PMID: 38459032; PMCID: PMC10923805.
    Citations: 1
    Fields: BioBiologySciScienceTranslation:HumansCells
  3. Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P, Chang MH, Wactor A, Wauford BM, Todd MJC, Wei K, Li Y, Levescot A, Iwakura Y, Pascual V, Baldwin NE, Quartier P, Li T, Gianatasio MT, Hasserjian RP, Henderson LA, Sykes DB, Mellins ED, Canna SW, Charles JF, Nigrovic PA, Lee PY. mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nat Commun. 2022 11 28; 13(1):6915. PMID: 36443301; PMCID: PMC9705324.
    Citations: 12
    Fields: BioBiologySciScienceTranslation:HumansAnimals
  4. Huang FY, Cunin P, Radtke FA, Darbousset R, Grieshaber-Bouyer R, Nigrovic PA. Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis. Blood Adv. 2022 04 12; 6(7):2081-2091. PMID: 34872109; PMCID: PMC9006297.
    Citations: 2
    Fields: HemHematologyTranslation:AnimalsCells
  5. Crescence L, Darbousset R, Caroff E, Hubler F, Riederer MA, Panicot-Dubois L, Dubois C. Selatogrel, a reversible P2Y12 receptor antagonist, has reduced off-target interference with haemostatic factors in a mouse thrombosis model. Thromb Res. 2021 04; 200:133-140. PMID: 33610885.
    Citations: 10
    Fields: VasVascular DiseasesTranslation:AnimalsCells
  6. Makhloufi C, Crescence L, Darbousset R, McKay N, Massy ZA, Dubois C, Panicot-Dubois L, Burtey S, Poitevin S. Assessment of Thrombotic and Bleeding Tendency in Two Mouse Models of Chronic Kidney Disease: Adenine-Diet and 5/6th Nephrectomy. TH Open. 2020 Apr; 4(2):e66-e76. PMID: 32309772; PMCID: PMC7162676.
    Citations: 8
  7. Jackson SP, Darbousset R, Schoenwaelder SM. Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms. Blood. 2019 02 28; 133(9):906-918. PMID: 30642917.
    Citations: 260
    Fields: HemHematologyTranslation:Humans
  8. Schoenwaelder SM, Darbousset R, Cranmer SL, Ramshaw HS, Orive SL, Sturgeon S, Yuan Y, Yao Y, Krycer JR, Woodcock J, Maclean J, Pitson S, Zheng Z, Henstridge DC, van der Wal D, Gardiner EE, Berndt MC, Andrews RK, James DE, Lopez AF, Jackson SP. Corrigendum: 14-3-3? regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function. Nat Commun. 2017 08 30; 8:16125. PMID: 28853434.
    Citations:
    Fields: BioBiologySciScience
  9. Schoenwaelder SM, Darbousset R, Cranmer SL, Ramshaw HS, Orive SL, Sturgeon S, Yuan Y, Yao Y, Krycer JR, Woodcock J, Maclean J, Pitson S, Zheng Z, Henstridge DC, van der Wal D, Gardiner EE, Berndt MC, Andrews RK, James DE, Lopez AF, Jackson SP. 14-3-3? regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function. Nat Commun. 2016 Sep 27; 7:12862. PMID: 27670677.
    Citations: 30
    Fields: BioBiologySciScience
  10. Mezouar S, Frère C, Darbousset R, Mege D, Crescence L, Dignat-George F, Panicot-Dubois L, Dubois C. Role of platelets in cancer and cancer-associated thrombosis: Experimental and clinical evidences. Thromb Res. 2016 Mar; 139:65-76. PMID: 26916298.
    Citations: 105
    Fields: VasVascular DiseasesTranslation:HumansAnimalsCells
  11. Darbousset R, Delierneux C, Mezouar S, Hego A, Lecut C, Guillaumat I, Riederer MA, Evans RJ, Dignat-George F, Panicot-Dubois L, Oury C, Dubois C. P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice. Blood. 2014 Oct 16; 124(16):2575-85. PMID: 25150292; PMCID: PMC4199960.
    Citations: 36
    Fields: HemHematologyTranslation:HumansAnimalsCells
  12. Hubert L, Darbousset R, Panicot-Dubois L, Robert S, Sabatier F, Fallague K, Dignat-George F, Dubois C. Neutrophils recruit and activate human endothelial colony-forming cells at the site of vessel injury via P-selectin glycoprotein ligand-1 and L-selectin. J Thromb Haemost. 2014 Jul; 12(7):1170-81. PMID: 24606340.
    Citations: 11
    Fields: HemHematologyTranslation:HumansAnimalsCells
  13. Mezouar S, Darbousset R, Dignat-George F, Panicot-Dubois L, Dubois C. Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo. Int J Cancer. 2015 Jan 15; 136(2):462-75. PMID: 24889539.
    Citations: 82
    Fields: NeoNeoplasmsTranslation:AnimalsCells
  14. Mezouar S, Mege D, Darbousset R, Farge D, Debourdeau P, Dignat-George F, Panicot-Dubois L, Dubois C. Involvement of platelet-derived microparticles in tumor progression and thrombosis. Semin Oncol. 2014 Jun; 41(3):346-58. PMID: 25023350.
    Citations: 56
    Fields: NeoNeoplasmsTranslation:HumansCells
  15. Darbousset R, Mezouar S, Dignat-George F, Panicot-Dubois L, Dubois C. Involvement of neutrophils in thrombus formation in living mice. Pathol Biol (Paris). 2014 Feb; 62(1):1-9. PMID: 24485849.
    Citations: 9
    Fields: BioBiologyPatPathologyTranslation:AnimalsCells
  16. Darbousset R, Thomas GM, Mezouar S, Frère C, Bonier R, Mackman N, Renné T, Dignat-George F, Dubois C, Panicot-Dubois L. Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation. Blood. 2012 Sep 06; 120(10):2133-43. PMID: 22837532.
    Citations: 145
    Fields: HemHematologyTranslation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.