Harvard Catalyst Profiles

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David Allen Barbie, M.D.

Concepts (448)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Lung Neoplasms352024132622.370 Why?
Proto-Oncogene Proteins p21(ras)13202317281.890 Why?
Small Cell Lung Carcinoma920244211.650 Why?
ras Proteins5201610521.380 Why?
Carcinoma, Non-Small-Cell Lung12202352511.320 Why?
Spheroids, Cellular620233291.180 Why?
Cell Line, Tumor462024169391.080 Why?
Exodeoxyribonucleases220241951.050 Why?
Protein Kinase Inhibitors17202356431.010 Why?
Membrane Proteins6202478500.950 Why?
Benzamides7201813690.920 Why?
Signal Transduction212024233760.900 Why?
Killer Cells, Natural6202422030.890 Why?
Interferons520247050.860 Why?
Nucleotides, Cyclic22020840.830 Why?
Drug Resistance, Neoplasm17202452530.750 Why?
Neoplasms252024220720.740 Why?
Phosphoproteins4202424400.730 Why?
Neoplasm Proteins4202136100.730 Why?
Pyrimidines8201830160.650 Why?
Endogenous Retroviruses220211110.620 Why?
Neoplasms, Experimental3202112290.610 Why?
Nasopharyngeal Neoplasms120192860.560 Why?
Platinum120182230.560 Why?
Mutation262024299320.530 Why?
Proto-Oncogene Proteins c-met220225670.520 Why?
Adenocarcinoma5202463150.520 Why?
Pyrimidinones120183840.520 Why?
Immunity, Innate5202430470.510 Why?
Retinoblastoma Protein920196700.500 Why?
Janus Kinase 312015770.500 Why?
Antineoplastic Agents112021136300.490 Why?
Mice462024812080.490 Why?
Tumor Microenvironment11202438440.480 Why?
Genes, ras320226550.480 Why?
Gene Deletion4202026680.480 Why?
Principal Component Analysis120179400.480 Why?
Molecular Targeted Therapy5202128030.470 Why?
Autophagy3201613370.440 Why?
Immunotherapy, Adoptive2202414540.440 Why?
Doxycycline120153410.440 Why?
Immunotherapy8202346420.440 Why?
Animals5620241679630.440 Why?
Gene Expression Regulation, Neoplastic12202485150.430 Why?
I-kappa B Kinase420192510.430 Why?
Autocrine Communication120141690.430 Why?
Pyridones120187920.430 Why?
MAP Kinase Kinase 1420203310.420 Why?
Antineoplastic Combined Chemotherapy Protocols102020117120.390 Why?
Cell Survival5202057970.380 Why?
Neovascularization, Pathologic2202226400.370 Why?
Endothelial Cells4202435390.360 Why?
Proto-Oncogene Proteins B-raf2201720530.350 Why?
Chemokine CCL5320162150.350 Why?
Cyclin-Dependent Kinase 6320183460.340 Why?
Oncogene Protein p21(ras)12009680.340 Why?
Melanoma5202356970.340 Why?
Single-Cell Analysis1202123800.340 Why?
Humans10320247606210.330 Why?
Cell Nucleus6200529070.320 Why?
Pancreatitis1201611000.320 Why?
Microvessels220245720.320 Why?
Cytokines8202373430.320 Why?
Carcinoma, Renal Cell2202432180.320 Why?
Kidney Neoplasms2202443120.290 Why?
MicroRNAs2202137900.290 Why?
Proto-Oncogene Proteins3201444900.280 Why?
Microfluidics220226520.270 Why?
Drug Design3202110610.260 Why?
Receptors, CCR2220242150.260 Why?
Interleukin-64201732150.260 Why?
Mastocytosis, Systemic120061020.240 Why?
Pyrazoles1201519990.230 Why?
Tumor Cells, Cultured7202061310.230 Why?
Receptor, Macrophage Colony-Stimulating Factor12024940.230 Why?
Cyclin-Dependent Kinase 4220185560.230 Why?
Tumor Suppressor Protein p535202129190.230 Why?
RNA Interference4201828460.230 Why?
NF-kappa B3202324880.230 Why?
Enzyme Activation4201636020.230 Why?
Carbonic Anhydrases120241090.220 Why?
Janus Kinases320232500.220 Why?
Butyrate Response Factor 112022100.210 Why?
Tumor Suppressor Proteins2202128020.210 Why?
Pyridines1201528790.210 Why?
T-Lymphocytes72024101810.210 Why?
Gastroenteritis120042370.210 Why?
Xenograft Model Antitumor Assays9202435840.210 Why?
Adrenergic Agents12022740.200 Why?
Cell Culture Techniques3201916640.200 Why?
CD8-Positive T-Lymphocytes5202345500.200 Why?
5'-Nucleotidase120221610.190 Why?
Receptor, Notch212021870.190 Why?
Core Binding Factor Alpha 1 Subunit120211580.190 Why?
Inflammation32020107560.180 Why?
T-Lymphocytes, Cytotoxic2201817650.180 Why?
Cell Transformation, Neoplastic4202428280.180 Why?
Mesothelioma220168070.180 Why?
Eosinophilia120045590.170 Why?
Gene Amplification2202210850.170 Why?
Interferon Regulatory Factor-3220181410.170 Why?
SOXB1 Transcription Factors120212860.170 Why?
Coculture Techniques2202013420.170 Why?
Immune Evasion120233620.160 Why?
Ligands3202232760.160 Why?
Immunity320229980.160 Why?
Adenosine Deaminase120212510.160 Why?
Up-Regulation3202441220.160 Why?
Y-Box-Binding Protein 112018410.160 Why?
Transcription Factors72023121030.160 Why?
Receptor, Notch1120214950.160 Why?
Epigenomics120249360.160 Why?
Ligases120203320.160 Why?
Adaptor Proteins, Signal Transducing2202028950.160 Why?
MAP Kinase Kinase Kinase 112018560.160 Why?
Janus Kinase 1120181070.150 Why?
Cell Cycle3200429340.150 Why?
Von Hippel-Lindau Tumor Suppressor Protein120203070.150 Why?
p120 GTPase Activating Protein12018360.150 Why?
Lab-On-A-Chip Devices220224320.150 Why?
RNA, Antisense120181360.150 Why?
Apoptosis7202395010.150 Why?
Brain Neoplasms2202289860.150 Why?
rab GTP-Binding Proteins120192510.150 Why?
Flow Cytometry3201758700.150 Why?
AMP-Activated Protein Kinases220186000.150 Why?
Genomics6202357940.140 Why?
Hydroxamic Acids220174820.140 Why?
STAT1 Transcription Factor120183330.140 Why?
Carcinoma, Pancreatic Ductal2201817240.140 Why?
Anti-Bacterial Agents1201574080.140 Why?
Time-Lapse Imaging120171930.140 Why?
Chemokine CCL2120196050.140 Why?
Telomerase120217460.130 Why?
Neoplasm Metastasis2201849020.130 Why?
Mice, Nude2202336070.130 Why?
Microsatellite Repeats120187860.130 Why?
Drug Screening Assays, Antitumor120187170.130 Why?
Octamer Transcription Factor-112015300.130 Why?
Oxo-Acid-Lyases12015220.130 Why?
Tumor Escape120183700.130 Why?
Cancer Vaccines1202310460.130 Why?
Mitogen-Activated Protein Kinase Kinases120186420.130 Why?
RNA-Binding Proteins2202218940.130 Why?
Pancreatic Neoplasms3201853510.130 Why?
Genes, Tumor Suppressor1202010550.130 Why?
Leukemia, Hairy Cell12015820.120 Why?
Receptor, Fibroblast Growth Factor, Type 412014170.120 Why?
High-Throughput Screening Assays220189440.120 Why?
Disease Models, Animal52021181370.120 Why?
RNA, Double-Stranded320212950.120 Why?
Janus Kinase 2120185420.120 Why?
Histone Deacetylase Inhibitors220177720.120 Why?
Monocytes1202425750.120 Why?
Neovascularization, Physiologic1202213360.120 Why?
HEK293 Cells3201942640.120 Why?
Point Mutation1202015940.120 Why?
Neuroblastoma1202212520.120 Why?
Thoracic Neoplasms120162660.110 Why?
raf Kinases120141180.110 Why?
RNA Splice Sites120152110.110 Why?
Drug Resistance1202016170.110 Why?
Off-Label Use120151840.110 Why?
Gene Expression Profiling6201994110.110 Why?
Receptor, Fibroblast Growth Factor, Type 1120142560.110 Why?
Proto-Oncogene Proteins c-akt2201424480.110 Why?
Neutrophil Infiltration120163930.110 Why?
Receptor, Fibroblast Growth Factor, Type 2120142110.110 Why?
I-kappa B Proteins120142120.110 Why?
NIH 3T3 Cells320186700.110 Why?
Proto-Oncogene Proteins c-myc120189950.110 Why?
Benzimidazoles120188580.110 Why?
Diplopia120142150.100 Why?
Hemianopsia120141210.100 Why?
Protein Kinases1202016120.100 Why?
Immunophenotyping1201718710.100 Why?
Tamoxifen120179630.100 Why?
Phosphatidylinositol 3-Kinases2201428640.100 Why?
Skin Neoplasms2202357990.100 Why?
Chromosomes, Human, Pair 3120133150.100 Why?
Cell Proliferation82020104460.100 Why?
Treatment Failure1201826480.100 Why?
Lupus Erythematosus, Systemic1200421590.100 Why?
Gait Disorders, Neurologic120142380.100 Why?
Testicular Hormones220031880.100 Why?
Hematologic Neoplasms1202318950.100 Why?
Pleural Neoplasms120166090.100 Why?
Myeloid-Lymphoid Leukemia Protein120143010.100 Why?
Breast Neoplasms62023210250.090 Why?
Microfluidic Analytical Techniques120178060.090 Why?
Esophageal Neoplasms1202116480.090 Why?
Leukemia, Myeloid, Acute2201836020.090 Why?
Mutagenesis, Site-Directed3202016930.090 Why?
Insulin-Like Growth Factor I1201819280.090 Why?
Intracellular Signaling Peptides and Proteins3202328730.090 Why?
DNA Replication3200414120.090 Why?
Ubiquitin-Protein Ligases1202018890.090 Why?
Mice, Transgenic2202395300.090 Why?
Molecular Dynamics Simulation120134350.090 Why?
Chromosome Mapping2201646250.090 Why?
Proto-Oncogene Proteins c-rel12009710.090 Why?
DNA1200472330.090 Why?
Prostatic Neoplasms22024113450.080 Why?
NF-E2-Related Factor 2220233760.080 Why?
Ovarian Neoplasms3202448780.080 Why?
Fatal Outcome1201418320.080 Why?
Receptor, erbB-21202025540.080 Why?
Genes, Lethal120092250.080 Why?
Genome-Wide Association Study22020126260.080 Why?
Neoplastic Stem Cells1201713470.080 Why?
Nuclear Proteins5202357910.080 Why?
Male1920243597440.080 Why?
Immunologic Factors1201815880.080 Why?
Female2620243912700.080 Why?
Fibroblasts4202140900.080 Why?
Ubiquitination1201310080.080 Why?
Antigen Presentation2202312540.080 Why?
bcl-X Protein120094130.070 Why?
Enzyme Inhibitors2201437260.070 Why?
Membrane Transport Proteins1201310350.070 Why?
S Phase320044220.070 Why?
Immune Tolerance1201622990.070 Why?
Glioblastoma1202234840.070 Why?
Aged, 80 and over52021589950.070 Why?
Cyclin-Dependent Kinases320146560.070 Why?
Lymphocytes, Tumor-Infiltrating3201710880.070 Why?
Lymphocyte Activation1201754960.070 Why?
Oncogenes2201012200.070 Why?
Sequence Analysis, DNA2201447130.070 Why?
Cell Cycle Proteins4202034460.070 Why?
Cell Nucleolus220041560.070 Why?
Histone Deacetylases320177180.070 Why?
Lamin Type A220041870.060 Why?
Organoids220237290.060 Why?
DEAD-box RNA Helicases220233830.060 Why?
Acute Disease1201672690.060 Why?
Mice, Inbred C57BL62019220230.060 Why?
Middle Aged1020212203520.060 Why?
Neoplasm Invasiveness1201336180.060 Why?
Mice, Inbred NOD2202018370.060 Why?
RNA, Small Interfering4201834420.060 Why?
Glycoproteins2200322080.060 Why?
Neoplasm Recurrence, Local2201992760.060 Why?
Cell Lineage2202425330.060 Why?
Immunohistochemistry12017110710.060 Why?
Prognosis32023296580.060 Why?
Mitochondria1201736000.060 Why?
DNA Polymerase III12004510.060 Why?
Electronic Health Records1202147750.060 Why?
Eukaryotic Initiation Factor-4F12023420.050 Why?
Antibodies, Antinuclear120043440.050 Why?
Proliferating Cell Nuclear Antigen120042830.050 Why?
Mice, Knockout42020143720.050 Why?
Vaccines, Subunit120231610.050 Why?
Tumor Necrosis Factors120231060.050 Why?
Piperazines2201925250.050 Why?
Proteomics3202338170.050 Why?
GPI-Linked Proteins120244680.050 Why?
Proto-Oncogene Proteins c-kit120067270.050 Why?
Lymph Nodes1201434860.050 Why?
Proteins3200360290.050 Why?
Mutation, Missense2201425660.050 Why?
Gene Expression1201575880.050 Why?
Immunoblotting2201716490.050 Why?
Laparotomy120044650.050 Why?
STAT Transcription Factors120231880.050 Why?
Adaptor Proteins, Vesicular Transport120033060.050 Why?
Chemokine CXCL10120233160.050 Why?
Histones2200425830.050 Why?
Cysteine Endopeptidases120045480.050 Why?
Rubidium120001220.050 Why?
Cyclin-Dependent Kinase Inhibitor p16220216980.050 Why?
Smoking1201890730.050 Why?
Cohort Studies22021413350.050 Why?
Multienzyme Complexes120046660.050 Why?
MAP Kinase Signaling System2201814840.050 Why?
Polymorphism, Single Nucleotide22020157890.050 Why?
Cell Differentiation42024114810.050 Why?
Interphase120012280.050 Why?
CDC2-CDC28 Kinases120001100.040 Why?
History, 21st Century1200615750.040 Why?
Cyclin E120001550.040 Why?
Cytotoxicity, Immunologic1202313510.040 Why?
Prednisone1200415650.040 Why?
Protein Binding3202193350.040 Why?
Caspases120238780.040 Why?
Cell Count1200418350.040 Why?
Histone Demethylases120223230.040 Why?
PTEN Phosphohydrolase2201911150.040 Why?
Growth Inhibitors120003780.040 Why?
Mast Cells1200613900.040 Why?
Aged720211691520.040 Why?
Pulmonary Disease, Chronic Obstructive1201432240.040 Why?
Virus Internalization120234940.040 Why?
Transfection3202157810.040 Why?
Crystallography, X-Ray2201419820.040 Why?
3' Untranslated Regions120215140.040 Why?
Genome, Human3202144170.040 Why?
Luciferases, Firefly12018370.040 Why?
Germ Cells120236350.040 Why?
Calcium-Binding Proteins1202310670.040 Why?
Diagnosis, Differential12014129650.040 Why?
Positron-Emission Tomography1201564650.040 Why?
BRCA1 Protein1200511470.040 Why?
History, 20th Century1200627730.040 Why?
Intestine, Small1200412070.040 Why?
Alleles1200968980.040 Why?
T Cell Transcription Factor 112018670.040 Why?
Introns120219780.040 Why?
Kruppel-Like Transcription Factors120215030.040 Why?
Cell Division2200344630.040 Why?
Apoptosis Regulatory Proteins1202311350.040 Why?
Antibodies, Monoclonal1201591850.040 Why?
Cell Line52004156200.040 Why?
Phosphorylation2201983130.040 Why?
Drug Discovery2202010570.040 Why?
Binding Sites3201460480.040 Why?
DNA Helicases120238540.040 Why?
Immunologic Memory1202413540.040 Why?
Mitochondrial Proteins120239790.040 Why?
Cell Adhesion Molecules1202316020.040 Why?
Treatment Outcome32019650170.030 Why?
Phthalazines120193830.030 Why?
Proto-Oncogene Proteins c-bcl-21202314070.030 Why?
Cisplatin1202316440.030 Why?
HeLa Cells2202031050.030 Why?
Ovary120009580.030 Why?
Genome2201717390.030 Why?
Apyrase120183730.030 Why?
Antigens, Neoplasm1202419980.030 Why?
Acetoacetates12015190.030 Why?
Maximum Tolerated Dose120188770.030 Why?
Transforming Growth Factor beta1202319590.030 Why?
Antibodies1202424210.030 Why?
Receptor Protein-Tyrosine Kinases1202316130.030 Why?
Butyrates119961690.030 Why?
Serine120198300.030 Why?
Albumins120185750.030 Why?
Glucocorticoids1200421450.030 Why?
Amino Acid Sequence22020134510.030 Why?
Forkhead Transcription Factors1202216120.030 Why?
Computational Biology2201935050.030 Why?
Mice, SCID1202026270.030 Why?
Chromatin2200429380.030 Why?
Quinolines120207590.030 Why?
Enhancer Elements, Genetic1202113560.030 Why?
Interferon-gamma1202331570.030 Why?
Retinoblastoma-Like Protein p10722004710.030 Why?
Tissue Distribution1201822620.030 Why?
TOR Serine-Threonine Kinases1202320580.030 Why?
Genes, Neoplasm120163700.030 Why?
Protein-Tyrosine Kinases1202324180.030 Why?
Deoxycytidine120188730.030 Why?
Receptors, Immunologic1202014110.030 Why?
Algorithms12014139810.030 Why?
Transcription, Genetic2202075930.030 Why?
Adenosine Triphosphate1202019930.030 Why?
Drug Synergism1201717540.030 Why?
STAT3 Transcription Factor120178770.030 Why?
Retinoblastoma-Like Protein p13022003730.030 Why?
Vascular Endothelial Growth Factor A1202334840.030 Why?
Laparoscopy1200421470.030 Why?
Cell Movement1202452060.030 Why?
Mammary Glands, Human120132030.020 Why?
Tomography, X-Ray Computed12015205090.020 Why?
Repressor Proteins1202229810.020 Why?
Down-Regulation1201829130.020 Why?
Biopsy, Fine-Needle1201611100.020 Why?
Transduction, Genetic120148970.020 Why?
Molecular Sequence Data22014176240.020 Why?
Epigenesis, Genetic1202437580.020 Why?
Vaccination1202333610.020 Why?
3T3 Cells2200410850.020 Why?
Paclitaxel1201817360.020 Why?
Breast1201919630.020 Why?
Soft Tissue Neoplasms1201911520.020 Why?
Models, Genetic1202034420.020 Why?
DNA Methylation1202443730.020 Why?
Metabolome120179820.020 Why?
Amino Acid Substitution1201417370.020 Why?
Nervous System Neoplasms12010910.020 Why?
Base Sequence12021124460.020 Why?
Anti-Mullerian Hormone220034070.020 Why?
Mice, Inbred BALB C1201862160.020 Why?
Models, Molecular1202054340.020 Why?
Gene Expression Regulation22005119030.020 Why?
Ribosomal Protein S6 Kinases, 70-kDa120091010.020 Why?
Fatty Acids1201718040.020 Why?
Structure-Activity Relationship1201430840.020 Why?
Antineoplastic Agents, Hormonal1201715290.020 Why?
Cells, Cultured22021189570.020 Why?
Oligonucleotide Array Sequence Analysis1201737750.020 Why?
Statistics, Nonparametric1201428520.020 Why?
Epithelial Cells1202036630.020 Why?
Epithelial-Mesenchymal Transition120137300.020 Why?
Phenotype22022165460.020 Why?
Antigens, CD1201840000.020 Why?
Protein Multimerization120139830.020 Why?
Carrier Proteins1200149380.020 Why?
Polymerase Chain Reaction1201760680.020 Why?
Databases, Genetic1201417380.020 Why?
Reverse Transcriptase Polymerase Chain Reaction1201445730.020 Why?
Genetic Predisposition to Disease22020177900.020 Why?
Oncogene Proteins, Fusion1201415960.020 Why?
Protein Structure, Tertiary1201338000.020 Why?
Class I Phosphatidylinositol 3-Kinases120098950.020 Why?
Pharmacogenetics120086800.010 Why?
DNA Copy Number Variations1201320130.010 Why?
Head and Neck Neoplasms1201828820.010 Why?
DNA-Binding Proteins1200195850.010 Why?
Adult320212199940.010 Why?
Reproducibility of Results12021200800.010 Why?
Mullerian Ducts120032010.010 Why?
Active Transport, Cell Nucleus120044350.010 Why?
Cell Line, Transformed120038690.010 Why?
COS Cells1200311290.010 Why?
Sin3 Histone Deacetylase and Corepressor Complex12001200.010 Why?
E2F4 Transcription Factor12001320.010 Why?
Retinoblastoma-Binding Protein 1120011380.010 Why?
Transcription Factor DP1120011360.010 Why?
Lamins12000370.010 Why?
Massachusetts1201488030.010 Why?
Disease Progression12018135020.010 Why?
Biological Transport, Active120013270.010 Why?
E2F Transcription Factors120012690.010 Why?
Mi-2 Nucleosome Remodeling and Deacetylase Complex120011140.010 Why?
Cyclin-Dependent Kinase 2120001830.010 Why?
Culture Techniques120005300.010 Why?
Cervix Uteri120035820.010 Why?
Calmodulin-Binding Proteins120002320.010 Why?
G1 Phase120004030.010 Why?
Macromolecular Substances1200114330.010 Why?
Proteasome Endopeptidase Complex1200413130.010 Why?
Butyric Acid11996510.010 Why?
Follow-Up Studies12018392610.010 Why?
Antigens, Viral, Tumor119961530.010 Why?
Blotting, Western1200350390.010 Why?
Blood Proteins1200011730.010 Why?
Young Adult12021587410.010 Why?
In Situ Hybridization, Fluorescence1200025060.010 Why?
Prospective Studies12018543030.010 Why?
Microscopy, Fluorescence1200026510.010 Why?
Recombinant Fusion Proteins1200137350.010 Why?
Uterine Cervical Neoplasms1200320030.010 Why?
Risk Factors12018743590.010 Why?
Telomere119969330.010 Why?
Rats12003237110.000 Why?
Models, Biological1200194670.000 Why?
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.