Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David Allen Barbie, M.D.

Concepts (439)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Lung Neoplasms332023131042.370 Why?
Proto-Oncogene Proteins p21(ras)13202316922.010 Why?
Small Cell Lung Carcinoma720233881.500 Why?
ras Proteins5201610601.420 Why?
Carcinoma, Non-Small-Cell Lung12202352231.350 Why?
Spheroids, Cellular620233511.210 Why?
Protein Kinase Inhibitors17202355341.050 Why?
Cell Line, Tumor412023166900.970 Why?
Benzamides7201813790.960 Why?
Nucleotides, Cyclic22020810.880 Why?
Signal Transduction202021234040.750 Why?
Neoplasm Proteins4202137070.740 Why?
Neoplasms232023216960.730 Why?
Interferons420217060.710 Why?
Membrane Proteins5202278820.680 Why?
Killer Cells, Natural4202321330.680 Why?
Pyrimidines8201829430.680 Why?
Drug Resistance, Neoplasm15202351720.670 Why?
Endogenous Retroviruses220211120.640 Why?
Neoplasms, Experimental3202112760.620 Why?
Nasopharyngeal Neoplasms120192860.580 Why?
Platinum120182330.580 Why?
Pyrimidinones120183700.540 Why?
Proto-Oncogene Proteins c-met220225780.540 Why?
Adenocarcinoma4201863640.520 Why?
Janus Kinase 312015780.510 Why?
Retinoblastoma Protein920197050.510 Why?
Immunity, Innate4202129620.510 Why?
Mutation252023297860.500 Why?
Antineoplastic Agents112021136930.500 Why?
Principal Component Analysis120179400.490 Why?
Genes, ras320226900.490 Why?
Gene Deletion4202027510.480 Why?
Molecular Targeted Therapy5202127250.480 Why?
Doxycycline120153260.470 Why?
Autophagy3201612970.460 Why?
Immunotherapy8202344460.460 Why?
Pyridones120187110.460 Why?
Immunotherapy, Adoptive1202212710.460 Why?
I-kappa B Kinase420192520.450 Why?
Autocrine Communication120141710.440 Why?
MAP Kinase Kinase 1420203350.430 Why?
Antineoplastic Combined Chemotherapy Protocols102020115250.410 Why?
Mice392024812010.410 Why?
Tumor Microenvironment9202335900.400 Why?
Cell Survival5202058820.390 Why?
Animals4920241687680.390 Why?
Neovascularization, Pathologic2202226380.380 Why?
Single-Cell Analysis1202121820.370 Why?
Cyclin-Dependent Kinase 6320183230.360 Why?
Chemokine CCL5320162090.360 Why?
Proto-Oncogene Proteins B-raf2201720430.360 Why?
Melanoma5202355110.350 Why?
Oncogene Protein p21(ras)12009820.350 Why?
Gene Expression Regulation, Neoplastic10202184320.350 Why?
Endothelial Cells3202334860.350 Why?
Pancreatitis1201610920.330 Why?
Carcinoma, Renal Cell2202431430.330 Why?
Cell Nucleus6200529690.330 Why?
Cytokines8202373230.330 Why?
Humans9620247443660.320 Why?
Kidney Neoplasms2202442620.300 Why?
MicroRNAs2202137510.290 Why?
Proto-Oncogene Proteins3201445540.280 Why?
Microfluidics220226620.280 Why?
Interleukin-64201732030.270 Why?
Drug Design3202110760.260 Why?
Mastocytosis, Systemic120061000.250 Why?
Cyclin-Dependent Kinase 4220185390.250 Why?
Pyrazoles1201519720.240 Why?
Tumor Suppressor Protein p535202129490.240 Why?
Tumor Cells, Cultured7202063130.240 Why?
NF-kappa B3202324990.240 Why?
RNA Interference4201828900.240 Why?
Enzyme Activation4201637020.230 Why?
Carbonic Anhydrases120241150.230 Why?
Janus Kinases320232440.230 Why?
Pyridines1201528250.220 Why?
Butyrate Response Factor 112022100.220 Why?
Tumor Suppressor Proteins2202128500.220 Why?
T-Lymphocytes72024101830.220 Why?
Gastroenteritis120042450.210 Why?
Adrenergic Agents12022700.210 Why?
Cell Culture Techniques3201916780.210 Why?
CD8-Positive T-Lymphocytes5202344790.210 Why?
5'-Nucleotidase120221600.200 Why?
Receptor, Notch212021890.200 Why?
Core Binding Factor Alpha 1 Subunit120211640.190 Why?
Inflammation32020106370.190 Why?
T-Lymphocytes, Cytotoxic2201818210.180 Why?
Interferon Regulatory Factor-3220181230.180 Why?
Mesothelioma220168180.180 Why?
Eosinophilia120045410.180 Why?
Gene Amplification2202210630.180 Why?
SOXB1 Transcription Factors120212840.170 Why?
Coculture Techniques2202013410.170 Why?
Immune Evasion120233600.170 Why?
Adenosine Deaminase120212410.170 Why?
Ligands3202232820.170 Why?
Y-Box-Binding Protein 112018400.170 Why?
Immunity3202210140.170 Why?
Transcription Factors72023122070.160 Why?
Receptor, Notch1120215020.160 Why?
Ligases120203330.160 Why?
MAP Kinase Kinase Kinase 112018580.160 Why?
Adaptor Proteins, Signal Transducing2202029170.160 Why?
Von Hippel-Lindau Tumor Suppressor Protein120202900.160 Why?
Janus Kinase 1120181040.160 Why?
p120 GTPase Activating Protein12018390.160 Why?
Cell Cycle3200429670.160 Why?
Brain Neoplasms2202288610.160 Why?
RNA, Antisense120181380.160 Why?
Lab-On-A-Chip Devices220224280.160 Why?
rab GTP-Binding Proteins120192460.150 Why?
Apoptosis7202397240.150 Why?
AMP-Activated Protein Kinases220186100.150 Why?
Flow Cytometry3201759740.150 Why?
Microvessels120225440.150 Why?
Cell Transformation, Neoplastic3202129430.150 Why?
STAT1 Transcription Factor120183200.150 Why?
Genomics6202357170.150 Why?
Xenograft Model Antitumor Assays7202035540.150 Why?
Hydroxamic Acids220174940.150 Why?
Carcinoma, Pancreatic Ductal2201816360.150 Why?
Anti-Bacterial Agents1201571820.150 Why?
Time-Lapse Imaging120171950.140 Why?
Chemokine CCL2120196190.140 Why?
Telomerase120217300.140 Why?
Neoplasm Metastasis2201848510.140 Why?
Microsatellite Repeats120188020.140 Why?
Mice, Nude2202336890.130 Why?
Octamer Transcription Factor-112015310.130 Why?
Drug Screening Assays, Antitumor120187300.130 Why?
Oxo-Acid-Lyases12015220.130 Why?
Tumor Escape120183500.130 Why?
Cancer Vaccines1202310230.130 Why?
Pancreatic Neoplasms3201852630.130 Why?
Mitogen-Activated Protein Kinase Kinases120186470.130 Why?
Disease Models, Animal52021180340.130 Why?
RNA-Binding Proteins2202219030.130 Why?
Genes, Tumor Suppressor1202010970.130 Why?
Leukemia, Hairy Cell12015820.130 Why?
Receptor, Fibroblast Growth Factor, Type 412014170.130 Why?
Janus Kinase 2120185280.130 Why?
RNA, Double-Stranded320212900.130 Why?
High-Throughput Screening Assays220189440.130 Why?
Histone Deacetylase Inhibitors220177890.130 Why?
Neovascularization, Physiologic1202213510.120 Why?
HEK293 Cells3201942080.120 Why?
Neuroblastoma1202212260.120 Why?
Point Mutation1202016240.120 Why?
raf Kinases120141220.120 Why?
Thoracic Neoplasms120162680.120 Why?
Phosphoproteins2201824410.120 Why?
RNA Splice Sites120152090.120 Why?
Off-Label Use120151690.120 Why?
Drug Resistance1202016080.120 Why?
Receptor, Fibroblast Growth Factor, Type 2120141880.110 Why?
Neutrophil Infiltration120163910.110 Why?
Receptor, Fibroblast Growth Factor, Type 1120142500.110 Why?
Proto-Oncogene Proteins c-akt2201425040.110 Why?
Gene Expression Profiling6201994450.110 Why?
I-kappa B Proteins120142250.110 Why?
NIH 3T3 Cells320186770.110 Why?
Proto-Oncogene Proteins c-myc120189880.110 Why?
Diplopia120142000.110 Why?
Benzimidazoles120188500.110 Why?
Hemianopsia120141220.110 Why?
Immunophenotyping1201718800.110 Why?
Protein Kinases1202016400.110 Why?
Tamoxifen120179810.110 Why?
Skin Neoplasms2202356920.110 Why?
Chromosomes, Human, Pair 3120133230.110 Why?
Treatment Failure1201826180.110 Why?
Cell Proliferation82020104830.100 Why?
Phosphatidylinositol 3-Kinases2201429380.100 Why?
Lupus Erythematosus, Systemic1200421040.100 Why?
Testicular Hormones220031880.100 Why?
Gait Disorders, Neurologic120142310.100 Why?
Hematologic Neoplasms1202318320.100 Why?
Pleural Neoplasms120166070.100 Why?
Myeloid-Lymphoid Leukemia Protein120142940.100 Why?
Breast Neoplasms62023208240.100 Why?
Esophageal Neoplasms1202115850.100 Why?
Microfluidic Analytical Techniques120178280.090 Why?
Leukemia, Myeloid, Acute2201835240.090 Why?
DNA Replication3200413990.090 Why?
Mutagenesis, Site-Directed3202017230.090 Why?
Ubiquitin-Protein Ligases1202018620.090 Why?
Insulin-Like Growth Factor I1201820160.090 Why?
Intracellular Signaling Peptides and Proteins3202329160.090 Why?
Molecular Dynamics Simulation120134090.090 Why?
Mice, Transgenic2202397350.090 Why?
Proto-Oncogene Proteins c-rel12009710.090 Why?
Receptor, erbB-21202024170.090 Why?
Chromosome Mapping2201647400.090 Why?
DNA1200472940.090 Why?
NF-E2-Related Factor 2220233790.090 Why?
Fatal Outcome1201418510.090 Why?
Genome-Wide Association Study22020122620.090 Why?
Genes, Lethal120092420.080 Why?
Neoplastic Stem Cells1201713760.080 Why?
Nuclear Proteins5202358560.080 Why?
Immunologic Factors1201815800.080 Why?
Ubiquitination1201310120.080 Why?
Fibroblasts4202141620.080 Why?
bcl-X Protein120094110.080 Why?
Antigen Presentation2202312840.080 Why?
Male1720213501150.080 Why?
S Phase320044230.070 Why?
Immune Tolerance1201622590.070 Why?
Membrane Transport Proteins1201310310.070 Why?
Enzyme Inhibitors2201437990.070 Why?
Aged, 80 and over52021577760.070 Why?
Glioblastoma1202234810.070 Why?
Lymphocytes, Tumor-Infiltrating3201710380.070 Why?
Cyclin-Dependent Kinases320146710.070 Why?
Lymphocyte Activation1201755240.070 Why?
Oncogenes2201012650.070 Why?
Female2320233801930.070 Why?
Cell Cycle Proteins4202034640.070 Why?
Sequence Analysis, DNA2201448050.070 Why?
Organoids220237010.070 Why?
DEAD-box RNA Helicases220233750.070 Why?
Cell Nucleolus220041660.070 Why?
Lamin Type A220041900.070 Why?
Histone Deacetylases320177280.070 Why?
Mice, Inbred C57BL62019218330.070 Why?
Middle Aged1020212133900.070 Why?
Acute Disease1201671470.070 Why?
Neoplasm Invasiveness1201336160.060 Why?
RNA, Small Interfering4201835050.060 Why?
Mice, Inbred NOD2202018790.060 Why?
Neoplasm Recurrence, Local2201992400.060 Why?
Glycoproteins2200322660.060 Why?
Electronic Health Records1202144680.060 Why?
Mitochondria1201735140.060 Why?
Prognosis32023290600.060 Why?
Immunohistochemistry12017113660.060 Why?
DNA Polymerase III12004550.060 Why?
Eukaryotic Initiation Factor-4F12023410.060 Why?
Antibodies, Antinuclear120043260.060 Why?
Mice, Knockout42020145610.060 Why?
Proteomics3202336380.060 Why?
Proliferating Cell Nuclear Antigen120042850.060 Why?
Tumor Necrosis Factors120231090.050 Why?
Vaccines, Subunit120231680.050 Why?
Piperazines2201924880.050 Why?
Lymph Nodes1201434760.050 Why?
Proto-Oncogene Proteins c-kit120067760.050 Why?
Mutation, Missense2201425660.050 Why?
Proteins3200361000.050 Why?
STAT Transcription Factors120231820.050 Why?
Laparotomy120044730.050 Why?
Immunoblotting2201716830.050 Why?
Chemokine CXCL10120233050.050 Why?
Gene Expression1201577980.050 Why?
Adaptor Proteins, Vesicular Transport120033150.050 Why?
Histones2200425980.050 Why?
Cysteine Endopeptidases120045630.050 Why?
Rubidium120001330.050 Why?
Cyclin-Dependent Kinase Inhibitor p16220217050.050 Why?
Cohort Studies22021405590.050 Why?
Smoking1201889870.050 Why?
Polymorphism, Single Nucleotide22020155200.050 Why?
Interphase120012260.050 Why?
Multienzyme Complexes120046860.050 Why?
MAP Kinase Signaling System2201815250.050 Why?
CDC2-CDC28 Kinases120001130.050 Why?
History, 21st Century1200615340.050 Why?
Cyclin E120001720.040 Why?
Cytotoxicity, Immunologic1202313690.040 Why?
Prednisone1200415740.040 Why?
Protein Binding3202193840.040 Why?
Histone Demethylases120223210.040 Why?
Aged720211632880.040 Why?
Cell Count1200418560.040 Why?
Caspases120239280.040 Why?
Pulmonary Disease, Chronic Obstructive1201430470.040 Why?
PTEN Phosphohydrolase2201911420.040 Why?
Growth Inhibitors120003850.040 Why?
Positron-Emission Tomography1201562340.040 Why?
3' Untranslated Regions120215130.040 Why?
Mast Cells1200615440.040 Why?
Virus Internalization120235020.040 Why?
Crystallography, X-Ray2201420120.040 Why?
Transfection3202158950.040 Why?
Diagnosis, Differential12014129610.040 Why?
Germ Cells120236310.040 Why?
T Cell Transcription Factor 112018490.040 Why?
Genome, Human3202144200.040 Why?
Luciferases, Firefly12018460.040 Why?
Calcium-Binding Proteins1202310810.040 Why?
BRCA1 Protein1200511490.040 Why?
History, 20th Century1200627400.040 Why?
Receptors, CCR2120192120.040 Why?
Introns120219920.040 Why?
Alleles1200969330.040 Why?
Intestine, Small1200412400.040 Why?
Kruppel-Like Transcription Factors120215040.040 Why?
Cell Division2200345690.040 Why?
Apoptosis Regulatory Proteins1202311570.040 Why?
Up-Regulation2201942220.040 Why?
Antibodies, Monoclonal1201592740.040 Why?
Prostatic Neoplasms12021111260.040 Why?
Cell Line52004160000.040 Why?
Phosphorylation2201984360.040 Why?
Drug Discovery2202010580.040 Why?
DNA Helicases120238610.040 Why?
Binding Sites3201461110.040 Why?
Cell Adhesion Molecules1202316020.040 Why?
Mitochondrial Proteins120239940.040 Why?
Treatment Outcome32019631070.040 Why?
Phthalazines120193630.040 Why?
Cisplatin1202316620.040 Why?
Proto-Oncogene Proteins c-bcl-21202314340.030 Why?
HeLa Cells2202031300.030 Why?
Ovary120009810.030 Why?
Apyrase120183640.030 Why?
Maximum Tolerated Dose120188920.030 Why?
Antigens, Neoplasm1202419880.030 Why?
Acetoacetates12015220.030 Why?
Serine120198260.030 Why?
Butyrates119961630.030 Why?
Genome2201718070.030 Why?
Transforming Growth Factor beta1202320070.030 Why?
Antibodies1202424600.030 Why?
Albumins120185680.030 Why?
Receptor Protein-Tyrosine Kinases1202316600.030 Why?
Glucocorticoids1200421080.030 Why?
Forkhead Transcription Factors1202216130.030 Why?
Quinolines120207320.030 Why?
Computational Biology2201935190.030 Why?
Amino Acid Sequence22020138140.030 Why?
Chromatin2200429330.030 Why?
Enhancer Elements, Genetic1202113400.030 Why?
Mice, SCID1202027160.030 Why?
Retinoblastoma-Like Protein p10722004740.030 Why?
Interferon-gamma1202332070.030 Why?
Genes, Neoplasm120163760.030 Why?
Deoxycytidine120188260.030 Why?
Tissue Distribution1201823270.030 Why?
TOR Serine-Threonine Kinases1202321100.030 Why?
Protein-Tyrosine Kinases1202324550.030 Why?
Cell Differentiation32021114860.030 Why?
Receptors, Immunologic1202014230.030 Why?
Algorithms12014138820.030 Why?
Cell Lineage1202225040.030 Why?
Adenosine Triphosphate1202020270.030 Why?
Transcription, Genetic2202077210.030 Why?
STAT3 Transcription Factor120178740.030 Why?
Drug Synergism1201717940.030 Why?
Retinoblastoma-Like Protein p13022003760.030 Why?
Vascular Endothelial Growth Factor A1202335110.030 Why?
Laparoscopy1200421500.030 Why?
Tomography, X-Ray Computed12015201300.030 Why?
Mammary Glands, Human120131990.030 Why?
Biopsy, Fine-Needle1201610940.020 Why?
Down-Regulation1201830010.020 Why?
Repressor Proteins1202230240.020 Why?
Vaccination1202332790.020 Why?
Transduction, Genetic120149130.020 Why?
Paclitaxel1201817080.020 Why?
3T3 Cells2200411010.020 Why?
Molecular Sequence Data22014181110.020 Why?
Breast1201919700.020 Why?
Metabolome120178950.020 Why?
Models, Genetic1202034930.020 Why?
Nervous System Neoplasms12010910.020 Why?
Anti-Mullerian Hormone220034020.020 Why?
Amino Acid Substitution1201417930.020 Why?
Base Sequence12021127970.020 Why?
Soft Tissue Neoplasms1201913630.020 Why?
Models, Molecular1202054510.020 Why?
Mice, Inbred BALB C1201863860.020 Why?
Gene Expression Regulation22005120730.020 Why?
Ribosomal Protein S6 Kinases, 70-kDa120091040.020 Why?
Fatty Acids1201718090.020 Why?
Structure-Activity Relationship1201431300.020 Why?
Antineoplastic Agents, Hormonal1201715240.020 Why?
Cells, Cultured22021192330.020 Why?
Phenotype22022163670.020 Why?
Epithelial-Mesenchymal Transition120137130.020 Why?
Statistics, Nonparametric1201428870.020 Why?
Epithelial Cells1202036900.020 Why?
Oligonucleotide Array Sequence Analysis1201739210.020 Why?
Antigens, CD1201840260.020 Why?
Protein Multimerization120139710.020 Why?
Carrier Proteins1200150230.020 Why?
Polymerase Chain Reaction1201761710.020 Why?
Databases, Genetic1201417830.020 Why?
Genetic Predisposition to Disease22020174460.020 Why?
Reverse Transcriptase Polymerase Chain Reaction1201447510.020 Why?
Oncogene Proteins, Fusion1201415810.020 Why?
Protein Structure, Tertiary1201338480.020 Why?
Class I Phosphatidylinositol 3-Kinases120098900.020 Why?
DNA Copy Number Variations1201319410.020 Why?
Pharmacogenetics120086740.020 Why?
Head and Neck Neoplasms1201827360.020 Why?
Adult320212140520.010 Why?
DNA-Binding Proteins1200196470.010 Why?
Mullerian Ducts120031980.010 Why?
Reproducibility of Results12021199050.010 Why?
Active Transport, Cell Nucleus120044430.010 Why?
Cell Line, Transformed120038980.010 Why?
COS Cells1200311610.010 Why?
Sin3 Histone Deacetylase and Corepressor Complex12001190.010 Why?
E2F4 Transcription Factor12001360.010 Why?
Retinoblastoma-Binding Protein 1120011420.010 Why?
Transcription Factor DP1120011410.010 Why?
Ovarian Neoplasms2201348390.010 Why?
Disease Progression12018132860.010 Why?
Lamins12000360.010 Why?
Massachusetts1201486620.010 Why?
Biological Transport, Active120013490.010 Why?
E2F Transcription Factors120012770.010 Why?
Mi-2 Nucleosome Remodeling and Deacetylase Complex120011120.010 Why?
Cyclin-Dependent Kinase 2120001910.010 Why?
Culture Techniques120005540.010 Why?
Cervix Uteri120035900.010 Why?
Calmodulin-Binding Proteins120002500.010 Why?
G1 Phase120004150.010 Why?
Macromolecular Substances1200114540.010 Why?
Proteasome Endopeptidase Complex1200413350.010 Why?
Butyric Acid11996550.010 Why?
Follow-Up Studies12018390520.010 Why?
Antigens, Viral, Tumor119961560.010 Why?
Blotting, Western1200351810.010 Why?
Blood Proteins1200011240.010 Why?
Young Adult12021564290.010 Why?
In Situ Hybridization, Fluorescence1200026490.010 Why?
Prospective Studies12018532900.010 Why?
Microscopy, Fluorescence1200027000.010 Why?
Recombinant Fusion Proteins1200137730.010 Why?
Uterine Cervical Neoplasms1200320200.010 Why?
Risk Factors12018722960.010 Why?
Telomere119969100.010 Why?
Rats12003242520.000 Why?
Models, Biological1200195840.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.