Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Thomas Frederick McElrath, M.D., Ph.D.

Concepts (533)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Pre-Eclampsia46202412575.370 Why?
Phthalic Acids3420234834.770 Why?
Maternal Exposure39202410784.730 Why?
Environmental Pollutants34202412903.790 Why?
Premature Birth40202318163.790 Why?
Pregnancy2212024301793.080 Why?
Pregnancy Complications37202429693.060 Why?
Fetal Development1520247712.630 Why?
Vascular Endothelial Growth Factor Receptor-11420235602.570 Why?
Phenols2220245202.430 Why?
Pregnancy Trimester, First2420249182.420 Why?
Fetal Growth Retardation1520235851.950 Why?
Pregnancy Trimester, Second1520247381.900 Why?
Obstetric Labor, Premature1120202731.840 Why?
Gestational Age45202436151.710 Why?
Pregnancy Trimesters520191971.700 Why?
Pregnancy Proteins820152241.690 Why?
Birth Weight25202421171.670 Why?
Cell-Derived Microparticles320201611.660 Why?
Dinoprost1020241391.550 Why?
Fetal Membranes, Premature Rupture720231391.540 Why?
Pregnancy Trimester, Third1520235831.310 Why?
Infant, Newborn902024263941.180 Why?
Pregnancy Outcome28202429591.180 Why?
Oxidative Stress17202431451.160 Why?
Infant, Premature19201921241.040 Why?
Anticonvulsants7202219231.020 Why?
Benzhydryl Compounds1020189391.000 Why?
Placenta19202317240.970 Why?
Endocrine Disruptors1020242640.960 Why?
Delivery, Obstetric1320229530.950 Why?
Maternal-Fetal Exchange420214620.940 Why?
Glucose Intolerance420225790.900 Why?
Eclampsia22022600.880 Why?
Infant, Premature, Diseases720147120.860 Why?
Nifedipine120232200.860 Why?
Diabetes, Gestational9202212590.850 Why?
Female22620243969260.850 Why?
Fetal Macrosomia420221380.830 Why?
Cervix Uteri520205770.830 Why?
Case-Control Studies452024222860.820 Why?
Plasticizers52024520.820 Why?
Deoxyguanosine52018960.810 Why?
Placenta Previa120231260.740 Why?
Infant, Small for Gestational Age820224640.740 Why?
Fluorocarbons520245050.740 Why?
Epilepsy8202233240.740 Why?
Environmental Exposure12202445330.730 Why?
Adult14120242235280.710 Why?
Phenol32023440.690 Why?
Amniotic Fluid620123810.690 Why?
Flame Retardants42024970.680 Why?
Cesarean Section8202214140.670 Why?
Vitamin D12202333110.670 Why?
Pregnancy Complications, Infectious5202121810.670 Why?
Thyroid Hormones520244070.650 Why?
Placenta Accreta120232410.640 Why?
Postpartum Period5202411970.600 Why?
Humans23120247683690.590 Why?
Cerclage, Cervical42020320.570 Why?
Cervical Length Measurement12016460.530 Why?
Inflammation132024108630.530 Why?
Vitamin D Deficiency6202113890.530 Why?
Pregnancy-Associated Plasma Protein-A22014610.530 Why?
Prenatal Exposure Delayed Effects9202425380.520 Why?
Young Adult582024600380.520 Why?
Weight Gain5202323570.510 Why?
Body Mass Index162020130300.510 Why?
Reproductive Techniques, Assisted220185020.510 Why?
Thyroid Diseases220183880.500 Why?
Vitamins6202316380.500 Why?
Cytokines10202474400.490 Why?
Metals420197130.480 Why?
Twins220103400.470 Why?
Respiratory Distress Syndrome, Newborn320062390.470 Why?
Episiotomy32011210.460 Why?
Matrix Metalloproteinases420173940.460 Why?
Maternal Age720208090.450 Why?
Piracetam12014880.440 Why?
Uterine Cervical Incompetence22010240.440 Why?
Angiogenesis Inducing Agents220122540.440 Why?
Psychoses, Substance-Induced12014990.440 Why?
Prospective Studies362024549130.440 Why?
Fetal Viability22004230.430 Why?
Ultrasonography, Prenatal8202217670.430 Why?
Hysterectomy220188630.430 Why?
Prenatal Nutritional Physiological Phenomena120141610.430 Why?
Logistic Models232021133230.430 Why?
Obstetric Labor Complications520192430.430 Why?
Boston21202493590.420 Why?
Chorioamnionitis420111560.420 Why?
Blood Glucose7202464290.410 Why?
Oxylipins22024540.410 Why?
Interleukin-102202411840.400 Why?
Obesity132024130650.400 Why?
Estrogens, Non-Steroidal12012520.390 Why?
RNA1202227280.390 Why?
Magnesium Sulfate22020730.380 Why?
Odds Ratio18202296870.380 Why?
Pregnant Women720235760.380 Why?
Thyroid Gland1201811720.370 Why?
Dystocia12011340.370 Why?
Bronchopulmonary Dysplasia220163290.360 Why?
Linear Models10202258800.350 Why?
Pregnancy, Multiple220102160.340 Why?
Chemokines420209630.340 Why?
Hypertension5202386100.330 Why?
Birth Injuries120111510.330 Why?
Microcephaly220104260.330 Why?
Brachial Plexus120111730.320 Why?
Infant Mortality620197560.320 Why?
Urinary Tract Infections120158060.320 Why?
Placenta Diseases320121990.310 Why?
Birth Order22019950.310 Why?
Hypertension, Pregnancy-Induced420165200.310 Why?
Inflammation Mediators3201918920.310 Why?
Cerebral Palsy220124780.310 Why?
Abnormalities, Drug-Induced320193410.300 Why?
Eicosanoids220202840.300 Why?
Leukomalacia, Periventricular120091840.300 Why?
Systemic Inflammatory Response Syndrome120136200.300 Why?
Abortion, Spontaneous420245390.300 Why?
Multiple Sclerosis6202432450.290 Why?
Interleukin-62202432340.290 Why?
Progesterone220237490.290 Why?
Cohort Studies352024417820.290 Why?
Proteinuria120106130.280 Why?
Risk Factors362024749150.280 Why?
Mass Spectrometry3202022040.280 Why?
Puerperal Disorders220223030.280 Why?
Alkanesulfonic Acids320242030.280 Why?
Sensitivity and Specificity92022147250.270 Why?
Infant, Newborn, Diseases220225920.270 Why?
Cell Adhesion Molecules3201116150.260 Why?
Asthma6202362740.260 Why?
Parabens420191170.260 Why?
Glucose Tolerance Test5202411810.250 Why?
Dietary Supplements4202434450.240 Why?
Neovascularization, Physiologic4201913690.240 Why?
Multivariate Analysis82019120960.240 Why?
Creatinine1201019150.240 Why?
Fetal Organ Maturity22004830.230 Why?
F2-Isoprostanes12024350.230 Why?
Immunologic Factors2202416000.230 Why?
Fetus5202318830.230 Why?
Models, Theoretical1201635900.220 Why?
Chromatography, Liquid220199980.220 Why?
Rh-Hr Blood-Group System12023640.210 Why?
Alanine Transaminase220166050.210 Why?
Pulmonary Surfactants120041690.210 Why?
Tocolytic Agents12003240.210 Why?
Head320179270.210 Why?
Trophoblasts220182240.210 Why?
Perineum320172100.210 Why?
Estradiol3202019480.200 Why?
Esters420242120.200 Why?
Parity620169390.200 Why?
Metabolome2202010090.200 Why?
Blood Proteins3201311830.200 Why?
Depression2201982350.200 Why?
Blood Group Antigens120231850.190 Why?
Perinatology12002630.190 Why?
Enalapril120233160.190 Why?
Prenatal Care4202311590.190 Why?
Environmental Monitoring5201914640.190 Why?
Insulin-Like Growth Factor II220142680.190 Why?
Blood Pressure4202485370.190 Why?
ROC Curve3201636230.190 Why?
Albumins120045780.190 Why?
Micronutrients120243900.180 Why?
Obstetric Surgical Procedures12000310.180 Why?
Infant, Extremely Low Birth Weight22012840.180 Why?
Models, Statistical4201951030.180 Why?
Consumer Product Safety120211220.180 Why?
Trace Elements220191930.180 Why?
Thyroxine320186660.170 Why?
Chromatography, High Pressure Liquid2201615430.170 Why?
Cosmetics120211020.170 Why?
Fetal Blood6202313530.170 Why?
Infertility, Female220137640.170 Why?
Acidosis120212710.170 Why?
Hydatidiform Mole120222550.170 Why?
Analgesia, Epidural220193320.160 Why?
Male4520243647610.160 Why?
Laparoscopy3202020560.160 Why?
Placentation12019780.160 Why?
United States202024731200.160 Why?
Alpha-Globulins12019260.160 Why?
Proteinase Inhibitory Proteins, Secretory12019490.160 Why?
Factor XIII12019590.160 Why?
Paternal Exposure12019990.160 Why?
Phosphatidylcholine-Sterol O-Acyltransferase12019330.160 Why?
Estrone120202340.160 Why?
Pregnancy Complications, Cardiovascular220165180.160 Why?
Regression Analysis5201963530.160 Why?
Amine Oxidase (Copper-Containing)12018410.150 Why?
Angiogenic Proteins120181010.150 Why?
Preconception Care120191430.150 Why?
Carbanilides12018180.150 Why?
Reference Values7201849410.150 Why?
Predictive Value of Tests72022154590.150 Why?
Retrospective Studies172023818350.150 Why?
Benzophenones12018570.150 Why?
Analgesia, Obstetrical120191690.150 Why?
Isotretinoin120191340.150 Why?
Prolactin120206260.150 Why?
Infant, Very Low Birth Weight220164080.150 Why?
Labor Presentation12017550.140 Why?
Labor Stage, Second12017440.140 Why?
Brain Diseases2200315530.140 Why?
Thyroid Function Tests120182890.140 Why?
Magnesium120208160.140 Why?
Longitudinal Studies102020147660.130 Why?
Body Size120194630.130 Why?
Massachusetts8202389050.130 Why?
Risk Assessment102019243100.130 Why?
Cross-Sectional Studies92021263480.130 Why?
Tretinoin120195250.130 Why?
Tumor Necrosis Factor-alpha2202443620.130 Why?
Adolescent192023891630.130 Why?
Antioxidants1202416780.130 Why?
Likelihood Functions120199930.130 Why?
Suture Techniques120007760.130 Why?
Fatty Acids1202318180.120 Why?
Insurance Claim Review220187450.120 Why?
Incidence112020215520.120 Why?
Lead120218800.120 Why?
Area Under Curve1201916400.120 Why?
Live Birth120195160.120 Why?
Socioeconomic Factors6201978630.120 Why?
Infant152024364960.120 Why?
Asymptomatic Diseases120185910.120 Why?
Mongolia32020930.120 Why?
Product Surveillance, Postmarketing120194620.120 Why?
Healthcare Disparities1201034120.120 Why?
Risk4201796420.120 Why?
Proteomics2202039010.120 Why?
Infectious Disease Transmission, Vertical1202113590.120 Why?
Follow-Up Studies72019394290.120 Why?
Demography1201916430.120 Why?
Calcium-Binding Proteins1201910850.110 Why?
Blood Chemical Analysis120164360.110 Why?
Hazardous Substances120151530.110 Why?
Chorionic Gonadotropin, beta Subunit, Human12014840.110 Why?
Antihypertensive Agents1202320280.110 Why?
Interleukin-1beta1201910210.110 Why?
Breast Feeding1202213650.110 Why?
Prenatal Diagnosis3202312740.110 Why?
Thyrotropin120178340.110 Why?
Lung22004100900.110 Why?
Coitus120141340.110 Why?
Retinopathy of Prematurity220134490.110 Why?
C-Reactive Protein4202438540.110 Why?
Uterine Neoplasms1202214230.100 Why?
Time Factors62019402710.100 Why?
HELLP Syndrome12012410.100 Why?
Genomic Imprinting120143240.100 Why?
Brain Injury, Chronic12012680.100 Why?
Estrogens1201915310.100 Why?
Immunization1201612200.100 Why?
Fever1201916220.100 Why?
Smoking4201590990.100 Why?
Respiratory Sounds120167020.090 Why?
Organ Size1201622680.090 Why?
Hyperoxia120132610.090 Why?
Cholecalciferol120165570.090 Why?
Propensity Score1201819700.090 Why?
Proportional Hazards Models32019125610.090 Why?
Abortion, Habitual12010610.090 Why?
Decidua22022820.090 Why?
Heart Rate, Fetal12010760.080 Why?
Child Behavior Disorders120148130.080 Why?
Folic Acid3202313360.080 Why?
Air Pollution1202323640.080 Why?
Postnatal Care220142730.080 Why?
Particulate Matter1202126140.080 Why?
Probability2202224830.080 Why?
Reproductive History120102100.080 Why?
Bayes Theorem3202323590.080 Why?
Mental Recall1201512260.080 Why?
Cephalometry120103790.080 Why?
Urban Population1201620470.080 Why?
Puerto Rico220193810.080 Why?
Fetal Diseases120139130.070 Why?
Diabetes Mellitus, Type 12202034390.070 Why?
Attitude of Health Personnel1200239220.070 Why?
Vaccines120168450.070 Why?
Genetic Predisposition to Disease22020180470.070 Why?
Gonadal Steroid Hormones120117080.070 Why?
Labor, Obstetric220173230.070 Why?
Statistics, Nonparametric1201328610.070 Why?
Analysis of Variance1201662420.070 Why?
Child Development3202223280.070 Why?
Air Pollutants1202129050.070 Why?
Parturition220234530.070 Why?
Angiotensin II120108490.070 Why?
Fertilization in Vitro1201512970.070 Why?
Cerebral Ventricles120095510.070 Why?
Sleep Deprivation120148480.070 Why?
Comorbidity32021106010.070 Why?
Maternal-Child Health Centers12006420.070 Why?
Body Weight1201746300.070 Why?
Hemostasis, Surgical120071270.070 Why?
Uterus220186600.070 Why?
Middle Aged1220192234060.060 Why?
Immunosuppressive Agents1201942130.060 Why?
Bacteremia120139850.060 Why?
Triiodothyronine220184920.060 Why?
Rural Population1201623170.060 Why?
Morbidity2202117600.060 Why?
Sulfones220184480.060 Why?
Receptors, Cell Surface1201428180.060 Why?
Phenotype22020167120.060 Why?
Malpractice120105610.060 Why?
Steroids220189370.060 Why?
Factor V120051680.060 Why?
Diethylhexyl Phthalate22016840.060 Why?
Treatment Outcome52023654080.060 Why?
DNA1201872130.060 Why?
Isoprostanes12024210.060 Why?
Cluster Analysis1201127300.060 Why?
Blood Vessels1201011120.060 Why?
Antigens, CD1201440220.060 Why?
Stress, Psychological1201945380.060 Why?
Biomedical Research1201934630.060 Why?
Polypyrimidine Tract-Binding Protein12023220.060 Why?
Gene Expression Profiling1202095080.060 Why?
Fluorescence Polarization120041400.060 Why?
Pregnancy Complications, Hematologic120051820.060 Why?
Computational Biology1201635490.060 Why?
Research Design1201962170.050 Why?
Administration, Intravaginal120231490.050 Why?
Infant, Low Birth Weight120088750.050 Why?
Ultrasonography2200959940.050 Why?
Leptin1201115980.050 Why?
Anesthesia, Obstetrical120052350.050 Why?
Severity of Illness Index32021159650.050 Why?
Developmental Disabilities1201215160.050 Why?
Practice Guidelines as Topic3201674490.050 Why?
Feeding Behavior2201432020.050 Why?
Prognosis32021300310.050 Why?
Europe2202034390.050 Why?
Genome-Wide Association Study22020127710.050 Why?
Fetal Weight12022880.050 Why?
Polymorphism, Single Nucleotide22020160230.050 Why?
Arachidonic Acid120244290.050 Why?
Models, Biological1201895050.050 Why?
Double-Blind Method32024124500.050 Why?
Breast Neoplasms22020211570.050 Why?
Progestins120233020.050 Why?
Limit of Detection120222770.050 Why?
Nutritional Status2201916230.050 Why?
Beta Particles12021510.050 Why?
Fatty Acids, Unsaturated120245420.040 Why?
Point Mutation1200515960.040 Why?
Algorithms22016141570.040 Why?
Prevalence42019158790.040 Why?
Hospitalization22021108450.040 Why?
Extraction, Obstetrical12020280.040 Why?
Sphingomyelins120001050.040 Why?
Insulin Resistance2201639740.040 Why?
Lactation120223970.040 Why?
Phosphates120237670.040 Why?
Guidelines as Topic2201613950.040 Why?
Radiography, Interventional1200711280.040 Why?
Pilot Projects3202187300.040 Why?
Nervous System Diseases1201016680.040 Why?
Vasculitis120035240.040 Why?
MicroRNAs1201538060.040 Why?
Child, Preschool72019426200.040 Why?
Attention Deficit Disorder with Hyperactivity1201437420.040 Why?
Pregnancy, Unplanned12019860.040 Why?
Inflammatory Bowel Diseases1201324440.040 Why?
Nerve Block120057110.040 Why?
Maternal Mortality120213050.040 Why?
Nutritional Requirements120002790.040 Why?
Phosphatidylcholines120004060.040 Why?
Pregnancy in Adolescence120001660.040 Why?
Tetanus11998520.040 Why?
Diseases in Twins120004470.040 Why?
Oxygen1201042690.040 Why?
Michigan120193410.040 Why?
Naphthalenesulfonates12017170.040 Why?
Glycogen120182520.040 Why?
Registries3201983720.040 Why?
Tetanus Toxoid119981890.040 Why?
Immunity, Maternally-Acquired119981120.040 Why?
Cognition Disorders1201239840.040 Why?
Lipid Peroxidation120182760.040 Why?
Intracranial Hemorrhages120038150.040 Why?
Triclosan12018580.040 Why?
California1202114440.040 Why?
Substance-Related Disorders1201444530.040 Why?
Norway120185010.040 Why?
Matrix Metalloproteinase 1120171460.040 Why?
Receptors, Vascular Endothelial Growth Factor220116650.040 Why?
Cardiovascular Diseases22015156380.030 Why?
Anti-HIV Agents1201345630.030 Why?
Enterocolitis, Necrotizing120013270.030 Why?
Interferon-beta120193480.030 Why?
Hydrogen-Ion Concentration1202124880.030 Why?
Data Interpretation, Statistical2201827050.030 Why?
Israel120197260.030 Why?
Genotype22023130450.030 Why?
Lactic Acid1202111400.030 Why?
Patient Compliance1200626960.030 Why?
Pregnancy Rate120196550.030 Why?
Minority Groups1202312150.030 Why?
Cleft Lip120015130.030 Why?
Telomere120229420.030 Why?
Diabetes Mellitus1201458870.030 Why?
Nitrogen Dioxide120195270.030 Why?
Child62022808560.030 Why?
Parents2202335960.030 Why?
HIV-11201369090.030 Why?
False Negative Reactions120165750.030 Why?
DNA Methylation2202344250.030 Why?
Membrane Proteins1201278950.030 Why?
Research Support as Topic120196990.030 Why?
Aspartic Acid120175770.030 Why?
Carbon120186710.030 Why?
Blood Transfusion1202113080.030 Why?
Recurrence2201985100.030 Why?
Neurotransmitter Agents120186660.030 Why?
Nuclear Family120153110.030 Why?
Matrix Metalloproteinase 9120176350.030 Why?
Databases, Factual3201980810.030 Why?
Metabolic Networks and Pathways120187970.030 Why?
False Positive Reactions120169620.030 Why?
Hormones120188700.030 Why?
Veins120187670.030 Why?
Lymphatic Vessels120183580.030 Why?
Heart Defects, Congenital1201047130.030 Why?
Pregnancy, High-Risk120141210.030 Why?
Fluid Therapy120175850.030 Why?
Seasons1201915260.030 Why?
Calibration120168230.030 Why?
Arteries1201811260.030 Why?
Infertility120196540.030 Why?
Reproducibility of Results32016202320.030 Why?
Point-of-Care Systems1202112270.030 Why?
Adverse Drug Reaction Reporting Systems120164950.030 Why?
Sweden1201513820.030 Why?
Killer Cells, Natural1202222070.030 Why?
Diabetes Complications1201913220.030 Why?
Adiposity1202218880.020 Why?
Pyrroles1201711270.020 Why?
Adrenal Cortex Hormones1200018910.020 Why?
Fetal Monitoring12010700.020 Why?
Corticotropin-Releasing Hormone120113590.020 Why?
Spectrometry, Mass, Electrospray Ionization120112670.020 Why?
Age Factors22019184770.020 Why?
Botswana1201310590.020 Why?
Drug Prescriptions1201916770.020 Why?
Receptors, Cytokine120102570.020 Why?
Drug Therapy, Combination1201963200.020 Why?
Vascular Endothelial Growth Factor A2201135200.020 Why?
Observer Variation1201626220.020 Why?
Acute-Phase Proteins120102510.020 Why?
Mice, Knockout22018144830.020 Why?
Sepsis1200326020.020 Why?
Metabolomics1201816750.020 Why?
Cardiovascular Surgical Procedures120101930.020 Why?
Adrenal Glands120115570.020 Why?
Overweight1202024280.020 Why?
Computer Simulation1202262780.020 Why?
Lipids1201933460.020 Why?
Diet, Sodium-Restricted120102910.020 Why?
Aspirin1202031390.020 Why?
Survival Analysis12001101270.020 Why?
Patient Readmission1202233080.020 Why?
Catechol O-Methyltransferase120102510.020 Why?
Diagnostic and Statistical Manual of Mental Disorders1201419940.020 Why?
Systole120109380.020 Why?
Cross-Over Studies1201421030.020 Why?
Hospitals1202139060.020 Why?
Cell Hypoxia120106610.020 Why?
Peroxidase120106100.020 Why?
Data Collection1201633290.020 Why?
Multicenter Studies as Topic1201117270.020 Why?
Confidence Intervals1201229320.020 Why?
Mice32022820510.020 Why?
HIV Infections12013174920.020 Why?
Sodium, Dietary120104270.020 Why?
Alcohol Drinking1201940520.020 Why?
Secondary Prevention1201214790.020 Why?
Drug Synergism1201017650.020 Why?
Developing Countries1199829010.020 Why?
Milk, Human120104890.020 Why?
Infusions, Intravenous1201022280.020 Why?
Homeostasis1201633510.010 Why?
Feasibility Studies1201653080.010 Why?
Sodium1201015950.010 Why?
Antiretroviral Therapy, Highly Active1201318980.010 Why?
Vesicovaginal Fistula11964100.010 Why?
Viral Load1201333740.010 Why?
Postpartum Hemorrhage120072730.010 Why?
Cell Adhesion1201031030.010 Why?
Urinary Bladder Diseases119641670.010 Why?
Alleles1201468800.010 Why?
Catheterization1200714310.010 Why?
Animals320221694240.010 Why?
Pandemics1202187510.010 Why?
Clinical Competence1201648410.010 Why?
Iatrogenic Disease119645520.010 Why?
Obstetrical Forceps1199980.010 Why?
Liver1201675750.010 Why?
Vacuum Extraction, Obstetrical11999140.010 Why?
Health Care Surveys1200624370.010 Why?
Gene Expression Regulation, Developmental1201036120.010 Why?
Disease Models, Animal12018183900.010 Why?
Wounds and Injuries2199925180.010 Why?
Physicians1201646150.010 Why?
Heparin1200516360.010 Why?
Labor, Induced119991520.010 Why?
Cell Movement1201052230.010 Why?
Gene Expression Regulation12015119280.010 Why?
Immunization Schedule119982270.010 Why?
Congenital Abnormalities120017080.010 Why?
Venous Thrombosis1200513170.010 Why?
Bangladesh119987350.010 Why?
Injury Severity Score1199910530.010 Why?
Oxytocin119994020.010 Why?
Immunization Programs119982670.010 Why?
Poverty1200627190.010 Why?
Cells, Cultured12010190350.010 Why?
Brain12020274390.010 Why?
Diabetes Mellitus, Type 212016122420.010 Why?
Health Services Accessibility1200655080.000 Why?
Cause of Death1199837270.000 Why?
Magnetic Resonance Imaging12013368400.000 Why?
Survival Rate11998128750.000 Why?
Postoperative Complications11964158790.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.