Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jean J. Zhao, Ph.D.

Concepts (503)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Phosphatidylinositol 3-Kinases41202229384.650 Why?
PTEN Phosphohydrolase18202311423.180 Why?
Class I Phosphatidylinositol 3-Kinases2320218903.010 Why?
Cyclin-Dependent Kinase 4720225382.210 Why?
Cyclin-Dependent Kinase 6520223222.140 Why?
Class Ia Phosphatidylinositol 3-Kinase82021741.790 Why?
Phosphatidylinositol 3-Kinase520231301.740 Why?
Breast Neoplasms282023208221.370 Why?
Protein Kinase Inhibitors13202355351.310 Why?
Cell Transformation, Neoplastic14201829421.240 Why?
Mammary Neoplasms, Animal220231371.210 Why?
TOR Serine-Threonine Kinases8201821091.070 Why?
Neoplasms222022216831.010 Why?
Signal Transduction442023234031.000 Why?
Receptor, erbB-210202324160.960 Why?
Morpholines920195710.890 Why?
Protein Isoforms7202017300.870 Why?
Multiprotein Complexes4201811190.870 Why?
Hamartoma Syndrome, Multiple220131110.860 Why?
Mice702023811830.840 Why?
Aminopyridines720195420.810 Why?
Protein Biosynthesis3201821260.810 Why?
Drug Resistance, Neoplasm12202351720.810 Why?
Proto-Oncogene Proteins c-akt12202225030.780 Why?
Brain Neoplasms10202388630.780 Why?
Mammary Neoplasms, Experimental520235200.770 Why?
Cell Line, Tumor322023166890.770 Why?
Mitosis3202312080.760 Why?
Animals8520231687570.720 Why?
Ovarian Neoplasms5202348380.700 Why?
Cell Cycle7202329670.700 Why?
Immune Evasion120233600.700 Why?
Eukaryotic Initiation Factors22016920.690 Why?
Gene Expression Regulation, Neoplastic13202084280.690 Why?
Cell Proliferation172022104810.670 Why?
Antineoplastic Agents172022136950.670 Why?
RNA-Binding Proteins3201819030.660 Why?
BRCA1 Protein3202211490.640 Why?
Cyclin-Dependent Kinases320196710.640 Why?
Mammary Glands, Animal320172760.610 Why?
Hematopoiesis3201920720.600 Why?
ADP-Ribosylation Factor 112016430.570 Why?
Ribosomal Proteins120183600.550 Why?
Molecular Targeted Therapy4202227270.540 Why?
Receptor, trkB120161250.530 Why?
Isoenzymes5201517260.510 Why?
Adaptor Proteins, Signal Transducing5202029160.510 Why?
Small Molecule Libraries120207200.490 Why?
Leukemia, Myelomonocytic, Juvenile12014200.480 Why?
Epithelial Cells7201736900.460 Why?
Gene Expression Regulation, Enzymologic2201912130.450 Why?
Mammary Glands, Human220051990.440 Why?
Transcription, Genetic2201877220.440 Why?
Muscle Development120152710.440 Why?
Immunity1201810120.430 Why?
Phosphorylation11201984360.420 Why?
Genes, ras220146900.400 Why?
Antigens, Polyomavirus Transforming320072580.400 Why?
Oncogene Proteins320187490.400 Why?
Astrocytoma120167900.400 Why?
Mice, Nude10201836890.400 Why?
Immunotherapy3202344450.390 Why?
Polyomavirus220122480.380 Why?
Enzyme Inhibitors7201937980.370 Why?
Tumor Microenvironment6202335860.370 Why?
Carrier Proteins3201850210.370 Why?
Membrane Proteins6201878800.360 Why?
Glioblastoma3202034810.350 Why?
Anoikis12009490.350 Why?
Gene Dosage2201312520.350 Why?
Myeloproliferative Disorders120156060.340 Why?
Disease Models, Animal132019180290.340 Why?
Gene Expression Profiling6201894380.340 Why?
Apoptosis6202097270.330 Why?
Xenograft Model Antitumor Assays9202235570.330 Why?
Humans8820237443430.330 Why?
Astrocytes1201612700.330 Why?
RNA1201827490.320 Why?
Oncogene Proteins, Fusion1201615810.320 Why?
Pro-Opiomelanocortin320151630.320 Why?
Estrogen Receptor alpha320185770.320 Why?
Immunohistochemistry72019113660.310 Why?
Neoplasm Transplantation6201720850.310 Why?
Carcinoma, Non-Small-Cell Lung2202352210.300 Why?
Fibroblasts6201641610.300 Why?
Leukemia1201515110.290 Why?
Hematopoietic Stem Cells2201933860.290 Why?
Oncogene Protein v-akt420191350.280 Why?
Phthalazines320183630.280 Why?
Mice, Knockout132019145570.280 Why?
Cyclin-Dependent Kinase Inhibitor p16220227050.280 Why?
Glucose6202243970.280 Why?
Camptothecin320235760.270 Why?
Antineoplastic Combined Chemotherapy Protocols52018115240.270 Why?
Alternative Splicing3201811170.260 Why?
Mice, SCID4201627160.260 Why?
Membrane Glycoproteins1201637680.260 Why?
Female4520233801940.250 Why?
Enzyme Activation6201937010.250 Why?
Mice, Transgenic11201897340.250 Why?
Insulin2201065800.240 Why?
Endometrial Neoplasms1201313530.240 Why?
RNA, Messenger22018130330.240 Why?
Tumor Suppressor Protein p533200929480.230 Why?
Epigenesis, Genetic1201736470.230 Why?
Ventromedial Hypothalamic Nucleus22016480.230 Why?
Models, Biological7201895830.220 Why?
Proto-Oncogene Proteins p21(ras)3202216920.220 Why?
Tankyrases12022140.210 Why?
Cells, Cultured102021192290.210 Why?
Cell Line, Transformed220188980.210 Why?
Cyclic ADP-Ribose12021170.210 Why?
Armadillo Domain Proteins12021220.210 Why?
Leptin4201715990.210 Why?
Blood-Brain Barrier2201910170.210 Why?
Phosphatidylinositol Phosphates220152090.200 Why?
Lung Neoplasms32023131020.200 Why?
ras Proteins3201610600.200 Why?
Receptors, Estrogen1200921870.200 Why?
Blotting, Western5202051790.200 Why?
Mice, Inbred C57BL112022218270.190 Why?
Toll-Like Receptor 9120222120.190 Why?
Phosphoglycerate Dehydrogenase12020380.190 Why?
HEK293 Cells3202142040.190 Why?
Liver3201374740.180 Why?
High-Throughput Screening Assays220169440.180 Why?
rac1 GTP-Binding Protein220162370.180 Why?
Oligonucleotides, Antisense120224330.180 Why?
Blood Glucose2201562560.180 Why?
Tryptophan120224780.180 Why?
Mutation102023297860.180 Why?
Nucleic Acids120221820.170 Why?
Mutation, Missense4201525640.170 Why?
Muscle, Skeletal1201549310.170 Why?
Cell Cycle Proteins3202334620.170 Why?
DNA, Complementary2201820500.170 Why?
Thiazoles2201814830.170 Why?
Transcription Factor AP-1120203170.170 Why?
Phenylenediamines12019900.170 Why?
Reverse Transcription12018470.170 Why?
Gene Knockdown Techniques3202016550.170 Why?
Lipids1201033050.160 Why?
Alleles4201869330.160 Why?
Estrogens2201615660.160 Why?
Frameshift Mutation120203990.160 Why?
STAT3 Transcription Factor120238730.160 Why?
Gene Knockout Techniques320198090.160 Why?
Piperazines3201824880.160 Why?
Mice, Inbred NOD2201518780.160 Why?
Leukemia, Myeloid, Acute1201435230.160 Why?
Lactic Acid1202311330.150 Why?
Eukaryotic Initiation Factor-2120181900.150 Why?
Drug Design2201810760.150 Why?
Tumor Escape120203490.150 Why?
Nerve Degeneration120217480.150 Why?
DNA Damage2201824320.140 Why?
Cell Survival3201658820.140 Why?
Intercellular Signaling Peptides and Proteins2201716760.140 Why?
Receptors, Leptin120173600.140 Why?
Neurons6201793380.140 Why?
Peripheral Nervous System Diseases120216850.140 Why?
Autophagy2201613000.140 Why?
Cell Adhesion Molecules, Neuronal120172650.140 Why?
Cytoskeletal Proteins1202113640.140 Why?
RNA, Double-Stranded120172900.130 Why?
Proto-Oncogene Proteins2201045540.130 Why?
Protein Kinases3200916400.130 Why?
Membrane Microdomains120162030.130 Why?
Immunoconjugates120239010.130 Why?
Thyroid Hormones120183900.130 Why?
Cyclin C12014140.130 Why?
MAP Kinase Signaling System2201415260.130 Why?
rac GTP-Binding Proteins120151640.130 Why?
Peptide Library120163490.130 Why?
Glucose Intolerance220105770.130 Why?
Hypothalamus2201110630.130 Why?
Energy Metabolism5201728990.130 Why?
Neoplasms, Experimental1202012760.120 Why?
Insulin Resistance3201538640.120 Why?
Hypoxia-Inducible Factor 1, alpha Subunit120186270.120 Why?
Cancer Vaccines1202210230.120 Why?
Cell Line52015159970.120 Why?
Antigens, Viral, Tumor220121540.120 Why?
Paclitaxel1202117080.120 Why?
Ki-67 Antigen120166440.120 Why?
Caspase 3120167580.120 Why?
Homeostasis5201533400.120 Why?
Interferons120177060.120 Why?
Glucagon-Like Peptide 212013500.110 Why?
Viruses120173740.110 Why?
Axons1202116840.110 Why?
Uterus120187110.110 Why?
Myoblasts120152380.110 Why?
Histone Deacetylases120187280.110 Why?
Anticarcinogenic Agents120152530.110 Why?
Prodrugs120152680.110 Why?
Genes, erbB-2120131620.110 Why?
Biological Assay120166520.110 Why?
Conserved Sequence1201612020.110 Why?
MAP Kinase Kinase Kinases220122610.110 Why?
Histone Deacetylase Inhibitors120187890.110 Why?
Glioma2201834010.110 Why?
Prostatic Intraepithelial Neoplasia12012760.110 Why?
Chemotaxis120156070.110 Why?
Pyrimidinones120143710.110 Why?
Drug Evaluation, Preclinical1201813750.110 Why?
Receptor, erbB-3120131420.100 Why?
Proto-Oncogene Proteins c-myc220119870.100 Why?
Eating2201715360.100 Why?
Androgen Receptor Antagonists120121140.100 Why?
Genomic Instability120166950.100 Why?
Sequence Alignment1201622560.100 Why?
Antigen Presentation1201712840.100 Why?
Receptor, Notch1120145020.100 Why?
Lysine1201610070.100 Why?
Delayed-Action Preparations120159680.100 Why?
T-Lymphocytes, Cytotoxic1201818210.100 Why?
Repressor Proteins2201730230.100 Why?
Forkhead Transcription Factors3201416130.100 Why?
Antineoplastic Agents, Phytogenic120156240.100 Why?
Adaptation, Physiological1201813120.100 Why?
NF-kappa B2201824990.100 Why?
Immunologic Factors1202015800.100 Why?
Genotype22017129510.100 Why?
Drug Delivery Systems3201722190.090 Why?
Neuropeptides120169420.090 Why?
Hypertension, Pulmonary1202115370.090 Why?
Fibroblast Growth Factors120168790.090 Why?
Oligonucleotide Array Sequence Analysis2201739200.090 Why?
Remission Induction1201623860.090 Why?
Indazoles120122890.090 Why?
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma120144070.090 Why?
DNA Repair2201820460.090 Why?
Epidermis120135280.090 Why?
Pyrimidines2201929420.090 Why?
AMP-Activated Protein Kinases120136110.090 Why?
Mitogen-Activated Protein Kinases2201612850.090 Why?
Nanostructures120155510.090 Why?
Erythropoiesis120147050.090 Why?
Neoplastic Stem Cells1201813760.090 Why?
Tumor Burden2201319150.090 Why?
Protein Binding4201693860.080 Why?
Neoplasm Recurrence, Local2201992390.080 Why?
Bone Marrow2201929480.080 Why?
Gene Silencing2201715380.080 Why?
Sequence Analysis, DNA1202048030.080 Why?
Anti-Inflammatory Agents1201817900.080 Why?
Transplantation, Heterologous2201423820.080 Why?
Hedgehog Proteins120137830.080 Why?
Amino Acid Sequence32016138150.080 Why?
CD8-Positive T-Lymphocytes1202244790.080 Why?
Phosphotransferases120093080.080 Why?
Calcium1202157560.080 Why?
Rats42021242600.080 Why?
Neural Stem Cells120158510.080 Why?
Colonic Neoplasms1202025410.080 Why?
Tumor Suppressor Proteins2201628490.080 Why?
Kaplan-Meier Estimate1201965380.080 Why?
Drug Discovery1201610580.080 Why?
Neoadjuvant Therapy1201927280.080 Why?
Mesenchymal Stem Cells1201816320.080 Why?
Dendritic Cells1201827250.080 Why?
Proto-Oncogene Proteins c-met120115780.070 Why?
Phosphoproteins1201624400.070 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11220192340.070 Why?
RNA, Small Interfering1201635050.070 Why?
Polymorphism, Single Nucleotide22020155190.070 Why?
Neoplasms, Hormone-Dependent120094150.070 Why?
Male1820223501180.070 Why?
Cell Membrane1201637480.070 Why?
Myristic Acid12005470.070 Why?
Chromatin1201829340.070 Why?
I-kappa B Kinase120072520.070 Why?
Drug Therapy, Combination1201664890.070 Why?
Receptor Protein-Tyrosine Kinases2201516600.070 Why?
Histones1201625990.070 Why?
Precipitin Tests220048290.070 Why?
Skin Neoplasms2201656860.070 Why?
Neoplasm Invasiveness1201336160.070 Why?
Up-Regulation1201542170.070 Why?
Proteins2201861030.070 Why?
Sulfonamides2201219380.070 Why?
Epidermal Growth Factor120087080.060 Why?
Treatment Outcome42023631140.060 Why?
Prostate2202217740.060 Why?
Brain32021263850.060 Why?
Gene Deletion2201727510.060 Why?
Flow Cytometry1201559740.060 Why?
Nerve Tissue Proteins1201744620.060 Why?
Myocytes, Smooth Muscle220216870.060 Why?
Sepsis1201825930.060 Why?
Stress, Physiological1201114030.060 Why?
Genome-Wide Association Study22020122610.060 Why?
T-Lymphocytes, Regulatory1201729880.060 Why?
Agar12003560.060 Why?
Gene Expression Regulation, Developmental1201536170.060 Why?
Molecular Weight1200522550.060 Why?
Neovascularization, Pathologic2201526350.060 Why?
Anaphase120231200.060 Why?
Aspirin1201532820.060 Why?
Metformin120108350.050 Why?
Fertility220187810.050 Why?
Species Specificity1200724780.050 Why?
Mice, Inbred Strains2201718270.050 Why?
Down-Regulation1201030020.050 Why?
Nuclear Proteins1201758530.050 Why?
Acylation120221070.050 Why?
Amino Acid Substitution1200717910.050 Why?
Active Transport, Cell Nucleus120034430.050 Why?
Drug Synergism2201617920.050 Why?
Transfection2201658920.050 Why?
Prostatic Neoplasms32012111240.050 Why?
Aging1202186640.050 Why?
Open Reading Frames220188100.050 Why?
Neovascularization, Physiologic1200913510.050 Why?
Lipopolysaccharides2201922160.050 Why?
Dose-Response Relationship, Drug32016109430.050 Why?
Epithelial-Mesenchymal Transition220187130.050 Why?
DNA1201573010.050 Why?
MicroRNAs1201737520.050 Why?
Stem Cells1201435670.050 Why?
Proto-Oncogene Proteins B-raf1201020430.050 Why?
MAP Kinase Kinase Kinase 112020580.050 Why?
Genes, Tumor Suppressor1200510970.050 Why?
Genes, cdc120201160.050 Why?
Rats, Sprague-Dawley2202183010.050 Why?
Retroviridae120039140.050 Why?
Gene Expression Regulation12018120720.050 Why?
Epilepsy1201533100.040 Why?
Immunoblotting1200316820.040 Why?
Biomedical Research1201533090.040 Why?
Adipocytes1200611840.040 Why?
Receptor, Fibroblast Growth Factor, Type 2120201880.040 Why?
Receptors, Cytoplasmic and Nuclear120038710.040 Why?
Fatty Acids, Unsaturated120225460.040 Why?
Neoplasm Metastasis1200948510.040 Why?
Genetic Predisposition to Disease12020174460.040 Why?
Receptors, Androgen1200410580.040 Why?
Estrus12017810.040 Why?
Calcium Channels120216220.040 Why?
Decidua12018860.040 Why?
Eicosapentaenoic Acid120225820.040 Why?
Obesity32016127450.040 Why?
Transcription Factors32012122080.040 Why?
Androgens1200412810.040 Why?
Focal Adhesion Protein-Tyrosine Kinases120171820.040 Why?
Clinical Trials as Topic2201079130.040 Why?
Glycine120206710.040 Why?
Solubility1201810850.040 Why?
Binding Sites1200561140.040 Why?
Adjuvants, Immunologic1202210000.040 Why?
Fluphenazine12016360.040 Why?
Polyethylene Glycols1202211820.040 Why?
Retinoblastoma-Binding Protein 212016310.040 Why?
Regulatory Sequences, Nucleic Acid120207940.040 Why?
Serine120208260.040 Why?
RNA Interference3201128890.030 Why?
Chlorpromazine120161110.030 Why?
Gene Library2201010740.030 Why?
Radiation-Sensitizing Agents120183580.030 Why?
Embryo Implantation120182720.030 Why?
Sexual Maturation120172650.030 Why?
Imidazoles2201212060.030 Why?
Indans12016960.030 Why?
Growth120173760.030 Why?
Mice, Inbred BALB C2201863860.030 Why?
Cell Division1200345680.030 Why?
Docosahexaenoic Acids120228750.030 Why?
Subcellular Fractions120165470.030 Why?
Receptors, Dopamine120162950.030 Why?
Methylamines120161230.030 Why?
Cyclin-Dependent Kinase 312014110.030 Why?
Linkage Disequilibrium1202019970.030 Why?
Dopamine Antagonists120162960.030 Why?
HCT116 Cells120164080.030 Why?
Cyclooxygenase 1120151040.030 Why?
3' Untranslated Regions120175130.030 Why?
Cyclin-Dependent Kinase 812014520.030 Why?
Tumor Cells, Cultured2201863140.030 Why?
Neointima120151350.030 Why?
Puberty120174900.030 Why?
Poly(ADP-ribose) Polymerases120164400.030 Why?
Fluorouracil1201916190.030 Why?
DNA-Binding Proteins3201296480.030 Why?
Oligodendroglia120175170.030 Why?
Receptor, Insulin120178460.030 Why?
Mutant Proteins120155000.030 Why?
Benzimidazoles220128500.030 Why?
Amyloid Precursor Protein Secretases120175840.030 Why?
Genetic Vectors1200334200.030 Why?
Proteomics2202036380.030 Why?
Androgen Antagonists1202213770.030 Why?
Methylation1201611060.030 Why?
Ribosomal Protein S6 Kinases120132050.030 Why?
Receptors, Glucagon12013920.030 Why?
Cyclooxygenase Inhibitors120153710.030 Why?
Transcriptional Activation1201917830.030 Why?
Genes, BRCA2120166180.030 Why?
Castration120121590.030 Why?
Mass Spectrometry1202022030.030 Why?
Structure-Activity Relationship1201831290.030 Why?
Keratinocytes120167980.030 Why?
Genes, BRCA1120167810.030 Why?
Exons1201824370.030 Why?
Genetic Testing1200534440.030 Why?
Substrate Specificity1201618010.030 Why?
Cell Differentiation22006114830.030 Why?
Time Factors32019400750.030 Why?
Metabolomics1202014840.030 Why?
Phenols120154970.030 Why?
KATP Channels12011450.030 Why?
Chromones120111540.020 Why?
Phenylthiohydantoin120121930.020 Why?
Diabetes Mellitus1201057510.020 Why?
Genomics1200757200.020 Why?
TRPC Cation Channels120111210.020 Why?
Colorectal Neoplasms1201067730.020 Why?
Microtubule-Associated Proteins1201610860.020 Why?
Intracellular Membranes120113900.020 Why?
Cathepsins120112410.020 Why?
Green Fluorescent Proteins1201620880.020 Why?
Phagosomes120111930.020 Why?
Protein Transport1201619880.020 Why?
Chemotherapy, Adjuvant1201934790.020 Why?
Boron Compounds120111780.020 Why?
Models, Molecular2201554560.020 Why?
Proto-Oncogene Proteins c-raf120102030.020 Why?
Appetite Depressants120101100.020 Why?
Hyperplasia1201311850.020 Why?
Androstadienes120113460.020 Why?
Antineoplastic Agents, Hormonal1201815240.020 Why?
Allosteric Regulation120104080.020 Why?
Biphenyl Compounds120139130.020 Why?
Magnetic Resonance Imaging12016354210.020 Why?
Patch-Clamp Techniques120119640.020 Why?
Light1201513740.020 Why?
Disease Progression22019132840.020 Why?
p38 Mitogen-Activated Protein Kinases120126970.020 Why?
Cell Growth Processes120093990.020 Why?
Muscle, Smooth, Vascular1201515040.020 Why?
Membrane Potentials1201111370.020 Why?
Protein Subunits120119590.020 Why?
Mitogen-Activated Protein Kinase Kinases120106480.020 Why?
Quinolines120127320.020 Why?
Nitriles120129560.020 Why?
Genes, Reporter1201115470.020 Why?
Recombinant Fusion Proteins1201637720.020 Why?
Benzamides1201213790.020 Why?
Base Sequence12018127970.020 Why?
Simian virus 40120072950.020 Why?
Hydrogen-Ion Concentration1201125570.020 Why?
Models, Animal1201321710.020 Why?
Quinazolines1201313560.020 Why?
Lysosomes120118930.020 Why?
Cyclin-Dependent Kinase Inhibitor p21120073650.020 Why?
Neoplasm Proteins1201837030.020 Why?
Sex Characteristics1201625850.020 Why?
Nanoparticles1201719050.020 Why?
Adenosine Triphosphate1201220250.020 Why?
Pyrazoles1201519720.020 Why?
Genome, Human1201844200.020 Why?
Body Weight1201646690.020 Why?
Promoter Regions, Genetic1201658670.020 Why?
Extracellular Signal-Regulated MAP Kinases120076250.020 Why?
Kinetics1201264730.010 Why?
Aneuploidy120075300.010 Why?
Retinoblastoma Protein120077040.010 Why?
Calmodulin120032090.010 Why?
Phenotype12021163650.010 Why?
Skin1201643640.010 Why?
Karyopherins120031370.010 Why?
Feeding Behavior1201531880.010 Why?
Two-Hybrid System Techniques120044640.010 Why?
Cell Movement1201552170.010 Why?
Benzothiazoles120032480.010 Why?
Indoles1201018390.010 Why?
Dietary Fats1201020170.010 Why?
Testosterone1201224200.010 Why?
Phosphoric Monoester Hydrolases120034310.010 Why?
Pyridines1201328250.010 Why?
Multigene Family1200411020.010 Why?
Polymerase Chain Reaction1201061710.010 Why?
Adult320212140550.010 Why?
Reproducibility of Results12018199050.010 Why?
Cohort Studies12023405610.010 Why?
Gene Expression1201377990.010 Why?
Child22018777090.010 Why?
Telomerase120047300.010 Why?
Infant12021351360.010 Why?
Sequence Homology, Amino Acid1200428390.010 Why?
Genome1200718080.010 Why?
Prospective Studies12023532880.010 Why?
Transforming Growth Factor beta1200520070.010 Why?
Algorithms12017138810.010 Why?
Pregnancy12018291440.010 Why?
Cell Nucleus1200329690.010 Why?
Retrospective Studies12023774490.010 Why?
Aged, 80 and over12019577760.010 Why?
Middle Aged220192133830.010 Why?
Risk Assessment12015233380.010 Why?
Melanoma1201055100.010 Why?
Molecular Sequence Data12004181110.010 Why?
Aged120191632800.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.