Harvard Catalyst Profiles

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Alan N. Engelman, Ph.D.

Concepts (500)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Virus Integration94202430717.590 Why?
HIV Integrase66202412212.540 Why?
HIV-11472024694810.660 Why?
HIV Integrase Inhibitors2120231655.570 Why?
Integrases4320225205.450 Why?
DNA, Viral56202422005.420 Why?
Capsid2620244355.220 Why?
mRNA Cleavage and Polyadenylation Factors1720241024.280 Why?
Virus Replication53202224583.330 Why?
Intercellular Signaling Peptides and Proteins27202216563.250 Why?
Retroviridae1420248453.200 Why?
Capsid Proteins2020234672.490 Why?
Host-Pathogen Interactions19202214682.350 Why?
Active Transport, Cell Nucleus1720234311.960 Why?
Cell Nucleus15202428641.920 Why?
Nuclear Pore Complex Proteins1020231651.750 Why?
Spumavirus92020171.710 Why?
Adaptor Proteins, Signal Transducing16202128981.610 Why?
HIV Infections472024175351.580 Why?
Human Immunodeficiency Virus Proteins52021561.250 Why?
beta Karyopherins52019461.250 Why?
Virus Uncoating42022131.090 Why?
Protein Conformation18202139461.090 Why?
Cryoelectron Microscopy1120246451.090 Why?
Virus Latency720213591.030 Why?
Pyridones320218171.000 Why?
Protein Multimerization1220219590.960 Why?
HeLa Cells26202430730.960 Why?
Protein Binding32202493010.960 Why?
Cell Line462023155460.950 Why?
Lentivirus520225180.930 Why?
Transcription Factors182021121300.930 Why?
HEK293 Cells28202442630.920 Why?
Recombination, Genetic9201515250.860 Why?
gag Gene Products, Human Immunodeficiency Virus320192130.860 Why?
Chromatin9202229810.850 Why?
Models, Molecular26202453820.850 Why?
Virion1320224280.840 Why?
Catalytic Domain1320226980.810 Why?
Anti-HIV Agents12202245610.810 Why?
Moloney murine leukemia virus220141100.780 Why?
Viral Proteins10201718010.740 Why?
Polyadenylation220191140.730 Why?
DNA Nucleotidyltransferases1219961770.730 Why?
Nuclear Pore52023610.710 Why?
Proviruses1020233190.710 Why?
Heterocyclic Compounds, 3-Ring220202960.710 Why?
Nucleoproteins220131100.700 Why?
DNA, Complementary8200719840.690 Why?
Crystallography, X-Ray16202119470.660 Why?
Primates220205190.660 Why?
RNA-Binding Proteins4202218830.660 Why?
Cyclophilin A62021560.650 Why?
Gene Targeting420188400.640 Why?
Congresses as Topic120248110.630 Why?
Oxazines220203580.630 Why?
Drug Resistance, Viral820208680.620 Why?
Leukemia Virus, Murine102019950.600 Why?
Virus Assembly820211400.600 Why?
DNA18202371930.590 Why?
Simian immunodeficiency virus320208120.590 Why?
Nuclear Localization Signals42006780.580 Why?
Mammary Tumor Virus, Mouse22022410.580 Why?
HIV Seropositivity320239610.570 Why?
Allosteric Regulation1120234250.550 Why?
Nuclear Proteins10202257910.540 Why?
Binding Sites20202060010.530 Why?
Acquired Immunodeficiency Syndrome2202322050.520 Why?
Integrase Inhibitors32021120.510 Why?
RNA, Viral9202328680.490 Why?
Humans14920247661170.460 Why?
Jurkat Cells620217380.460 Why?
CD4-Positive T-Lymphocytes11202344080.450 Why?
HIV5201115870.450 Why?
Antiviral Agents5202330680.440 Why?
Structure-Activity Relationship11202130510.420 Why?
Molecular Sequence Data312013175970.410 Why?
Protein Structure, Tertiary13201737510.390 Why?
Polymerase Chain Reaction12201660590.380 Why?
Amino Acid Sequence232014134000.370 Why?
Genome, Viral520216740.370 Why?
DNA-Binding Proteins10201496010.370 Why?
Macromolecular Substances3201314300.360 Why?
Catalysis720157670.360 Why?
Piperazines2202025470.350 Why?
Reverse Transcription82020480.340 Why?
Karyopherins220091330.330 Why?
Mutation302021302090.330 Why?
Mutagenesis, Site-Directed9200716770.320 Why?
Animals5320221688000.320 Why?
Simian virus 40220072900.320 Why?
Gene Expression Regulation, Viral320214340.310 Why?
Mutation, Missense7201425900.300 Why?
Leukemia, Experimental220192240.300 Why?
HIV Antigens120093280.300 Why?
Retroviridae Infections220191480.290 Why?
Transcription, Genetic10201676000.290 Why?
HIV Reverse Transcriptase320212140.290 Why?
Chromosome Mapping1201646170.290 Why?
Synaptic Membranes12007880.280 Why?
Abelson murine leukemia virus41990410.270 Why?
Base Sequence182015124050.270 Why?
Adaptive Immunity320167330.270 Why?
Cytoplasm4202114980.260 Why?
Directed Molecular Evolution120071670.260 Why?
Nucleosomes320174920.260 Why?
Mucoproteins12005490.250 Why?
Genomics2202159260.250 Why?
Virus Internalization420215030.240 Why?
Recombinant Proteins10201964930.230 Why?
Nucleic Acid Conformation620219000.230 Why?
Gene Products, vpr42005330.220 Why?
High-Throughput Nucleotide Sequencing1201636650.220 Why?
Genome, Human2201644430.210 Why?
Growth Substances120057580.210 Why?
Multiprotein Complexes2202111070.200 Why?
vpr Gene Products, Human Immunodeficiency Virus42009360.200 Why?
Heart1201544190.200 Why?
Lens, Crystalline120043870.200 Why?
Amino Acid Substitution8202017420.200 Why?
Binding, Competitive2201911400.200 Why?
Acetates220143140.200 Why?
HIV Long Terminal Repeat32011860.190 Why?
Reverse Transcriptase Polymerase Chain Reaction1200945650.190 Why?
Rous sarcoma virus1202120.190 Why?
Microbial Sensitivity Tests2201219710.190 Why?
Mice222022818390.190 Why?
RNA, Messenger52019127750.180 Why?
Retroviridae Proteins21993930.180 Why?
Prions120221770.180 Why?
Protein-Tyrosine Kinases4201924250.180 Why?
Amides220204510.180 Why?
Interphase120212260.180 Why?
Pyrrolidinones220111160.170 Why?
HIV-2320091560.170 Why?
Nucleocapsid Proteins22021750.170 Why?
Gene Products, pol22017430.170 Why?
Conserved Sequence4200411590.170 Why?
Sequence Deletion7200914940.170 Why?
Gene Products, gag220173170.170 Why?
Horses120202940.170 Why?
DNA Footprinting42000970.170 Why?
Reverse Transcriptase Inhibitors220216180.170 Why?
Evolution, Molecular3202018890.170 Why?
Protein Interaction Domains and Motifs220204470.160 Why?
Viral Fusion Proteins120191000.160 Why?
Phenylalanine220223670.160 Why?
Cats120209720.160 Why?
Awards and Prizes120233650.160 Why?
Recombinant Fusion Proteins7201737330.160 Why?
Phosphorylation7202182920.160 Why?
Cattle3202038010.160 Why?
Magnesium320208150.160 Why?
Heart Defects, Congenital1201547120.150 Why?
Protein Structure, Quaternary320164230.150 Why?
Gene Silencing2202015040.150 Why?
Viral Matrix Proteins120191920.150 Why?
Fluoroimmunoassay12017300.150 Why?
Quinolines220147690.150 Why?
Attachment Sites, Microbiological11997260.150 Why?
Mutagenesis4200612270.150 Why?
Heterochromatin120202940.150 Why?
History, 21st Century1202415740.150 Why?
3' Untranslated Regions120205140.140 Why?
DNA Helicases120038520.140 Why?
Genetic Vectors2201934000.140 Why?
DNA Transposable Elements120017650.140 Why?
Cloning, Molecular6200541630.140 Why?
Alternative Splicing2201711030.140 Why?
Quinolones220113890.140 Why?
Solubility4201310770.140 Why?
Infectious Anemia Virus, Equine1199640.140 Why?
Tumor Virus Infections120194380.140 Why?
Repressor Proteins5202029740.140 Why?
Receptors, Virus120006510.140 Why?
Fluorescence120197510.130 Why?
Cytoskeletal Proteins2202113220.130 Why?
Pyridines2201928890.130 Why?
Birds220091650.130 Why?
Consensus Sequence220073630.130 Why?
Manganese219963950.130 Why?
Drug Evaluation, Preclinical2201913310.130 Why?
History, 20th Century1202427620.130 Why?
Chromatography, Gel520146310.130 Why?
Blotting, Western4201450200.120 Why?
Genetic Complementation Test320055560.120 Why?
RNA2202227160.120 Why?
Macrophages6202157760.120 Why?
Staining and Labeling2200910720.120 Why?
Sulfolobus solfataricus1201420.120 Why?
Mice, Knockout52017144560.120 Why?
Amino Acid Motifs220169240.120 Why?
Myeloid-Lymphoid Leukemia Protein120173090.120 Why?
Hematopoietic Stem Cells2201734050.120 Why?
Archaeal Proteins12014570.120 Why?
Virus Activation120163220.110 Why?
Mutant Proteins220144870.110 Why?
Models, Chemical120166070.110 Why?
Gene Deletion4200726670.110 Why?
Macaca mulatta1202023410.110 Why?
Fetal Death120154340.110 Why?
Escherichia coli6201542100.110 Why?
Immune Evasion120173760.110 Why?
Allosteric Site120131060.110 Why?
RNA Interference4201128280.110 Why?
High-Throughput Screening Assays120199380.110 Why?
Gene Knockdown Techniques2201616020.110 Why?
Promoter Regions, Genetic3201357840.110 Why?
Membrane Proteins2200678500.100 Why?
Oligodeoxyribonucleotides519997050.100 Why?
Protein Structure, Secondary3200512110.100 Why?
Sequence Homology, Amino Acid4200427430.100 Why?
Heart Septal Defects, Ventricular120154770.100 Why?
DNA Primers4201128240.100 Why?
Transfection4200457390.100 Why?
Histidine320203010.100 Why?
Homeodomain Proteins3201724300.100 Why?
Glutathione Transferase220045630.100 Why?
Hydrophobic and Hydrophilic Interactions120133900.100 Why?
Cells, Cultured82021189670.100 Why?
Thiophenes120165700.100 Why?
Virus Release12012350.100 Why?
Benzimidazoles120178620.100 Why?
Substrate Specificity6201517510.090 Why?
Hematopoiesis2201720600.090 Why?
Cell Transformation, Neoplastic3199028380.090 Why?
Cell Lineage2201725730.090 Why?
HMGA1a Protein22003630.090 Why?
Dimerization120128810.090 Why?
Cyclosporine220117770.090 Why?
Oncogene Protein pp60(v-src)11990760.090 Why?
Models, Biological3202194450.090 Why?
Protein Engineering120145500.090 Why?
Kinetics5200262730.090 Why?
Guanosine Triphosphate220173140.090 Why?
Sumoylation12011830.090 Why?
Cleavage And Polyadenylation Specificity Factor12010160.090 Why?
Pluripotent Stem Cells120178080.090 Why?
Temperature5200422270.090 Why?
Metals120147090.090 Why?
Peptide Fragments3202051260.090 Why?
Sequence Alignment3201421740.090 Why?
HIV Core Protein p24120102450.080 Why?
Visna-maedi virus1200960.080 Why?
Drosophila Proteins1201917040.080 Why?
Genome2201517530.080 Why?
Uracil120112100.080 Why?
Retroelements120111630.080 Why?
Proto-Oncogenes119903200.080 Why?
Transposases320151060.080 Why?
Histones2201725910.080 Why?
NM23 Nucleoside Diphosphate Kinases12009210.080 Why?
Carbon-Nitrogen Ligases12009270.080 Why?
Immunity, Innate2202130790.080 Why?
DNA-(Apurinic or Apyrimidinic Site) Lyase12009710.080 Why?
Biotinylation120091840.080 Why?
Zidovudine120106260.080 Why?
Carrier State120125290.080 Why?
Viral Envelope Proteins120126390.080 Why?
T-Lymphocyte Subsets1201618140.080 Why?
Indoles1201618330.070 Why?
DNA Shuffling1200750.070 Why?
Luciferases120097120.070 Why?
Glycine220226710.070 Why?
Immunoprecipitation220148740.070 Why?
Exodeoxyribonucleases120091910.070 Why?
Genes, ras119906560.070 Why?
Transforming Growth Factor beta1201519960.070 Why?
Fibroblasts3201241620.070 Why?
Nucleoside Deaminases12007580.070 Why?
Histone Deacetylase Inhibitors120127780.070 Why?
Models, Genetic3200534480.070 Why?
Gene Expression Regulation42021119060.070 Why?
Coenzymes120071010.070 Why?
Crows1200650.070 Why?
Antigens, Polyomavirus Transforming220042550.070 Why?
AT-Hook Motifs1200620.070 Why?
T-Lymphocytes52019102600.070 Why?
Crystallization220055180.070 Why?
Restriction Mapping220058480.060 Why?
Plasmids3201122670.060 Why?
Gene Expression3201375820.060 Why?
Models, Animal1201221200.060 Why?
Carrier Proteins3201249100.060 Why?
Genes, Reporter1200915240.060 Why?
Lamin Type A120061860.060 Why?
Cell Cycle1201329200.060 Why?
Protein Biosynthesis1201220910.060 Why?
Repetitive Sequences, Nucleic Acid120077800.060 Why?
Nucleotides220204530.060 Why?
Defective Viruses21995890.060 Why?
Trans-Activators2201728490.060 Why?
Sequence Homology, Nucleic Acid2200110560.060 Why?
Stereoisomerism220196120.060 Why?
Coculture Techniques1200913360.060 Why?
Induced Pluripotent Stem Cells1201618840.060 Why?
HIV Protease12005990.060 Why?
Adenine120109940.060 Why?
Mice, Inbred NOD2202118370.060 Why?
RNA, Small Interfering2201134240.060 Why?
Oncogenes1199012320.060 Why?
alpha Karyopherins12004420.060 Why?
ran GTP-Binding Protein12004530.060 Why?
Gene Expression Regulation, Developmental1201536060.060 Why?
Biological Transport, Active120043230.060 Why?
MicroRNAs1202037870.060 Why?
Antiretroviral Therapy, Highly Active1201218990.060 Why?
DNA Mutational Analysis3200541120.050 Why?
Polysaccharide-Lyases12003480.050 Why?
beta-Galactosidase120045730.050 Why?
RNA-Directed DNA Polymerase220122220.050 Why?
Proto-Oncogene Proteins2201745210.050 Why?
Circular Dichroism220003330.050 Why?
Cell Differentiation22017116420.050 Why?
CpG Islands1200712070.050 Why?
Electrophoresis, Polyacrylamide Gel3200017240.050 Why?
Antigens, Nuclear120031820.050 Why?
Myocardium1201547660.050 Why?
Precipitin Tests120038120.050 Why?
Escherichia coli Proteins1200910560.050 Why?
Glutathione120045890.050 Why?
Open Reading Frames120058200.050 Why?
Serine220208280.050 Why?
Cell Line, Tumor42017170710.050 Why?
Cricetinae2202024130.050 Why?
DNA Repair2201620480.050 Why?
Luminescent Proteins120048390.050 Why?
Drug Design2201710400.050 Why?
Molecular Conformation120225390.050 Why?
Phytic Acid12020220.050 Why?
rev Gene Products, Human Immunodeficiency Virus12000260.050 Why?
Disease Reservoirs120211230.050 Why?
Deuterium Exchange Measurement12020310.050 Why?
Gene Products, rev12000290.050 Why?
Signal Transduction12004236050.050 Why?
DNA, Satellite12020670.040 Why?
Mice, Inbred C57BL22017223410.040 Why?
Viral Core Proteins120201580.040 Why?
Drugs, Investigational120222110.040 Why?
Viremia120237270.040 Why?
Histone Acetyltransferases120223320.040 Why?
5' Untranslated Regions120212550.040 Why?
Peptide Mapping220072590.040 Why?
Virology12020760.040 Why?
Cell Extracts120001340.040 Why?
Proteasome Endopeptidase Complex1200613180.040 Why?
Transcription Initiation Site120201890.040 Why?
Phosphoproteins1200924450.040 Why?
Computational Biology3201035650.040 Why?
Transduction, Genetic120028980.040 Why?
Nucleocapsid12019610.040 Why?
Centromere120202140.040 Why?
Mammals1200511260.040 Why?
Aotidae22012570.040 Why?
Enzyme Inhibitors2200737220.040 Why?
Safety1200411570.040 Why?
Sheep1202214450.040 Why?
DNA Replication2202014280.040 Why?
Chromosomes, Human, Pair 19120203500.040 Why?
Rats32021237170.040 Why?
Down-Regulation1200629270.040 Why?
Core Binding Factor Alpha 1 Subunit120191550.040 Why?
Fibroblast Growth Factors120058710.040 Why?
Protein Folding220008680.040 Why?
Genes, pol21995530.040 Why?
Green Fluorescent Proteins1200420620.040 Why?
Permeability120207260.040 Why?
Genes, myc120193910.040 Why?
Models, Theoretical1201035610.040 Why?
Chromatography, Affinity219965210.040 Why?
High Mobility Group Proteins119981790.040 Why?
Ribonuclease, Pancreatic119981120.040 Why?
Cell Cycle Proteins1200934360.040 Why?
K562 Cells120196440.040 Why?
Ribonucleoproteins120203590.040 Why?
Spodoptera120171400.040 Why?
Molecular Dynamics Simulation120204220.040 Why?
Poly A120171800.040 Why?
Monocytes3202125910.030 Why?
Mass Spectrometry1200421950.030 Why?
Microscopy, Fluorescence2202026270.030 Why?
Magnetic Resonance Spectroscopy2200536780.030 Why?
RNA Polymerase II120215490.030 Why?
Glutamine120205750.030 Why?
Rabbits1200347300.030 Why?
Surface Plasmon Resonance120172680.030 Why?
Suppression, Genetic119961900.030 Why?
Dogs1202138240.030 Why?
Lymphocyte Activation1200755030.030 Why?
Carboxylic Acids12016910.030 Why?
Static Electricity120172580.030 Why?
Mice, SCID1202126260.030 Why?
Transcriptional Activation1202217430.030 Why?
Fluorescent Dyes1200419280.030 Why?
Educational Status1202325100.030 Why?
Bacteriophage M1312015390.030 Why?
AT Rich Sequence12015100.030 Why?
Leukocytes, Mononuclear1202218520.030 Why?
Turkeys11994440.030 Why?
RNA Precursors120161960.030 Why?
Morphogenesis119997430.030 Why?
DNA, Superhelical12015520.030 Why?
Core Binding Factor Alpha 2 Subunit120173520.030 Why?
COS Cells1199611350.030 Why?
Gene Knockout Techniques120178000.030 Why?
Schools1202314950.030 Why?
Endothelium120177680.030 Why?
Proteins2200859950.030 Why?
Viral Load1202333860.030 Why?
Photochemistry119942380.030 Why?
Chromatography, Ion Exchange120142890.030 Why?
Microscopy, Electron, Transmission120156830.030 Why?
Point Mutation2199615910.030 Why?
X-Ray Diffraction120144130.030 Why?
RNA Splicing120179020.030 Why?
Flow Cytometry2201658810.030 Why?
DNA, Single-Stranded119943510.030 Why?
Cell Division2201244660.030 Why?
Molecular Structure1199618810.020 Why?
Polynucleotide 5'-Hydroxyl-Kinase1199160.020 Why?
Indoleacetic Acids12012440.020 Why?
Receptors, Notch120167510.020 Why?
Microscopy, Electron1199525430.020 Why?
Uracil-DNA Glycosidase12011350.020 Why?
Disease Models, Animal22021183210.020 Why?
Protein Transport2200919390.020 Why?
Enhancer Elements, Genetic1201713630.020 Why?
Genetic Predisposition to Disease12013180760.020 Why?
Nucleotidyltransferases119932430.020 Why?
Sequence Analysis, DNA2201447800.020 Why?
Oligonucleotides120145610.020 Why?
Proto-Oncogene Proteins c-bcr11990210.020 Why?
Water1199614160.020 Why?
Rats, Sprague-Dawley1202181130.020 Why?
Ubiquitin-Protein Ligases2201218970.020 Why?
Proto-Oncogene Proteins c-abl119901450.020 Why?
Phosphotyrosine119904590.020 Why?
Avian Sarcoma Viruses12009770.020 Why?
Female520233962330.020 Why?
Ultraviolet Rays1199410990.020 Why?
Endopeptidases119927600.020 Why?
Zinc119936750.020 Why?
Intracellular Space120091980.020 Why?
Alkaline Phosphatase119918550.020 Why?
Drug Discovery1201610650.020 Why?
Microscopy, Confocal1201419670.020 Why?
Phosphates119917630.020 Why?
Gene Regulatory Networks1201617500.020 Why?
Templates, Genetic120081880.020 Why?
Mediator Complex120081060.020 Why?
Gene Products, vif12007310.020 Why?
vif Gene Products, Human Immunodeficiency Virus12007510.020 Why?
Mice, Transgenic1201995400.020 Why?
Leupeptins120061120.020 Why?
Surface Properties1200911520.020 Why?
Lymphocytes2199426020.020 Why?
Cell Transformation, Viral119875270.020 Why?
rab GTP-Binding Proteins120082470.020 Why?
Tyrosine1199014270.020 Why?
Immune System120117990.020 Why?
Treatment Outcome12012652190.020 Why?
Protein Processing, Post-Translational1199319620.020 Why?
Single-Cell Analysis1201625360.020 Why?
Cytidine Deaminase120072490.020 Why?
Vesicular Transport Proteins120083760.010 Why?
RNA, Transfer120072840.010 Why?
Proto-Oncogene Proteins c-myc119909980.010 Why?
RNA Processing, Post-Transcriptional120073920.010 Why?
Amino Acids1199017100.010 Why?
Replication Origin12004770.010 Why?
Enzyme Activation1200935840.010 Why?
Phenotype12020167160.010 Why?
Proto-Oncogene Proteins p21(ras)1199017650.010 Why?
Species Specificity2199724060.010 Why?
Cell Proliferation12017104330.010 Why?
Chromosomes120035790.010 Why?
Tumor Suppressor Proteins1201027950.010 Why?
Specimen Handling120047040.010 Why?
Hematopoietic Stem Cell Transplantation1201757520.010 Why?
Lymphoma1198818960.010 Why?
Phylogeny1200628380.010 Why?
Intracellular Signaling Peptides and Proteins1200828790.010 Why?
Guidelines as Topic1200413940.010 Why?
Ultracentrifugation119961550.010 Why?
GRB2 Adaptor Protein119951010.010 Why?
Sequence Homology119951970.010 Why?
Spectrin119951740.010 Why?
Ribonuclease H11994520.010 Why?
Solutions119954050.010 Why?
Hydrogen Bonding119942900.010 Why?
B-Lymphocytes1198847820.010 Why?
Male220233639350.010 Why?
Gene Expression Profiling1201095270.010 Why?
Lysine119979940.010 Why?
Molecular Weight1199421610.010 Why?
Genetic Variation1200666120.010 Why?
Time Factors12011401080.010 Why?
Aged120201712190.000 Why?
Middle Aged120202230830.000 Why?
Adult120202231390.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.