Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Alan N. Engelman, Ph.D.

Concepts (497)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Virus Integration91202229916.950 Why?
HIV Integrase65202212013.080 Why?
HIV-11442023693910.680 Why?
HIV Integrase Inhibitors2120231425.990 Why?
Integrases4320225335.750 Why?
DNA, Viral54202222255.160 Why?
Capsid2520234364.730 Why?
mRNA Cleavage and Polyadenylation Factors162022983.640 Why?
Virus Replication53202225343.480 Why?
Intercellular Signaling Peptides and Proteins27202216763.400 Why?
Capsid Proteins2020234792.620 Why?
Retroviridae1320229142.550 Why?
Host-Pathogen Interactions19202214772.440 Why?
Active Transport, Cell Nucleus1720234432.060 Why?
Nuclear Pore Complex Proteins1020231651.870 Why?
Spumavirus92020161.820 Why?
Adaptor Proteins, Signal Transducing16202129161.690 Why?
HIV Infections452023167181.620 Why?
Cell Nucleus14202329691.470 Why?
beta Karyopherins52019471.320 Why?
Human Immunodeficiency Virus Proteins52021651.310 Why?
Virus Uncoating42022131.160 Why?
Protein Conformation18202140111.130 Why?
Pyridones320217121.120 Why?
Virus Latency720213581.110 Why?
Cryoelectron Microscopy1020215711.040 Why?
Protein Multimerization1220219701.010 Why?
Lentivirus520225011.000 Why?
Cell Line462023159970.980 Why?
Transcription Factors182021122080.970 Why?
Chromatin9202229340.910 Why?
gag Gene Products, Human Immunodeficiency Virus320192220.910 Why?
Protein Binding31202193860.900 Why?
Recombination, Genetic9201515860.890 Why?
Virion1320224330.890 Why?
Anti-HIV Agents12202242560.870 Why?
Catalytic Domain1320226980.860 Why?
Models, Molecular25202254560.860 Why?
HeLa Cells25202131280.840 Why?
HEK293 Cells27202142040.840 Why?
Moloney murine leukemia virus220141390.830 Why?
Heterocyclic Compounds, 3-Ring220202150.800 Why?
Polyadenylation220191170.790 Why?
DNA Nucleotidyltransferases1219961930.780 Why?
Viral Proteins10201719000.770 Why?
Proviruses1020233180.760 Why?
Nuclear Pore52023700.750 Why?
Nucleoproteins220131150.740 Why?
DNA, Complementary8200720500.720 Why?
Primates220205450.700 Why?
Crystallography, X-Ray16202120110.700 Why?
Cyclophilin A62021570.690 Why?
Oxazines220202980.690 Why?
RNA-Binding Proteins4202219030.680 Why?
Gene Targeting420188800.670 Why?
Drug Resistance, Viral820208200.660 Why?
Leukemia Virus, Murine1020191170.640 Why?
Virus Assembly820211440.630 Why?
Simian immunodeficiency virus320208460.620 Why?
Nuclear Localization Signals42006800.620 Why?
Mammary Tumor Virus, Mouse22022610.610 Why?
DNA18202373010.610 Why?
HIV Seropositivity320239710.600 Why?
Allosteric Regulation1120234080.580 Why?
Nuclear Proteins10202258530.560 Why?
Binding Sites20202061140.550 Why?
Integrase Inhibitors32021120.550 Why?
Acquired Immunodeficiency Syndrome2202322320.540 Why?
RNA, Viral9202329020.510 Why?
Jurkat Cells620217430.490 Why?
CD4-Positive T-Lymphocytes11202343860.470 Why?
Antiviral Agents5202329870.470 Why?
HIV5201116040.470 Why?
Humans14620237443430.470 Why?
Structure-Activity Relationship11202131290.430 Why?
Molecular Sequence Data312013181110.420 Why?
Protein Structure, Tertiary13201738460.410 Why?
Polymerase Chain Reaction12201661710.400 Why?
Genome, Viral520216670.400 Why?
DNA-Binding Proteins10201496480.390 Why?
Amino Acid Sequence232014138150.380 Why?
Catalysis720157610.380 Why?
Macromolecular Substances3201314540.380 Why?
Piperazines2202024880.370 Why?
Reverse Transcription82020470.360 Why?
Karyopherins220091370.350 Why?
Mutation302021297860.350 Why?
Animals5320221687570.340 Why?
Mutagenesis, Site-Directed9200717230.340 Why?
Simian virus 40220072950.340 Why?
Gene Expression Regulation, Viral320214420.330 Why?
Leukemia, Experimental220192460.320 Why?
Mutation, Missense7201425640.320 Why?
HIV Antigens120093470.320 Why?
Retroviridae Infections220191510.310 Why?
HIV Reverse Transcriptase320212130.310 Why?
Transcription, Genetic10201677220.300 Why?
Chromosome Mapping1201647400.300 Why?
Synaptic Membranes12007910.290 Why?
Abelson murine leukemia virus41990430.290 Why?
Adaptive Immunity320167130.280 Why?
Base Sequence182015127970.280 Why?
Directed Molecular Evolution120071600.280 Why?
Cytoplasm4202115390.280 Why?
Nucleosomes320174940.270 Why?
Mucoproteins12005500.270 Why?
Genomics2202157200.270 Why?
Virus Internalization420215010.250 Why?
Nucleic Acid Conformation620219130.240 Why?
Recombinant Proteins10201966220.240 Why?
Gene Products, vpr42005360.230 Why?
High-Throughput Nucleotide Sequencing1201635970.230 Why?
Genome, Human2201644200.220 Why?
Growth Substances120057840.220 Why?
Multiprotein Complexes2202111190.220 Why?
Lens, Crystalline120043880.210 Why?
vpr Gene Products, Human Immunodeficiency Virus42009390.210 Why?
Acetates220143110.210 Why?
Binding, Competitive2201911570.210 Why?
Microbial Sensitivity Tests2201218770.210 Why?
HIV Long Terminal Repeat32011880.210 Why?
Heart1201544670.210 Why?
Amino Acid Substitution8202017910.200 Why?
Rous sarcoma virus1202140.200 Why?
Mice222022811830.200 Why?
Reverse Transcriptase Polymerase Chain Reaction1200947510.200 Why?
Retroviridae Proteins21993980.190 Why?
RNA, Messenger52019130330.190 Why?
Prions120221800.190 Why?
Protein-Tyrosine Kinases4201924550.190 Why?
Interphase120212260.190 Why?
Amides220204590.190 Why?
Pyrrolidinones220111170.180 Why?
HIV-2320091670.180 Why?
Gene Products, pol22017470.180 Why?
Nucleocapsid Proteins22021770.180 Why?
Gene Products, gag220173370.180 Why?
DNA Footprinting42000980.180 Why?
Conserved Sequence4200412020.180 Why?
Horses120203040.180 Why?
Sequence Deletion7200915260.180 Why?
Reverse Transcriptase Inhibitors220216150.170 Why?
Viral Fusion Proteins12019950.170 Why?
Protein Interaction Domains and Motifs220204740.170 Why?
Phenylalanine220223650.170 Why?
Evolution, Molecular3202019400.170 Why?
Cats120209980.170 Why?
Magnesium320208130.170 Why?
Recombinant Fusion Proteins7201737720.170 Why?
Awards and Prizes120233750.170 Why?
Heart Defects, Congenital1201545840.160 Why?
Viral Matrix Proteins120191860.160 Why?
Quinolines220147320.160 Why?
Phosphorylation7202184360.160 Why?
Cattle3202039220.160 Why?
Protein Structure, Quaternary320164360.160 Why?
Fluoroimmunoassay12017330.160 Why?
Gene Silencing2202015380.160 Why?
Attachment Sites, Microbiological11997260.160 Why?
Heterochromatin120202960.160 Why?
3' Untranslated Regions120205130.160 Why?
Mutagenesis4200612660.150 Why?
DNA Transposable Elements120017480.150 Why?
Genetic Vectors2201934200.150 Why?
DNA Helicases120038590.150 Why?
Quinolones220113670.150 Why?
Solubility4201310850.150 Why?
Infectious Anemia Virus, Equine1199640.150 Why?
Cloning, Molecular6200543200.150 Why?
Alternative Splicing2201711170.150 Why?
Receptors, Virus120006480.140 Why?
Tumor Virus Infections120194520.140 Why?
Fluorescence120197510.140 Why?
Repressor Proteins5202030230.140 Why?
Pyridines2201928250.140 Why?
Birds220091630.140 Why?
Cytoskeletal Proteins2202113640.140 Why?
Consensus Sequence220073770.140 Why?
Manganese219964080.140 Why?
Chromatography, Gel520146680.130 Why?
Drug Evaluation, Preclinical2201913750.130 Why?
Genetic Complementation Test320055620.130 Why?
Macrophages6202156550.130 Why?
Blotting, Western4201451790.130 Why?
Mice, Knockout52017145570.130 Why?
RNA2202227490.130 Why?
Sulfolobus solfataricus1201420.130 Why?
Myeloid-Lymphoid Leukemia Protein120172940.130 Why?
Staining and Labeling2200911000.130 Why?
Amino Acid Motifs220169360.130 Why?
Archaeal Proteins12014560.120 Why?
Virus Activation120163190.120 Why?
Hematopoietic Stem Cells2201733860.120 Why?
Mutant Proteins220145000.120 Why?
Models, Chemical120166260.120 Why?
Macaca mulatta1202023750.120 Why?
Gene Deletion4200727510.120 Why?
Immune Evasion120173600.120 Why?
Allosteric Site120131030.120 Why?
Escherichia coli6201542170.110 Why?
Fetal Death120154480.110 Why?
High-Throughput Screening Assays120199440.110 Why?
RNA Interference4201128890.110 Why?
Gene Knockdown Techniques2201616550.110 Why?
Promoter Regions, Genetic3201358670.110 Why?
Heart Septal Defects, Ventricular120154880.110 Why?
Oligodeoxyribonucleotides519997080.110 Why?
Membrane Proteins2200678800.110 Why?
Protein Structure, Secondary3200512460.110 Why?
Sequence Homology, Amino Acid4200428390.110 Why?
DNA Primers4201128920.110 Why?
Hydrophobic and Hydrophilic Interactions120134070.110 Why?
Histidine320203130.100 Why?
Glutathione Transferase220045950.100 Why?
Homeodomain Proteins3201724210.100 Why?
Virus Release12012390.100 Why?
Transfection4200458920.100 Why?
Cells, Cultured82021192290.100 Why?
Thiophenes120165880.100 Why?
Benzimidazoles120178500.100 Why?
Substrate Specificity6201518010.100 Why?
Cell Lineage2201725040.100 Why?
Hematopoiesis2201720720.100 Why?
HMGA1a Protein22003640.100 Why?
Dimerization120128930.100 Why?
Cell Transformation, Neoplastic3199029420.090 Why?
Oncogene Protein pp60(v-src)11990770.090 Why?
Cyclosporine220117860.090 Why?
Protein Engineering120145400.090 Why?
Sumoylation12011830.090 Why?
Guanosine Triphosphate220173210.090 Why?
Temperature5200422060.090 Why?
Cleavage And Polyadenylation Specificity Factor12010170.090 Why?
Kinetics5200264730.090 Why?
Models, Biological3202195830.090 Why?
Metals120147190.090 Why?
Peptide Fragments3202050970.090 Why?
Uracil120111650.090 Why?
Pluripotent Stem Cells120177950.090 Why?
Visna-maedi virus1200970.090 Why?
HIV Core Protein p24120102560.090 Why?
Sequence Alignment3201422560.090 Why?
Drosophila Proteins1201917030.090 Why?
Retroelements120111640.090 Why?
Transposases320151070.090 Why?
Proto-Oncogenes119903210.090 Why?
Histones2201725990.090 Why?
NM23 Nucleoside Diphosphate Kinases12009190.090 Why?
Carbon-Nitrogen Ligases12009280.090 Why?
Genome2201518080.090 Why?
Immunity, Innate2202129580.080 Why?
Biotinylation120091790.080 Why?
DNA-(Apurinic or Apyrimidinic Site) Lyase12009710.080 Why?
Carrier State120125180.080 Why?
Zidovudine120106200.080 Why?
Viral Envelope Proteins120126350.080 Why?
T-Lymphocyte Subsets1201618380.080 Why?
DNA Shuffling1200750.080 Why?
Glycine220226710.080 Why?
Exodeoxyribonucleases120091800.080 Why?
Indoles1201618390.080 Why?
Immunoprecipitation220149050.080 Why?
Luciferases120097330.080 Why?
Nucleoside Deaminases12007580.080 Why?
Transforming Growth Factor beta1201520070.080 Why?
Genes, ras119906900.080 Why?
Fibroblasts3201241610.070 Why?
Histone Deacetylase Inhibitors120127890.070 Why?
Crows1200650.070 Why?
Coenzymes12007910.070 Why?
AT-Hook Motifs1200620.070 Why?
Antigens, Polyomavirus Transforming220042580.070 Why?
Models, Genetic3200534940.070 Why?
Gene Expression Regulation42021120720.070 Why?
Crystallization220055240.070 Why?
T-Lymphocytes52019101800.070 Why?
Restriction Mapping220058780.070 Why?
Plasmids3201123070.070 Why?
Models, Animal1201221710.070 Why?
Lamin Type A120061900.070 Why?
Gene Expression3201377990.070 Why?
Genes, Reporter1200915470.070 Why?
Induced Pluripotent Stem Cells1201617360.060 Why?
Adenine120109360.060 Why?
Carrier Proteins3201250210.060 Why?
Repetitive Sequences, Nucleic Acid120077980.060 Why?
Defective Viruses219951120.060 Why?
Cell Cycle1201329670.060 Why?
Stereoisomerism220196240.060 Why?
Coculture Techniques1200913410.060 Why?
Protein Biosynthesis1201221260.060 Why?
Sequence Homology, Nucleic Acid2200110850.060 Why?
Nucleotides220204640.060 Why?
HIV Protease12005960.060 Why?
Trans-Activators2201729240.060 Why?
alpha Karyopherins12004410.060 Why?
ran GTP-Binding Protein12004540.060 Why?
Mice, Inbred NOD2202118780.060 Why?
RNA, Small Interfering2201135050.060 Why?
Oncogenes1199012650.060 Why?
Gene Expression Regulation, Developmental1201536170.060 Why?
Biological Transport, Active120043490.060 Why?
MicroRNAs1202037520.060 Why?
Antiretroviral Therapy, Highly Active1201218730.060 Why?
Polysaccharide-Lyases12003480.060 Why?
DNA Mutational Analysis3200541860.060 Why?
beta-Galactosidase120045730.060 Why?
RNA-Directed DNA Polymerase220122480.060 Why?
CpG Islands1200711720.060 Why?
Cell Differentiation22017114830.050 Why?
Circular Dichroism220003540.050 Why?
Proto-Oncogene Proteins2201745540.050 Why?
Antigens, Nuclear120031920.050 Why?
Electrophoresis, Polyacrylamide Gel3200018010.050 Why?
Myocardium1201547760.050 Why?
Precipitin Tests120038290.050 Why?
Escherichia coli Proteins1200910500.050 Why?
Glutathione120045890.050 Why?
Cell Line, Tumor42017166890.050 Why?
Serine220208260.050 Why?
Open Reading Frames120058100.050 Why?
Cricetinae2202024720.050 Why?
DNA Repair2201620460.050 Why?
Luminescent Proteins120048530.050 Why?
Phytic Acid12020230.050 Why?
Molecular Conformation120225630.050 Why?
rev Gene Products, Human Immunodeficiency Virus12000280.050 Why?
Mice, Inbred C57BL22017218270.050 Why?
Deuterium Exchange Measurement12020300.050 Why?
Gene Products, rev12000310.050 Why?
Disease Reservoirs120211310.050 Why?
Drug Design2201710760.050 Why?
Signal Transduction12004234030.050 Why?
DNA, Satellite12020690.050 Why?
5' Untranslated Regions120212490.050 Why?
Viral Core Proteins120201620.050 Why?
Drugs, Investigational120222140.050 Why?
Viremia120237360.050 Why?
Histone Acetyltransferases120223360.050 Why?
Peptide Mapping220072630.050 Why?
Cell Extracts120001380.050 Why?
Virology12020770.050 Why?
Proteasome Endopeptidase Complex1200613380.050 Why?
Transcription Initiation Site120201960.040 Why?
Phosphoproteins1200924400.040 Why?
Nucleocapsid12019590.040 Why?
Computational Biology3201035210.040 Why?
Aotidae22012590.040 Why?
DNA Replication2202013990.040 Why?
Transduction, Genetic120029130.040 Why?
Centromere120202200.040 Why?
Mammals1200511430.040 Why?
Sheep1202214370.040 Why?
Protein Folding220008430.040 Why?
Chromosomes, Human, Pair 19120203670.040 Why?
Safety1200411860.040 Why?
Core Binding Factor Alpha 1 Subunit120191640.040 Why?
Fibroblast Growth Factors120058790.040 Why?
Enzyme Inhibitors2200737980.040 Why?
Down-Regulation1200630020.040 Why?
Rats32021242600.040 Why?
Genes, pol21995510.040 Why?
Permeability120207380.040 Why?
Green Fluorescent Proteins1200420880.040 Why?
Genes, myc120193990.040 Why?
Chromatography, Affinity219965490.040 Why?
Models, Theoretical1201035890.040 Why?
High Mobility Group Proteins119981870.040 Why?
Ribonuclease, Pancreatic119981540.040 Why?
K562 Cells120196340.040 Why?
Cell Cycle Proteins1200934620.040 Why?
Molecular Dynamics Simulation120204130.040 Why?
Spodoptera120171530.040 Why?
Poly A120171850.040 Why?
Ribonucleoproteins120203810.040 Why?
Monocytes3202125960.040 Why?
Mass Spectrometry1200422030.040 Why?
RNA Polymerase II120215510.040 Why?
Microscopy, Fluorescence2202026990.040 Why?
Glutamine120205780.040 Why?
Surface Plasmon Resonance120172740.040 Why?
Rabbits1200348940.040 Why?
Magnetic Resonance Spectroscopy2200537600.040 Why?
Suppression, Genetic119961960.040 Why?
Dogs1202139120.030 Why?
Carboxylic Acids12016970.030 Why?
Static Electricity120172670.030 Why?
Lymphocyte Activation1200755240.030 Why?
Fluorescent Dyes1200419170.030 Why?
Mice, SCID1202127160.030 Why?
Bacteriophage M1312015390.030 Why?
Transcriptional Activation1202217830.030 Why?
AT Rich Sequence12015110.030 Why?
Educational Status1202325400.030 Why?
Leukocytes, Mononuclear1202218360.030 Why?
Turkeys11994480.030 Why?
DNA, Superhelical12015500.030 Why?
Core Binding Factor Alpha 2 Subunit120173450.030 Why?
Morphogenesis119997520.030 Why?
Schools1202314330.030 Why?
RNA Precursors120162080.030 Why?
Gene Knockout Techniques120178090.030 Why?
Viral Load1202332990.030 Why?
COS Cells1199611610.030 Why?
Endothelium120177780.030 Why?
Photochemistry119942380.030 Why?
Proteins2200861030.030 Why?
Chromatography, Ion Exchange120143050.030 Why?
Microscopy, Electron, Transmission120157120.030 Why?
X-Ray Diffraction120144200.030 Why?
Point Mutation2199616230.030 Why?
RNA Splicing120179070.030 Why?
Flow Cytometry2201659740.030 Why?
DNA, Single-Stranded119943540.030 Why?
Polynucleotide 5'-Hydroxyl-Kinase1199180.030 Why?
Indoleacetic Acids12012440.030 Why?
Cell Division2201245680.030 Why?
Molecular Structure1199618990.030 Why?
Receptors, Notch120167390.030 Why?
Disease Models, Animal22021180290.030 Why?
Microscopy, Electron1199526450.020 Why?
Uracil-DNA Glycosidase12011310.020 Why?
Nucleotidyltransferases119932200.020 Why?
Genetic Predisposition to Disease12013174460.020 Why?
Enhancer Elements, Genetic1201713410.020 Why?
Protein Transport2200919880.020 Why?
Proto-Oncogene Proteins c-bcr11990200.020 Why?
Oligonucleotides120145720.020 Why?
Sequence Analysis, DNA2201448030.020 Why?
Water1199613950.020 Why?
Rats, Sprague-Dawley1202183010.020 Why?
Ubiquitin-Protein Ligases2201218610.020 Why?
Proto-Oncogene Proteins c-abl119901460.020 Why?
Phosphotyrosine119904570.020 Why?
Female520233801940.020 Why?
Ultraviolet Rays1199410600.020 Why?
Avian Sarcoma Viruses12009840.020 Why?
Endopeptidases119927720.020 Why?
Zinc119936840.020 Why?
Intracellular Space120092120.020 Why?
Microscopy, Confocal1201419700.020 Why?
Alkaline Phosphatase119918650.020 Why?
Drug Discovery1201610580.020 Why?
Phosphates119917860.020 Why?
Gene Regulatory Networks1201617080.020 Why?
Templates, Genetic120082110.020 Why?
Gene Products, vif12007330.020 Why?
Mediator Complex120081090.020 Why?
vif Gene Products, Human Immunodeficiency Virus12007530.020 Why?
Mice, Transgenic1201997340.020 Why?
Leupeptins120061220.020 Why?
Surface Properties1200911840.020 Why?
Lymphocytes2199426170.020 Why?
Single-Cell Analysis1201621830.020 Why?
Cell Transformation, Viral119875650.020 Why?
rab GTP-Binding Proteins120082460.020 Why?
Tyrosine1199014610.020 Why?
Treatment Outcome12012631140.020 Why?
Immune System120118050.020 Why?
Protein Processing, Post-Translational1199319900.020 Why?
Cytidine Deaminase120072520.020 Why?
Vesicular Transport Proteins120083770.020 Why?
Proto-Oncogene Proteins c-myc119909870.020 Why?
RNA, Transfer120073160.020 Why?
Amino Acids1199017360.020 Why?
Replication Origin12004770.010 Why?
RNA Processing, Post-Transcriptional120074360.010 Why?
Enzyme Activation1200937010.010 Why?
Proto-Oncogene Proteins p21(ras)1199016920.010 Why?
Phenotype12020163650.010 Why?
Species Specificity2199724780.010 Why?
Cell Proliferation12017104810.010 Why?
Chromosomes120035960.010 Why?
Tumor Suppressor Proteins1201028490.010 Why?
Specimen Handling120046940.010 Why?
Hematopoietic Stem Cell Transplantation1201754420.010 Why?
Phylogeny1200628030.010 Why?
Lymphoma1198818770.010 Why?
Guidelines as Topic1200414050.010 Why?
Intracellular Signaling Peptides and Proteins1200829150.010 Why?
Ultracentrifugation119961820.010 Why?
GRB2 Adaptor Protein119951030.010 Why?
Sequence Homology119952030.010 Why?
Ribonuclease H11994450.010 Why?
Spectrin119951770.010 Why?
Solutions119954260.010 Why?
Hydrogen Bonding119942930.010 Why?
B-Lymphocytes1198846650.010 Why?
Male220233501180.010 Why?
Gene Expression Profiling1201094380.010 Why?
Lysine1199710070.010 Why?
Molecular Weight1199422550.010 Why?
Genetic Variation1200665440.010 Why?
Time Factors12011400750.010 Why?
Aged120201632800.000 Why?
Middle Aged120202133830.000 Why?
Adult120202140550.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.