Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Brendan D. Manning, Ph.D.

Concepts (429)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
TOR Serine-Threonine Kinases52201820585.960 Why?
Multiprotein Complexes33201711205.030 Why?
Proto-Oncogene Proteins c-akt22202124482.890 Why?
Tumor Suppressor Proteins31202228022.690 Why?
Signal Transduction512024233762.250 Why?
Tuberous Sclerosis15202210302.110 Why?
Activating Transcription Factor 442021821.750 Why?
Lysosomes520229201.390 Why?
Phosphatidylinositol 3-Kinases13201928641.370 Why?
Protein Kinases14200916121.310 Why?
Metabolic Networks and Pathways520247891.220 Why?
Sterol Regulatory Element Binding Proteins32017251.190 Why?
Proteins17201660291.070 Why?
Protein Biosynthesis7201721051.060 Why?
Sterol Regulatory Element Binding Protein 1420151351.060 Why?
Metabolism220191930.920 Why?
Ribosomal Protein S6 Kinases720132030.850 Why?
Purine Nucleotides22022270.810 Why?
Neoplasms182024220720.750 Why?
IMP Dehydrogenase12020330.710 Why?
Ribonucleosides12020790.690 Why?
Transcription Factors152014121030.690 Why?
Sirolimus10201715470.670 Why?
Serine220228300.640 Why?
Glutathione220215820.640 Why?
Nuclear Respiratory Factor 122015210.630 Why?
Energy Metabolism5201928690.630 Why?
AMP-Activated Protein Kinases620176000.620 Why?
Animals6920241679630.620 Why?
NADP120192230.610 Why?
Amino Acids6202217140.600 Why?
Intracellular Signaling Peptides and Proteins3202228730.600 Why?
Mycophenolic Acid120203430.600 Why?
Proto-Oncogene Proteins6201744900.590 Why?
Sterol Regulatory Element Binding Protein 222015560.590 Why?
Nucleotides220174500.580 Why?
Insulin10202165970.580 Why?
Drug Resistance, Fungal12017730.580 Why?
Liver6202175090.550 Why?
Phosphotransferases (Alcohol Group Acceptor)120194360.550 Why?
Phosphorylation17201983130.540 Why?
Fatty Acids2202218040.530 Why?
Mice452022812080.530 Why?
Lipogenesis220152100.530 Why?
Genes, Tumor Suppressor7201710550.520 Why?
Glycolysis420218280.520 Why?
Tetrahydrofolates12016580.520 Why?
Oncogene Proteins120197190.510 Why?
GTPase-Activating Proteins520224750.510 Why?
Glucose6202143510.490 Why?
Lipid Metabolism3201519020.470 Why?
HeLa Cells7201731050.470 Why?
Lipids3201633360.460 Why?
Giant Cells120141850.460 Why?
Purines220226050.450 Why?
Elongation Factor 2 Kinase12013100.450 Why?
Mice, Knockout152022143720.450 Why?
Cell Division5200944630.450 Why?
Repressor Proteins8200529810.440 Why?
Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)1201380.440 Why?
Dihydroorotase1201380.440 Why?
Peptide Chain Elongation, Translational12013310.440 Why?
Aspartate Carbamoyltransferase12013190.440 Why?
Monomeric GTP-Binding Proteins520122000.430 Why?
Ribosomal Protein S6 Kinases, 90-kDa22010550.420 Why?
Ribosomal Protein S6 Kinases, 70-kDa320171010.420 Why?
Models, Biological10201294670.410 Why?
Carrier Proteins6201249380.410 Why?
Enzyme Inhibitors2202037260.400 Why?
Proteasome Endopeptidase Complex2201513130.390 Why?
Microtubule Proteins32000620.390 Why?
Saccharomyces cerevisiae5201726980.380 Why?
Metformin220179120.380 Why?
Hepatocytes3201712290.380 Why?
Cell Line, Tumor142021169390.360 Why?
Isocitrate Dehydrogenase120169290.350 Why?
Immunoblotting5201716490.350 Why?
Pentose Phosphate Pathway120101260.350 Why?
Feedback, Physiological320114760.350 Why?
Monoacylglycerol Lipases12010360.340 Why?
Cell Proliferation122021104460.330 Why?
RNA Interference7201828460.330 Why?
Nutritional Physiological Phenomena120113630.320 Why?
Neuropeptides520129430.320 Why?
Cell Line112021156200.320 Why?
Proto-Oncogene Proteins p21(ras)3201517280.320 Why?
Adipocytes3201211790.310 Why?
Tacrolimus Binding Proteins120091930.310 Why?
Caenorhabditis elegans2201614440.300 Why?
Glioblastoma2202134840.300 Why?
Neoplasm Proteins1202036100.300 Why?
Cell Growth Processes120083840.290 Why?
Humans7320247606210.280 Why?
Fibroblasts7202140900.270 Why?
Analgesics1201310650.270 Why?
Transcription, Genetic4201675930.260 Why?
Mitochondria3201636000.260 Why?
Myocardium1201947000.260 Why?
Mice, Inbred C57BL122021220230.260 Why?
Heart1201943930.260 Why?
Homeostasis4201633060.250 Why?
Glycogen Synthase Kinase 3120064100.240 Why?
Chromatography, Liquid320199870.230 Why?
HEK293 Cells4201942640.220 Why?
Saccharomyces cerevisiae Proteins4200018540.220 Why?
Drug Delivery Systems2201722210.220 Why?
Neurons2202294260.210 Why?
Gene Expression Regulation42019119030.210 Why?
3T3-L1 Cells320132090.200 Why?
Gene Expression Regulation, Enzymologic1200611730.200 Why?
Phosphotransferases120023030.200 Why?
Feedback120057910.190 Why?
Animal Feed120211120.190 Why?
Fungal Proteins320009110.190 Why?
Hypoxia-Inducible Factor 1, alpha Subunit320186210.180 Why?
Pyrimidines1201330160.180 Why?
Microtubule-Associated Proteins3200010770.180 Why?
Gene Expression Regulation, Neoplastic4201985150.180 Why?
Citric Acid Cycle120212300.180 Why?
Antibiotics, Antineoplastic420156750.180 Why?
Molecular Motor Proteins120001050.170 Why?
Genetic Techniques120024280.170 Why?
Gene Knockdown Techniques3201516170.170 Why?
Carcinoma, Hepatocellular1201222990.170 Why?
Mice, Transgenic5202195300.160 Why?
HCT116 Cells220174020.160 Why?
Drug Resistance, Neoplasm2201352530.160 Why?
Nitrogen Isotopes12019850.160 Why?
Amino Acid Sequence62012134510.160 Why?
Phospholipids120227890.160 Why?
Adaptor Proteins, Signal Transducing5201328950.160 Why?
Amino Acids, Sulfur12018160.160 Why?
Food220137710.150 Why?
Phosphoribosylglycinamide Formyltransferase1201730.150 Why?
Carbon Isotopes120194590.150 Why?
Adenosylmethionine Decarboxylase12017110.150 Why?
Thymidylate Synthase12017740.150 Why?
Isotope Labeling120193920.140 Why?
Genes, Lethal120172250.140 Why?
Cells, Cultured92019189570.140 Why?
Cell Cycle4201729340.140 Why?
Hydrogen Sulfide120181410.140 Why?
Polyamines120171330.140 Why?
Insulin-Like Growth Factor I2201919280.140 Why?
RNA, Ribosomal120172260.140 Why?
Tumor Cells, Cultured5201761310.140 Why?
Methenyltetrahydrofolate Cyclohydrolase12016100.130 Why?
Methylenetetrahydrofolate Dehydrogenase (NADP)12016170.130 Why?
Oxidoreductases Acting on CH-CH Group Donors120171740.130 Why?
ATP Citrate (pro-S)-Lyase12016220.130 Why?
Liver Neoplasms1201243190.130 Why?
Molecular Sequence Data62012176240.130 Why?
Fasting1202216030.130 Why?
rho GTP-Binding Proteins119972770.130 Why?
Substrate Specificity3200717920.130 Why?
Glutamine120195760.130 Why?
Tandem Mass Spectrometry2201911890.130 Why?
Cytosol120198870.130 Why?
Pressure1201911560.130 Why?
Epistasis, Genetic120173500.130 Why?
Lysophosphatidylcholines12015770.130 Why?
Autophagy2201413370.120 Why?
Brain12022269510.120 Why?
Drug Screening Assays, Antitumor120177170.120 Why?
Embryo, Mammalian1202116740.120 Why?
Class III Phosphatidylinositol 3-Kinases12014170.120 Why?
Eukaryotic Initiation Factor-2120161800.120 Why?
Triglycerides1202224760.120 Why?
Glutarates120162440.120 Why?
Nuclear Proteins1200957910.120 Why?
Cytoskeletal Proteins1200013430.120 Why?
RNA, Small Interfering5201834420.120 Why?
Nuclear Receptor Coactivators12014610.120 Why?
Caloric Restriction120162960.120 Why?
PTEN Phosphohydrolase4201711150.110 Why?
Drug Therapy120175040.110 Why?
Cell Polarity220136380.110 Why?
Nucleoside-Phosphate Kinase12013250.110 Why?
Oxidation-Reduction1201922220.110 Why?
Lymphangioleiomyomatosis120152030.110 Why?
Mice, Inbred NOD1201718370.110 Why?
GTP-Binding Proteins119979510.110 Why?
Macrophage Activation120165540.110 Why?
Thiolester Hydrolases12013850.110 Why?
Hamartoma220052350.100 Why?
Phospholipid Transfer Proteins12013880.100 Why?
Disease Susceptibility1201917910.100 Why?
Fluorouracil1201716310.100 Why?
Cytoskeleton1199711670.100 Why?
Biosynthetic Pathways120131350.100 Why?
Isoenzymes1201716900.100 Why?
Mice, SCID1201726270.100 Why?
Organ Specificity1201719550.100 Why?
Phosphoric Monoester Hydrolases220054120.100 Why?
RNA Splicing120169150.100 Why?
Ferritins120145970.100 Why?
Intercellular Signaling Peptides and Proteins2200916520.100 Why?
Proliferating Cell Nuclear Antigen120122830.090 Why?
Benzoquinones120111980.090 Why?
Binding Sites3200960480.090 Why?
Methotrexate1201717190.090 Why?
GTP Phosphohydrolases120145180.090 Why?
PPAR gamma220134840.090 Why?
Drosophila1201714920.090 Why?
Nerve Sheath Neoplasms120111670.090 Why?
Molecular Targeted Therapy3201728030.090 Why?
Caenorhabditis elegans Proteins120168660.090 Why?
Light1201613440.090 Why?
Lactams, Macrocyclic120113150.090 Why?
Drosophila Proteins2201716990.080 Why?
Phosphothreonine12009620.080 Why?
Seizures1202229170.080 Why?
Macrophages2201657450.080 Why?
Phosphoserine120092030.080 Why?
Adipogenesis120123580.080 Why?
Protein Kinase C-alpha120091130.080 Why?
Longevity1201610500.080 Why?
Feeding Behavior1202131850.080 Why?
Cell Line, Transformed120108690.080 Why?
Immunohistochemistry32012110710.080 Why?
Metabolomics3201716280.080 Why?
14-3-3 Proteins120092210.080 Why?
Vertebrates120092280.080 Why?
Insulin Resistance4201439590.080 Why?
Neurofibromin 2120092700.080 Why?
Cell Survival4201957970.080 Why?
Lymph Nodes1201934860.080 Why?
Angiomyolipoma120091840.070 Why?
Boronic Acids120129140.070 Why?
Phosphoprotein Phosphatases120093300.070 Why?
Reperfusion Injury1201410230.070 Why?
Cell Enlargement12007600.070 Why?
Mutation52017299320.070 Why?
5' Untranslated Regions120082560.070 Why?
Vascular Endothelial Growth Factor A1201834840.070 Why?
Mass Spectrometry2201521920.070 Why?
Cell Cycle Proteins3201534460.070 Why?
Protein Binding3201493350.070 Why?
Immediate-Early Proteins120094490.070 Why?
Models, Animal2201121170.070 Why?
Neovascularization, Physiologic2201813360.070 Why?
ras Proteins1201110520.070 Why?
Conserved Sequence1200911670.070 Why?
Iron1201417860.070 Why?
Pyrazines1201211990.070 Why?
Muscles1201115810.070 Why?
CD8-Positive T-Lymphocytes1201945500.060 Why?
Esophageal Diseases120061680.060 Why?
Cell Membrane1201536820.060 Why?
Hypothalamus120119980.060 Why?
Multienzyme Complexes220086660.060 Why?
Amino Acid Substitution1200917370.060 Why?
Dose-Response Relationship, Drug12017108270.060 Why?
Herpesvirus 8, Human120062550.060 Why?
3T3 Cells2200410850.060 Why?
Enzyme Activation2201736020.060 Why?
Pancreas1201116770.060 Why?
Blotting, Western2200950390.060 Why?
Sequence Alignment1200821760.060 Why?
Carcinoma, Non-Small-Cell Lung2201352510.060 Why?
RNA, Messenger22009127660.060 Why?
Cell Size120056240.060 Why?
Protein Footprinting12002100.050 Why?
Receptors, Chemokine120066550.050 Why?
Energy Intake1201121290.050 Why?
DNA Footprinting12002970.050 Why?
NF-kappa B1201124880.050 Why?
Cell Movement2202252060.050 Why?
Molecular Weight2200221860.050 Why?
Male920183597440.050 Why?
Two-Hybrid System Techniques120024580.050 Why?
MicroRNAs1201737900.050 Why?
Pheromones22000930.050 Why?
Multiple Myeloma1201951300.050 Why?
Interleukin-42201611300.050 Why?
Polymerase Chain Reaction2201160680.040 Why?
Biomedical Research1201634260.040 Why?
Leptin1200815910.040 Why?
T-Lymphocytes12017101810.040 Why?
Carbon Cycle12019150.040 Why?
eIF-2 Kinase220111440.040 Why?
Viral Proteins1200618020.040 Why?
Adipose Tissue1201133010.040 Why?
DNA-Binding Proteins2201495850.040 Why?
Carbon120226690.040 Why?
Cystathionine gamma-Lyase12018360.040 Why?
Genomics2201357940.040 Why?
Gastrointestinal Tract120048300.040 Why?
Metabolic Diseases120046860.040 Why?
Genes, Fungal119994390.040 Why?
Ischemia2201818930.040 Why?
K562 Cells120196400.040 Why?
Burkholderia cepacia11996220.040 Why?
Cell Transformation, Neoplastic1200628280.030 Why?
Genes, Essential120171840.030 Why?
Kidney Neoplasms2201243120.030 Why?
S-Adenosylmethionine120172130.030 Why?
Cytotoxicity, Immunologic1201913510.030 Why?
RNA Precursors120162120.030 Why?
Protein Stability120175660.030 Why?
Phospholipases A2120151970.030 Why?
Chromatography, High Pressure Liquid1201915440.030 Why?
Chromatin Assembly and Disassembly120196330.030 Why?
Disease Progression12012135020.030 Why?
Amino Acids, Essential12014260.030 Why?
Sequence Homology, Amino Acid1199927530.030 Why?
DNA Primers1199928190.030 Why?
Gene Deletion1200226680.030 Why?
Naphthyridines120151410.030 Why?
Physical Conditioning, Animal120183660.030 Why?
Membrane Proteins1201178500.030 Why?
Prostatic Neoplasms12017113450.030 Why?
Diet, Protein-Restricted12014730.030 Why?
Sensitivity and Specificity12009146600.030 Why?
Protein-Tyrosine Kinases1200324180.030 Why?
Endoplasmic Reticulum2201111320.030 Why?
Mice, 129 Strain120143720.030 Why?
Thymine Nucleotides12013590.030 Why?
Endothelial Cells1200635390.030 Why?
Phagosomes120141990.030 Why?
Chitin12013330.030 Why?
Acetylation1201610620.030 Why?
Immunologic Memory1201913540.030 Why?
STAT6 Transcription Factor120131930.030 Why?
Inhibitory Concentration 50120134650.030 Why?
Dose-Response Relationship, Radiation120148810.020 Why?
Disease Models, Animal32018181370.020 Why?
Apoptosis1200895010.020 Why?
Oxidative Phosphorylation120144950.020 Why?
Microtubules1199710720.020 Why?
Chemokines120169620.020 Why?
Genome, Bacterial119967700.020 Why?
Gene Knockout Techniques120148020.020 Why?
Antineoplastic Agents22011136300.020 Why?
Goals120167080.020 Why?
Nitric Oxide1201921410.020 Why?
Antineoplastic Combined Chemotherapy Protocols12011117120.020 Why?
Kidney Diseases, Cystic120121830.020 Why?
In Situ Nick-End Labeling120116130.020 Why?
Brain Neoplasms1201189860.020 Why?
Arachnoid12009500.020 Why?
Interleukin-61201932150.020 Why?
Gene Regulatory Networks1201717410.020 Why?
Oxidative Stress2201131060.020 Why?
Lung Neoplasms12013132620.020 Why?
HSP90 Heat-Shock Proteins120114230.020 Why?
Lymphocyte Activation1201954960.020 Why?
Transfection2200957810.020 Why?
Genome1201617390.020 Why?
Obesity12010129220.020 Why?
Protein Processing, Post-Translational1201619740.020 Why?
Base Sequence11999124460.020 Why?
Phenylbutyrates12008720.020 Why?
Tumor Suppressor Protein p532201129190.020 Why?
Cell Death1201316720.020 Why?
High-Throughput Screening Assays120139440.020 Why?
Adaptation, Physiological1201412960.020 Why?
Fluorescent Antibody Technique1201124710.020 Why?
Peptides1199943540.020 Why?
Stress, Physiological1201413980.020 Why?
Oncogene Protein v-akt120061290.020 Why?
Drosophila melanogaster1201517100.020 Why?
Epigenesis, Genetic1201937580.020 Why?
DNA Replication1201314120.020 Why?
Insulin Receptor Substrate Proteins120085570.020 Why?
Rupture, Spontaneous120063560.020 Why?
Histones1201625830.020 Why?
Cisplatin1201116440.020 Why?
Lipopolysaccharides1201322090.020 Why?
Mice, Inbred BALB C1201462160.020 Why?
Paracrine Communication120062770.020 Why?
Peutz-Jeghers Syndrome12004590.010 Why?
Female520183912700.010 Why?
Phosphoproteins2200324400.010 Why?
Inflammation Mediators1201318810.010 Why?
Neurilemmoma120095230.010 Why?
Reactive Oxygen Species1201121380.010 Why?
DNA Damage1201324420.010 Why?
Sarcoma, Kaposi120063760.010 Why?
Promoter Regions, Genetic1201457850.010 Why?
Models, Genetic1201334420.010 Why?
Precipitin Tests120038140.010 Why?
Cell Differentiation12019114810.010 Why?
Body Weight1201246110.010 Why?
Phenotype11999165460.010 Why?
Electrophoresis, Polyacrylamide Gel1200317440.010 Why?
Chemical Fractionation12000620.010 Why?
B-Lymphocytes1201447420.010 Why?
Centrifugation, Density Gradient120002990.010 Why?
Biological Assay120036300.010 Why?
Meningioma1200912210.010 Why?
Syndrome1200632800.010 Why?
Mutagenesis, Site-Directed1200316930.010 Why?
Mice, Nude1200636070.010 Why?
Protein Interaction Mapping120036170.010 Why?
Sucrose120001560.010 Why?
Sequence Analysis120002400.010 Why?
Colonic Polyps120045510.010 Why?
Rats12015237110.010 Why?
Dimerization120008910.010 Why?
Flow Cytometry1200958700.010 Why?
Neoplasms, Experimental1200312290.010 Why?
Plasmids1200322750.010 Why?
Magnetic Resonance Imaging12005362900.010 Why?
Adenosine Triphosphate1200419930.010 Why?
Aging1201686510.010 Why?
Down-Regulation1200429130.010 Why?
Point Mutation1200215940.010 Why?
Replicon11996340.010 Why?
Pseudomonas119961230.010 Why?
Biodegradation, Environmental119962180.010 Why?
DNA, Ribosomal119962850.010 Why?
Chromosomes, Bacterial119962800.010 Why?
RNA, Bacterial119963850.010 Why?
Protein Structure, Tertiary1200038000.010 Why?
Genes, Bacterial1199610710.010 Why?
DNA Transposable Elements119967560.010 Why?
RNA, Ribosomal, 16S1199610060.010 Why?
DNA, Bacterial1199614560.010 Why?
Phylogeny1199627750.010 Why?
Chromosome Mapping1199646250.000 Why?
United States12016724610.000 Why?
Child, Preschool12008420630.000 Why?
Treatment Outcome12012650170.000 Why?
Aged, 80 and over12006589950.000 Why?
Retrospective Studies12006803720.000 Why?
Aged120061691520.000 Why?
Middle Aged120062203520.000 Why?
Adult120062199940.000 Why?
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Concepts (429)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.