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Bruce Yankner, M.D.,Ph.D.

Concepts (407)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Amyloid beta-Peptides36202335871.640 Why?
Alzheimer Disease31202380371.440 Why?
Aging20202386641.250 Why?
Repressor Proteins6202130231.180 Why?
Amyloid beta-Protein Precursor13201611211.110 Why?
Neurons31202293381.100 Why?
Hypothalamus2201710630.710 Why?
Caenorhabditis elegans Proteins320228520.640 Why?
Longevity3202210700.590 Why?
Amyloid820067950.560 Why?
Presenilins12016540.550 Why?
Brain222021263850.520 Why?
Neural Stem Cells220198510.470 Why?
I-kappa B Kinase220182520.450 Why?
Amnesia120152480.440 Why?
Membrane Proteins14200678800.430 Why?
Stress, Physiological3202114030.420 Why?
Oxidative Stress8201430860.420 Why?
Apoptosis11202197270.420 Why?
Hippocampus10201536750.410 Why?
Neurotoxins320022370.400 Why?
Nervous System320025540.390 Why?
Neurodegenerative Diseases3201610610.380 Why?
Presenilin-11220086350.370 Why?
Nerve Degeneration820027480.370 Why?
Induced Pluripotent Stem Cells2201917360.370 Why?
Gene Regulatory Networks1201917080.360 Why?
tau Proteins5202318680.350 Why?
Endopeptidases220057720.340 Why?
NF-kappa B3201724990.340 Why?
Transcription Factors42019122080.290 Why?
Peptide Fragments11201850970.290 Why?
Animals5720231687570.290 Why?
Cells, Cultured242018192290.290 Why?
Nerve Tissue Proteins6201344620.290 Why?
Gonadotropin-Releasing Hormone1201312050.290 Why?
Nerve Growth Factors720005740.290 Why?
Presenilin-2620081060.280 Why?
Astrocytes4201812700.280 Why?
DNA-Binding Proteins3201996480.260 Why?
Cerebral Cortex12200857080.260 Why?
Autophagy4201513000.250 Why?
Neuroprotective Agents320149410.240 Why?
Signal Transduction92017234030.240 Why?
Mice, Transgenic5202397340.230 Why?
Trans-Activators3200529240.230 Why?
Histone Acetyltransferases120053360.230 Why?
Neurofibrillary Tangles420004390.220 Why?
Gene Expression Regulation112021120720.210 Why?
Synapses4200817280.210 Why?
Transfection9200558920.210 Why?
MicroRNAs2201737520.210 Why?
Receptors, Cell Surface5200028660.210 Why?
Mice252023811830.200 Why?
Amyloid Precursor Protein Secretases420165840.200 Why?
DNA Damage3201524320.200 Why?
Nuclear Proteins4200858530.200 Why?
Down Syndrome320028800.190 Why?
Protein Processing, Post-Translational4200019900.190 Why?
Oncogene Proteins120057490.190 Why?
Active Transport, Cell Nucleus120024430.190 Why?
Plaque, Amyloid320007290.180 Why?
Parkinson Disease2200527750.180 Why?
Evolution, Molecular1200819400.170 Why?
Caspases220009280.170 Why?
Rats172008242600.170 Why?
Nuclear Lamina12019460.170 Why?
Peptide Hydrolases120026340.170 Why?
Disease Progression22015132840.170 Why?
Mice, 129 Strain120193860.160 Why?
Oligonucleotides220215720.160 Why?
Congo Red21996460.160 Why?
Cell Membrane3200537480.160 Why?
Humans6220237443430.160 Why?
Gene Expression Profiling3202194380.150 Why?
Protein Precursors3199111540.150 Why?
Receptor-Interacting Protein Serine-Threonine Kinases120181430.150 Why?
Cognition Disorders2201040430.150 Why?
Podocytes120213960.150 Why?
Mice, Knockout72019145570.140 Why?
Cell Line132021159970.140 Why?
Cytoskeletal Proteins2199913640.140 Why?
Mutation82008297860.140 Why?
Forkhead Transcription Factors2202216130.130 Why?
Calcium2200657560.130 Why?
Axons3201816840.130 Why?
Apolipoproteins E2201914380.130 Why?
Spastic Paraplegia, Hereditary119981570.130 Why?
Neurofibrils11995760.130 Why?
Pheochromocytoma619913370.130 Why?
Tumor Cells, Cultured6200263140.130 Why?
In Situ Hybridization, Fluorescence1202126490.130 Why?
Dopamine1200215910.130 Why?
RNA-Binding Proteins2201919030.130 Why?
GATA4 Transcription Factor120151310.120 Why?
Cyclin-Dependent Kinases220106710.120 Why?
Adaptation, Physiological1202113120.120 Why?
Caenorhabditis elegans2202214190.120 Why?
Single-Cell Analysis2202221830.120 Why?
Apolipoprotein E4120186680.120 Why?
Synucleins220051100.120 Why?
Mitochondria2201035200.120 Why?
Cell Differentiation82019114830.120 Why?
Qc-SNARE Proteins12013210.110 Why?
RNA, Messenger22008130330.110 Why?
Langerhans Cells119941730.110 Why?
Species Specificity3200824780.110 Why?
CA3 Region, Hippocampal12013560.110 Why?
Exosomes120174170.110 Why?
RNA Interference2201928890.110 Why?
Phagosomes120141930.110 Why?
Ubiquitin-Activating Enzymes12013830.110 Why?
Cell Death2201417060.110 Why?
Transcription, Genetic3200877220.110 Why?
Autistic Disorder1202211850.110 Why?
Neuroglia120189270.110 Why?
RNA2202127490.110 Why?
Cell Nucleus4201429690.110 Why?
Fibroblasts3201941610.110 Why?
Neurogenesis120198380.100 Why?
DNA Repair3201320460.100 Why?
Phosphorylation7201884360.100 Why?
Lewy Body Disease120142290.100 Why?
Ubiquitination2201310120.100 Why?
Aspartic Acid Endopeptidases220053110.100 Why?
Antioxidants3200816630.100 Why?
Islet Amyloid Polypeptide31996410.100 Why?
Chromatin Immunoprecipitation120148930.100 Why?
Histone Demethylases120133210.100 Why?
Frontotemporal Dementia120142480.100 Why?
Suppressor of Cytokine Signaling Proteins120111750.100 Why?
Solubility3200010850.090 Why?
Tachykinins11990780.090 Why?
Protein Transport1201619880.090 Why?
Reactive Oxygen Species2201020770.090 Why?
Substance P119913350.090 Why?
Mice, Inbred C57BL62019218270.090 Why?
Cell Survival4202158820.090 Why?
Synaptic Transmission3201811780.090 Why?
Aged, 80 and over72021577760.090 Why?
Protein Structure, Tertiary3201338460.080 Why?
Phosphoproteins3201824400.080 Why?
Protein Kinase C1199312270.080 Why?
Inflammation22015106380.080 Why?
HeLa Cells4201331280.080 Why?
Peroxiredoxins12008510.080 Why?
PC12 Cells320003300.080 Why?
Cell Adhesion2199231440.080 Why?
alpha-Synuclein220057230.080 Why?
Amino Acids1199317360.070 Why?
Ubiquitin-Protein Ligases2201318610.070 Why?
Dendrites119904850.070 Why?
Receptor, Notch1220005020.070 Why?
Disease Models, Animal22023180290.070 Why?
Thioredoxins120082130.070 Why?
Down-Regulation1201430020.070 Why?
Subcellular Fractions220055470.070 Why?
Proteins4200861030.070 Why?
Transcriptional Activation2200517830.070 Why?
Cerebral Arterial Diseases11986820.070 Why?
Fetus3200218800.070 Why?
Nerve Regeneration120117880.070 Why?
Sirtuins120083230.070 Why?
Gene Expression Regulation, Developmental1199736170.070 Why?
PTEN Phosphohydrolase1201111420.070 Why?
Epitopes2199725710.070 Why?
Octamer Transcription Factors12005230.070 Why?
Amygdala1201313150.060 Why?
Aged820211632800.060 Why?
Nuclear Matrix-Associated Proteins12005450.060 Why?
Heparin1199216370.060 Why?
Up-Regulation1201442170.060 Why?
Golgi Apparatus219984100.060 Why?
Genomic Instability120086950.060 Why?
Granuloma119863190.060 Why?
Copper120063660.060 Why?
Cats219969980.060 Why?
Phosphatidylinositol 3-Kinases2201029380.060 Why?
Histones1201325990.060 Why?
Endoplasmic Reticulum2200011440.060 Why?
Neurites219973880.050 Why?
Biological Transport3199921180.050 Why?
Antibodies1199124600.050 Why?
Receptors, N-Methyl-D-Aspartate120088950.050 Why?
Carbonyl Cyanide m-Chlorophenyl Hydrazone12002240.050 Why?
Uncoupling Agents12002450.050 Why?
Vasculitis119865190.050 Why?
Genes, Recessive120056410.050 Why?
Blotting, Western2200851790.050 Why?
Gene Deletion2200027510.050 Why?
Zinc120066840.050 Why?
Purines120055940.050 Why?
Insulin-Like Growth Factor I1201020150.050 Why?
Nervous System Diseases1199216220.050 Why?
Carbocyanines120021740.050 Why?
Homeostasis2202133400.050 Why?
14-3-3 Proteins120022140.050 Why?
Tyrosine 3-Monooxygenase120023750.050 Why?
Phylogeny1200828030.050 Why?
RNA, Small Interfering2201335050.050 Why?
Fluorescent Antibody Technique1200525050.050 Why?
Genes, Reporter1200515470.050 Why?
Sclerosis120212130.050 Why?
In Situ Nick-End Labeling120026430.050 Why?
Recombinant Proteins4200266220.050 Why?
Chromosomes, Human, Pair 16120223540.050 Why?
Receptors, Notch120057390.050 Why?
Calcium-Calmodulin-Dependent Protein Kinases219994940.050 Why?
Apoptosis Regulatory Proteins1200611570.050 Why?
Substantia Nigra120023530.050 Why?
Microglia2201812660.040 Why?
Intracellular Signaling Peptides and Proteins2201329150.040 Why?
Glycogen Synthase Kinase 3219994300.040 Why?
Biopolymers120001890.040 Why?
Microscopy, Confocal1200519700.040 Why?
Chromosome Disorders120225140.040 Why?
Microscopy, Fluorescence2199826990.040 Why?
Receptors, Drug119791600.040 Why?
HIV1198616040.040 Why?
Promoter Regions, Genetic2201558670.040 Why?
Molecular Sequence Data52008181110.040 Why?
Islets of Langerhans2199613520.040 Why?
Protease Inhibitors219937910.040 Why?
Callithrix11998930.040 Why?
Apolipoprotein E312018970.040 Why?
Cytoskeleton2202111850.040 Why?
Superoxide Dismutase120005970.040 Why?
Nuclear Envelope119791720.040 Why?
Adenomatous Polyposis Coli Protein119981880.040 Why?
Staurosporine120182510.040 Why?
Chromosome Deletion1202214010.040 Why?
Diabetes Mellitus1199657510.040 Why?
Albuminuria120216820.040 Why?
Receptors, Nerve Growth Factor319902000.040 Why?
Chromatin1200829340.040 Why?
DNA Breaks, Double-Stranded220135940.040 Why?
Epigenesis, Genetic1201036470.040 Why?
Benzimidazoles120028500.040 Why?
Amino Acid Sequence41993138150.040 Why?
beta Catenin2199910590.040 Why?
Lysosomes220108930.040 Why?
Tissue Distribution2199723270.040 Why?
Cognition1201467700.040 Why?
Xenopus Proteins119994330.030 Why?
Adult820212140550.030 Why?
Cell Line, Tumor32013166890.030 Why?
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins12015380.030 Why?
Embryo, Nonmammalian119998950.030 Why?
Neuronal Plasticity1200414220.030 Why?
Fluoresceins119952350.030 Why?
Cycloheximide119953470.030 Why?
Dactinomycin119953180.030 Why?
Intracellular Fluid119952030.030 Why?
Oligonucleotide Array Sequence Analysis1200439200.030 Why?
Morphogenesis119997520.030 Why?
Interleukin-1alpha12015840.030 Why?
Insulin1201065800.030 Why?
Xenopus laevis119999570.030 Why?
Lipid Peroxidation119952700.030 Why?
Phosphoserine119952060.030 Why?
Molecular Weight1199722550.030 Why?
Free Radical Scavengers119952160.030 Why?
GTP-Binding Proteins119999700.030 Why?
Body Patterning119996260.030 Why?
Learning1200417130.030 Why?
Rats, Sprague-Dawley2199783010.030 Why?
Enzyme Inhibitors1200537980.030 Why?
Receptors, Amino Acid11993300.030 Why?
Sequence Analysis, RNA1202220120.030 Why?
Phorbol Esters119931110.030 Why?
Models, Biological1201095830.030 Why?
Fluorescent Dyes1200219170.030 Why?
Sequence Deletion1199815260.030 Why?
Diglycerides119931760.030 Why?
Middle Aged420192133830.030 Why?
Immunohistochemistry32003113660.030 Why?
SNARE Proteins12013880.030 Why?
Hydrolysis119946820.030 Why?
Kinetics3199564730.030 Why?
Tetradecanoylphorbol Acetate119938210.030 Why?
Genes, Lethal120132420.030 Why?
Young Adult22021564300.030 Why?
S Phase120134230.030 Why?
Cyclin-Dependent Kinase Inhibitor p16120157050.030 Why?
Huntington Disease1199911240.030 Why?
Organoids120187010.030 Why?
Energy Metabolism2201328990.030 Why?
Organ Specificity1199720080.030 Why?
Enzyme Activation2200037010.030 Why?
Stem Cells1200535670.030 Why?
Nerve Crush12011780.030 Why?
Exons1199824370.030 Why?
Kidney2200571860.030 Why?
Membrane Glycoproteins1200337680.030 Why?
Macaca mulatta1199823750.030 Why?
Chromogranins119921600.020 Why?
Histocytochemistry119927190.020 Why?
Dendritic Spines120132330.020 Why?
Carcinogens119934660.020 Why?
Male620153501180.020 Why?
Genome-Wide Association Study12010122610.020 Why?
Protein Stability120135570.020 Why?
Radiation Tolerance120134860.020 Why?
Phenotype22021163650.020 Why?
Cell Growth Processes120113990.020 Why?
Locomotion120133780.020 Why?
Oxidation-Reduction1199621870.020 Why?
Dose-Response Relationship, Drug21994109430.020 Why?
Optic Nerve Injuries120111500.020 Why?
Behavior, Animal1201818810.020 Why?
Vesicular Transport Proteins120133770.020 Why?
Diabetes Mellitus, Type 211994117250.020 Why?
Rats, Inbred Strains1199121860.020 Why?
GAP-43 Protein119901520.020 Why?
Spinal Cord1201818090.020 Why?
Cerebellum1199714880.020 Why?
Amyotrophic Lateral Sclerosis1200014140.020 Why?
Adrenal Gland Neoplasms319917400.020 Why?
Lipid Metabolism1201818890.020 Why?
Models, Neurological1199817740.020 Why?
Temperature1199522060.020 Why?
Microtubules1199510900.020 Why?
Structure-Activity Relationship1199431290.020 Why?
Restriction Mapping119898780.020 Why?
Specific Pathogen-Free Organisms120082260.020 Why?
Oxidoreductases Acting on Sulfur Group Donors12008320.020 Why?
Fibroblast Growth Factor 2119905990.020 Why?
Optic Nerve120115540.020 Why?
Platelet-Derived Growth Factor119906250.020 Why?
Embryonic Development120137110.020 Why?
Peroxidases120081380.020 Why?
Protein Binding1200093860.020 Why?
Nucleic Acid Hybridization1198913750.020 Why?
Epidermal Growth Factor119907080.020 Why?
Yeasts120082850.020 Why?
Adenosine Triphosphate1199420250.020 Why?
Blotting, Northern1198915810.020 Why?
Microfilament Proteins1201311520.020 Why?
STAT3 Transcription Factor120118730.020 Why?
Sirtuin 1120082460.020 Why?
Cell Count1199118560.020 Why?
Cell Cycle1201529670.020 Why?
BRCA1 Protein1201311490.020 Why?
Tumor Necrosis Factor-alpha1201844200.020 Why?
Oxygen Consumption1201318690.020 Why?
Drug Synergism1199017920.020 Why?
Social Behavior1201311270.020 Why?
Thymus Neoplasms120082680.020 Why?
Brain Chemistry119909810.020 Why?
Immunoblotting1198916820.020 Why?
Retinal Ganglion Cells120117700.020 Why?
Homosexuality119862620.020 Why?
Memory Disorders1201311840.020 Why?
Gene Knockout Techniques120088090.020 Why?
Analysis of Variance1199463650.020 Why?
Tumor Suppressor Protein p531201529480.020 Why?
Mitosis1201012080.020 Why?
Alleles1199669330.020 Why?
Adaptor Proteins, Signal Transducing1201529160.020 Why?
Embryo, Mammalian1199017010.020 Why?
HEK293 Cells1201342040.020 Why?
Cerebral Arteries119864940.010 Why?
Female420133801940.010 Why?
Body Weight1201346690.010 Why?
Dementia1199625180.010 Why?
Nerve Tissue11982790.010 Why?
Biological Transport, Active119823490.010 Why?
Neoplasms12010216830.010 Why?
Embryonic Stem Cells1200812940.010 Why?
Carrier Proteins2200850210.010 Why?
Caspase 1212000110.010 Why?
Infant12002351360.010 Why?
Tunicamycin120001120.010 Why?
Lymphoma1200818770.010 Why?
DNA Methylation1201342860.010 Why?
beta-Transducin Repeat-Containing Proteins11999320.010 Why?
Child, Preschool12002410060.010 Why?
Cytotoxins120001530.010 Why?
Peptides1199144090.010 Why?
Surface Properties1198211840.010 Why?
Glioma1199334010.010 Why?
Intracellular Membranes119793900.010 Why?
Cyclic AMP1198214720.010 Why?
Endoplasmic Reticulum, Smooth1199740.010 Why?
Fluorescent Antibody Technique, Direct11997690.010 Why?
Endocytosis119829850.010 Why?
Precipitin Tests119978290.010 Why?
Mutagenesis1200012660.010 Why?
Glutathione Transferase119975950.010 Why?
Thymus Gland1200012670.010 Why?
Cadherins119999070.010 Why?
Microtubule-Associated Proteins1199910860.010 Why?
Child12002777090.010 Why?
Adolescent12002857810.010 Why?
Time Factors11993400750.010 Why?
Benzoxazines119923010.010 Why?
Oxazines119922980.010 Why?
Recombinant Fusion Proteins1199937720.010 Why?
Macaca fascicularis119929150.010 Why?
Immunoenzyme Techniques1199217990.010 Why?
Necrosis1199216430.000 Why?
Genes1199018930.000 Why?
Gene Expression1199777990.000 Why?
DNA1199773010.000 Why?
Binding, Competitive1198111570.000 Why?
Chick Embryo119819820.000 Why?
Base Sequence11990127970.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.