Harvard Catalyst Profiles

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Bruce Yankner, M.D.,Ph.D.

Concepts (409)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Repressor Proteins7202329861.560 Why?
Amyloid beta-Peptides36202338391.520 Why?
Alzheimer Disease31202385991.330 Why?
Aging20202387081.190 Why?
Neurons32202394631.120 Why?
Amyloid beta-Protein Precursor13201611111.070 Why?
Induced Pluripotent Stem Cells3202318600.740 Why?
Hypothalamus220179990.700 Why?
Caenorhabditis elegans Proteins320228740.610 Why?
Organoids220237400.600 Why?
Longevity3202210650.570 Why?
Amyloid820068410.530 Why?
Brain232023271120.530 Why?
Presenilins12016530.530 Why?
Neural Stem Cells220198880.440 Why?
I-kappa B Kinase220182500.430 Why?
Amnesia120152550.430 Why?
Membrane Proteins14200678560.410 Why?
Stress, Physiological3202114030.410 Why?
Apoptosis11202194860.410 Why?
Oxidative Stress8201431130.400 Why?
Hippocampus10201537660.390 Why?
Nervous System320025450.380 Why?
Neurotoxins320022400.380 Why?
Nerve Degeneration820027480.360 Why?
Neurodegenerative Diseases3201610870.360 Why?
Presenilin-11220086600.350 Why?
Gene Regulatory Networks1201917450.350 Why?
NF-kappa B3201724900.330 Why?
Endopeptidases220057740.330 Why?
tau Proteins5202320950.320 Why?
Transcription Factors42019121280.280 Why?
Cells, Cultured242018189650.280 Why?
Gonadotropin-Releasing Hormone1201311480.280 Why?
Nerve Tissue Proteins6201344140.280 Why?
Peptide Fragments11201851120.280 Why?
Animals5720231684590.280 Why?
Nerve Growth Factors720005640.280 Why?
Presenilin-262008950.270 Why?
Bipolar Disorder1202350920.270 Why?
Astrocytes4201813460.260 Why?
DNA-Binding Proteins3201996060.250 Why?
Cerebral Cortex12200857770.250 Why?
Autophagy4201513260.240 Why?
Neuroprotective Agents320149570.240 Why?
Signal Transduction92017234450.230 Why?
Trans-Activators3200528560.220 Why?
Mice, Transgenic5202395390.220 Why?
Histone Acetyltransferases120053360.220 Why?
Gene Expression Regulation112021119030.210 Why?
Neurofibrillary Tangles420004570.210 Why?
Transfection9200557740.210 Why?
Synapses4200817690.200 Why?
Receptors, Cell Surface5200028220.200 Why?
MicroRNAs2201738160.200 Why?
Mice252023815250.200 Why?
DNA Damage3201524460.190 Why?
Nuclear Proteins4200857960.190 Why?
Amyloid Precursor Protein Secretases420166200.190 Why?
Protein Processing, Post-Translational4200019740.190 Why?
Down Syndrome320029010.180 Why?
Oncogene Proteins120057180.180 Why?
Active Transport, Cell Nucleus120024350.180 Why?
Plaque, Amyloid320007600.170 Why?
Evolution, Molecular1200818860.170 Why?
Parkinson Disease2200528770.170 Why?
Caspases220008790.170 Why?
Rats172008237420.160 Why?
Humans6320237615040.160 Why?
Peptide Hydrolases120026240.160 Why?
Nuclear Lamina12019470.160 Why?
Mice, 129 Strain120193710.160 Why?
Cell Membrane3200536880.160 Why?
Oligonucleotides220215820.160 Why?
Disease Progression22015135060.160 Why?
Congo Red21996480.150 Why?
Gene Expression Profiling3202194200.150 Why?
Protein Precursors3199111320.150 Why?
Cognition Disorders2201039790.140 Why?
Receptor-Interacting Protein Serine-Threonine Kinases120181400.140 Why?
Podocytes120214050.140 Why?
Cell Line132021156010.140 Why?
Mice, Knockout72019144140.130 Why?
Cytoskeletal Proteins2199913420.130 Why?
Mutation82008300520.130 Why?
Calcium2200657220.130 Why?
Axons3201816740.130 Why?
Forkhead Transcription Factors2202216160.130 Why?
Apolipoproteins E2201914440.130 Why?
Spastic Paraplegia, Hereditary119981680.130 Why?
Pheochromocytoma619913280.130 Why?
Neurofibrils11995750.130 Why?
Tumor Cells, Cultured6200261320.120 Why?
In Situ Hybridization, Fluorescence1202125100.120 Why?
RNA-Binding Proteins2201918970.120 Why?
GATA4 Transcription Factor120151240.120 Why?
Dopamine1200216070.120 Why?
Cyclin-Dependent Kinases220106550.120 Why?
Adaptation, Physiological1202113010.120 Why?
Caenorhabditis elegans2202214560.110 Why?
Synucleins220051080.110 Why?
Mitochondria2201036240.110 Why?
Apolipoprotein E4120187080.110 Why?
Cell Differentiation82019115280.110 Why?
RNA, Messenger22008127950.110 Why?
Langerhans Cells119941700.110 Why?
Qc-SNARE Proteins12013200.110 Why?
Single-Cell Analysis2202224490.110 Why?
Species Specificity3200824140.110 Why?
RNA Interference2201928310.110 Why?
Transcription, Genetic3200875940.110 Why?
Prefrontal Cortex1202322190.110 Why?
Cell Death2201416780.110 Why?
CA3 Region, Hippocampal12013540.110 Why?
Exosomes120174240.100 Why?
Ubiquitin-Activating Enzymes12013850.100 Why?
Phagosomes120141990.100 Why?
RNA2202127260.100 Why?
Autistic Disorder1202212200.100 Why?
Cell Nucleus4201429090.100 Why?
Fibroblasts3201941410.100 Why?
Neurogenesis120198630.100 Why?
Neuroglia120189560.100 Why?
Phosphorylation7201883200.100 Why?
DNA Repair3201320450.100 Why?
Ubiquitination2201310060.100 Why?
Lewy Body Disease120142520.090 Why?
Aspartic Acid Endopeptidases220053110.090 Why?
Antioxidants3200816680.090 Why?
Chromatin Immunoprecipitation120148550.090 Why?
Islet Amyloid Polypeptide31996420.090 Why?
Frontotemporal Dementia120142470.090 Why?
Suppressor of Cytokine Signaling Proteins120111780.090 Why?
Histone Demethylases120133200.090 Why?
Solubility3200010910.090 Why?
Tachykinins11990770.090 Why?
Protein Transport1201619670.090 Why?
Cell Survival4202157910.090 Why?
Substance P119913350.090 Why?
Synaptic Transmission3201811730.090 Why?
Reactive Oxygen Species2201021410.090 Why?
Mice, Inbred C57BL62019221690.080 Why?
Aged, 80 and over72021589760.080 Why?
Protein Structure, Tertiary3201337920.080 Why?
Protein Kinase C1199312020.080 Why?
Phosphoproteins3201824480.080 Why?
Inflammation22015107730.080 Why?
HeLa Cells4201330930.080 Why?
Peroxiredoxins12008510.080 Why?
Cell Adhesion2199230870.070 Why?
PC12 Cells320003170.070 Why?
Amino Acids1199317180.070 Why?
alpha-Synuclein220057500.070 Why?
Ubiquitin-Protein Ligases2201318970.070 Why?
Dendrites119904750.070 Why?
Receptor, Notch1220004960.070 Why?
Proteins4200860320.070 Why?
Thioredoxins120082020.070 Why?
Down-Regulation1201429190.070 Why?
Transcriptional Activation2200517560.070 Why?
Fetus3200218630.070 Why?
Subcellular Fractions220055320.070 Why?
Cerebral Arterial Diseases11986820.070 Why?
Disease Models, Animal22023182520.070 Why?
Gene Expression Regulation, Developmental1199736120.060 Why?
Epitopes2199725030.060 Why?
Sirtuins120083200.060 Why?
Nerve Regeneration120117950.060 Why?
PTEN Phosphohydrolase1201111150.060 Why?
Octamer Transcription Factors12005180.060 Why?
Nuclear Matrix-Associated Proteins12005380.060 Why?
Amygdala1201313540.060 Why?
Up-Regulation1201441240.060 Why?
Aged820211692890.060 Why?
Heparin1199216340.060 Why?
Genomic Instability120087090.060 Why?
Golgi Apparatus219984050.060 Why?
Granuloma119863280.060 Why?
Phosphatidylinositol 3-Kinases2201028650.060 Why?
Copper120063690.060 Why?
Cats219969750.060 Why?
Histones1201325800.050 Why?
Endoplasmic Reticulum2200011340.050 Why?
Antibodies1199124180.050 Why?
Adult920232211770.050 Why?
Biological Transport3199920910.050 Why?
Neurites219973910.050 Why?
Receptors, N-Methyl-D-Aspartate120088940.050 Why?
Carbonyl Cyanide m-Chlorophenyl Hydrazone12002220.050 Why?
Gene Deletion2200026650.050 Why?
Blotting, Western2200850350.050 Why?
Uncoupling Agents12002460.050 Why?
Genes, Recessive120056230.050 Why?
Vasculitis119865210.050 Why?
Insulin-Like Growth Factor I1201019340.050 Why?
Zinc120066900.050 Why?
Purines120056070.050 Why?
Nervous System Diseases1199216660.050 Why?
Carbocyanines120021750.050 Why?
Homeostasis2202133230.050 Why?
RNA, Small Interfering2201334290.050 Why?
14-3-3 Proteins120022200.050 Why?
Tyrosine 3-Monooxygenase120023700.050 Why?
Fluorescent Antibody Technique1200524690.050 Why?
Genes, Reporter1200515290.050 Why?
In Situ Nick-End Labeling120026130.050 Why?
Phylogeny1200828110.050 Why?
Recombinant Proteins4200265340.050 Why?
Sclerosis120212100.050 Why?
Chromosomes, Human, Pair 16120223430.050 Why?
Apoptosis Regulatory Proteins1200611350.040 Why?
Receptors, Notch120057430.040 Why?
Calcium-Calmodulin-Dependent Protein Kinases219994890.040 Why?
Substantia Nigra120023500.040 Why?
Intracellular Signaling Peptides and Proteins2201328720.040 Why?
Glycogen Synthase Kinase 3219994110.040 Why?
Microglia2201813610.040 Why?
Biopolymers120001840.040 Why?
Chromosome Disorders120224970.040 Why?
Microscopy, Confocal1200519710.040 Why?
Microscopy, Fluorescence2199826450.040 Why?
HIV1198615820.040 Why?
Molecular Sequence Data52008176350.040 Why?
Promoter Regions, Genetic2201557890.040 Why?
Receptors, Drug119791570.040 Why?
Islets of Langerhans2199613410.040 Why?
Protease Inhibitors219937540.040 Why?
Male720233608040.040 Why?
Callithrix11998940.040 Why?
Cytoskeleton2202111700.040 Why?
Apolipoprotein E3120181070.040 Why?
Nuclear Envelope119791630.040 Why?
Superoxide Dismutase120005940.040 Why?
Adenomatous Polyposis Coli Protein119981810.040 Why?
Staurosporine120182420.040 Why?
Chromosome Deletion1202213860.040 Why?
Diabetes Mellitus1199658400.040 Why?
Albuminuria120216570.040 Why?
Receptors, Nerve Growth Factor319901980.030 Why?
Amino Acid Sequence41993134460.030 Why?
Chromatin1200829600.030 Why?
Tissue Distribution2199722650.030 Why?
beta Catenin2199910400.030 Why?
DNA Breaks, Double-Stranded220136120.030 Why?
Benzimidazoles120028580.030 Why?
Epigenesis, Genetic1201038020.030 Why?
Cognition1201469900.030 Why?
Xenopus Proteins119994340.030 Why?
Cell Line, Tumor32013169810.030 Why?
Lysosomes220109240.030 Why?
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins12015440.030 Why?
Oligonucleotide Array Sequence Analysis1200437780.030 Why?
Embryo, Nonmammalian119999060.030 Why?
Neuronal Plasticity1200414360.030 Why?
Dactinomycin119953040.030 Why?
Fluoresceins119952350.030 Why?
Cycloheximide119953430.030 Why?
Intracellular Fluid119952010.030 Why?
Insulin1201065960.030 Why?
Morphogenesis119997410.030 Why?
Interleukin-1alpha12015860.030 Why?
Xenopus laevis119999630.030 Why?
Molecular Weight1199721860.030 Why?
Free Radical Scavengers119952110.030 Why?
Lipid Peroxidation119952710.030 Why?
Phosphoserine119952030.030 Why?
GTP-Binding Proteins119999510.030 Why?
Body Patterning119996320.030 Why?
Enzyme Inhibitors1200537120.030 Why?
Learning1200417400.030 Why?
Rats, Sprague-Dawley2199781810.030 Why?
Sequence Analysis, RNA1202220200.030 Why?
Models, Biological1201094690.030 Why?
Receptors, Amino Acid11993300.030 Why?
Phorbol Esters119931080.030 Why?
Fluorescent Dyes1200219030.030 Why?
Sequence Deletion1199814940.030 Why?
Female520233926440.030 Why?
Diglycerides119931770.030 Why?
SNARE Proteins12013810.030 Why?
Immunohistochemistry32003110760.030 Why?
Hydrolysis119946640.030 Why?
Kinetics3199563740.030 Why?
Middle Aged420192208950.030 Why?
Genes, Lethal120132230.030 Why?
Tetradecanoylphorbol Acetate119938170.030 Why?
S Phase120134210.030 Why?
Stem Cells1200535220.030 Why?
Enzyme Activation2200035970.030 Why?
Energy Metabolism2201328820.030 Why?
Organ Specificity1199719670.030 Why?
Cyclin-Dependent Kinase Inhibitor p16120156980.030 Why?
Huntington Disease1199911440.030 Why?
Young Adult22021592430.030 Why?
Kidney2200570480.020 Why?
Membrane Glycoproteins1200337020.020 Why?
Exons1199823910.020 Why?
Nerve Crush12011770.020 Why?
Macaca mulatta1199823290.020 Why?
Carcinogens119934520.020 Why?
Chromogranins119921610.020 Why?
Histocytochemistry119926980.020 Why?
Radiation Tolerance120134790.020 Why?
Dendritic Spines120132430.020 Why?
Protein Stability120135780.020 Why?
Cell Growth Processes120113840.020 Why?
Genome-Wide Association Study12010126900.020 Why?
Phenotype22021165910.020 Why?
Dose-Response Relationship, Drug21994107660.020 Why?
Locomotion120133880.020 Why?
Optic Nerve Injuries120111500.020 Why?
Behavior, Animal1201818780.020 Why?
Vesicular Transport Proteins120133760.020 Why?
Rats, Inbred Strains1199120880.020 Why?
Spinal Cord1201818180.020 Why?
GAP-43 Protein119901520.020 Why?
Adrenal Gland Neoplasms319917320.020 Why?
Diabetes Mellitus, Type 211994121480.020 Why?
Oxidation-Reduction1199622310.020 Why?
Cerebellum1199715010.020 Why?
Models, Neurological1199817670.020 Why?
Amyotrophic Lateral Sclerosis1200014690.020 Why?
Lipid Metabolism1201819020.020 Why?
Microtubules1199510740.020 Why?
Structure-Activity Relationship1199430760.020 Why?
Temperature1199522260.020 Why?
Restriction Mapping119898510.020 Why?
Specific Pathogen-Free Organisms120082210.020 Why?
Oxidoreductases Acting on Sulfur Group Donors12008320.020 Why?
Fibroblast Growth Factor 2119905920.020 Why?
Platelet-Derived Growth Factor119906180.020 Why?
Optic Nerve120115720.020 Why?
Embryonic Development120137210.020 Why?
Peroxidases120081340.020 Why?
Nucleic Acid Hybridization1198913020.020 Why?
Adenosine Triphosphate1199419890.020 Why?
Epidermal Growth Factor119907010.020 Why?
Protein Binding1200093510.020 Why?
Yeasts120082790.020 Why?
Blotting, Northern1198915450.020 Why?
Microfilament Proteins1201311340.020 Why?
Sirtuin 1120082460.020 Why?
STAT3 Transcription Factor120118710.020 Why?
Cell Count1199118350.020 Why?
Cell Cycle1201529320.020 Why?
Tumor Necrosis Factor-alpha1201843520.020 Why?
BRCA1 Protein1201311550.020 Why?
Oxygen Consumption1201318660.020 Why?
Drug Synergism1199017550.020 Why?
Social Behavior1201311350.020 Why?
Brain Chemistry119909600.020 Why?
Immunoblotting1198916460.020 Why?
Thymus Neoplasms120082740.020 Why?
Homosexuality119862670.020 Why?
Memory Disorders1201311980.020 Why?
Gene Knockout Techniques120088020.020 Why?
Retinal Ganglion Cells120118110.020 Why?
Analysis of Variance1199462280.020 Why?
Tumor Suppressor Protein p531201529170.020 Why?
Mitosis1201011870.020 Why?
Adaptor Proteins, Signal Transducing1201528980.020 Why?
Alleles1199668630.020 Why?
Embryo, Mammalian1199016750.010 Why?
HEK293 Cells1201342780.010 Why?
Cerebral Arteries119864900.010 Why?
Body Weight1201346180.010 Why?
Nerve Tissue11982780.010 Why?
Biological Transport, Active119823280.010 Why?
Neoplasms12010221700.010 Why?
Dementia1199626860.010 Why?
Embryonic Stem Cells1200812630.010 Why?
Carrier Proteins2200849360.010 Why?
Caspase 121200080.010 Why?
Tunicamycin120001080.010 Why?
Infant12002361920.010 Why?
beta-Transducin Repeat-Containing Proteins11999320.010 Why?
Lymphoma1200819010.010 Why?
DNA Methylation1201343980.010 Why?
Peptides1199143580.010 Why?
Cytotoxins120001530.010 Why?
Child, Preschool12002422300.010 Why?
Surface Properties1198211610.010 Why?
Glioma1199334550.010 Why?
Intracellular Membranes119793890.010 Why?
Cyclic AMP1198214630.010 Why?
Endoplasmic Reticulum, Smooth1199730.010 Why?
Endocytosis119829570.010 Why?
Fluorescent Antibody Technique, Direct11997660.010 Why?
Precipitin Tests119978140.010 Why?
Mutagenesis1200012320.010 Why?
Glutathione Transferase119975650.010 Why?
Thymus Gland1200012430.010 Why?
Cadherins119999030.010 Why?
Microtubule-Associated Proteins1199910760.010 Why?
Child12002801530.010 Why?
Adolescent12002883190.010 Why?
Time Factors11993399670.010 Why?
Benzoxazines119923160.010 Why?
Recombinant Fusion Proteins1199937340.010 Why?
Macaca fascicularis119929030.010 Why?
Oxazines119923500.010 Why?
Immunoenzyme Techniques1199217050.010 Why?
Necrosis1199216110.000 Why?
Genes1199018230.000 Why?
Gene Expression1199775810.000 Why?
DNA1199772120.000 Why?
Binding, Competitive1198111410.000 Why?
Chick Embryo119819820.000 Why?
Base Sequence11990124410.000 Why?
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Concepts (409)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.