Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Bruce Yankner, M.D.,Ph.D.

Concepts (409)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Repressor Proteins7202329741.550 Why?
Amyloid beta-Peptides36202338921.490 Why?
Alzheimer Disease31202387241.310 Why?
Aging20202387231.180 Why?
Neurons32202395211.100 Why?
Amyloid beta-Protein Precursor13201611161.060 Why?
Induced Pluripotent Stem Cells3202318840.720 Why?
Hypothalamus2201710020.690 Why?
Caenorhabditis elegans Proteins320228830.600 Why?
Organoids220237400.590 Why?
Longevity3202210850.560 Why?
Amyloid820068480.520 Why?
Brain232023271770.520 Why?
Presenilins12016510.520 Why?
Neural Stem Cells220198970.440 Why?
I-kappa B Kinase220182500.420 Why?
Amnesia120152570.420 Why?
Membrane Proteins14200678500.410 Why?
Stress, Physiological3202114050.400 Why?
Apoptosis11202195080.400 Why?
Oxidative Stress8201431400.390 Why?
Hippocampus10201537730.380 Why?
Nervous System320025420.380 Why?
Neurotoxins320022400.370 Why?
Nerve Degeneration820027480.360 Why?
Neurodegenerative Diseases3201610880.350 Why?
Presenilin-11220086650.340 Why?
Gene Regulatory Networks1201917500.340 Why?
NF-kappa B3201724950.330 Why?
Endopeptidases220057600.320 Why?
tau Proteins5202321100.310 Why?
Transcription Factors42019121300.280 Why?
Cells, Cultured242018189670.280 Why?
Gonadotropin-Releasing Hormone1201311420.280 Why?
Nerve Tissue Proteins6201343990.280 Why?
Peptide Fragments11201851260.280 Why?
Animals5720231688000.280 Why?
Nerve Growth Factors720005640.270 Why?
Bipolar Disorder1202351280.260 Why?
Presenilin-2620081000.260 Why?
Astrocytes4201813530.260 Why?
DNA-Binding Proteins3201996010.250 Why?
Cerebral Cortex12200857580.250 Why?
Autophagy4201513490.230 Why?
Neuroprotective Agents320149590.230 Why?
Trans-Activators3200528490.220 Why?
Signal Transduction92017236050.220 Why?
Mice, Transgenic5202395400.220 Why?
Histone Acetyltransferases120053320.210 Why?
Gene Expression Regulation112021119060.210 Why?
Neurofibrillary Tangles420004570.210 Why?
Transfection9200557390.200 Why?
Synapses4200817590.200 Why?
MicroRNAs2201737870.200 Why?
Receptors, Cell Surface5200028150.200 Why?
Mice252023818390.190 Why?
DNA Damage3201524630.190 Why?
Nuclear Proteins4200857910.190 Why?
Amyloid Precursor Protein Secretases420166170.190 Why?
Protein Processing, Post-Translational4200019620.190 Why?
Down Syndrome320029150.180 Why?
Oncogene Proteins120057110.180 Why?
Active Transport, Cell Nucleus120024310.180 Why?
Plaque, Amyloid320007700.170 Why?
Evolution, Molecular1200818890.170 Why?
Parkinson Disease2200528850.160 Why?
Rats172008237170.160 Why?
Caspases220008810.160 Why?
Peptide Hydrolases120026080.160 Why?
Humans6320237661170.160 Why?
Nuclear Lamina12019470.160 Why?
Oligonucleotides220215610.160 Why?
Cell Membrane3200536350.160 Why?
Mice, 129 Strain120193680.160 Why?
Disease Progression22015136160.150 Why?
Congo Red21996490.150 Why?
Gene Expression Profiling3202195270.140 Why?
Protein Precursors3199111330.140 Why?
Cognition Disorders2201039660.140 Why?
Receptor-Interacting Protein Serine-Threonine Kinases120181460.140 Why?
Podocytes120213890.140 Why?
Cell Line132021155460.130 Why?
Mice, Knockout72019144560.130 Why?
Cytoskeletal Proteins2199913220.130 Why?
Mutation82008302090.130 Why?
Axons3201816770.130 Why?
Calcium2200657700.130 Why?
Forkhead Transcription Factors2202216230.130 Why?
Apolipoproteins E2201914590.130 Why?
Pheochromocytoma619913260.120 Why?
Spastic Paraplegia, Hereditary119981710.120 Why?
Tumor Cells, Cultured6200261020.120 Why?
Neurofibrils11995750.120 Why?
RNA-Binding Proteins2201918830.120 Why?
In Situ Hybridization, Fluorescence1202125100.120 Why?
Dopamine1200215820.120 Why?
GATA4 Transcription Factor120151250.120 Why?
Cyclin-Dependent Kinases220106590.110 Why?
Adaptation, Physiological1202113100.110 Why?
Caenorhabditis elegans2202214760.110 Why?
Synucleins220051080.110 Why?
Apolipoprotein E4120187070.110 Why?
RNA, Messenger22008127750.110 Why?
Mitochondria2201036720.110 Why?
Cell Differentiation82019116420.110 Why?
Langerhans Cells119941690.110 Why?
Qc-SNARE Proteins12013210.110 Why?
RNA Interference2201928280.110 Why?
Species Specificity3200824060.100 Why?
Transcription, Genetic3200876000.100 Why?
Prefrontal Cortex1202322240.100 Why?
Single-Cell Analysis2202225360.100 Why?
Cell Death2201416760.100 Why?
Exosomes120174170.100 Why?
CA3 Region, Hippocampal12013540.100 Why?
Phagosomes120141930.100 Why?
Ubiquitin-Activating Enzymes12013850.100 Why?
RNA2202127160.100 Why?
Cell Nucleus4201428640.100 Why?
Autistic Disorder1202212380.100 Why?
Fibroblasts3201941620.100 Why?
Neurogenesis120198640.100 Why?
Neuroglia120189630.100 Why?
Phosphorylation7201882920.100 Why?
DNA Repair3201320480.100 Why?
Ubiquitination2201310000.090 Why?
Lewy Body Disease120142520.090 Why?
Aspartic Acid Endopeptidases220053080.090 Why?
Antioxidants3200816710.090 Why?
Chromatin Immunoprecipitation120148560.090 Why?
Islet Amyloid Polypeptide31996410.090 Why?
Frontotemporal Dementia120142480.090 Why?
Suppressor of Cytokine Signaling Proteins120111780.090 Why?
Histone Demethylases120133280.090 Why?
Solubility3200010770.090 Why?
Protein Transport1201619390.090 Why?
Tachykinins11990780.090 Why?
Cell Survival4202157470.090 Why?
Substance P119913310.090 Why?
Synaptic Transmission3201811750.090 Why?
Reactive Oxygen Species2201021440.080 Why?
Mice, Inbred C57BL62019223410.080 Why?
Aged, 80 and over72021595150.080 Why?
Protein Structure, Tertiary3201337510.080 Why?
Protein Kinase C1199312050.080 Why?
Phosphoproteins3201824450.080 Why?
HeLa Cells4201330730.080 Why?
Inflammation22015108600.080 Why?
Peroxiredoxins12008500.070 Why?
Cell Adhesion2199230890.070 Why?
PC12 Cells320003160.070 Why?
Amino Acids1199317100.070 Why?
Ubiquitin-Protein Ligases2201318970.070 Why?
Dendrites119904690.070 Why?
alpha-Synuclein220057710.070 Why?
Proteins4200859950.070 Why?
Receptor, Notch1220005160.070 Why?
Thioredoxins120082020.070 Why?
Down-Regulation1201429270.070 Why?
Transcriptional Activation2200517430.070 Why?
Subcellular Fractions220055280.070 Why?
Fetus3200218780.070 Why?
Cerebral Arterial Diseases11986820.070 Why?
Disease Models, Animal22023183210.060 Why?
Gene Expression Regulation, Developmental1199736060.060 Why?
Epitopes2199725230.060 Why?
Nerve Regeneration120118000.060 Why?
PTEN Phosphohydrolase1201111170.060 Why?
Sirtuins120083230.060 Why?
Octamer Transcription Factors12005180.060 Why?
Nuclear Matrix-Associated Proteins12005380.060 Why?
Amygdala1201313760.060 Why?
Up-Regulation1201441330.060 Why?
Aged820211712190.060 Why?
Heparin1199216350.060 Why?
Genomic Instability120087160.060 Why?
Golgi Apparatus219984050.060 Why?
Granuloma119863290.060 Why?
Phosphatidylinositol 3-Kinases2201028770.060 Why?
Copper120063650.060 Why?
Cats219969720.050 Why?
Histones1201325910.050 Why?
Endoplasmic Reticulum2200011320.050 Why?
Antibodies1199124150.050 Why?
Biological Transport3199920800.050 Why?
Adult920232231390.050 Why?
Neurites219973890.050 Why?
Receptors, N-Methyl-D-Aspartate120089040.050 Why?
Gene Deletion2200026670.050 Why?
Blotting, Western2200850200.050 Why?
Carbonyl Cyanide m-Chlorophenyl Hydrazone12002220.050 Why?
Genes, Recessive120056250.050 Why?
Uncoupling Agents12002460.050 Why?
Insulin-Like Growth Factor I1201019350.050 Why?
Zinc120066750.050 Why?
Vasculitis119865280.050 Why?
Purines120056160.050 Why?
Nervous System Diseases1199216570.050 Why?
Carbocyanines120021770.050 Why?
Homeostasis2202133380.050 Why?
RNA, Small Interfering2201334240.050 Why?
14-3-3 Proteins120022210.050 Why?
Tyrosine 3-Monooxygenase120023670.050 Why?
Fluorescent Antibody Technique1200524690.050 Why?
Genes, Reporter1200515240.050 Why?
Recombinant Proteins4200264930.040 Why?
In Situ Nick-End Labeling120026100.040 Why?
Phylogeny1200828380.040 Why?
Sclerosis120212110.040 Why?
Chromosomes, Human, Pair 16120223400.040 Why?
Receptors, Notch120057510.040 Why?
Apoptosis Regulatory Proteins1200611500.040 Why?
Calcium-Calmodulin-Dependent Protein Kinases219994890.040 Why?
Substantia Nigra120023460.040 Why?
Intracellular Signaling Peptides and Proteins2201328790.040 Why?
Glycogen Synthase Kinase 3219994140.040 Why?
Biopolymers120001810.040 Why?
Microscopy, Confocal1200519670.040 Why?
Chromosome Disorders120224980.040 Why?
Microglia2201813710.040 Why?
Microscopy, Fluorescence2199826270.040 Why?
HIV1198615870.040 Why?
Molecular Sequence Data52008175970.040 Why?
Promoter Regions, Genetic2201557840.040 Why?
Receptors, Drug119791560.040 Why?
Islets of Langerhans2199613490.040 Why?
Protease Inhibitors219937500.040 Why?
Male720233639350.040 Why?
Callithrix11998950.040 Why?
Apolipoprotein E3120181040.040 Why?
Cytoskeleton2202111790.040 Why?
Nuclear Envelope119791610.040 Why?
Superoxide Dismutase120005930.040 Why?
Adenomatous Polyposis Coli Protein119981820.040 Why?
Staurosporine120182400.040 Why?
Chromosome Deletion1202213840.040 Why?
Diabetes Mellitus1199658890.040 Why?
Albuminuria120216590.030 Why?
Amino Acid Sequence41993134000.030 Why?
Receptors, Nerve Growth Factor319901990.030 Why?
Chromatin1200829810.030 Why?
beta Catenin2199910470.030 Why?
Tissue Distribution2199722710.030 Why?
DNA Breaks, Double-Stranded220136050.030 Why?
Benzimidazoles120028620.030 Why?
Epigenesis, Genetic1201038180.030 Why?
Cognition1201470500.030 Why?
Xenopus Proteins119994330.030 Why?
Cell Line, Tumor32013170710.030 Why?
Lysosomes220109320.030 Why?
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins12015430.030 Why?
Oligonucleotide Array Sequence Analysis1200437960.030 Why?
Embryo, Nonmammalian119999100.030 Why?
Neuronal Plasticity1200414470.030 Why?
Dactinomycin119953040.030 Why?
Fluoresceins119952350.030 Why?
Cycloheximide119953390.030 Why?
Intracellular Fluid119952010.030 Why?
Insulin1201066040.030 Why?
Morphogenesis119997430.030 Why?
Interleukin-1alpha12015880.030 Why?
Xenopus laevis119999650.030 Why?
Molecular Weight1199721610.030 Why?
GTP-Binding Proteins119999450.030 Why?
Phosphoserine119952030.030 Why?
Free Radical Scavengers119952130.030 Why?
Lipid Peroxidation119952750.030 Why?
Enzyme Inhibitors1200537220.030 Why?
Body Patterning119996330.030 Why?
Learning1200417550.030 Why?
Rats, Sprague-Dawley2199781130.030 Why?
Models, Biological1201094450.030 Why?
Sequence Analysis, RNA1202220390.030 Why?
Receptors, Amino Acid11993300.030 Why?
Phorbol Esters119931080.030 Why?
Fluorescent Dyes1200219280.030 Why?
Sequence Deletion1199814940.030 Why?
Female520233962330.030 Why?
Diglycerides119931740.030 Why?
Immunohistochemistry32003110350.030 Why?
Hydrolysis119946430.030 Why?
SNARE Proteins12013800.030 Why?
Kinetics3199562730.030 Why?
Middle Aged420192230830.030 Why?
Genes, Lethal120132240.030 Why?
Tetradecanoylphorbol Acetate119938220.030 Why?
Enzyme Activation2200035840.030 Why?
S Phase120134230.030 Why?
Stem Cells1200535370.030 Why?
Energy Metabolism2201328940.020 Why?
Organ Specificity1199719660.020 Why?
Cyclin-Dependent Kinase Inhibitor p16120157020.020 Why?
Huntington Disease1199911470.020 Why?
Membrane Glycoproteins1200336920.020 Why?
Young Adult22021598680.020 Why?
Kidney2200570720.020 Why?
Exons1199823930.020 Why?
Nerve Crush12011770.020 Why?
Macaca mulatta1199823410.020 Why?
Carcinogens119934510.020 Why?
Chromogranins119921590.020 Why?
Histocytochemistry119926950.020 Why?
Radiation Tolerance120134750.020 Why?
Dendritic Spines120132440.020 Why?
Protein Stability120135760.020 Why?
Cell Growth Processes120113800.020 Why?
Genome-Wide Association Study12010128030.020 Why?
Dose-Response Relationship, Drug21994107370.020 Why?
Phenotype22021167160.020 Why?
Behavior, Animal1201818670.020 Why?
Locomotion120133840.020 Why?
Optic Nerve Injuries120111500.020 Why?
Spinal Cord1201818110.020 Why?
Vesicular Transport Proteins120133760.020 Why?
Rats, Inbred Strains1199120770.020 Why?
GAP-43 Protein119901520.020 Why?
Oxidation-Reduction1199622210.020 Why?
Adrenal Gland Neoplasms319917310.020 Why?
Diabetes Mellitus, Type 211994122350.020 Why?
Models, Neurological1199817460.020 Why?
Cerebellum1199715190.020 Why?
Lipid Metabolism1201818930.020 Why?
Amyotrophic Lateral Sclerosis1200014820.020 Why?
Microtubules1199510640.020 Why?
Structure-Activity Relationship1199430510.020 Why?
Temperature1199522270.020 Why?
Restriction Mapping119898480.020 Why?
Specific Pathogen-Free Organisms120082200.020 Why?
Fibroblast Growth Factor 2119905900.020 Why?
Oxidoreductases Acting on Sulfur Group Donors12008320.020 Why?
Platelet-Derived Growth Factor119906140.020 Why?
Optic Nerve120115680.020 Why?
Embryonic Development120137190.020 Why?
Peroxidases120081340.020 Why?
Protein Binding1200093010.020 Why?
Adenosine Triphosphate1199420030.020 Why?
Epidermal Growth Factor119906970.020 Why?
Nucleic Acid Hybridization1198913050.020 Why?
Microfilament Proteins1201311300.020 Why?
Yeasts120082780.020 Why?
Blotting, Northern1198915460.020 Why?
STAT3 Transcription Factor120118720.020 Why?
Cell Count1199118250.020 Why?
Cell Cycle1201529200.020 Why?
Sirtuin 1120082470.020 Why?
Tumor Necrosis Factor-alpha1201843420.020 Why?
BRCA1 Protein1201311550.020 Why?
Oxygen Consumption1201318720.020 Why?
Drug Synergism1199017540.020 Why?
Social Behavior1201311430.020 Why?
Brain Chemistry119909510.020 Why?
Immunoblotting1198916440.020 Why?
Thymus Neoplasms120082710.020 Why?
Memory Disorders1201311930.020 Why?
Homosexuality119862680.020 Why?
Gene Knockout Techniques120088000.020 Why?
Retinal Ganglion Cells120118080.020 Why?
Analysis of Variance1199462080.020 Why?
Adaptor Proteins, Signal Transducing1201528980.010 Why?
Mitosis1201011750.010 Why?
Tumor Suppressor Protein p531201529460.010 Why?
Alleles1199668920.010 Why?
Embryo, Mammalian1199016740.010 Why?
HEK293 Cells1201342630.010 Why?
Cerebral Arteries119864900.010 Why?
Body Weight1201346260.010 Why?
Nerve Tissue11982780.010 Why?
Biological Transport, Active119823230.010 Why?
Embryonic Stem Cells1200812420.010 Why?
Neoplasms12010223440.010 Why?
Dementia1199627410.010 Why?
Carrier Proteins2200849100.010 Why?
Caspase 121200080.010 Why?
Tunicamycin120001080.010 Why?
Infant12002364270.010 Why?
Lymphoma1200818960.010 Why?
Peptides1199143380.010 Why?
beta-Transducin Repeat-Containing Proteins11999330.010 Why?
DNA Methylation1201344250.010 Why?
Cytotoxins120001540.010 Why?
Child, Preschool12002425110.010 Why?
Surface Properties1198211520.010 Why?
Glioma1199334910.010 Why?
Intracellular Membranes119793860.010 Why?
Cyclic AMP1198214670.010 Why?
Endoplasmic Reticulum, Smooth1199740.010 Why?
Endocytosis119829520.010 Why?
Fluorescent Antibody Technique, Direct11997650.010 Why?
Precipitin Tests119978120.010 Why?
Mutagenesis1200012270.010 Why?
Glutathione Transferase119975630.010 Why?
Thymus Gland1200012590.010 Why?
Cadherins119999000.010 Why?
Microtubule-Associated Proteins1199910680.010 Why?
Child12002805730.010 Why?
Adolescent12002888190.010 Why?
Time Factors11993401080.010 Why?
Benzoxazines119923200.010 Why?
Recombinant Fusion Proteins1199937330.010 Why?
Macaca fascicularis119929080.010 Why?
Oxazines119923580.010 Why?
Immunoenzyme Techniques1199216950.010 Why?
Necrosis1199216140.000 Why?
Genes1199018240.000 Why?
Gene Expression1199775820.000 Why?
DNA1199771930.000 Why?
Binding, Competitive1198111400.000 Why?
Chick Embryo119819640.000 Why?
Base Sequence11990124050.000 Why?
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Concepts (409)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.