Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Frances Lowe Arnold, Ph.D.

Concepts (512)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Directed Molecular Evolution5120131618.340 Why?
Protein Engineering5720135417.720 Why?
Cytochrome P-450 Enzyme System4220134197.590 Why?
Recombination, Genetic37201215864.350 Why?
Enzymes1920132663.080 Why?
Evolution, Molecular23201219372.410 Why?
Mixed Function Oxygenases1520102722.380 Why?
Escherichia coli46201342142.230 Why?
Proteins34201260962.140 Why?
Bacillus megaterium122012201.820 Why?
Mutagenesis32201212631.670 Why?
Subtilisins142001831.630 Why?
Recombinant Fusion Proteins19201237701.560 Why?
Enzyme Stability2920102101.550 Why?
Bacterial Proteins27201338431.460 Why?
Models, Molecular49201254541.410 Why?
Gene Library14201310761.270 Why?
Cellulases32012101.250 Why?
Catalysis2620127601.210 Why?
Cellulose 1,4-beta-Cellobiosidase3201281.190 Why?
Mutagenesis, Site-Directed22201217231.180 Why?
Carotenoids620066241.100 Why?
Oxygenases52002601.000 Why?
NADPH-Ferrihemoprotein Reductase142013310.950 Why?
Protein Folding1220128430.900 Why?
Recombinant Proteins25201266080.900 Why?
Propane42010110.900 Why?
Cellulase32011120.900 Why?
Temperature21201222070.870 Why?
Substrate Specificity20201018020.860 Why?
Protein Conformation29201240130.850 Why?
Butanols22012190.840 Why?
Hydroxylation1320121410.840 Why?
Fungal Proteins520129120.830 Why?
Biotechnology920012780.820 Why?
beta-Lactamases820123030.820 Why?
Genetic Engineering920119520.770 Why?
Carboxylic Ester Hydrolases72003980.750 Why?
Polymerase Chain Reaction22201361710.720 Why?
Metals1019977170.710 Why?
Alkanes32012440.710 Why?
NADP620122250.710 Why?
Protein Stability620135560.690 Why?
Alkenes22012570.680 Why?
Models, Chemical720126260.680 Why?
Fungi320113270.670 Why?
Horseradish Peroxidase520011660.640 Why?
Bacillus subtilis820003590.640 Why?
Colorimetry320041470.640 Why?
Oxidoreductases720064240.610 Why?
Thermodynamics1220105940.600 Why?
Peptide Library820103500.600 Why?
Clostridium22012980.590 Why?
Histidine1019973130.580 Why?
Oxidation-Reduction15201221870.580 Why?
Subtilisin32001120.580 Why?
Saccharomyces cerevisiae11201027490.580 Why?
Cytochrome c Group819961280.570 Why?
Kinetics21200964740.560 Why?
Plasmids14200823050.550 Why?
Chelating Agents1020043800.550 Why?
Mutation292012297170.520 Why?
Farnesyl-Diphosphate Farnesyltransferase3200450.520 Why?
Glycoside Hydrolases220121350.520 Why?
Catalytic Domain820126990.510 Why?
Biofilms320116130.510 Why?
Amino Acids5201017270.490 Why?
Heme820133070.460 Why?
Aldehydes220121670.450 Why?
DNA, Recombinant720034750.450 Why?
Monosaccharides22010700.440 Why?
Methane12012510.440 Why?
Alkyl and Aryl Transferases22003890.440 Why?
Lactococcus lactis12012280.430 Why?
Galactose Oxidase22002140.430 Why?
Binding Sites18200961150.420 Why?
Solvents820043020.420 Why?
Biofuels22011410.420 Why?
Stereoisomerism720126250.410 Why?
Combinatorial Chemistry Techniques220101290.410 Why?
Alcohol Oxidoreductases120121700.410 Why?
Drug Evaluation, Preclinical3200213720.410 Why?
Ketol-Acid Reductoisomerase1201110.410 Why?
Copper919973660.400 Why?
Chromatography, Affinity619965490.400 Why?
Amino Acid Substitution8200817920.400 Why?
Clostridium thermocellum1201020.400 Why?
Clostridium cellulolyticum1201020.400 Why?
Cyclopropanes120124160.390 Why?
Amino Acid Sequence192012138140.390 Why?
Actinomycetales12010310.390 Why?
Hydrogen220101640.380 Why?
Hot Temperature10201013550.380 Why?
Carbon320106860.380 Why?
Alcohol Dehydrogenase120111190.380 Why?
Point Mutation8200216240.380 Why?
Selection, Genetic620109140.360 Why?
Protein Structure, Tertiary12201138470.350 Why?
Protein Biosynthesis3200521260.340 Why?
Methionine220035900.340 Why?
Cloning, Molecular11200743220.340 Why?
Butanes1200870.340 Why?
DNA12200372890.340 Why?
Erwinia32004230.340 Why?
Oxidoreductases, N-Demethylating120091150.340 Why?
Dimethylformamide51996210.340 Why?
Protein Structure, Secondary7200812450.340 Why?
Industrial Microbiology1200860.330 Why?
DNA Primers7200628920.330 Why?
Alanine120105720.320 Why?
Biotransformation420101680.320 Why?
Symbiosis120112830.320 Why?
Dopamine3201315890.320 Why?
Genes, Bacterial6200610780.310 Why?
Serotonin1201210240.300 Why?
Models, Genetic8201034930.300 Why?
Cytochromes c319941800.300 Why?
Quorum Sensing120071310.280 Why?
Laccase2200370.280 Why?
Genetic Enhancement12006180.280 Why?
High-Throughput Screening Assays220139440.280 Why?
Phenylacetates120061140.280 Why?
Escherichia coli Proteins2201110520.280 Why?
Ethane1200540.280 Why?
Base Sequence142010127970.270 Why?
Metabolic Networks and Pathways120107820.270 Why?
Cellulose320101230.270 Why?
Gene Expression Regulation, Bacterial5200711190.270 Why?
Buspirone12006820.270 Why?
4-Butyrolactone42007630.270 Why?
Amidohydrolases220001690.260 Why?
Repressor Proteins6201030200.260 Why?
Hydrogen-Ion Concentration8200925520.260 Why?
Molecular Sequence Data152010181120.260 Why?
Pichia22006510.250 Why?
Pharmaceutical Preparations3200910710.250 Why?
Databases, Protein320123830.250 Why?
Chromatography, High Pressure Liquid4200015740.240 Why?
Saccharomyces cerevisiae Proteins5201018840.240 Why?
Bacillus22004770.240 Why?
Propranolol120065020.240 Why?
Structural Homology, Protein12004910.240 Why?
Norleucine1200360.240 Why?
Sordariales1200310.230 Why?
Adaptation, Physiological2200013100.230 Why?
Peroxidases120031380.220 Why?
Nucleic Acid Heteroduplexes22000470.220 Why?
Molecular Structure7200819070.220 Why?
Glucose Oxidase12002190.220 Why?
Hydrogen Peroxide320047300.220 Why?
Methylphenazonium Methosulfate1200230.220 Why?
Nitroblue Tetrazolium12002170.220 Why?
Structure-Activity Relationship7200731330.210 Why?
Trans-Activators3200729240.210 Why?
Picolines12001140.200 Why?
Computational Biology6200935180.200 Why?
Cell Communication2200616190.200 Why?
Imino Acids31997190.200 Why?
Models, Theoretical5200835840.200 Why?
Polymers3200216180.200 Why?
Cytochrome P-450 CYP1A212001680.200 Why?
Oxygen5200741690.200 Why?
Hypocrea2201120.190 Why?
Sequence Homology, Amino Acid4201228370.190 Why?
Sequence Homology, Nucleic Acid1200210860.190 Why?
Esterases12000950.190 Why?
Staphylococcus aureus3200314490.190 Why?
Glucose2201043910.180 Why?
Pseudomonas aeruginosa1200712100.180 Why?
Gene Expression5200577900.180 Why?
Biocatalysis220101670.180 Why?
Biosensing Techniques320136680.170 Why?
Bacteria2200721020.170 Why?
Templates, Genetic420022110.170 Why?
Sequence Alignment5201022570.170 Why?
Protein Denaturation420042370.170 Why?
Tryptophan220034780.170 Why?
Algorithms92012138530.170 Why?
Ethanol1200513370.170 Why?
Protein Binding9201393870.160 Why?
Alcohols32003920.160 Why?
Microbial Sensitivity Tests2200218710.160 Why?
Multigene Family1200211020.160 Why?
Flagellin119991250.160 Why?
Ligands7201132930.160 Why?
Luminescent Measurements120004050.160 Why?
DNA Mutational Analysis2200341870.150 Why?
Cold Temperature120007740.150 Why?
Crystallography, X-Ray3201220140.140 Why?
Circular Dichroism320023540.140 Why?
Serine Endopeptidases2199910730.140 Why?
Isoenzymes1200117250.140 Why?
Peptide Synthases11996800.140 Why?
Gene Expression Regulation22007120710.140 Why?
Metalloendopeptidases119983960.140 Why?
Half-Life320016580.140 Why?
Galactose220103060.130 Why?
Bioreactors220082360.130 Why?
Organic Chemicals220082110.130 Why?
Solubility3200210830.130 Why?
Membranes, Artificial119973780.130 Why?
Pseudomonas putida22008460.130 Why?
Peptide Fragments1200750950.120 Why?
Silicon Dioxide119952130.120 Why?
Hydrolysis220096820.120 Why?
Biophysics220073830.120 Why?
Genetic Variation7200765400.120 Why?
Species Specificity3200924790.120 Why?
Lipid Bilayers119963810.120 Why?
Conserved Sequence2200712020.120 Why?
Thermotoga maritima12012130.110 Why?
Automation320015840.110 Why?
Trichoderma12012110.110 Why?
Green Fluorescent Proteins6200520880.110 Why?
Talaromyces1201270.110 Why?
Luminescent Proteins420008530.110 Why?
Manganese220114080.110 Why?
Bacteriological Techniques220052760.110 Why?
Amino Acid Motifs220079360.100 Why?
Normal Distribution120122800.100 Why?
Fluorescence320057510.100 Why?
Biodegradation, Environmental220022190.100 Why?
Congo Red12011470.100 Why?
Carboxymethylcellulose Sodium12011390.100 Why?
Sequence Analysis, Protein120122570.100 Why?
Electrochemistry420051450.100 Why?
Spectrophotometry220013130.100 Why?
Organisms, Genetically Modified12010640.100 Why?
Time Factors102011400540.100 Why?
Artificial Gene Fusion22001570.100 Why?
Phylogeny3201027970.100 Why?
Chlorobenzenes22001280.100 Why?
Hydro-Lyases12010940.090 Why?
Metalloproteins119911000.090 Why?
Models, Biological6200895810.090 Why?
Astemizole1200920.090 Why?
Candida220061720.090 Why?
DNA Repair1199920420.090 Why?
Chromones120091540.090 Why?
Alkaloids120101900.090 Why?
Chimera220034850.090 Why?
Imidazoles1199612050.090 Why?
Dosage Compensation, Genetic120102110.090 Why?
DNA-Directed DNA Polymerase220034840.090 Why?
Probability2200525020.090 Why?
Adaptation, Biological120101520.090 Why?
1-Butanol12008130.090 Why?
Proteomics1200236180.090 Why?
Nucleic Acid Hybridization2200213740.090 Why?
Carbohydrate Sequence120094140.090 Why?
Verapamil120092440.080 Why?
Contrast Media3201352950.080 Why?
Halogenation12008420.080 Why?
Surface Properties3199711820.080 Why?
Ascomycota12009820.080 Why?
Monosaccharide Transport Proteins120104400.080 Why?
Lipids2199733020.080 Why?
Sequence Analysis, DNA4200248010.080 Why?
Enzyme Activation4200437010.080 Why?
Image Processing, Computer-Assisted3200189250.080 Why?
Chromatography, Gas120081560.080 Why?
Animals1820121685610.080 Why?
Molecular Conformation220075630.080 Why?
Drug Stability319932900.080 Why?
Terpenes12008980.080 Why?
Growth Hormone119917030.080 Why?
Horses319943040.080 Why?
Fluorescent Dyes1199619150.080 Why?
Whales31994300.080 Why?
Deoxyribonuclease I220002280.080 Why?
Glycosylation2200311230.080 Why?
Magnetic Resonance Spectroscopy3201237600.080 Why?
Hydrolases120081390.080 Why?
Genetic Vectors3200434200.070 Why?
Mycobacterium120082490.070 Why?
Colony Count, Microbial220053310.070 Why?
Hydrogen Bonding220112930.070 Why?
Glycolysis120118250.070 Why?
Operon120073600.070 Why?
Biomedical Engineering120082950.070 Why?
Population Density120071940.070 Why?
Laurates1200690.070 Why?
DNA-Cytosine Methylases12006170.070 Why?
Morpholines120095610.070 Why?
Pantoea12006140.070 Why?
Microscopy, Fluorescence3199926990.070 Why?
Base Pairing120061430.070 Why?
Genes, Duplicate12005330.070 Why?
Drug Design3201010780.070 Why?
Polyethylene Glycols4199411810.070 Why?
Software4200444340.070 Why?
Steroids120109310.070 Why?
ISCOMs1200420.060 Why?
Culture Media220059020.060 Why?
Cyclopentanes12005930.060 Why?
Holoenzymes12004410.060 Why?
Pyrenes12004460.060 Why?
Carboxylic Acids12005990.060 Why?
Gene Duplication120063300.060 Why?
Indicators and Reagents219974620.060 Why?
Bayes Theorem1201223030.060 Why?
Escherichia1200460.060 Why?
Coculture Techniques1200813410.060 Why?
Styrene12004240.060 Why?
Coenzymes12004910.060 Why?
Static Electricity120052670.060 Why?
Vibrio12004390.060 Why?
Oligonucleotides119875720.060 Why?
Frameshift Mutation120063990.060 Why?
Helix-Turn-Helix Motifs12003130.060 Why?
Poisson Distribution120055120.060 Why?
Lipase120063150.060 Why?
Ecosystem120084710.060 Why?
Genetic Techniques120074350.060 Why?
Plants120053140.060 Why?
DNA Restriction Enzymes120035700.060 Why?
Recombinases12003670.060 Why?
Farnesyltranstransferase12003760.060 Why?
Geranylgeranyl-Diphosphate Geranylgeranyltransferase1200230.060 Why?
Environment2200411150.060 Why?
Peroxides12003740.060 Why?
Genes2200518920.060 Why?
DNA, Bacterial2201014650.060 Why?
Anthraquinones12002350.060 Why?
Crystallization220115250.060 Why?
Anthracenes12002840.060 Why?
Sulfonic Acids12003950.050 Why?
Chromatography, Thin Layer120022230.050 Why?
Phosphogluconate Dehydrogenase12002220.050 Why?
Hydrazones120031020.050 Why?
Blood Glucose1199762490.050 Why?
Myoglobin219941600.050 Why?
Toluene12002320.050 Why?
Indoles2200218340.050 Why?
Biological Evolution2199910740.050 Why?
Ampicillin120021380.050 Why?
Crossing Over, Genetic12002950.050 Why?
Benzothiazoles120032470.050 Why?
Restriction Mapping219938780.050 Why?
Gene Regulatory Networks1201017070.050 Why?
Transformation, Bacterial12001780.050 Why?
Chymotrypsin120011490.050 Why?
Isoleucine120011110.050 Why?
Vaccines, Synthetic120046330.050 Why?
Oligonucleotide Probes120024270.050 Why?
Protons2199711260.050 Why?
Research Design1199759790.050 Why?
Fusarium12001510.050 Why?
Calibration120048150.050 Why?
Transcription Factors32010121640.050 Why?
Chemical Phenomena220115170.050 Why?
Zinc Fingers120035850.050 Why?
Sequence Homology120012030.050 Why?
Intramolecular Lyases12000110.050 Why?
Computer Simulation4200861910.050 Why?
Trypsin120015090.050 Why?
Dithionitrobenzoic Acid12000210.050 Why?
Peroxidase120046100.050 Why?
Body Patterning120056260.050 Why?
Organometallic Compounds120046650.050 Why?
Pliability12000630.050 Why?
Gene Rearrangement1200611790.050 Why?
Phosphoribosylglycinamide Formyltransferase1199930.050 Why?
Hydroxymethyl and Formyl Transferases11999170.050 Why?
Camphor 5-Monooxygenase1199920.050 Why?
Transformation, Genetic120001920.050 Why?
Coloring Agents120025650.050 Why?
Pigments, Biological11999530.050 Why?
DNA-Binding Proteins2201096390.040 Why?
Magnetic Resonance Imaging32013353420.040 Why?
Catechols11999610.040 Why?
Cluster Analysis1200727130.040 Why?
Sheep2199414370.040 Why?
Quality Control120028410.040 Why?
Nitrophenols120001720.040 Why?
Repetitive Sequences, Nucleic Acid120027990.040 Why?
Sensitivity and Specificity22007147200.040 Why?
Electrophoresis, Polyacrylamide Gel1200218010.040 Why?
Introns120029910.040 Why?
Rats32012242650.040 Why?
Adjuvants, Immunologic1200410000.040 Why?
Linear Models1200959480.040 Why?
Antigens1200414620.040 Why?
Thermolysin11998140.040 Why?
Glucosides120024460.040 Why?
Polynucleotides11998350.040 Why?
Oligodeoxyribonucleotides120007080.040 Why?
Protein Subunits120029600.040 Why?
DNA Polymerase I11998370.040 Why?
Databases, Genetic1200517800.040 Why?
Vibration120003250.040 Why?
DNA Nucleotidyltransferases119981930.040 Why?
Genotype12012129460.040 Why?
Flow Cytometry2199959750.040 Why?
Polymorphism, Restriction Fragment Length119997680.040 Why?
Carrier Proteins1199150190.040 Why?
Calorimetry, Differential Scanning11997940.040 Why?
Water2199613880.040 Why?
T-Lymphocytes, Cytotoxic1200418200.040 Why?
Calcium2200057530.040 Why?
Blotting, Northern1199915810.040 Why?
Humans1420107420880.040 Why?
Biological Products120068560.040 Why?
Oligonucleotide Array Sequence Analysis1200539200.040 Why?
Polymorphism, Genetic1200743280.040 Why?
Cattle2199439230.040 Why?
Nanotechnology120027090.030 Why?
Cell Division1200445640.030 Why?
Streptavidin11996810.030 Why?
Cells, Cultured12012192230.030 Why?
Spectrophotometry, Ultraviolet119962200.030 Why?
Ultraviolet Rays1200110590.030 Why?
Heterocyclic Compounds119972490.030 Why?
Hemoglobins2199415320.030 Why?
Isocitrate Dehydrogenase120018700.030 Why?
Feedback, Physiological220104790.030 Why?
Phosphatidylcholines119974110.030 Why?
Bacterial Outer Membrane Proteins119984040.030 Why?
Ions119962640.030 Why?
Signal Transduction32010233870.030 Why?
Data Interpretation, Statistical1200527140.030 Why?
Chromatography, Ion Exchange119953050.030 Why?
Phenotype12012163310.030 Why?
Adsorption119952010.030 Why?
Light1200113740.030 Why?
Phosvitin1199410.030 Why?
Tuna11994190.030 Why?
Blood Glucose Self-Monitoring119974360.030 Why?
Pressure1199712030.030 Why?
Magnesium119978130.030 Why?
Titrimetry12013360.030 Why?
Gene Expression Regulation, Enzymologic1199812130.030 Why?
Microscopy, Electron, Scanning119959620.030 Why?
Models, Structural119933610.030 Why?
Ribonuclease, Pancreatic119941540.030 Why?
Tubocurarine11992630.030 Why?
Anilides119964040.030 Why?
Models, Statistical2200451000.030 Why?
Peptides2199643920.030 Why?
Ovalbumin119947190.030 Why?
Phenytoin119921970.030 Why?
Promoter Regions, Genetic2200558670.030 Why?
Resins, Plant11991200.030 Why?
Neuromuscular Blocking Agents119921300.030 Why?
Cell Separation1199717490.020 Why?
Chemistry, Physical119911560.020 Why?
Microfluidics220086620.020 Why?
Zinc119956830.020 Why?
Logistic Models12006134030.020 Why?
Chorismate Mutase1201070.020 Why?
Serum Albumin119946740.020 Why?
Protoporphyrins120111640.020 Why?
Dose-Response Relationship, Drug22001109430.020 Why?
Forecasting1199929480.020 Why?
Egtazic Acid119891730.020 Why?
Consensus Sequence120103770.020 Why?
Disulfides120114570.020 Why?
Genes, Regulator120103780.020 Why?
Genes, Fungal120104550.020 Why?
Neurotransmitter Agents120136470.020 Why?
Dextrans119915920.020 Why?
Molecular Weight1199122550.020 Why?
Population Growth12008510.020 Why?
Oscillometry120081470.020 Why?
Gene Expression Regulation, Fungal120105020.020 Why?
Dimethylpolysiloxanes120081490.020 Why?
Swine1199759340.020 Why?
Brain Chemistry120109810.020 Why?
Population Dynamics120083010.020 Why?
Isopropyl Thiogalactoside12005120.020 Why?
Plant Proteins119883640.020 Why?
Buffers120041470.020 Why?
Papillomavirus E7 Proteins120041230.020 Why?
Cytotoxicity Tests, Immunologic120043290.020 Why?
Epistasis, Genetic120073650.020 Why?
Systems Biology120084690.020 Why?
Mathematics120057270.010 Why?
Microscopy, Atomic Force120042480.010 Why?
Solutions120044260.010 Why?
Dimethyl Sulfoxide120042490.010 Why?
Open Reading Frames120068100.010 Why?
Furans120041940.010 Why?
Oncogene Proteins, Viral120043620.010 Why?
Spectrum Analysis120044510.010 Why?
Diabetes Mellitus, Type 11199733360.010 Why?
Bacteriophage T412001350.010 Why?
Muramidase120011740.010 Why?
Myocardium1199447750.010 Why?
Statistics, Nonparametric1200628850.010 Why?
Cytochrome P-450 CYP2E111999360.010 Why?
Silicones119992480.010 Why?
Transcriptional Activation1200517820.010 Why?
Immunity, Cellular1200416060.010 Why?
Anti-Bacterial Agents1199671530.010 Why?
Immunologic Memory1200413480.010 Why?
Analysis of Variance1200663650.010 Why?
Iron1200517730.010 Why?
Regression Analysis1200664520.010 Why?
Drosophila melanogaster1200517040.010 Why?
Cell Line, Tumor12010166650.010 Why?
Orosomucoid11992450.010 Why?
Vaccination1200432560.010 Why?
Receptors, Cholinergic119922380.010 Why?
Rats, Inbred Strains1199221910.010 Why?
Transcription, Genetic1200577210.010 Why?
Cell Differentiation12005114700.000 Why?
Drug Interactions1199214580.000 Why?
Blood Proteins1199211220.000 Why?
Mice, Inbred C57BL12004218210.000 Why?
Brain12010263430.000 Why?
Mice12004810450.000 Why?
Male119923495380.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.