Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Frances Lowe Arnold, Ph.D.

Concepts (512)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Directed Molecular Evolution5120131617.950 Why?
Protein Engineering5720135487.370 Why?
Cytochrome P-450 Enzyme System4220134127.270 Why?
Recombination, Genetic37201215194.240 Why?
Enzymes1920132572.960 Why?
Evolution, Molecular23201218802.350 Why?
Mixed Function Oxygenases1520102652.280 Why?
Escherichia coli46201342092.130 Why?
Proteins34201260302.090 Why?
Bacillus megaterium122012191.740 Why?
Mutagenesis32201212301.610 Why?
Subtilisins142001811.560 Why?
Recombinant Fusion Proteins19201237301.510 Why?
Enzyme Stability2920102191.470 Why?
Bacterial Proteins27201338421.410 Why?
Models, Molecular49201254331.360 Why?
Gene Library14201310551.220 Why?
Cellulases32012101.190 Why?
Catalysis2620127731.150 Why?
Mutagenesis, Site-Directed22201216921.140 Why?
Cellulose 1,4-beta-Cellobiosidase3201261.130 Why?
Carotenoids620066211.060 Why?
Oxygenases52002590.950 Why?
NADPH-Ferrihemoprotein Reductase142013300.900 Why?
Recombinant Proteins25201265200.870 Why?
Cellulase32011100.860 Why?
Propane42010120.860 Why?
Protein Folding1220128700.840 Why?
Protein Conformation29201239650.830 Why?
Substrate Specificity20201017900.820 Why?
Temperature21201222230.820 Why?
Butanols22012190.800 Why?
Hydroxylation1320121370.800 Why?
Biotechnology920012810.790 Why?
Fungal Proteins520129070.790 Why?
beta-Lactamases820123040.770 Why?
Genetic Engineering920119310.750 Why?
Carboxylic Ester Hydrolases72003980.720 Why?
Polymerase Chain Reaction22201360740.700 Why?
Metals1019977190.680 Why?
Alkanes32012410.680 Why?
NADP620122270.670 Why?
Models, Chemical720126110.660 Why?
Alkenes22012540.650 Why?
Protein Stability620135780.650 Why?
Fungi320113380.650 Why?
Bacillus subtilis820003510.620 Why?
Horseradish Peroxidase520011660.610 Why?
Colorimetry320041500.610 Why?
Oxidoreductases720064120.580 Why?
Peptide Library820103470.570 Why?
Thermodynamics1220105930.570 Why?
Clostridium220121000.560 Why?
Histidine1019973080.560 Why?
Saccharomyces cerevisiae11201026740.560 Why?
Subtilisin32001120.550 Why?
Kinetics21200963700.540 Why?
Cytochrome c Group819961220.540 Why?
Plasmids14200822650.530 Why?
Oxidation-Reduction15201222310.530 Why?
Chelating Agents1020043870.520 Why?
Mutation292012300160.500 Why?
Farnesyl-Diphosphate Farnesyltransferase3200450.500 Why?
Glycoside Hydrolases220121350.490 Why?
Catalytic Domain820127040.490 Why?
Biofilms320116260.490 Why?
Amino Acids5201017170.460 Why?
Heme820133130.440 Why?
Aldehydes220121700.430 Why?
DNA, Recombinant720034550.430 Why?
Monosaccharides22010660.420 Why?
Methane12012520.420 Why?
Alkyl and Aryl Transferases22003860.420 Why?
Lactococcus lactis12012290.410 Why?
Galactose Oxidase22002120.410 Why?
Binding Sites18200960510.400 Why?
Biofuels22011420.400 Why?
Drug Evaluation, Preclinical3200213330.400 Why?
Solvents820042940.400 Why?
Stereoisomerism720126130.390 Why?
Alcohol Oxidoreductases120121680.390 Why?
Combinatorial Chemistry Techniques220101350.390 Why?
Amino Acid Substitution8200817390.390 Why?
Ketol-Acid Reductoisomerase1201110.390 Why?
Copper919973670.390 Why?
Amino Acid Sequence192012134410.380 Why?
Chromatography, Affinity619965320.380 Why?
Clostridium thermocellum1201020.380 Why?
Clostridium cellulolyticum1201020.380 Why?
Cyclopropanes120124320.370 Why?
Actinomycetales12010330.370 Why?
Carbon320106650.370 Why?
Point Mutation8200215950.360 Why?
Hydrogen220101720.360 Why?
Alcohol Dehydrogenase120111110.360 Why?
Selection, Genetic620108680.350 Why?
Hot Temperature10201014370.350 Why?
Protein Structure, Tertiary12201137920.340 Why?
Cloning, Molecular11200741720.330 Why?
Protein Biosynthesis3200521000.330 Why?
DNA12200371960.330 Why?
Methionine220035720.330 Why?
Butanes1200860.330 Why?
Erwinia32004210.330 Why?
Protein Structure, Secondary7200812290.320 Why?
Oxidoreductases, N-Demethylating120091090.320 Why?
DNA Primers7200628170.320 Why?
Dimethylformamide51996200.320 Why?
Industrial Microbiology1200870.320 Why?
Dopamine3201316060.310 Why?
Biotransformation420101660.310 Why?
Symbiosis120112940.310 Why?
Alanine120106090.300 Why?
Models, Genetic8201034310.300 Why?
Genes, Bacterial6200610730.290 Why?
Cytochromes c319941730.290 Why?
Serotonin1201210410.290 Why?
Genetic Enhancement12006170.270 Why?
High-Throughput Screening Assays220139330.270 Why?
Laccase2200380.270 Why?
Base Sequence142010124210.270 Why?
Quorum Sensing120071370.270 Why?
Phenylacetates120061120.270 Why?
Ethane1200530.260 Why?
Escherichia coli Proteins2201110640.260 Why?
Metabolic Networks and Pathways120107890.260 Why?
Cellulose320101170.260 Why?
Gene Expression Regulation, Bacterial5200711310.260 Why?
Buspirone12006810.260 Why?
Repressor Proteins6201029850.260 Why?
4-Butyrolactone42007610.250 Why?
Hydrogen-Ion Concentration8200924950.250 Why?
Molecular Sequence Data152010176290.250 Why?
Amidohydrolases220001580.250 Why?
Pichia22006490.240 Why?
Pharmaceutical Preparations3200910860.240 Why?
Databases, Protein320123870.240 Why?
Saccharomyces cerevisiae Proteins5201018360.240 Why?
Chromatography, High Pressure Liquid4200015400.230 Why?
Propranolol120064900.230 Why?
Bacillus22004780.230 Why?
Structural Homology, Protein12004870.230 Why?
Norleucine1200360.230 Why?
Adaptation, Physiological2200013000.220 Why?
Sordariales1200310.220 Why?
Peroxidases120031340.210 Why?
Nucleic Acid Heteroduplexes22000460.210 Why?
Molecular Structure7200818780.210 Why?
Glucose Oxidase12002180.210 Why?
Hydrogen Peroxide320047300.210 Why?
Methylphenazonium Methosulfate1200230.210 Why?
Nitroblue Tetrazolium12002160.210 Why?
Structure-Activity Relationship7200730740.200 Why?
Trans-Activators3200728520.200 Why?
Computational Biology6200935090.200 Why?
Cell Communication2200616540.200 Why?
Picolines12001100.200 Why?
Models, Theoretical5200835670.190 Why?
Imino Acids31997190.190 Why?
Polymers3200216140.190 Why?
Oxygen5200742260.190 Why?
Cytochrome P-450 CYP1A212001690.190 Why?
Hypocrea2201120.190 Why?
Sequence Homology, Amino Acid4201227470.180 Why?
Sequence Homology, Nucleic Acid1200210580.180 Why?
Glucose2201043450.180 Why?
Staphylococcus aureus3200314570.180 Why?
Esterases12000980.170 Why?
Gene Expression5200575680.170 Why?
Biocatalysis220101700.170 Why?
Biosensing Techniques320136470.170 Why?
Pseudomonas aeruginosa1200712720.170 Why?
Sequence Alignment5201021780.170 Why?
Templates, Genetic420021890.170 Why?
Bacteria2200721920.160 Why?
Ethanol1200513200.160 Why?
Protein Denaturation420042420.160 Why?
Tryptophan220034820.160 Why?
Algorithms92012140180.160 Why?
Protein Binding9201393450.160 Why?
Multigene Family1200210760.160 Why?
Alcohols32003940.160 Why?
Luminescent Measurements120003400.150 Why?
Ligands7201132680.150 Why?
Flagellin119991240.150 Why?
Microbial Sensitivity Tests2200219360.150 Why?
DNA Mutational Analysis2200341100.140 Why?
Crystallography, X-Ray3201219890.140 Why?
Circular Dichroism320023440.140 Why?
Serine Endopeptidases2199910220.140 Why?
Gene Expression Regulation22007118740.140 Why?
Cold Temperature120007840.140 Why?
Isoenzymes1200116870.140 Why?
Peptide Synthases11996800.130 Why?
Metalloendopeptidases119983930.130 Why?
Half-Life320016500.130 Why?
Galactose220102940.130 Why?
Organic Chemicals220082100.130 Why?
Bioreactors220082460.130 Why?
Membranes, Artificial119973660.120 Why?
Solubility3200210890.120 Why?
Peptide Fragments1200751100.120 Why?
Pseudomonas putida22008490.120 Why?
Hydrolysis220096610.120 Why?
Silicon Dioxide119952160.120 Why?
Biophysics220073790.120 Why?
Genetic Variation7200765610.110 Why?
Species Specificity3200924110.110 Why?
Conserved Sequence2200711620.110 Why?
Lipid Bilayers119963830.110 Why?
Automation320015850.110 Why?
Trichoderma1201290.110 Why?
Thermotoga maritima12012120.110 Why?
Green Fluorescent Proteins6200520630.110 Why?
Talaromyces12012100.110 Why?
Luminescent Proteins420008360.100 Why?
Manganese220113930.100 Why?
Bacteriological Techniques220052750.100 Why?
Amino Acid Motifs220079270.100 Why?
Normal Distribution120122720.100 Why?
Fluorescence320057560.100 Why?
Biodegradation, Environmental220022160.100 Why?
Carboxymethylcellulose Sodium12011380.100 Why?
Sequence Analysis, Protein120122610.100 Why?
Congo Red12011480.100 Why?
Spectrophotometry220013090.090 Why?
Electrochemistry420051450.090 Why?
Time Factors102011399130.090 Why?
Organisms, Genetically Modified12010630.090 Why?
Artificial Gene Fusion22001560.090 Why?
Chlorobenzenes22001280.090 Why?
Models, Biological6200894610.090 Why?
Hydro-Lyases12010940.090 Why?
Metalloproteins119911010.090 Why?
Phylogeny3201028060.090 Why?
Astemizole1200920.090 Why?
Candida220061710.090 Why?
DNA Repair1199920430.090 Why?
Imidazoles1199611750.080 Why?
Chimera220034530.080 Why?
Chromones120091480.080 Why?
Alkaloids120101920.080 Why?
Probability2200524750.080 Why?
Dosage Compensation, Genetic120102070.080 Why?
Adaptation, Biological120101470.080 Why?
DNA-Directed DNA Polymerase220034840.080 Why?
Nucleic Acid Hybridization2200213010.080 Why?
1-Butanol12008130.080 Why?
Carbohydrate Sequence120094110.080 Why?
Verapamil120092420.080 Why?
Contrast Media3201353050.080 Why?
Sequence Analysis, DNA4200247390.080 Why?
Surface Properties3199711610.080 Why?
Lipids2199733320.080 Why?
Halogenation12008480.080 Why?
Enzyme Activation4200435910.080 Why?
Ascomycota12009810.080 Why?
Monosaccharide Transport Proteins120104360.080 Why?
Proteomics1200238360.080 Why?
Image Processing, Computer-Assisted3200189980.080 Why?
Growth Hormone119915690.080 Why?
Chromatography, Gas120081510.080 Why?
Animals1820121682010.080 Why?
Molecular Conformation220075440.080 Why?
Terpenes12008960.080 Why?
Drug Stability319932910.080 Why?
Horses319943000.080 Why?
Fluorescent Dyes1199619010.070 Why?
Glycosylation2200310980.070 Why?
Whales31994300.070 Why?
Magnetic Resonance Spectroscopy3201237690.070 Why?
Deoxyribonuclease I220002240.070 Why?
Hydrolases120081470.070 Why?
Genetic Vectors3200433920.070 Why?
Mycobacterium120082510.070 Why?
Colony Count, Microbial220053280.070 Why?
Hydrogen Bonding220112910.070 Why?
Biomedical Engineering120082860.070 Why?
Glycolysis120118350.070 Why?
Operon120073720.070 Why?
Population Density120071930.070 Why?
Laurates1200670.070 Why?
DNA-Cytosine Methylases12006170.070 Why?
Morpholines120095810.070 Why?
Pantoea12006140.070 Why?
Microscopy, Fluorescence3199926390.070 Why?
Drug Design3201010450.070 Why?
Base Pairing120061400.060 Why?
Genes, Duplicate12005300.060 Why?
Software4200444310.060 Why?
Polyethylene Glycols4199411820.060 Why?
Steroids120109290.060 Why?
ISCOMs1200420.060 Why?
Cyclopentanes12005870.060 Why?
Culture Media220058950.060 Why?
Holoenzymes12004390.060 Why?
Carboxylic Acids12005900.060 Why?
Gene Duplication120063140.060 Why?
Pyrenes12004490.060 Why?
Indicators and Reagents219974600.060 Why?
Bayes Theorem1201223260.060 Why?
Escherichia1200470.060 Why?
Coculture Techniques1200813360.060 Why?
Styrene12004240.060 Why?
Static Electricity120052610.060 Why?
Coenzymes120041020.060 Why?
Oligonucleotides119875660.060 Why?
Frameshift Mutation120063920.060 Why?
Poisson Distribution120055040.060 Why?
Vibrio12004400.060 Why?
Genetic Techniques120074280.060 Why?
Helix-Turn-Helix Motifs12003140.060 Why?
Ecosystem120084870.060 Why?
Lipase120063240.060 Why?
Environment2200411230.050 Why?
Plants120053270.050 Why?
Farnesyltranstransferase12003710.050 Why?
DNA Restriction Enzymes120035500.050 Why?
Genes2200518230.050 Why?
Recombinases12003670.050 Why?
Geranylgeranyl-Diphosphate Geranylgeranyltransferase1200230.050 Why?
Peroxides12003740.050 Why?
DNA, Bacterial2201014710.050 Why?
Crystallization220115330.050 Why?
Anthraquinones12002410.050 Why?
Anthracenes12002830.050 Why?
Chromatography, Thin Layer120022130.050 Why?
Sulfonic Acids120031030.050 Why?
Indoles2200218300.050 Why?
Phosphogluconate Dehydrogenase12002220.050 Why?
Hydrazones120031030.050 Why?
Biological Evolution2199910700.050 Why?
Blood Glucose1199763900.050 Why?
Myoglobin219941590.050 Why?
Toluene12002320.050 Why?
Ampicillin120021360.050 Why?
Crossing Over, Genetic12002920.050 Why?
Restriction Mapping219938510.050 Why?
Benzothiazoles120032470.050 Why?
Vaccines, Synthetic120046120.050 Why?
Gene Regulatory Networks1201017450.050 Why?
Transformation, Bacterial12001760.050 Why?
Chymotrypsin120011380.050 Why?
Isoleucine120011100.050 Why?
Oligonucleotide Probes120024160.050 Why?
Protons2199711120.050 Why?
Research Design1199761740.050 Why?
Transcription Factors32010121160.050 Why?
Fusarium12001510.050 Why?
Calibration120048170.050 Why?
Chemical Phenomena220115060.050 Why?
Zinc Fingers120035780.050 Why?
Sequence Homology120011960.050 Why?
Intramolecular Lyases12000110.050 Why?
Organometallic Compounds120046460.050 Why?
Computer Simulation4200862330.050 Why?
Gene Rearrangement1200611250.050 Why?
Trypsin120014950.050 Why?
Peroxidase120046100.040 Why?
Dithionitrobenzoic Acid12000200.040 Why?
Body Patterning120056320.040 Why?
Pliability12000590.040 Why?
Phosphoribosylglycinamide Formyltransferase1199930.040 Why?
Hydroxymethyl and Formyl Transferases11999180.040 Why?
Coloring Agents120025620.040 Why?
Transformation, Genetic120001920.040 Why?
Camphor 5-Monooxygenase1199920.040 Why?
Pigments, Biological11999520.040 Why?
DNA-Binding Proteins2201095860.040 Why?
Cluster Analysis1200727000.040 Why?
Sheep2199414360.040 Why?
Catechols11999620.040 Why?
Nitrophenols120001690.040 Why?
Repetitive Sequences, Nucleic Acid120027830.040 Why?
Quality Control120028310.040 Why?
Electrophoresis, Polyacrylamide Gel1200217380.040 Why?
Magnetic Resonance Imaging32013364020.040 Why?
Introns120029680.040 Why?
Sensitivity and Specificity22007146480.040 Why?
Rats32012237170.040 Why?
Linear Models1200958660.040 Why?
Adjuvants, Immunologic120049900.040 Why?
Antigens1200414410.040 Why?
Thermolysin11998140.040 Why?
Databases, Genetic1200517420.040 Why?
Polynucleotides11998270.040 Why?
Protein Subunits120029420.040 Why?
Oligodeoxyribonucleotides120007040.040 Why?
DNA Polymerase I11998430.040 Why?
Vibration120003280.040 Why?
Carrier Proteins1199149350.040 Why?
Flow Cytometry2199958630.040 Why?
DNA Nucleotidyltransferases119981750.040 Why?
Genotype12012129780.040 Why?
Polymorphism, Restriction Fragment Length119997670.040 Why?
Glucosides120025120.040 Why?
Calorimetry, Differential Scanning119971000.040 Why?
T-Lymphocytes, Cytotoxic1200417790.040 Why?
Water2199614090.040 Why?
Calcium2200057170.040 Why?
Blotting, Northern1199915450.030 Why?
Oligonucleotide Array Sequence Analysis1200537770.030 Why?
Polymorphism, Genetic1200742420.030 Why?
Humans1420107606170.030 Why?
Cattle2199438410.030 Why?
Biological Products120069120.030 Why?
Nanotechnology120027130.030 Why?
Cell Division1200444570.030 Why?
Cells, Cultured12012189370.030 Why?
Streptavidin11996810.030 Why?
Spectrophotometry, Ultraviolet119962010.030 Why?
Ultraviolet Rays1200110790.030 Why?
Heterocyclic Compounds119972450.030 Why?
Hemoglobins2199415240.030 Why?
Feedback, Physiological220104750.030 Why?
Phosphatidylcholines119974050.030 Why?
Bacterial Outer Membrane Proteins119984040.030 Why?
Ions119962560.030 Why?
Data Interpretation, Statistical1200526890.030 Why?
Signal Transduction32010234160.030 Why?
Chromatography, Ion Exchange119952970.030 Why?
Light1200113520.030 Why?
Adsorption119951970.030 Why?
Isocitrate Dehydrogenase120019370.030 Why?
Phenotype12012165710.030 Why?
Phosvitin1199410.030 Why?
Tuna11994180.030 Why?
Pressure1199711500.030 Why?
Blood Glucose Self-Monitoring119974670.030 Why?
Gene Expression Regulation, Enzymologic1199811690.030 Why?
Magnesium119978040.030 Why?
Microscopy, Electron, Scanning119959440.030 Why?
Titrimetry12013350.030 Why?
Models, Structural119933400.030 Why?
Ribonuclease, Pancreatic119941490.030 Why?
Models, Statistical2200450730.030 Why?
Tubocurarine11992620.030 Why?
Anilides119964110.030 Why?
Peptides2199643540.030 Why?
Ovalbumin119946750.020 Why?
Promoter Regions, Genetic2200557800.020 Why?
Phenytoin119921900.020 Why?
Cell Separation1199717180.020 Why?
Resins, Plant11991200.020 Why?
Neuromuscular Blocking Agents119921290.020 Why?
Microfluidics220086510.020 Why?
Logistic Models12006132450.020 Why?
Chemistry, Physical119911540.020 Why?
Zinc119956870.020 Why?
Chorismate Mutase1201060.020 Why?
Dose-Response Relationship, Drug22001107540.020 Why?
Protoporphyrins120111680.020 Why?
Serum Albumin119946720.020 Why?
Forecasting1199929240.020 Why?
Egtazic Acid119891670.020 Why?
Consensus Sequence120103640.020 Why?
Genes, Regulator120103730.020 Why?
Disulfides120114640.020 Why?
Genes, Fungal120104390.020 Why?
Dextrans119915730.020 Why?
Molecular Weight1199121850.020 Why?
Neurotransmitter Agents120136650.020 Why?
Population Growth12008500.020 Why?
Gene Expression Regulation, Fungal120104930.020 Why?
Oscillometry120081500.020 Why?
Dimethylpolysiloxanes120081420.020 Why?
Swine1199759070.020 Why?
Brain Chemistry120109600.020 Why?
Population Dynamics120083060.020 Why?
Isopropyl Thiogalactoside12005110.020 Why?
Plant Proteins119883690.020 Why?
Buffers120041460.010 Why?
Epistasis, Genetic120073500.010 Why?
Papillomavirus E7 Proteins120041090.010 Why?
Cytotoxicity Tests, Immunologic120043170.010 Why?
Systems Biology120084810.010 Why?
Mathematics120057070.010 Why?
Microscopy, Atomic Force120042530.010 Why?
Solutions120044120.010 Why?
Dimethyl Sulfoxide120042510.010 Why?
Oncogene Proteins, Viral120043400.010 Why?
Open Reading Frames120068130.010 Why?
Furans120042020.010 Why?
Spectrum Analysis120044520.010 Why?
Diabetes Mellitus, Type 11199734150.010 Why?
Bacteriophage T412001330.010 Why?
Myocardium1199447240.010 Why?
Muramidase120011670.010 Why?
Statistics, Nonparametric1200628490.010 Why?
Cytochrome P-450 CYP2E111999350.010 Why?
Silicones119992280.010 Why?
Transcriptional Activation1200517550.010 Why?
Immunity, Cellular1200415500.010 Why?
Immunologic Memory1200413550.010 Why?
Analysis of Variance1200662240.010 Why?
Anti-Bacterial Agents1199674020.010 Why?
Iron1200517900.010 Why?
Regression Analysis1200663380.010 Why?
Drosophila melanogaster1200517120.010 Why?
Cell Line, Tumor12010169670.010 Why?
Orosomucoid11992450.010 Why?
Vaccination1200433700.010 Why?
Receptors, Cholinergic119922440.010 Why?
Rats, Inbred Strains1199220880.010 Why?
Transcription, Genetic1200575830.010 Why?
Drug Interactions1199214150.000 Why?
Cell Differentiation12005115140.000 Why?
Blood Proteins1199211720.000 Why?
Mice, Inbred C57BL12004221150.000 Why?
Brain12010271010.000 Why?
Mice12004813680.000 Why?
Male119923603580.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.