Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Klaus J. van Leyen, Ph.D.

Concepts (385)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Arachidonate 15-Lipoxygenase232021846.990 Why?
Arachidonate 12-Lipoxygenase182021825.670 Why?
Lipoxygenase Inhibitors132021932.870 Why?
Stroke20202497211.380 Why?
Brain Ischemia10201930321.300 Why?
Infarction, Middle Cerebral Artery520244851.120 Why?
Lipoxygenase32017720.920 Why?
Tissue Plasminogen Activator6202111620.900 Why?
Oxidative Stress10201931140.800 Why?
Naphthalenes220211980.770 Why?
Fibrinolytic Agents3201920750.750 Why?
Isoxazoles220212330.730 Why?
Neurons16201694280.710 Why?
Brain Injuries6201920540.690 Why?
Flavanones32010740.660 Why?
Oligodendroglia320155370.640 Why?
Thrombolytic Therapy3201920550.520 Why?
Lipoxygenases12014130.490 Why?
Cerebral Hemorrhage7201926420.480 Why?
Apoptosis Inducing Factor22016510.480 Why?
Semaphorin-3A22012390.470 Why?
STAT Transcription Factors120151880.470 Why?
Endoplasmic Reticulum11201011250.460 Why?
Warfarin4201714820.450 Why?
Intracranial Hemorrhages120198090.450 Why?
Neuroprotective Agents520209560.430 Why?
Organelles320012640.430 Why?
Echoencephalography220111340.410 Why?
Enzyme Inhibitors7201737020.390 Why?
Leukomalacia, Periventricular120131840.390 Why?
Fatty Acids, Unsaturated120145400.380 Why?
Subarachnoid Hemorrhage1201910330.370 Why?
Ultrasonography, Doppler, Color120112320.350 Why?
Brain Edema420106040.350 Why?
Ischemic Attack, Transient220238740.350 Why?
Mice382024813260.350 Why?
Ultrasonography, Doppler, Transcranial120112810.340 Why?
Brain112019270920.340 Why?
Animals6020241680790.330 Why?
Glutamic Acid4201711730.320 Why?
Reticulocytes320142880.320 Why?
Microglia3202113580.320 Why?
Blood-Brain Barrier5201910270.310 Why?
Apoptosis6201794770.300 Why?
Cell Communication1201516510.300 Why?
Brain Infarction220212890.300 Why?
Aspirin1201931290.290 Why?
Platelet Aggregation Inhibitors1201927460.290 Why?
Hemorrhage2201934220.280 Why?
Anticoagulants4201947950.270 Why?
Macrophages2201957530.270 Why?
Mice, Inbred C57BL152024221270.270 Why?
Mice, Knockout92019143920.260 Why?
Disease Models, Animal112024182200.240 Why?
Cell Nucleus2201028810.230 Why?
Reperfusion320212710.220 Why?
Mitochondria5201736200.220 Why?
Glycopeptides219942200.210 Why?
Drug Evaluation, Preclinical1200813310.210 Why?
Brain Diseases1201115450.200 Why?
Intracellular Membranes320053870.200 Why?
Neural Stem Cells220228860.200 Why?
Antioxidants2200816670.200 Why?
Intracranial Embolism220211890.200 Why?
Molecular Chaperones320157540.190 Why?
Lipofuscin12020400.180 Why?
Cold-Shock Response12019160.170 Why?
Hypoxia, Brain220211390.160 Why?
Cells, Cultured92022189260.150 Why?
Proteasome Endopeptidase Complex1200513180.150 Why?
Glycogen Synthase Kinase 3320154120.150 Why?
Astrocytes4202213400.150 Why?
Platelet Function Tests120192710.150 Why?
Hippocampus4201637540.150 Why?
Cell Line72019155450.140 Why?
Annexin A212017430.140 Why?
Endothelial Cells5202235510.140 Why?
Coronary Thrombosis120194400.140 Why?
Glucose6202143420.130 Why?
Recovery of Function2201629810.130 Why?
Drug Therapy, Combination3202163040.120 Why?
Cerebral Cortex4201657750.120 Why?
Rats122021237040.120 Why?
Male2920243606930.110 Why?
Adrenal Cortex220051340.110 Why?
beta-Alanine12014820.110 Why?
Lipocalins120141610.110 Why?
Adipose Tissue, Brown120197660.110 Why?
Review Literature as Topic120153480.110 Why?
Cytoplasm2201014980.110 Why?
Brain Neoplasms3201190250.110 Why?
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid12012150.110 Why?
Secondary Prevention1201914720.110 Why?
Acute-Phase Proteins120142500.110 Why?
Golgi Apparatus119944030.100 Why?
Spermatozoa320106300.100 Why?
Immunohistochemistry52013110670.100 Why?
Vesicular Transport Proteins120153740.100 Why?
Capillary Permeability220177730.100 Why?
Corpus Striatum2201612340.100 Why?
Oligopeptides2201411790.100 Why?
In Situ Nick-End Labeling120136130.100 Why?
Cerebrospinal Fluid Pressure11991380.100 Why?
Second Messenger Systems120122010.100 Why?
Toll-Like Receptor 4120155770.100 Why?
Liver Diseases1202013010.100 Why?
Arachidonic Acid120134270.090 Why?
Globins120124050.090 Why?
Leukotrienes120122300.090 Why?
Reperfusion Injury2201510260.090 Why?
Hydrogen Sulfide120121410.090 Why?
Calcium2201757190.090 Why?
Blood Coagulation Factors220143660.090 Why?
Glutathione220125810.090 Why?
Signal Transduction82015234160.090 Why?
Gene Knockdown Techniques1201516020.090 Why?
Head Injuries, Closed119911330.090 Why?
Epididymis220102270.090 Why?
Humans3520207612080.090 Why?
Sperm Maturation12010220.090 Why?
Central Nervous System Diseases120145210.090 Why?
Recombinant Proteins3201765040.090 Why?
Isoenzymes1201416820.080 Why?
Antipyrine12009400.080 Why?
Tissue Inhibitor of Metalloproteinase-1120091510.080 Why?
Dipeptides120113860.080 Why?
Coagulants12009450.080 Why?
Up-Regulation2201541110.080 Why?
Cytochromes c120091730.080 Why?
Sperm Motility120102660.080 Why?
Free Radical Scavengers120092110.080 Why?
Benzimidazoles120148580.080 Why?
Iron1201717900.080 Why?
Reactive Oxygen Species3201421380.080 Why?
Aminolevulinic Acid120091450.080 Why?
Oxidation-Reduction1201422270.080 Why?
Active Transport, Cell Nucleus120104300.080 Why?
RNA, Small Interfering2201534120.080 Why?
Membrane Potential, Mitochondrial120092950.080 Why?
Hydrogen Peroxide220097310.080 Why?
Energy Metabolism1201928770.080 Why?
Collagenases120082220.070 Why?
Metabolic Diseases120146800.070 Why?
Models, Molecular2201654060.070 Why?
Cytoprotection120082000.070 Why?
Rats, Wistar3201718480.070 Why?
Blood Coagulation2201411560.070 Why?
Receptors, N-Methyl-D-Aspartate120128940.070 Why?
Infertility, Male120103960.070 Why?
Matrix Metalloproteinase 9220096310.070 Why?
Protein Conformation1201439330.070 Why?
Multienzyme Complexes120106650.070 Why?
Protein Transport1201219580.070 Why?
Gene Deletion1201326580.060 Why?
Membrane Proteins4200878510.060 Why?
Clone Cells1200916680.060 Why?
Hypoxia-Ischemia, Brain120093540.060 Why?
Cell Hypoxia320156560.060 Why?
Protein Isoforms1201016950.060 Why?
Tight Junctions120083240.060 Why?
Autophagy1201313270.060 Why?
Mammals2200511290.060 Why?
Neovascularization, Physiologic1201213470.060 Why?
Proto-Oncogene Proteins c-akt1201424550.060 Why?
Antigens, CD1201540090.060 Why?
Hydrocephalus119917640.060 Why?
TOR Serine-Threonine Kinases1201420580.060 Why?
Cholesterol2200529020.060 Why?
Photosensitizing Agents120096250.060 Why?
Saccharomyces cerevisiae2199426670.060 Why?
Cysteine Proteinase Inhibitors120051880.060 Why?
Microsomes320052510.060 Why?
Disease Progression32020135110.060 Why?
Cerebrovascular Circulation3202327250.060 Why?
Monitoring, Physiologic1199117800.060 Why?
Cell Death4201216760.060 Why?
Microsurgery120097930.060 Why?
Homeostasis1201433200.050 Why?
Rabbits2200147500.050 Why?
Ultrasonography, Interventional1201114960.050 Why?
Liver2202075140.050 Why?
Fluorescence220207510.050 Why?
Transferases12002710.050 Why?
Fertilization120041980.050 Why?
Hexosyltransferases12002580.050 Why?
Blotting, Western3201250320.050 Why?
Peptide Elongation Factor 112002390.050 Why?
Down-Regulation3201529160.050 Why?
Proto-Oncogene Proteins1201445130.050 Why?
L-Lactate Dehydrogenase220154100.050 Why?
RNA-Binding Proteins1201018550.050 Why?
Cell Transdifferentiation120221860.050 Why?
Nerve Tissue Proteins2201244040.050 Why?
Comorbidity12015105160.050 Why?
Muscle, Smooth, Vascular1200714880.040 Why?
Brefeldin A22004680.040 Why?
Endoplasmic Reticulum, Rough12000210.040 Why?
Arachidonic Acids120012940.040 Why?
Protein Synthesis Inhibitors220041890.040 Why?
Molecular Sequence Data52010175980.040 Why?
Heat-Shock Proteins120047950.040 Why?
Solubility2199810850.040 Why?
Rats, Sprague-Dawley4202181640.040 Why?
Structure-Activity Relationship2201630570.040 Why?
Polyisoprenyl Phosphate Monosaccharides1199830.040 Why?
High-Throughput Screening Assays220169310.040 Why?
Propyl Gallate1199810.040 Why?
Mitogen-Activated Protein Kinases1200412400.040 Why?
Lipodystrophy120201450.040 Why?
JNK Mitogen-Activated Protein Kinases120214380.040 Why?
Flow Cytometry1200958710.040 Why?
Cell Size120016250.040 Why?
Image Interpretation, Computer-Assisted1201133660.040 Why?
Adipocytes, Brown120191510.040 Why?
Carbohydrate Sequence219984110.040 Why?
Contrast Media1201153110.040 Why?
Imaging, Three-Dimensional1201140520.040 Why?
Liposomes219987830.040 Why?
Dogs2200238320.040 Why?
Multicenter Studies as Topic1202317020.040 Why?
Cytosol120018830.040 Why?
Cytoplasmic Granules120005730.040 Why?
Steroids120029290.040 Why?
Membrane Lipids119982510.040 Why?
Dendrites120004710.040 Why?
Dose-Response Relationship, Drug32016107560.030 Why?
Obesity12019129390.030 Why?
Translocation, Genetic1200213910.030 Why?
Models, Biological1201394570.030 Why?
Lipid Bilayers119983790.030 Why?
Stress, Physiological1200414050.030 Why?
Permeability119987210.030 Why?
Immunoglobulin G1200845370.030 Why?
Lens, Crystalline119983850.030 Why?
Sensitivity and Specificity12011146750.030 Why?
Adrenal Cortex Hormones1200518780.030 Why?
Neuroblastoma1200412460.030 Why?
Infant, Newborn22013261990.030 Why?
Guanosine 5'-O-(3-Thiotriphosphate)11994870.030 Why?
Hexosaminidases11994450.030 Why?
Spectroscopy, Near-Infrared120207400.030 Why?
Thermogenesis120194770.030 Why?
Female820243925440.030 Why?
Phosphorylation3201583000.030 Why?
Inflammation12014107590.030 Why?
Cyclopentanes11994870.030 Why?
Computer Simulation1200862240.030 Why?
Amino Acid Sequence32010134020.030 Why?
Erythrocytes2200124130.030 Why?
Neutrophil Infiltration120163900.030 Why?
Ribosomal Protein S612014710.030 Why?
Cell Line, Tumor42015169520.030 Why?
Glioblastoma1200934820.030 Why?
Unfolded Protein Response120152340.030 Why?
Receptor-Interacting Protein Serine-Threonine Kinases120141400.030 Why?
Aged320151692880.030 Why?
Hep G2 Cells120133740.030 Why?
Guinea Pigs2200513080.030 Why?
Dolichol Phosphates1199130.020 Why?
Ischemia2201218890.020 Why?
CHO Cells1199413790.020 Why?
Substrate Specificity1201617680.020 Why?
Pancreas1199816840.020 Why?
Monitoring, Intraoperative119989440.020 Why?
Memantine120121080.020 Why?
Myelin Sheath120156530.020 Why?
Molecular Structure1201618750.020 Why?
Coenzymes119911010.020 Why?
Glycosylation1199410950.020 Why?
Glycosyltransferases119911140.020 Why?
Receptors, Ionotropic Glutamate1201080.020 Why?
Cricetinae1199424120.020 Why?
Single-Blind Method1201415770.020 Why?
Species Specificity1199424060.020 Why?
Cerebrospinal Fluid Shunts119911950.020 Why?
Microscopy, Electron, Transmission120126960.020 Why?
Models, Chemical120126090.020 Why?
N-Methylaspartate120102300.020 Why?
Excitatory Amino Acid Antagonists120124460.020 Why?
Peptides1200243530.020 Why?
Liver Cirrhosis1202019320.020 Why?
Perfusion1199413900.020 Why?
Phagocytosis1201515250.020 Why?
Sodium Channel Blockers120101720.020 Why?
Middle Aged220152208530.020 Why?
Necrosis1201416100.020 Why?
Tetrodotoxin120102450.020 Why?
RNA, Messenger22005127470.020 Why?
Nitroprusside120092720.020 Why?
Nitric Oxide Donors120091260.020 Why?
Spermatogenesis120102570.020 Why?
HeLa Cells1201530730.020 Why?
Cardiovascular Diseases12014155200.020 Why?
Premedication120092460.020 Why?
Treatment Outcome22012646810.020 Why?
Microbial Collagenase120081120.020 Why?
Tomography, X-Ray Computed12011205880.020 Why?
Enzyme Activation1201435770.020 Why?
Membrane Potentials1201110880.020 Why?
Imidazoles1201411720.020 Why?
Blood Flow Velocity1199113750.020 Why?
Biological Transport2200520800.020 Why?
Brain Damage, Chronic120082660.020 Why?
Drug Design1201210450.020 Why?
Research Design1202361800.020 Why?
Injections, Intravenous1200913760.020 Why?
International Normalized Ratio120083820.020 Why?
Time Factors32014399570.020 Why?
Mice, Inbred Strains1200917620.020 Why?
Transfection1201457480.020 Why?
Tumor Cells, Cultured1201361240.020 Why?
Cytokines1202173860.020 Why?
Indoles1201418300.020 Why?
Infant, Premature, Diseases119917100.020 Why?
Microsomes, Liver219981720.020 Why?
Neuronal Plasticity1201414320.020 Why?
Brain-Derived Neurotrophic Factor120096020.020 Why?
Epithelium1201016030.020 Why?
Injections120088320.020 Why?
RNA Interference1201428160.020 Why?
Chronic Disease1202093190.020 Why?
Cell Fractionation120052480.020 Why?
Movement Disorders120084590.010 Why?
tau Proteins1201520940.010 Why?
Ubiquitin120098390.010 Why?
Thapsigargin120041020.010 Why?
Reproductive Techniques12004410.010 Why?
Nerve Growth Factors120075640.010 Why?
Animals, Newborn1200926650.010 Why?
Neuropilins12003120.010 Why?
Structural Homology, Protein12003870.010 Why?
Hematoma120087630.010 Why?
Magnetic Resonance Imaging32024364150.010 Why?
Semen120053470.010 Why?
Tumor Necrosis Factor-alpha1201443400.010 Why?
Swine2200559090.010 Why?
Enzyme-Linked Immunosorbent Assay1200938030.010 Why?
Testis120057810.010 Why?
Recombinant Fusion Proteins1201037260.010 Why?
Ribosomes120054940.010 Why?
Inheritance Patterns120043410.010 Why?
COS Cells1200311290.010 Why?
Analysis of Variance1200962230.010 Why?
Caspases120048780.010 Why?
Drug Administration Schedule1200948510.010 Why?
Oxygen1201242270.010 Why?
Administration, Oral1200840150.010 Why?
Organ Specificity1200519630.010 Why?
Hemoglobins1200615250.010 Why?
Prospective Studies12024544350.010 Why?
Electrophoresis, Polyacrylamide Gel1200217280.010 Why?
Dentate Gyrus120001650.010 Why?
Glucosyltransferases11998950.010 Why?
Trephining11998130.010 Why?
DNA, Mitochondrial120048650.010 Why?
Ultrasonography1199159690.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200545670.010 Why?
Protein Folding120028690.010 Why?
Kinetics2199863120.010 Why?
Protein Kinase Inhibitors1201456620.010 Why?
Cell Adhesion Molecules1200316030.010 Why?
Mice, Transgenic1200995200.010 Why?
Transducers119982440.010 Why?
Microscopy, Electron1200025610.010 Why?
Oligosaccharides119984060.010 Why?
Protein Structure, Tertiary1200337780.010 Why?
Phenotype12014165750.010 Why?
Case-Control Studies12013221740.010 Why?
Binding Sites1200359880.010 Why?
Guanosine Diphosphate Mannose1199140.010 Why?
Chlorophyta11991140.010 Why?
Uridine Diphosphate11991330.010 Why?
Isomerism119911970.010 Why?
Mass Spectrometry1199821890.010 Why?
Models, Theoretical1200335710.010 Why?
Carrier Proteins1200449350.010 Why?
Protein Binding1200292970.010 Why?
Phantoms, Imaging1199825130.010 Why?
Artifacts1199819120.010 Why?
Child, Preschool11991422240.000 Why?
Postoperative Complications12009156370.000 Why?
Cattle1199138180.000 Why?
Child11991801520.000 Why?
Adolescent11991882980.000 Why?
Image Processing, Computer-Assisted1199889980.000 Why?
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Concepts (385)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.