Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Klaus J. van Leyen, Ph.D.

Concepts (385)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Arachidonate 15-Lipoxygenase232021846.950 Why?
Arachidonate 12-Lipoxygenase182021825.630 Why?
Lipoxygenase Inhibitors132021932.850 Why?
Stroke20202497551.370 Why?
Brain Ischemia10201930071.310 Why?
Infarction, Middle Cerebral Artery520244861.120 Why?
Lipoxygenase32017720.920 Why?
Tissue Plasminogen Activator6202111650.890 Why?
Oxidative Stress10201931390.790 Why?
Naphthalenes220211980.760 Why?
Fibrinolytic Agents3201920800.750 Why?
Isoxazoles220212330.720 Why?
Neurons16201695140.700 Why?
Brain Injuries6201920570.680 Why?
Flavanones32010750.660 Why?
Oligodendroglia320155400.640 Why?
Thrombolytic Therapy3201920550.520 Why?
Lipoxygenases12014130.480 Why?
Apoptosis Inducing Factor22016510.480 Why?
Cerebral Hemorrhage7201926550.470 Why?
Semaphorin-3A22012390.470 Why?
STAT Transcription Factors120151890.470 Why?
Endoplasmic Reticulum11201011330.450 Why?
Warfarin4201714930.450 Why?
Intracranial Hemorrhages120198100.440 Why?
Neuroprotective Agents520209580.430 Why?
Organelles320012650.430 Why?
Echoencephalography220111340.410 Why?
Enzyme Inhibitors7201737280.390 Why?
Leukomalacia, Periventricular120131840.380 Why?
Fatty Acids, Unsaturated120145420.370 Why?
Subarachnoid Hemorrhage1201910240.370 Why?
Brain Edema420106010.350 Why?
Ultrasonography, Doppler, Color120112340.350 Why?
Ischemic Attack, Transient220238770.350 Why?
Mice382024820290.340 Why?
Ultrasonography, Doppler, Transcranial120112770.340 Why?
Brain112019273600.330 Why?
Animals6020241692460.320 Why?
Glutamic Acid4201711910.320 Why?
Reticulocytes320142870.310 Why?
Microglia3202113760.310 Why?
Blood-Brain Barrier5201910340.300 Why?
Apoptosis6201795230.300 Why?
Brain Infarction220212860.300 Why?
Cell Communication1201516600.300 Why?
Aspirin1201931350.290 Why?
Platelet Aggregation Inhibitors1201927630.290 Why?
Hemorrhage2201934670.280 Why?
Anticoagulants4201948520.270 Why?
Macrophages2201957990.270 Why?
Mice, Inbred C57BL152024223790.260 Why?
Mice, Knockout92019144880.260 Why?
Disease Models, Animal112024183490.240 Why?
Cell Nucleus2201028850.230 Why?
Reperfusion320212660.220 Why?
Mitochondria5201736810.210 Why?
Glycopeptides219942250.210 Why?
Drug Evaluation, Preclinical1200813380.210 Why?
Brain Diseases1201115540.200 Why?
Intracellular Membranes320053880.200 Why?
Neural Stem Cells220228950.200 Why?
Antioxidants2200816730.200 Why?
Intracranial Embolism220211880.190 Why?
Molecular Chaperones320157620.190 Why?
Lipofuscin12020400.180 Why?
Cold-Shock Response12019160.170 Why?
Hypoxia, Brain220211390.160 Why?
Cells, Cultured92022190150.150 Why?
Proteasome Endopeptidase Complex1200513190.150 Why?
Glycogen Synthase Kinase 3320154140.150 Why?
Astrocytes4202213500.150 Why?
Platelet Function Tests120192750.150 Why?
Hippocampus4201637850.140 Why?
Cell Line72019155970.140 Why?
Annexin A212017430.140 Why?
Endothelial Cells5202235890.140 Why?
Coronary Thrombosis120194400.130 Why?
Glucose6202143520.130 Why?
Recovery of Function2201629810.130 Why?
Drug Therapy, Combination3202163160.120 Why?
Cerebral Cortex4201658120.120 Why?
Rats122021237600.120 Why?
Male2920243647190.110 Why?
Review Literature as Topic120152970.110 Why?
Adrenal Cortex220051340.110 Why?
beta-Alanine12014820.110 Why?
Lipocalins120141610.110 Why?
Adipose Tissue, Brown120197760.110 Why?
Cytoplasm2201015050.110 Why?
Brain Neoplasms3201191180.110 Why?
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid12012150.110 Why?
Secondary Prevention1201914740.110 Why?
Acute-Phase Proteins120142520.110 Why?
Golgi Apparatus119944060.100 Why?
Spermatozoa320106320.100 Why?
Immunohistochemistry52013110950.100 Why?
Vesicular Transport Proteins120153770.100 Why?
Corpus Striatum2201612240.100 Why?
Capillary Permeability220177720.100 Why?
Oligopeptides2201411940.100 Why?
In Situ Nick-End Labeling120136110.100 Why?
Cerebrospinal Fluid Pressure11991380.100 Why?
Second Messenger Systems120122030.100 Why?
Toll-Like Receptor 4120155880.100 Why?
Liver Diseases1202013050.100 Why?
Arachidonic Acid120134290.090 Why?
Globins120124050.090 Why?
Reperfusion Injury2201510390.090 Why?
Leukotrienes120122320.090 Why?
Hydrogen Sulfide120121470.090 Why?
Blood Coagulation Factors220143710.090 Why?
Calcium2201757920.090 Why?
Glutathione220125890.090 Why?
Gene Knockdown Techniques1201516060.090 Why?
Head Injuries, Closed119911330.090 Why?
Epididymis220102270.090 Why?
Signal Transduction82015236450.090 Why?
Humans3520207681660.090 Why?
Sperm Maturation12010220.090 Why?
Central Nervous System Diseases120145200.090 Why?
Recombinant Proteins3201765140.090 Why?
Antipyrine12009400.080 Why?
Isoenzymes1201416880.080 Why?
Tissue Inhibitor of Metalloproteinase-1120091490.080 Why?
Dipeptides120113860.080 Why?
Coagulants12009450.080 Why?
Up-Regulation2201541460.080 Why?
Cytochromes c120091730.080 Why?
Sperm Motility120102650.080 Why?
Free Radical Scavengers120092130.080 Why?
Benzimidazoles120148640.080 Why?
Iron1201718130.080 Why?
Reactive Oxygen Species3201421490.080 Why?
Oxidation-Reduction1201422270.080 Why?
Active Transport, Cell Nucleus120104320.080 Why?
Membrane Potential, Mitochondrial120092970.080 Why?
RNA, Small Interfering2201534280.080 Why?
Aminolevulinic Acid120091480.080 Why?
Hydrogen Peroxide220097400.080 Why?
Energy Metabolism1201929070.070 Why?
Collagenases120082210.070 Why?
Metabolic Diseases120146840.070 Why?
Models, Molecular2201654030.070 Why?
Cytoprotection120082000.070 Why?
Blood Coagulation2201411620.070 Why?
Rats, Wistar3201718880.070 Why?
Infertility, Male120103970.070 Why?
Receptors, N-Methyl-D-Aspartate120129030.070 Why?
Matrix Metalloproteinase 9220096330.070 Why?
Protein Conformation1201439560.070 Why?
Multienzyme Complexes120106640.070 Why?
Protein Transport1201219510.070 Why?
Gene Deletion1201326750.060 Why?
Membrane Proteins4200878760.060 Why?
Clone Cells1200916700.060 Why?
Cell Hypoxia320156620.060 Why?
Hypoxia-Ischemia, Brain120093590.060 Why?
Tight Junctions120083240.060 Why?
Protein Isoforms1201017150.060 Why?
Autophagy1201313490.060 Why?
Mammals2200511350.060 Why?
Neovascularization, Physiologic1201213690.060 Why?
Proto-Oncogene Proteins c-akt1201424570.060 Why?
Hydrocephalus119917680.060 Why?
Antigens, CD1201540350.060 Why?
TOR Serine-Threonine Kinases1201420620.060 Why?
Photosensitizing Agents120096290.060 Why?
Cholesterol2200529140.060 Why?
Cysteine Proteinase Inhibitors120051850.060 Why?
Saccharomyces cerevisiae2199426820.060 Why?
Microsomes320052520.060 Why?
Disease Progression32020136710.060 Why?
Cerebrovascular Circulation3202327250.060 Why?
Monitoring, Physiologic1199117980.060 Why?
Cell Death4201216790.060 Why?
Microsurgery120098000.050 Why?
Rabbits2200147720.050 Why?
Homeostasis1201433480.050 Why?
Liver2202075770.050 Why?
Fluorescence220207560.050 Why?
Ultrasonography, Interventional1201115230.050 Why?
Transferases12002710.050 Why?
Fertilization120041970.050 Why?
Hexosyltransferases12002580.050 Why?
Blotting, Western3201250270.050 Why?
Peptide Elongation Factor 112002400.050 Why?
Down-Regulation3201529370.050 Why?
Proto-Oncogene Proteins1201445280.050 Why?
L-Lactate Dehydrogenase220154120.050 Why?
Cell Transdifferentiation120221860.050 Why?
RNA-Binding Proteins1201018900.050 Why?
Nerve Tissue Proteins2201244130.050 Why?
Comorbidity12015105900.040 Why?
Muscle, Smooth, Vascular1200714930.040 Why?
Brefeldin A22004680.040 Why?
Endoplasmic Reticulum, Rough12000210.040 Why?
Arachidonic Acids120012960.040 Why?
Protein Synthesis Inhibitors220041880.040 Why?
Molecular Sequence Data52010176220.040 Why?
Heat-Shock Proteins120047970.040 Why?
Solubility2199810830.040 Why?
Rats, Sprague-Dawley4202181280.040 Why?
Structure-Activity Relationship2201630550.040 Why?
Polyisoprenyl Phosphate Monosaccharides1199830.040 Why?
High-Throughput Screening Assays220169420.040 Why?
Propyl Gallate1199810.040 Why?
Lipodystrophy120201450.040 Why?
Mitogen-Activated Protein Kinases1200412450.040 Why?
JNK Mitogen-Activated Protein Kinases120214400.040 Why?
Cell Size120016260.040 Why?
Flow Cytometry1200959020.040 Why?
Image Interpretation, Computer-Assisted1201133900.040 Why?
Carbohydrate Sequence219984110.040 Why?
Adipocytes, Brown120191600.040 Why?
Contrast Media1201153300.040 Why?
Imaging, Three-Dimensional1201140630.040 Why?
Liposomes219987900.040 Why?
Dogs2200238450.040 Why?
Cytosol120018870.040 Why?
Multicenter Studies as Topic1202317370.040 Why?
Cytoplasmic Granules120005740.040 Why?
Steroids120029380.040 Why?
Membrane Lipids119982520.040 Why?
Dendrites120004720.040 Why?
Dose-Response Relationship, Drug32016107600.030 Why?
Obesity12019130900.030 Why?
Translocation, Genetic1200213940.030 Why?
Lipid Bilayers119983790.030 Why?
Models, Biological1201394950.030 Why?
Stress, Physiological1200414080.030 Why?
Permeability119987250.030 Why?
Lens, Crystalline119983870.030 Why?
Immunoglobulin G1200845680.030 Why?
Sensitivity and Specificity12011147290.030 Why?
Adrenal Cortex Hormones1200518860.030 Why?
Neuroblastoma1200412660.030 Why?
Infant, Newborn22013264220.030 Why?
Guanosine 5'-O-(3-Thiotriphosphate)11994870.030 Why?
Hexosaminidases11994450.030 Why?
Spectroscopy, Near-Infrared120207520.030 Why?
Thermogenesis120194940.030 Why?
Phosphorylation3201583170.030 Why?
Female820243971920.030 Why?
Inflammation12014108730.030 Why?
Cyclopentanes11994870.030 Why?
Amino Acid Sequence32010134210.030 Why?
Computer Simulation1200862830.030 Why?
Erythrocytes2200124180.030 Why?
Ribosomal Protein S612014700.030 Why?
Neutrophil Infiltration120163930.030 Why?
Glioblastoma1200934640.030 Why?
Cell Line, Tumor42015171400.030 Why?
Unfolded Protein Response120152390.030 Why?
Aged320151715040.030 Why?
Receptor-Interacting Protein Serine-Threonine Kinases120141460.030 Why?
Hep G2 Cells120133780.030 Why?
Guinea Pigs2200513100.020 Why?
Dolichol Phosphates1199130.020 Why?
Ischemia2201219000.020 Why?
Substrate Specificity1201617510.020 Why?
CHO Cells1199413790.020 Why?
Monitoring, Intraoperative119989480.020 Why?
Pancreas1199817000.020 Why?
Myelin Sheath120156520.020 Why?
Molecular Structure1201618830.020 Why?
Memantine120121110.020 Why?
Coenzymes119911010.020 Why?
Glycosylation1199411000.020 Why?
Glycosyltransferases119911140.020 Why?
Receptors, Ionotropic Glutamate1201080.020 Why?
Cricetinae1199424230.020 Why?
Single-Blind Method1201415870.020 Why?
Cerebrospinal Fluid Shunts119911970.020 Why?
Microscopy, Electron, Transmission120126870.020 Why?
Species Specificity1199424150.020 Why?
Models, Chemical120126110.020 Why?
N-Methylaspartate120102310.020 Why?
Excitatory Amino Acid Antagonists120124510.020 Why?
Peptides1200243540.020 Why?
Phagocytosis1201515300.020 Why?
Liver Cirrhosis1202019600.020 Why?
Perfusion1199414010.020 Why?
Sodium Channel Blockers120101730.020 Why?
Necrosis1201416160.020 Why?
Tetrodotoxin120102430.020 Why?
Middle Aged220152234920.020 Why?
Nitroprusside120092720.020 Why?
RNA, Messenger22005128000.020 Why?
Nitric Oxide Donors120091260.020 Why?
Spermatogenesis120102600.020 Why?
HeLa Cells1201530740.020 Why?
Cardiovascular Diseases12014156620.020 Why?
Premedication120092460.020 Why?
Treatment Outcome22012653710.020 Why?
Microbial Collagenase120081120.020 Why?
Tomography, X-Ray Computed12011207600.020 Why?
Enzyme Activation1201435900.020 Why?
Membrane Potentials1201110900.020 Why?
Imidazoles1201411690.020 Why?
Blood Flow Velocity1199113750.020 Why?
Biological Transport2200520850.020 Why?
Brain Damage, Chronic120082650.020 Why?
Drug Design1201210460.020 Why?
Research Design1202362110.020 Why?
Injections, Intravenous1200913770.020 Why?
International Normalized Ratio120083820.020 Why?
Time Factors32014402180.020 Why?
Mice, Inbred Strains1200917650.020 Why?
Transfection1201457550.020 Why?
Tumor Cells, Cultured1201361240.020 Why?
Cytokines1202174530.020 Why?
Infant, Premature, Diseases119917120.020 Why?
Indoles1201418360.020 Why?
Microsomes, Liver219981740.020 Why?
Brain-Derived Neurotrophic Factor120096050.020 Why?
Neuronal Plasticity1201414480.020 Why?
Epithelium1201016070.020 Why?
Injections120088400.020 Why?
RNA Interference1201428320.020 Why?
Chronic Disease1202093840.020 Why?
Cell Fractionation120052470.010 Why?
Movement Disorders120084630.010 Why?
tau Proteins1201521440.010 Why?
Thapsigargin120041020.010 Why?
Ubiquitin120098430.010 Why?
Reproductive Techniques12004410.010 Why?
Nerve Growth Factors120075640.010 Why?
Animals, Newborn1200926780.010 Why?
Neuropilins12003120.010 Why?
Structural Homology, Protein12003860.010 Why?
Hematoma120087660.010 Why?
Magnetic Resonance Imaging32024367430.010 Why?
Semen120053490.010 Why?
Tumor Necrosis Factor-alpha1201443520.010 Why?
Enzyme-Linked Immunosorbent Assay1200938140.010 Why?
Swine2200559950.010 Why?
Testis120057830.010 Why?
Recombinant Fusion Proteins1201037400.010 Why?
Ribosomes120054970.010 Why?
Inheritance Patterns120043440.010 Why?
COS Cells1200311350.010 Why?
Analysis of Variance1200962290.010 Why?
Drug Administration Schedule1200948600.010 Why?
Caspases120048820.010 Why?
Oxygen1201242700.010 Why?
Administration, Oral1200840300.010 Why?
Organ Specificity1200519680.010 Why?
Hemoglobins1200615310.010 Why?
Prospective Studies12024549260.010 Why?
Electrophoresis, Polyacrylamide Gel1200217300.010 Why?
Dentate Gyrus120001650.010 Why?
Glucosyltransferases11998940.010 Why?
Trephining11998180.010 Why?
DNA, Mitochondrial120048720.010 Why?
Ultrasonography1199160040.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200545800.010 Why?
Protein Folding120028710.010 Why?
Kinetics2199863290.010 Why?
Protein Kinase Inhibitors1201457030.010 Why?
Cell Adhesion Molecules1200316130.010 Why?
Mice, Transgenic1200995610.010 Why?
Transducers119982430.010 Why?
Microscopy, Electron1200025600.010 Why?
Oligosaccharides119984070.010 Why?
Protein Structure, Tertiary1200337720.010 Why?
Phenotype12014167260.010 Why?
Case-Control Studies12013222910.010 Why?
Binding Sites1200360200.010 Why?
Guanosine Diphosphate Mannose1199140.010 Why?
Chlorophyta11991150.010 Why?
Uridine Diphosphate11991350.010 Why?
Isomerism119911980.010 Why?
Models, Theoretical1200335730.010 Why?
Mass Spectrometry1199822020.010 Why?
Carrier Proteins1200449370.010 Why?
Protein Binding1200293430.010 Why?
Phantoms, Imaging1199825120.010 Why?
Artifacts1199819260.010 Why?
Child, Preschool11991426690.000 Why?
Postoperative Complications12009158320.000 Why?
Cattle1199138190.000 Why?
Child11991809170.000 Why?
Adolescent11991891690.000 Why?
Image Processing, Computer-Assisted1199890150.000 Why?
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Concepts (385)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.