Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Michael Joseph Eck, M.D., Ph.D.

Concepts (582)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Models, Molecular67202453282.440 Why?
Crystallography, X-Ray44202419492.410 Why?
Protein Kinase Inhibitors35202455482.220 Why?
Protein Conformation42202139371.900 Why?
Proto-Oncogene Proteins B-raf5202320251.660 Why?
Microfilament Proteins8201711201.450 Why?
Focal Adhesion Protein-Tyrosine Kinases820141771.440 Why?
Protein Structure, Tertiary35201437741.370 Why?
src Homology Domains1820163621.170 Why?
Janus Kinase 2620195311.160 Why?
Actins8201720761.100 Why?
Mutation412024294061.080 Why?
Drug Resistance, Neoplasm17202451350.990 Why?
Adenosine Triphosphate10202419730.940 Why?
Amino Acid Sequence542017135380.930 Why?
Lung Neoplasms262024130330.920 Why?
ras Proteins3202210480.900 Why?
Protein Binding44202092240.890 Why?
Binding Sites36202460090.860 Why?
Protein-Tyrosine Kinases17201524240.850 Why?
Molecular Sequence Data522015177540.810 Why?
MAP Kinase Signaling System4202314840.800 Why?
Protein Structure, Secondary15202012270.800 Why?
Phosphorylation34202282670.780 Why?
14-3-3 Proteins320222210.750 Why?
Benzeneacetamides22019370.720 Why?
Cryoelectron Microscopy220235910.710 Why?
src-Family Kinases1220155330.710 Why?
MAP Kinase Kinase Kinases120212580.710 Why?
Saccharomyces cerevisiae Proteins6201518480.680 Why?
Intracellular Signaling Peptides and Proteins12202228440.680 Why?
Adaptor Proteins, Signal Transducing8201728620.670 Why?
MAP Kinase Kinase 1120193290.610 Why?
Antineoplastic Agents222024134780.600 Why?
Mutant Proteins320164880.590 Why?
Imidazoles2202111720.590 Why?
Receptor Protein-Tyrosine Kinases6202116470.590 Why?
Quinazolines12202213450.580 Why?
Carcinoma, Non-Small-Cell Lung13202352280.570 Why?
Carrier Proteins10201449060.570 Why?
Protein Multimerization820199550.560 Why?
Dimerization1320138850.550 Why?
Proto-Oncogene Proteins p21(ras)2202316750.540 Why?
Drug Design5202110490.490 Why?
TYK2 Kinase22014380.490 Why?
Sequence Homology, Amino Acid14201227760.490 Why?
Signal Transduction342022229520.480 Why?
Immunoglobulins620048620.480 Why?
Macrocyclic Compounds12024730.470 Why?
Allosteric Regulation720214080.460 Why?
High-Throughput Screening Assays120199210.450 Why?
Enzyme Activation13202136060.440 Why?
Proto-Oncogene Proteins pp60(c-src)519991460.440 Why?
Thiazoles3201914860.440 Why?
Cell Proliferation112019102500.430 Why?
Sequence Alignment13201622060.420 Why?
Janus Kinases120132390.420 Why?
Molecular Structure8202418710.410 Why?
Protein Phosphatase 1120221350.400 Why?
Protein Processing, Post-Translational4201519480.400 Why?
Oogenesis120111240.370 Why?
Pyrimidines7202429730.370 Why?
rho GTP-Binding Proteins320072790.370 Why?
Molecular Dynamics Simulation120133930.360 Why?
Glycoproteins7200422110.360 Why?
Staurosporine320072470.360 Why?
Protein Isoforms6202316880.360 Why?
Protein Tyrosine Phosphatases520214600.350 Why?
Phosphatidylinositols220082890.350 Why?
Trans-Activators5200428530.350 Why?
Interferon-alpha120148950.350 Why?
rho-Associated Kinases120112720.340 Why?
Saccharomyces cerevisiae4201526770.340 Why?
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)52003920.340 Why?
Cell Line, Tumor252023164630.330 Why?
Oncogenes2202212170.330 Why?
Nuclear Proteins6202157350.330 Why?
Proto-Oncogene Proteins11200545010.320 Why?
Molecular Targeted Therapy2201927290.320 Why?
Ubiquitination120139900.310 Why?
Animals6620231654790.310 Why?
Protein Structure, Quaternary320044300.310 Why?
Acrylamides320212580.300 Why?
Cytoskeletal Proteins3200513400.300 Why?
Aniline Compounds3202210160.300 Why?
Phosphotyrosine620154530.290 Why?
Multiprotein Complexes2202211100.280 Why?
Tyrosine7201114390.280 Why?
Fusion Proteins, bcr-abl120094280.280 Why?
Fetal Proteins12007960.280 Why?
Macromolecular Substances6201614400.280 Why?
Focal Adhesions220111160.280 Why?
Drosophila Proteins3201116950.270 Why?
Phosphoproteins6200023870.260 Why?
Morpholines120085600.260 Why?
Lymphoproliferative Disorders420035260.260 Why?
Humans10720247354580.250 Why?
Tumor Suppressor Proteins1201527820.250 Why?
Small Cell Lung Carcinoma120093910.250 Why?
Structure-Activity Relationship9202430680.250 Why?
PTEN Phosphohydrolase3202111110.250 Why?
Genetic Variation1202064120.240 Why?
Receptor, erbB-25202224470.240 Why?
Phosphopeptides519992400.240 Why?
Zinc320036780.240 Why?
Mutagenesis, Insertional320176470.230 Why?
Prokaryotic Cells12003470.230 Why?
Protein Interaction Domains and Motifs320154470.220 Why?
Amino Acid Motifs720109190.220 Why?
Adhesins, Bacterial120031190.220 Why?
Proto-Oncogene Proteins c-akt2202224380.210 Why?
Transcription Factors82016119490.210 Why?
HMGB Proteins12001440.200 Why?
Drug Resistance1200815840.200 Why?
Tryptophan220014740.200 Why?
Anthranilate Synthase1200150.200 Why?
Enzyme Stability120212130.190 Why?
Janus Kinase 322015770.190 Why?
Peptides7201642920.190 Why?
Exons5202223860.190 Why?
Mitosis3201612040.190 Why?
Allosteric Site220211000.190 Why?
Nerve Tissue Proteins2201143780.180 Why?
Protein Kinases3202416100.180 Why?
Muscle, Skeletal1201547750.180 Why?
Neoplasms52023213750.180 Why?
Substrate Specificity9201517740.180 Why?
Homeostasis1201032560.170 Why?
Cloning, Molecular6201542150.170 Why?
Class Ia Phosphatidylinositol 3-Kinase22017750.170 Why?
NIH 3T3 Cells720196710.170 Why?
Genes, erbB-1220131600.170 Why?
Mice312023795480.170 Why?
Dystrophin120002870.170 Why?
Adenosine Triphosphatases120038300.160 Why?
Clathrin120202660.160 Why?
Ubiquitin-Protein Ligases4201018280.160 Why?
Receptors, Cell Surface8200428050.160 Why?
Salmonella typhimurium120013500.160 Why?
Adaptor Proteins, Vesicular Transport120203030.160 Why?
Pyrazoles3201619730.160 Why?
Foodborne Diseases12018370.160 Why?
Serine Endopeptidases1200310540.150 Why?
Gene Expression6201775780.150 Why?
Food Analysis120181030.150 Why?
Static Electricity220122580.150 Why?
Salmonella120181280.150 Why?
Cytokinesis220101760.150 Why?
Receptors, Mitogen22011610.150 Why?
Birds220081650.150 Why?
Phosphatidylinositol 4,5-Diphosphate320141260.150 Why?
Fluorescence Polarization220211330.150 Why?
GTPase-Activating Proteins120204800.140 Why?
Protein Subunits320229470.140 Why?
Salmonella Infections120181700.140 Why?
Cell Transformation, Neoplastic4202328140.140 Why?
Acoustics120182390.140 Why?
Fluorobenzenes120181800.140 Why?
Enzyme Inhibitors6201236860.140 Why?
Mutagenesis, Site-Directed5201716950.140 Why?
Eukaryotic Initiation Factors12016910.140 Why?
Molecular Conformation320175470.140 Why?
Shc Signaling Adaptor Proteins12015450.140 Why?
Hedgehog Proteins120217620.130 Why?
Benzamides2201413600.130 Why?
Escherichia coli9201541660.130 Why?
Antigens, CD7200438830.130 Why?
Receptors, Antigen, T-Cell2200324950.130 Why?
Adenocarcinoma5201462570.130 Why?
Recombinant Proteins6201565110.130 Why?
Drug Discovery2202110330.130 Why?
Lymphocyte Activation2200353830.130 Why?
Cell Line102019156170.130 Why?
Cell Division3202144470.130 Why?
Rabbits2201548260.130 Why?
Cell Membrane2202336850.130 Why?
Hydrogen Bonding520122920.130 Why?
Ligands3201932480.130 Why?
Drug Resistance, Multiple120162530.130 Why?
Milk120184360.130 Why?
Drug Synergism2201617310.130 Why?
Calorimetry220061260.120 Why?
Recombinant Fusion Proteins5201237120.120 Why?
Receptor, IGF Type 1120173690.120 Why?
Amino Acid Substitution6201717450.120 Why?
Quinolines320167310.120 Why?
Conserved Sequence3201611690.120 Why?
Neurogenesis120218340.120 Why?
Crystallization220135140.120 Why?
Thermodynamics120155870.110 Why?
Cytoplasm3201015060.110 Why?
Cerebellum1202114670.110 Why?
Publications120161930.110 Why?
Neural Stem Cells120218580.110 Why?
Biosensing Techniques220186470.110 Why?
Proteins5201659750.110 Why?
Point Mutation6201115940.110 Why?
T-Lymphocytes4200499520.110 Why?
Autocrine Communication120141670.110 Why?
Cell Adhesion3201430910.110 Why?
Tandem Mass Spectrometry2201611400.110 Why?
Poly(ADP-ribose) Polymerases120144250.110 Why?
Binding, Competitive2201211370.110 Why?
Receptor, Insulin119968300.100 Why?
Membrane Glycoproteins2200036720.100 Why?
raf Kinases120221160.100 Why?
Repressor Proteins1200329550.100 Why?
Structural Homology, Protein22013850.100 Why?
Resorcinols12012380.100 Why?
Cell Polarity220076290.100 Why?
Interferon Regulatory Factor-3120131320.100 Why?
Muscle Proteins1201711320.100 Why?
Models, Chemical320096190.100 Why?
Drosophila melanogaster2201116980.100 Why?
I-kappa B Kinase120132430.100 Why?
Cell Survival5201957580.100 Why?
Leukemia, B-Cell12012830.100 Why?
Aminopyridines120155460.100 Why?
Guanosine Triphosphate120223170.100 Why?
Schiff Bases12010210.100 Why?
DNA-Binding Proteins4201494720.100 Why?
rac GTP-Binding Proteins120111600.100 Why?
Cyclic GMP120124000.090 Why?
Tropomyosin120111010.090 Why?
Mutation, Missense5201325020.090 Why?
Hypoxia-Inducible Factor 1, alpha Subunit320046070.090 Why?
Nuclear Magnetic Resonance, Biomolecular220035040.090 Why?
Peptide Library420163490.090 Why?
Isoxazoles120122220.090 Why?
Retroviridae220128490.090 Why?
Neoplasms, Muscle Tissue12010830.090 Why?
Benzimidazoles120158440.090 Why?
Tumor Necrosis Factor-alpha3199443190.090 Why?
Crystallography320051100.090 Why?
Lunate Bone12009370.090 Why?
Profilins22007650.090 Why?
Triangular Fibrocartilage12009270.090 Why?
Cell Physiological Phenomena120101520.080 Why?
Protein Folding220038340.080 Why?
Proto-Oncogene Proteins c-fyn320041130.080 Why?
Protein Biosynthesis1201620830.080 Why?
HSP90 Heat-Shock Proteins120124260.080 Why?
Databases, Genetic1201617230.080 Why?
Models, Anatomic120126760.080 Why?
Xenograft Model Antitumor Assays4201934890.080 Why?
Scaphoid Bone12009820.080 Why?
Genes, Reporter2200315260.080 Why?
Proteomics2202336180.080 Why?
Cell Cycle Proteins3201034010.080 Why?
Dose-Response Relationship, Drug42024106900.080 Why?
Dexamethasone1201519150.080 Why?
BRCA1 Protein1201411100.080 Why?
Cadherins220038820.080 Why?
Two-Hybrid System Techniques320044560.080 Why?
Gene Deletion1201526770.070 Why?
Catalytic Domain120096860.070 Why?
Cell Movement3201251330.070 Why?
Affinity Labels120071070.070 Why?
MicroRNAs1202336900.070 Why?
Integrins220208420.070 Why?
Membrane Proteins4201277480.070 Why?
Hydrophobic and Hydrophilic Interactions220103950.070 Why?
Wrist Injuries120092080.070 Why?
Circular Dichroism320033430.070 Why?
Leukemia1201514760.070 Why?
Ligaments, Articular120093020.070 Why?
Bronchial Neoplasms120071110.070 Why?
Lymphoma1201518510.070 Why?
HeLa Cells3202030440.070 Why?
Precursor Cell Lymphoblastic Leukemia-Lymphoma1201515070.070 Why?
SH2 Domain-Containing Protein Tyrosine Phosphatases42001450.070 Why?
Proline220004580.070 Why?
Blood Proteins2200511250.070 Why?
Cell Nucleus2201628840.070 Why?
Peptide Fragments7201449680.070 Why?
Neuropeptides120119390.070 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 6420011220.070 Why?
Transduction, Genetic120088940.070 Why?
Myeloproliferative Disorders120126050.060 Why?
Hydatidiform Mole, Invasive1200540.060 Why?
Glycine120086580.060 Why?
DNA Repair1201419970.060 Why?
Immunoblotting3201316520.060 Why?
Receptors, Immunologic2200314240.060 Why?
Proto-Oncogene Proteins c-cbl320001190.060 Why?
Repetitive Sequences, Amino Acid22001920.060 Why?
Oligopeptides1201011860.060 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11420012240.060 Why?
Melanoma1202355260.060 Why?
Codon220176030.060 Why?
Vaginal Neoplasms120051050.060 Why?
Transfection4201157800.060 Why?
Thrombocythemia, Essential120051030.060 Why?
Radius Fractures120095040.060 Why?
X-Ray Diffraction320014160.060 Why?
HEK293 Cells3202040980.060 Why?
Purines120075880.060 Why?
Polycythemia Vera120051610.060 Why?
Chickens120058510.060 Why?
Aminopeptidases12003880.060 Why?
Endopeptidase Clp12003460.060 Why?
Sequence Analysis, Protein120042530.060 Why?
Qc-SNARE Proteins12003200.060 Why?
Qb-SNARE Proteins12003350.060 Why?
Phosphoserine120032030.060 Why?
Green Fluorescent Proteins1200820360.060 Why?
Morphogenesis120077380.050 Why?
Gene Knockout Techniques220177760.050 Why?
Disease Models, Animal32017177000.050 Why?
Phosphotransferases (Alcohol Group Acceptor)220144320.050 Why?
Arthroscopy120099420.050 Why?
Primary Myelofibrosis120052180.050 Why?
Mice, Knockout32008141470.050 Why?
Insulin1201763930.050 Why?
Transcription Factor 7-Like 1 Protein12001230.050 Why?
Receptors, Aryl Hydrocarbon120042010.050 Why?
Endocytosis120079840.050 Why?
Asparagine120021180.050 Why?
Ciona intestinalis12021110.050 Why?
Epithelial Cells1201436350.050 Why?
ZAP-70 Protein-Tyrosine Kinase21999670.050 Why?
Kinetics2200863540.050 Why?
Sulfolobus1200150.050 Why?
Magnetic Resonance Spectroscopy2202137380.050 Why?
Azepines120033280.050 Why?
TCF Transcription Factors120011370.050 Why?
Transcription Factor 7-Like 2 Protein120011520.050 Why?
Dipeptides120034050.050 Why?
Gene Knockdown Techniques2201716040.050 Why?
EF Hand Motifs12000130.050 Why?
Microtubules1200710770.050 Why?
Dystroglycans12000580.050 Why?
Retroviridae Proteins, Oncogenic12000760.050 Why?
Amino Acids3201417160.050 Why?
Epitope Mapping120012990.050 Why?
Genes, ras120236500.050 Why?
Glioma1201533490.050 Why?
Quinazolinones120222240.050 Why?
Immunity, Innate1201229540.040 Why?
Breast Neoplasms32017205170.040 Why?
Antigen-Presenting Cells120039390.040 Why?
Receptors, Tumor Necrosis Factor219945770.040 Why?
Blood Coagulation Factors120013540.040 Why?
Receptors, Virus120036280.040 Why?
Intercellular Adhesion Molecule-11200311320.040 Why?
Disulfides220044570.040 Why?
Ligases120003300.040 Why?
Xenopus Proteins120014190.040 Why?
Mice, Nude3201235800.040 Why?
Pyridines1201027630.040 Why?
Receptors, Transferrin120202900.040 Why?
Receptors, LDL120014620.040 Why?
Epidermal Growth Factor120016940.040 Why?
Piperazines1200924610.040 Why?
Phenols120224960.040 Why?
Protein Engineering120025270.040 Why?
Food Microbiology12018770.040 Why?
RNA, Small Interfering3201634210.040 Why?
Insulin Receptor Substrate Proteins219995540.040 Why?