Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Michael Joseph Eck, M.D., Ph.D.

Concepts (591)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Kinase Inhibitors37202457072.680 Why?
Models, Molecular68202454042.430 Why?
Crystallography, X-Ray44202419522.270 Why?
Protein Conformation42202139561.850 Why?
Proto-Oncogene Proteins B-raf5202320591.610 Why?
Microfilament Proteins8201711351.410 Why?
Focal Adhesion Protein-Tyrosine Kinases820141851.380 Why?
ras Proteins4202410581.360 Why?
Protein Structure, Tertiary35201437751.330 Why?
src Homology Domains1820163611.130 Why?
Janus Kinase 2620195601.120 Why?
Mutation422024302661.080 Why?
Actins8201720651.070 Why?
Drug Resistance, Neoplasm18202453421.060 Why?
Adenosine Triphosphate11202420031.010 Why?
Lung Neoplasms272024135940.990 Why?
raf Kinases220241170.950 Why?
Amino Acid Sequence542017134270.910 Why?
Macrocyclic Compounds12024670.910 Why?
Binding Sites36202460230.890 Why?
14-3-3 Proteins420242220.890 Why?
Protein Binding44202093440.860 Why?
Protein-Tyrosine Kinases17201524330.820 Why?
Exons6202423950.800 Why?
Molecular Sequence Data522015176290.800 Why?
Protein Structure, Secondary15202012160.770 Why?
Phosphorylation34202283170.760 Why?
MAP Kinase Signaling System4202314950.740 Why?
Benzeneacetamides22019360.700 Why?
MAP Kinase Kinase Kinases120212520.680 Why?
src-Family Kinases1220155390.680 Why?
Saccharomyces cerevisiae Proteins6201518390.660 Why?
Adaptor Proteins, Signal Transducing8201729110.660 Why?
Cryoelectron Microscopy220236490.650 Why?
Signal Transduction352024236530.640 Why?
Carcinoma, Non-Small-Cell Lung14202454340.620 Why?
Antineoplastic Agents222024136980.610 Why?
MAP Kinase Kinase 1120193310.590 Why?
Receptor Protein-Tyrosine Kinases6202116290.570 Why?
Imidazoles2202111690.570 Why?
Mutant Proteins320164880.570 Why?
Quinazolines12202213730.560 Why?
Intracellular Signaling Peptides and Proteins12202228930.560 Why?
Carrier Proteins10201449390.550 Why?
Protein Multimerization820199680.540 Why?
Dimerization1320138860.530 Why?
Proto-Oncogene Proteins p21(ras)2202317690.510 Why?
Molecular Structure8202418850.480 Why?
Drug Design5202110460.480 Why?
Sequence Homology, Amino Acid14201227490.470 Why?
TYK2 Kinase22014380.470 Why?
Immunoglobulins620048550.470 Why?
Allosteric Regulation720214240.440 Why?
High-Throughput Screening Assays120199420.430 Why?
Enzyme Activation13202135880.430 Why?
Proto-Oncogene Proteins pp60(c-src)519991470.430 Why?
Thiazoles3201915420.420 Why?
Cell Proliferation112019104860.420 Why?
Mutagenesis, Insertional420246620.410 Why?
Sequence Alignment13201621790.410 Why?
Janus Kinases120132530.400 Why?
Protein Processing, Post-Translational4201519660.390 Why?
Oogenesis120111250.360 Why?
Structure-Activity Relationship10202430570.360 Why?
Pyrimidines7202430480.360 Why?
rho GTP-Binding Proteins320072790.350 Why?
Glycoproteins7200422020.350 Why?
Staurosporine320072410.350 Why?
Trans-Activators5200428580.340 Why?
Protein Tyrosine Phosphatases520214580.340 Why?
Phosphatidylinositols220082800.340 Why?
Molecular Dynamics Simulation120134270.340 Why?
Interferon-alpha120149100.340 Why?
Animals6820251693350.330 Why?
Saccharomyces cerevisiae4201526820.330 Why?
rho-Associated Kinases120112850.320 Why?
Oncogenes2202212360.320 Why?
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)52003930.320 Why?
Cell Line, Tumor252023171730.320 Why?
Nuclear Proteins6202158040.320 Why?
Proto-Oncogene Proteins11200545280.310 Why?
Protein Isoforms6202317140.310 Why?
Molecular Targeted Therapy2201928300.310 Why?
Ubiquitination1201310100.300 Why?
Protein Structure, Quaternary320044260.300 Why?
Acrylamides320212610.290 Why?
Cytoskeletal Proteins3200513280.290 Why?
Phosphotyrosine620154580.280 Why?
Aniline Compounds3202210950.270 Why?
Tyrosine7201114270.270 Why?
Humans11120257689700.270 Why?
Fusion Proteins, bcr-abl120094300.270 Why?
Focal Adhesions220111140.270 Why?
Fetal Proteins120071000.270 Why?
Macromolecular Substances6201614350.270 Why?
Drosophila Proteins3201117120.260 Why?
Phosphoproteins6200024520.250 Why?
Morpholines120085840.250 Why?
Lymphoproliferative Disorders420035290.250 Why?
Tumor Suppressor Proteins1201528120.240 Why?
PTEN Phosphohydrolase3202111200.240 Why?
Genetic Variation1202066110.240 Why?
Allosteric Site320241050.240 Why?
Small Cell Lung Carcinoma120094540.230 Why?
Phosphopeptides519992400.230 Why?
Zinc320036770.230 Why?
Receptor, erbB-25202226060.220 Why?
Protein Interaction Domains and Motifs320154500.220 Why?
Mitochondrial Membrane Transport Proteins120251700.220 Why?
Prokaryotic Cells12003530.220 Why?
Amino Acid Motifs720109300.210 Why?
Adhesins, Bacterial120031180.210 Why?
Proto-Oncogene Proteins c-akt2202224600.200 Why?
Transcription Factors82016121740.200 Why?
Neoplasms62024223890.200 Why?
HMGB Proteins12001450.200 Why?
Protein Phosphatase 1120221350.190 Why?
Drug Resistance1200815990.190 Why?
Tryptophan220014820.190 Why?
Anthranilate Synthase1200150.190 Why?
Enzyme Stability120212190.190 Why?
Peptides7201643530.180 Why?
Janus Kinase 322015760.180 Why?
Mitosis3201611810.180 Why?
Nerve Tissue Proteins2201144130.170 Why?
Protein Kinases3202416110.170 Why?
Muscle, Skeletal1201549780.170 Why?
Substrate Specificity9201517510.170 Why?
Mice322025820720.170 Why?
Cloning, Molecular6201541680.170 Why?
Class Ia Phosphatidylinositol 3-Kinase22017770.160 Why?
Homeostasis1201033470.160 Why?
NIH 3T3 Cells720196690.160 Why?
Dystrophin120002840.160 Why?
Genes, erbB-1220131630.160 Why?
Adenosine Triphosphatases120038420.160 Why?
Clathrin120202580.160 Why?
Receptors, Cell Surface8200428200.160 Why?
Salmonella typhimurium120013470.150 Why?
Adaptor Proteins, Vesicular Transport120203030.150 Why?
Ubiquitin-Protein Ligases4201019020.150 Why?
Pyrazoles3201620290.150 Why?
Foodborne Diseases12018410.150 Why?
Gene Expression6201776030.150 Why?
Serine Endopeptidases1200310270.150 Why?
Multiprotein Complexes2202211110.150 Why?
Food Analysis120181030.140 Why?
Salmonella120181250.140 Why?
Cytokinesis220101700.140 Why?
Static Electricity220122610.140 Why?
Birds220081660.140 Why?
Receptors, Mitogen22011610.140 Why?
Phosphatidylinositol 4,5-Diphosphate320141230.140 Why?
GTPase-Activating Proteins120204690.140 Why?
Fluorescence Polarization220211390.140 Why?
Cell Transformation, Neoplastic4202328480.140 Why?
Salmonella Infections120181720.140 Why?
Enzyme Inhibitors6201237260.130 Why?
Fluorobenzenes120181790.130 Why?
Acoustics120182440.130 Why?
Mutagenesis, Site-Directed5201716830.130 Why?
Eukaryotic Initiation Factors12016830.130 Why?
Molecular Conformation320175400.130 Why?
Shc Signaling Adaptor Proteins12015460.130 Why?
Hedgehog Proteins120217710.130 Why?
Escherichia coli9201542130.130 Why?
Antigens, CD7200440320.130 Why?
Adenocarcinoma5201464010.130 Why?
Receptors, Antigen, T-Cell2200325740.130 Why?
Recombinant Proteins6201565120.130 Why?
Benzamides2201413870.130 Why?
Cell Line102019156040.130 Why?
Drug Discovery2202110680.130 Why?
Lymphocyte Activation2200355050.120 Why?
Cell Membrane2202336590.120 Why?
Cell Division3202144780.120 Why?
Rabbits2201547740.120 Why?
Ligands3201932830.120 Why?
Dose-Response Relationship, Drug42024107650.120 Why?
Hydrogen Bonding520122900.120 Why?
Milk120184380.120 Why?
Drug Resistance, Multiple120162550.120 Why?
Drug Synergism2201617620.120 Why?
Calorimetry220061320.120 Why?
Recombinant Fusion Proteins5201237440.120 Why?
Amino Acid Substitution6201717420.120 Why?
Receptor, IGF Type 1120173840.120 Why?
Conserved Sequence3201611620.120 Why?
Quinolines320167720.120 Why?
Neurogenesis120218650.120 Why?
Crystallization220135200.110 Why?
Thermodynamics120155910.110 Why?
Cytoplasm3201015050.110 Why?
Publications120161950.110 Why?
Proteins5201660110.110 Why?
Neural Stem Cells120218950.110 Why?
Cerebellum1202115220.110 Why?
Biosensing Techniques220186620.110 Why?
Point Mutation6201115960.110 Why?
Autocrine Communication120141680.110 Why?
Cell Adhesion3201431020.110 Why?
T-Lymphocytes42004102760.100 Why?
Tandem Mass Spectrometry2201611970.100 Why?
Poly(ADP-ribose) Polymerases120144280.100 Why?
Binding, Competitive2201211420.100 Why?
Membrane Glycoproteins2200037130.100 Why?
Repressor Proteins1200329860.100 Why?
Receptor, Insulin119968380.100 Why?
Structural Homology, Protein22013860.100 Why?
Cell Polarity220076390.100 Why?
Resorcinols12012410.100 Why?
Protein Subunits320229430.100 Why?
Muscle Proteins1201711650.100 Why?
Models, Chemical320096110.100 Why?
Interferon Regulatory Factor-3120131460.100 Why?
Drosophila melanogaster2201117260.100 Why?
Cell Survival5201957930.100 Why?
I-kappa B Kinase120132500.100 Why?
Leukemia, B-Cell12012860.100 Why?
Aminopyridines120155800.090 Why?
DNA-Binding Proteins4201496180.090 Why?
rac GTP-Binding Proteins120111630.090 Why?
Schiff Bases12010220.090 Why?
Cyclic GMP120123940.090 Why?
Tropomyosin120111060.090 Why?
Mutation, Missense5201325920.090 Why?
Hypoxia-Inducible Factor 1, alpha Subunit320046270.090 Why?
Nuclear Magnetic Resonance, Biomolecular220035080.090 Why?
Peptide Library420163510.090 Why?
Isoxazoles120122330.090 Why?
Retroviridae220128490.090 Why?
Neoplasms, Muscle Tissue12010680.090 Why?
Benzimidazoles120158640.080 Why?
Tumor Necrosis Factor-alpha3199443560.080 Why?
Crystallography320051110.080 Why?
Lunate Bone12009380.080 Why?
Profilins22007650.080 Why?
Triangular Fibrocartilage12009270.080 Why?
Cell Physiological Phenomena120101520.080 Why?
Protein Biosynthesis1201620940.080 Why?
Proto-Oncogene Proteins c-fyn320041140.080 Why?
HSP90 Heat-Shock Proteins120124230.080 Why?
Databases, Genetic1201617580.080 Why?
Models, Anatomic120126830.080 Why?
Protein Folding220038710.080 Why?
Scaphoid Bone12009850.080 Why?
Xenograft Model Antitumor Assays4201936210.080 Why?
Genes, Reporter2200315240.080 Why?
Cell Cycle Proteins3201034500.070 Why?
BRCA1 Protein1201411560.070 Why?
Two-Hybrid System Techniques320044630.070 Why?
Gene Deletion1201526740.070 Why?
Cadherins220039060.070 Why?
Dexamethasone1201519650.070 Why?
Proteomics2202339140.070 Why?
Catalytic Domain120096990.070 Why?
Cell Movement3201252160.070 Why?
Membrane Proteins4201278850.070 Why?
Affinity Labels120071070.070 Why?
Integrins220208430.070 Why?
MicroRNAs1202338110.070 Why?
Mice, Knockout42025144840.070 Why?
Wrist Injuries120092150.070 Why?
Hydrophobic and Hydrophilic Interactions220103950.070 Why?
Leukemia1201515200.070 Why?
Circular Dichroism320033370.070 Why?
Bronchial Neoplasms120071110.070 Why?
Ligaments, Articular120093080.070 Why?
HeLa Cells3202030760.070 Why?
Proline220004550.070 Why?
Cell Nucleus2201628850.070 Why?
SH2 Domain-Containing Protein Tyrosine Phosphatases42001430.070 Why?
Precursor Cell Lymphoblastic Leukemia-Lymphoma1201515600.070 Why?
Lymphoma1201519000.060 Why?
Neuropeptides120119510.060 Why?
Peptide Fragments7201451510.060 Why?
Blood Proteins2200511910.060 Why?
Transduction, Genetic120089020.060 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 6420011210.060 Why?
Myeloproliferative Disorders120126160.060 Why?
Hydatidiform Mole, Invasive1200540.060 Why?
Glycine120086720.060 Why?
Immunoblotting3201316470.060 Why?
DNA Repair1201420540.060 Why?
Receptors, Immunologic2200314180.060 Why?
Isoindoles12024360.060 Why?
Oligopeptides1201011940.060 Why?
Repetitive Sequences, Amino Acid22001910.060 Why?
Proto-Oncogene Proteins c-cbl320001200.060 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11420012240.060 Why?
Codon220175990.060 Why?
Melanoma1202357090.060 Why?
Vaginal Neoplasms120051050.060 Why?
Transfection4201157630.060 Why?
Thrombocythemia, Essential120051140.060 Why?
Adipocytes, Brown120251600.060 Why?
Radius Fractures120095150.050 Why?
Mitochondrial Membranes120251850.050 Why?
X-Ray Diffraction320014170.050 Why?
Polycythemia Vera120051600.050 Why?
Purines120076150.050 Why?
Chickens120058450.050 Why?
Endopeptidase Clp12003420.050 Why?
HEK293 Cells3202042900.050 Why?
Sequence Analysis, Protein120042650.050 Why?
Qc-SNARE Proteins12003210.050 Why?
Qb-SNARE Proteins12003340.050 Why?
Phosphoserine120032040.050 Why?
Green Fluorescent Proteins1200820670.050 Why?
Primary Myelofibrosis120052090.050 Why?
Aminopeptidases120031140.050 Why?
Morphogenesis120077470.050 Why?
Phosphotransferases (Alcohol Group Acceptor)220144340.050 Why?
Gene Knockout Techniques220178080.050 Why?
Arthroscopy120099720.050 Why?
Insulin1201766100.050 Why?
Endocytosis120079590.050 Why?
Disease Models, Animal32017183540.050 Why?
Obesity12025130910.050 Why?
Transcription Factor 7-Like 1 Protein12001240.050 Why?
Asparagine120021200.050 Why?
Ciona intestinalis12021100.050 Why?
Epithelial Cells1201437020.050 Why?
Receptors, Aryl Hydrocarbon120042210.050 Why?
Kinetics2200863320.050 Why?
ZAP-70 Protein-Tyrosine Kinase21999690.050 Why?
Guanosine Triphosphate120223150.050 Why?
Magnetic Resonance Spectroscopy2202137820.050 Why?
Sulfolobus1200150.050 Why?
Dipeptides120033860.050 Why?
Azepines120033290.050 Why?
TCF Transcription Factors120011380.050 Why?
Gene Knockdown Techniques2201716080.050 Why?
Transcription Factor 7-Like 2 Protein120011530.050 Why?
Microtubules1200710620.050 Why?
EF Hand Motifs12000190.050 Why?
Dystroglycans12000620.040 Why?
Retroviridae Proteins, Oncogenic12000740.040 Why?
Amino Acids3201417160.040 Why?
Epitope Mapping120013000.040 Why?
Genes, ras120236650.040 Why?
Quinazolinones120222190.040 Why?
Thermogenesis120254940.040 Why?
Glioma1201535320.040 Why?
Molecular Chaperones120257630.040 Why?
Immunity, Innate1201230800.040 Why?
Breast Neoplasms32017211880.040 Why?