Harvard Catalyst Profiles

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Andrew James Aguirre, M.D., Ph.D.

Concepts (394)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Carcinoma, Pancreatic Ductal31202417564.090 Why?
Pancreatic Neoplasms46202454423.920 Why?
Proto-Oncogene Proteins p21(ras)24202417673.830 Why?
ras Proteins2202210581.010 Why?
Leucovorin220246430.980 Why?
Acetonitriles22024550.970 Why?
Intracellular Signaling Peptides and Proteins4202228920.820 Why?
Fluorouracil2202416520.790 Why?
Protein Phosphatase 1120221350.780 Why?
Oncogenes4202212340.770 Why?
Drug Resistance, Neoplasm9202453410.750 Why?
MAP Kinase Signaling System6202214950.750 Why?
Mutation282024302370.730 Why?
Deoxycytidine220248870.720 Why?
Endosomal Sorting Complexes Required for Transport120201490.660 Why?
Cell Line, Tumor332024171420.650 Why?
Vacuolar Proton-Translocating ATPases120201950.640 Why?
Paclitaxel3202417330.620 Why?
Pyrimidines5202430480.610 Why?
Cryoelectron Microscopy120226480.600 Why?
Adenocarcinoma14202463950.590 Why?
Neoplasms212024223710.580 Why?
Genomics8202459260.580 Why?
Antineoplastic Agents132024136770.570 Why?
Guanosine Triphosphate520243150.570 Why?
Gene Expression Profiling12202495400.540 Why?
Multiprotein Complexes1202211100.510 Why?
Antineoplastic Combined Chemotherapy Protocols82024118780.510 Why?
Gene Expression Regulation, Neoplastic19202486480.500 Why?
Piperazines3202425540.490 Why?
Mitogen-Activated Protein Kinases1201912460.470 Why?
Gene Dosage4201612190.450 Why?
Colorectal Neoplasms7202469750.440 Why?
Gene Targeting220168410.420 Why?
Iron-Sulfur Proteins22022840.400 Why?
Tumor Microenvironment9202339480.380 Why?
Genes, ras420246630.380 Why?
Appendiceal Neoplasms220231550.350 Why?
Protein Kinase Inhibitors9202357040.330 Why?
Stomach Neoplasms3202414810.320 Why?
Lung Neoplasms102024135860.320 Why?
Xenograft Model Antitumor Assays8202436120.310 Why?
Signal Transduction122024236480.300 Why?
Tumor Suppressor Protein p14ARF32006840.300 Why?
Genetic Association Studies1201727440.300 Why?
Cell Proliferation132024104780.290 Why?
Humans9120247681710.280 Why?
Albumins320245770.280 Why?
Cyclin-Dependent Kinase Inhibitor p16320067100.270 Why?
Animals4120241692850.260 Why?
Tumor Suppressor Protein p535202029560.260 Why?
Mice322024820490.260 Why?
Proto-Oncogene Proteins3202345280.250 Why?
Carcinoma, Non-Small-Cell Lung3202154320.230 Why?
HCT116 Cells320214050.230 Why?
raf Kinases220221170.230 Why?
Benzimidazoles220218640.230 Why?
Oncogene Protein p21(ras)12024690.230 Why?
Class I Phosphatidylinositol 3-Kinases220199050.220 Why?
DNA Copy Number Variations3202420480.220 Why?
Gene Knockout Techniques220178060.220 Why?
Genetic Predisposition to Disease62020180650.220 Why?
Protein Stability220225790.210 Why?
Genetic Variation1201866100.210 Why?
Haptens120221630.200 Why?
Pyridines3202428940.200 Why?
Single-Cell Analysis4202125400.200 Why?
Hypoalbuminemia12023900.200 Why?
DNA Repair3202120500.190 Why?
Receptor, IGF Type 1220233840.190 Why?
Crk-Associated Substrate Protein12021390.190 Why?
Gene Regulatory Networks3202117520.190 Why?
GTP Phosphohydrolases220245250.190 Why?
Neoplasm Proteins4201836040.190 Why?
Nissl Bodies12020160.180 Why?
Nerve Tissue12021780.180 Why?
Ameloblastoma12021420.180 Why?
src-Family Kinases220215390.180 Why?
Protein-Arginine N-Methyltransferases120211290.180 Why?
Jaw Neoplasms12021710.180 Why?
Smad4 Protein120211930.170 Why?
Mice, Hairless12019390.170 Why?
DNA-Directed DNA Polymerase120234810.170 Why?
Amino Acid Motifs120229300.170 Why?
Pinocytosis12019630.170 Why?
Neoplasms, Experimental3202012300.160 Why?
Codon120215990.160 Why?
Myeloid Cells220218390.160 Why?
Proto-Oncogene Proteins c-fos120215800.160 Why?
Extracellular Signal-Regulated MAP Kinases120216150.160 Why?
Neuregulin-1120191360.150 Why?
MAP Kinase Kinase Kinase 112018560.150 Why?
Cell-Penetrating Peptides12018440.150 Why?
Organoids320217430.150 Why?
Fusobacterium12017560.150 Why?
Mice, SCID2201926270.140 Why?
Molecular Targeted Therapy3202428300.140 Why?
Ketoglutarate Dehydrogenase Complex12017210.140 Why?
Enteric Nervous System120202130.140 Why?
Neurosciences120223830.140 Why?
Anilides120204130.140 Why?
Receptor, erbB-22202426030.140 Why?
Colonic Polyps120215570.140 Why?
Gene Amplification2202410950.140 Why?
Peritoneal Neoplasms120237140.130 Why?
Kaplan-Meier Estimate2202465250.130 Why?
Lipid Peroxidation120172760.130 Why?
Neoplasm Metastasis2202449130.130 Why?
Protein Conformation2202139560.130 Why?
Metronidazole120172360.130 Why?
Cyclin-Dependent Kinases120196630.130 Why?
Membrane Proteins3202478760.130 Why?
Glutathione Peroxidase120172590.130 Why?
DNA Cleavage12016560.130 Why?
Proto-Oncogene Proteins B-raf2202320590.130 Why?
p21-Activated Kinases220231270.130 Why?
Proto-Oncogene Proteins c-myc120219980.130 Why?
RNA Splicing120209050.130 Why?
Microtubules1202110640.120 Why?
Genomic Instability120197160.120 Why?
Prognosis72024300090.120 Why?
Gastrointestinal Neoplasms120239570.120 Why?
Cysteine120208970.120 Why?
Genes, Essential120161850.120 Why?
Antigens, Protozoan120173150.120 Why?
Small Cell Lung Carcinoma120194540.120 Why?
Phosphorylation2202383160.120 Why?
Mutagenesis1201812280.120 Why?
Protein-Tyrosine Kinases1202324330.120 Why?
Inservice Training120163750.110 Why?
Esophageal Neoplasms1202416680.110 Why?
Body Composition1202324620.110 Why?
Diabetes Complications1202013200.110 Why?
Binding Sites1202260190.110 Why?
Sequence Analysis, RNA2201820400.110 Why?
DNA Damage3202024690.110 Why?
Aged1320241715020.110 Why?
Protein Binding2202293430.100 Why?
Tumor Cells, Cultured4202061240.100 Why?
Unnecessary Procedures120164120.100 Why?
Mutation, Missense1202225920.100 Why?
Germ-Line Mutation2201818850.100 Why?
Apoptosis4202495270.100 Why?
Oligopeptides1201811940.100 Why?
Drug Screening Assays, Antitumor320207190.100 Why?
Male2420243647310.100 Why?
Chromosome Mapping2202246200.100 Why?
Nuclear Receptor Coactivators22022620.100 Why?
Sulfur220221580.100 Why?
Biological Availability220223910.100 Why?
Proteomics3202039120.100 Why?
RNA, Small Interfering2201834280.100 Why?
Middle Aged1320242234870.090 Why?
Transcription Factors52022121710.090 Why?
Genome, Human3201644460.090 Why?
Clinical Laboratory Techniques120167470.090 Why?
Female2520243971870.090 Why?
Mice, Nude4202136230.090 Why?
High-Throughput Screening Assays120169420.090 Why?
Structure-Activity Relationship3202030560.090 Why?
Genome3202317540.080 Why?
Gene Expression Regulation, Developmental1202036100.080 Why?
Carcinoma, Squamous Cell2202440580.080 Why?
Cell Transformation, Neoplastic2201728460.080 Why?
Mice, Inbred C57BL62024223800.080 Why?
Weight Loss1202027210.080 Why?
Nucleic Acid Hybridization3200513050.080 Why?
Gene Expression2201676010.080 Why?
Neoplasm Recurrence, Local3202494190.080 Why?
Colonic Neoplasms1202025410.080 Why?
Iron3202218130.070 Why?
Oligonucleotide Array Sequence Analysis3200538060.070 Why?
Neoadjuvant Therapy3202429070.070 Why?
rho GTP-Binding Proteins120082790.070 Why?
Computational Biology3202135670.070 Why?
Pancreatic Ducts120083300.070 Why?
Nanoparticles1201819860.070 Why?
Energy Metabolism1201729070.070 Why?
Enzyme Inhibitors1201737280.070 Why?
Pyrimidinones220203860.070 Why?
Academic Medical Centers1201627850.060 Why?
Repressor Proteins1201729820.060 Why?
Molecular Structure2202018840.060 Why?
Nuclear Proteins3202158040.060 Why?
Pancreas2202416990.060 Why?
Adult920242236460.060 Why?
RNA, Messenger12020128010.060 Why?
Stromal Cells2202113370.060 Why?
Multiple Myeloma1202351960.060 Why?
Mice, Inbred BALB C2202462310.060 Why?
Pancreatectomy220208250.060 Why?
Cell Death2202116800.060 Why?
CA-19-9 Antigen120241090.060 Why?
Genes, p53120067140.050 Why?
Transforming Growth Factors12023760.050 Why?
Down-Regulation2202129390.050 Why?
Pyridones220208190.050 Why?
Respiration1199016650.050 Why?
Homozygote2200617790.050 Why?
Focal Adhesion Protein-Tyrosine Kinases120231830.050 Why?
Genes, myc120243910.050 Why?
Chromosomes, Human, Pair 17120044180.050 Why?
rhoA GTP-Binding Protein120232350.050 Why?
Gene Deletion3200626740.050 Why?
Claudins120231160.050 Why?
Esophagogastric Junction120243510.050 Why?
Colon2202018010.050 Why?
Cachexia120232020.050 Why?
High-Throughput Nucleotide Sequencing3201836700.050 Why?
Nervous System Physiological Phenomena120221140.050 Why?
Integrases120035200.050 Why?
DNA, Neoplasm2202317440.050 Why?
Chromosomes120045780.050 Why?
Genes, p16120011590.050 Why?
Alleles3201868940.050 Why?
Spliceosomes120211160.050 Why?
Neurons1202095140.050 Why?
Fibroblasts3201441780.050 Why?
Endoplasmic Reticulum, Rough12020210.050 Why?
Cell Compartmentation120213830.040 Why?
Calpain120211460.040 Why?
Polymorphism, Single Nucleotide22020160440.040 Why?
Muscular Atrophy120233350.040 Why?
Micronucleus Tests12019230.040 Why?
Half-Life120216510.040 Why?
Mitogen-Activated Protein Kinase Kinases120236370.040 Why?
Mice, Knockout42020144880.040 Why?
Chemokine CXCL9120191350.040 Why?
DNA Mutational Analysis2201841200.040 Why?
Ubiquitin Thiolesterase120234650.040 Why?
Aged, 80 and over32021596260.040 Why?
Mice, Transgenic2202095610.040 Why?
Acetamides120212590.040 Why?
Ferritins120226010.040 Why?
Biomarkers, Pharmacological120201620.040 Why?
Disease-Free Survival2202068470.040 Why?
Edema120237650.040 Why?
Anti-Bacterial Agents1201774770.040 Why?
Treatment Outcome52024653790.040 Why?
HEK293 Cells2202142800.040 Why?
Cohort Studies42023417530.040 Why?
Microscopy, Electron, Transmission120206870.040 Why?
Methylation1202110780.040 Why?
DNA-Binding Proteins2201496170.040 Why?
Hydrolysis120196460.040 Why?
DNA Mismatch Repair120214310.040 Why?
Heart Rate1199042140.040 Why?
Poly(ADP-ribose) Polymerases120204280.040 Why?
Circadian Clocks120201680.040 Why?
Genetic Heterogeneity120217360.040 Why?
Morpholines120215840.040 Why?
Ileum120205580.040 Why?
Molecular Diagnostic Techniques120236200.040 Why?
Neoplasm Invasiveness2202136200.040 Why?
Prevotella12017810.040 Why?
Chromosome Aberrations1200417780.040 Why?
CD8-Positive T-Lymphocytes2202346480.040 Why?
Tubulin120216950.040 Why?
HT29 Cells120171890.040 Why?
Lipid Peroxides12017740.040 Why?
Transcription, Genetic2202176090.040 Why?
Bacteroides120171650.040 Why?
Ribosomes120204970.030 Why?
Drug Synergism1202117600.030 Why?
Chemokines120219630.030 Why?
Catalytic Domain120196990.030 Why?
Phenotype32023167260.030 Why?
Cytoplasm1202115050.030 Why?
Adaptive Immunity120217330.030 Why?
NIH 3T3 Cells120186690.030 Why?
Genome-Wide Association Study12016127950.030 Why?
Electrocardiography1199064120.030 Why?
Inflammation32021108730.030 Why?
Ion Channels1202110430.030 Why?
Viral Proteins1200318020.030 Why?
Genes, BRCA1120207550.030 Why?
Survival Analysis22020100990.030 Why?
Databases, Genetic2201817580.030 Why?
Cell Transdifferentiation120171860.030 Why?
Actins1202320640.030 Why?
Bone Morphogenetic Proteins120218460.030 Why?
Citric Acid Cycle120172340.030 Why?
Intestinal Diseases120205050.030 Why?
Cells, Cultured32020190250.030 Why?
Liver Neoplasms2202443630.030 Why?
Immunity1202110030.030 Why?
Transforming Growth Factor beta1202320040.030 Why?
Mice, Inbred NOD1201918370.030 Why?
Drug Design1202010460.030 Why?
Enhancer Elements, Genetic1202113670.030 Why?
Neuroglia120209600.030 Why?
Protein Isoforms1201917150.030 Why?
Autophagy1202213510.030 Why?
Immune System120198000.030 Why?
Disease Models, Animal32024183490.030 Why?
Genes, Neoplasm120163710.030 Why?
Mesoderm120176790.030 Why?
Organizational Policy120164350.030 Why?
Standard of Care120185680.030 Why?
Neoplastic Stem Cells1202113510.030 Why?
DNA Breaks, Double-Stranded120186060.030 Why?
Pyrroles1201911240.030 Why?
Protein Processing, Post-Translational1202119660.030 Why?
Cell Movement2202052130.030 Why?
ROC Curve1202136280.030 Why?
Glycolysis120178370.030 Why?
RNA1202327220.030 Why?
Models, Biological2202094970.030 Why?
Patient Care Team1202425230.030 Why?
Vascular Endothelial Growth Factor A1200335170.030 Why?
Polyethylene Glycols1201811970.030 Why?
Cadherins120179050.030 Why?
Epithelial-Mesenchymal Transition120177570.020 Why?
Combined Modality Therapy1202485420.020 Why?
Monocytes1202126050.020 Why?
False Positive Reactions120149630.020 Why?
Reproducibility of Results22021202250.020 Why?
Interferon-gamma1201931610.020 Why?
Adipose Tissue1202333340.020 Why?
Medical Order Entry Systems120165240.020 Why?
Adenoma1202121590.020 Why?
Up-Regulation1202041490.020 Why?
Histones1202126010.020 Why?
Medical Oncology1202323460.020 Why?
Cell Survival1202057890.020 Why?
Proteome1202018900.020 Why?
Nervous System Diseases1202016620.020 Why?
DNA Methylation1202444280.020 Why?
Base Sequence12020124220.020 Why?
Peptides1202143540.020 Why?
Models, Molecular1201954020.020 Why?
Pyrazoles1201920280.020 Why?
Palliative Care1202436430.020 Why?
Disease Progression22021136680.020 Why?
Neutrophils1202137860.020 Why?
Endothelial Cells1202135890.020 Why?
Zebrafish1202030350.020 Why?
Tumor Necrosis Factor-alpha1201943550.020 Why?
Epithelial Cells1202037030.020 Why?
Intestinal Mucosa1201930440.020 Why?
Cell Lineage1201725750.020 Why?
Homeostasis1201933480.020 Why?
Muscle, Skeletal1202349780.020 Why?
Amino Acid Sequence12020134220.020 Why?
Gene Silencing1201415050.020 Why?
Cell Line, Transformed120088660.020 Why?
Sequence Analysis, DNA1201847860.020 Why?
CD4-Positive T-Lymphocytes1201944150.020 Why?
T-Lymphocytes22021102660.020 Why?
Proteins1200160090.020 Why?
Proportional Hazards Models12021125430.020 Why?
Immunotherapy1202247540.020 Why?
Clinical Trials as Topic1202280520.020 Why?
Models, Statistical1202051070.020 Why?
Time Factors22020402200.020 Why?
Cell Nucleus1201428850.020 Why?
Cytogenetics120051980.010 Why?
Immunohistochemistry12018110950.010 Why?
Cell Differentiation12021116770.010 Why?
Rats12020237820.010 Why?
Chromosomes, Human, Pair 3120053230.010 Why?
Boston1201693740.010 Why?
Retrospective Studies22023817600.010 Why?
Body Mass Index12020130530.010 Why?
Quality of Life12024134900.010 Why?
Incidence12020215380.010 Why?
Gene Expression Regulation12020119300.010 Why?
Chromatin1201429810.010 Why?
Urethane12001380.010 Why?
9,10-Dimethyl-1,2-benzanthracene12001580.010 Why?
Aging1202087430.010 Why?
Genes, Tumor Suppressor1200510620.010 Why?
Histone-Lysine N-Methyltransferase120057010.010 Why?
Microtubule-Associated Proteins1200510740.010 Why?
Proto-Oncogene Proteins c-akt1200824590.010 Why?
Cell Line12014156020.010 Why?
Carcinogens120014530.010 Why?
In Situ Hybridization, Fluorescence1200525210.010 Why?
Melanoma1201757060.010 Why?
Heart1199044460.010 Why?
Follow-Up Studies12018393540.010 Why?
Thymus Gland1200112660.010 Why?
Phosphoproteins1200524510.010 Why?
Trans-Activators1200528570.010 Why?
Embryo, Mammalian1200116760.010 Why?
Tumor Suppressor Proteins1200528100.010 Why?
Polymerase Chain Reaction1200460820.010 Why?
Prostatic Neoplasms12017111010.010 Why?
Cell Division1200144770.010 Why?
Cell Cycle Proteins1200534450.010 Why?
Prospective Studies12018549240.010 Why?
Carrier Proteins1200549390.010 Why?
Child11990809170.000 Why?
Adolescent11990891690.000 Why?
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Concepts (394)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.