Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Sirano Dhe-Paganon, Ph.D.

Concepts (472)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Structure, Tertiary34201542131.790 Why?
Models, Molecular44202056601.620 Why?
Crystallography, X-Ray34202020451.380 Why?
Ubiquitin-Protein Ligases12201516721.110 Why?
Ubiquitin920178381.070 Why?
CCAAT-Enhancer-Binding Proteins420152881.010 Why?
Dipeptidyl-Peptidases and Tripeptidyl-Peptidases42015700.890 Why?
Catalytic Domain1220207380.880 Why?
Ubiquitin-Conjugating Enzymes620132050.820 Why?
Endopeptidases420138140.780 Why?
Receptor Protein-Tyrosine Kinases4201315460.740 Why?
Peptidylprolyl Isomerase220101940.720 Why?
Amino Acid Sequence332021145680.720 Why?
Protein Structure, Secondary14201312770.710 Why?
Protein Binding30202198250.700 Why?
Ubiquitin-Activating Enzymes32014660.670 Why?
Adenosine Triphosphate5201821570.640 Why?
Binding Sites19202064160.630 Why?
Molecular Sequence Data302013194320.610 Why?
Phosphotransferases (Alcohol Group Acceptor)420203930.560 Why?
Protein Conformation18202041090.540 Why?
Lysosome-Associated Membrane Glycoproteins120131130.540 Why?
Cyclophilins22010500.540 Why?
Carbon-Nitrogen Lyases1201280.500 Why?
Dipeptidyl Peptidase 4120121080.500 Why?
Nuclear Proteins9201859160.490 Why?
Sequence Homology, Amino Acid14201230210.490 Why?
Zinc Compounds12012420.490 Why?
Fluorides120121270.470 Why?
Proto-Oncogene Proteins6202046340.450 Why?
Receptor, EphA112010200.440 Why?
Proline120124380.440 Why?
Ubiquitination720209500.440 Why?
Ubiquitin Thiolesterase420174150.430 Why?
Biocatalysis220121900.420 Why?
Chromatography, Affinity120115910.420 Why?
Calpain220091550.410 Why?
Ephrins12009340.410 Why?
Transcription Factors112020117200.400 Why?
Enzyme Inhibitors8202139610.400 Why?
Protein Multimerization5201510110.390 Why?
Protein Folding420118770.390 Why?
Histones3202025490.390 Why?
Heterochromatin120112940.380 Why?
Protease Inhibitors320208330.380 Why?
Models, Chemical320096880.360 Why?
Caspases120119500.360 Why?
Receptors, Purinergic P2X722018940.360 Why?
Small Molecule Libraries720207110.360 Why?
Drug Design7202011340.360 Why?
Structure-Activity Relationship13202132740.350 Why?
Nuclear Magnetic Resonance, Biomolecular620165670.350 Why?
Thiosulfate Sulfurtransferase1200690.350 Why?
Sequence Alignment8201323540.350 Why?
Leukemia4201714110.340 Why?
Recombinant Fusion Proteins5201539450.340 Why?
AMP-Activated Protein Kinases120105070.330 Why?
Substrate Specificity7201719600.330 Why?
Ligands8201830960.320 Why?
Multigene Family1201011880.320 Why?
Adenosine Triphosphatases220158910.320 Why?
Protein Interaction Domains and Motifs420175280.320 Why?
Catalysis420139190.310 Why?
Dimerization520129360.310 Why?
Neoplasm Proteins3202038010.310 Why?
DNA-Binding Proteins10201797760.300 Why?
Antineoplastic Agents102021135980.300 Why?
Ubiquitins320204160.300 Why?
Oligopeptides4202013030.300 Why?
Cell Cycle Proteins4202032790.300 Why?
Microfluidic Analytical Techniques120117360.290 Why?
Nucleosomes320204680.290 Why?
Chromosomal Proteins, Non-Histone220207060.280 Why?
Phosphoproteins5200326260.280 Why?
Multiprotein Complexes5201311570.270 Why?
Azepines220163420.270 Why?
DNA6201573210.260 Why?
CpG Islands3201511010.260 Why?
Tumor Suppressor Protein p534202028660.260 Why?
Phenylalanine120043760.250 Why?
Thiophenes220175900.250 Why?
Adaptor Proteins, Vesicular Transport120043150.250 Why?
Phosphotyrosine420134630.250 Why?
DNA Methylation3201537970.240 Why?
Protein Kinase Inhibitors4202049350.240 Why?
Molecular Structure8202120310.240 Why?
Proto-Oncogene Proteins c-bcl-22202013690.240 Why?
Protein Structure, Quaternary520124780.240 Why?
Hydrogen Bonding320113050.230 Why?
Gene Expression Regulation, Neoplastic6202084710.230 Why?
Protein Kinase C1200613180.220 Why?
Humans8320216607310.220 Why?
CHO Cells3201314440.220 Why?
Molecular Conformation420115970.220 Why?
HEK293 Cells10202141690.220 Why?
Iron-Binding Proteins12000910.220 Why?
Tacrolimus Binding Proteins220131800.210 Why?
Thiazolidines12020840.210 Why?
Mutation132021278320.210 Why?
Peptides4202144890.210 Why?
Urea Cycle Disorders, Inborn12020300.210 Why?
Minor Histocompatibility Antigens220203090.210 Why?
Axonal Transport120211940.210 Why?
Cell Line, Tumor162020165390.210 Why?
Adaptor Proteins, Signal Transducing3200926600.200 Why?
STAT5 Transcription Factor220192920.200 Why?
Proteins3201061880.200 Why?
Cell Proliferation112021108110.200 Why?
Saccharomyces cerevisiae Proteins1200920260.200 Why?
Leukemia, T-Cell120191150.200 Why?
Static Electricity220122740.190 Why?
Sarcoma, Synovial120201720.190 Why?
Genes, Essential120201810.190 Why?
Serpins120202830.190 Why?
Peptide Hydrolases220156670.190 Why?
Repressor Proteins3202029700.190 Why?
Recombinant Proteins7201770240.190 Why?
Cyclin-Dependent Kinase Inhibitor p16220127070.190 Why?
Apoproteins12017570.190 Why?
Cysteine Endopeptidases220146820.180 Why?
Urea120204420.180 Why?
Disulfides120204600.180 Why?
Kinesin120213520.180 Why?
Saccharomyces cerevisiae1200928990.180 Why?
Loss of Heterozygosity120207030.180 Why?
Arginine120208730.160 Why?
Phosphorylation9202187910.160 Why?
Lymphoma, T-Cell120193080.160 Why?
2-Aminopurine12015150.160 Why?
Transcriptional Elongation Factors120171490.160 Why?
Cytotoxicity, Immunologic1202015780.160 Why?
Amino Acids2201216710.160 Why?
Phthalimides12015170.160 Why?
Animals2820211685010.160 Why?
Tretinoin120185140.150 Why?
Proto-Oncogene Proteins c-myc120219940.150 Why?
Chromatin Assembly and Disassembly120196020.150 Why?
Evolution, Molecular3201619840.150 Why?
Mass Spectrometry2201422630.150 Why?
Apoptosis72021102320.150 Why?
Mevalonic Acid11994410.150 Why?
Cloning, Molecular4201746800.140 Why?
Carboxy-Lyases11994940.140 Why?
Fatty Acids1200216290.140 Why?
Fluorescence Recovery After Photobleaching12014580.140 Why?
Cyclopentanes12014930.140 Why?
Mutagenesis, Site-Directed3201118520.140 Why?
Escherichia coli6201744050.140 Why?
fms-Like Tyrosine Kinase 3120174560.130 Why?
Protein-Serine-Threonine Kinases2201739180.130 Why?
Proto-Oncogene Proteins c-mdm2220203790.130 Why?
Publications120161860.130 Why?
Macromolecular Substances1201615400.130 Why?
Pyrimidines2201626740.130 Why?
High-Throughput Screening Assays220209110.130 Why?
Histidine220113380.130 Why?
Protein Processing, Post-Translational3201120850.130 Why?
Magnetic Resonance Spectroscopy4201836710.130 Why?
Catechin12012730.130 Why?
Carrier Proteins4201852430.130 Why?
Proteomics3201828580.130 Why?
Th2 Cells1201810390.130 Why?
Tandem Mass Spectrometry2201610930.120 Why?
Opioid Peptides12012380.120 Why?
Combinatorial Chemistry Techniques120131450.120 Why?
Axons1202116720.120 Why?
Immediate-Early Proteins120155030.120 Why?
Herpes Simplex120154680.120 Why?
Oncogene Proteins, Fusion1202014100.120 Why?
Methyltransferases120153330.120 Why?
Ubiquitinated Proteins12011310.120 Why?
Insulin-Secreting Cells120209470.120 Why?
Th17 Cells120186750.120 Why?
Leukemia, Myeloid, Acute4202028530.120 Why?
Cricetulus120138480.120 Why?
Quinolines120166990.120 Why?
Transformation, Bacterial12011880.120 Why?
Entropy120122080.110 Why?
Cysteine220208360.110 Why?
Potassium Channels, Voltage-Gated120121330.110 Why?
Ryanodine Receptor Calcium Release Channel120121930.110 Why?
Centrifugation120111320.110 Why?
Mice152021791080.110 Why?
Peptide Fragments2201751120.110 Why?
HeLa Cells2201933390.110 Why?
Intracellular Signaling Peptides and Proteins3201729200.110 Why?
src Homology Domains520193570.110 Why?
Ephrin-A512010160.110 Why?
Ephrin-A112010100.110 Why?
Blotting, Western4201757510.110 Why?
Kinetics5201369940.110 Why?
RNA1202124470.110 Why?
Crystallization220125400.110 Why?
Signal Transduction72018238440.110 Why?
DNA Replication2201514660.110 Why?
Cell Survival5202162840.110 Why?
Receptor, EphA212010430.110 Why?
Triazoles120169180.110 Why?
Ubiquitin-Protein Ligase Complexes120111700.110 Why?
Ligases120123650.110 Why?
Sulfonamides1202017800.110 Why?
Receptor, EphA31200970.110 Why?
Cricetinae2201226400.100 Why?
Crystallography220071100.100 Why?
Thalidomide120158710.100 Why?
Silicon Dioxide120112410.100 Why?
Drug Screening Assays, Antitumor320217500.100 Why?
Fluorescence Polarization120091270.100 Why?
Herpesvirus 1, Human120157400.100 Why?
src-Family Kinases120135750.100 Why?
Receptors, Eph Family12009510.100 Why?
Dose-Response Relationship, Drug62021115840.100 Why?
Retinal Pigment Epithelium120132980.100 Why?
Databases, Genetic1201616940.100 Why?
Surface Properties1201212100.100 Why?
Eye Proteins120137210.090 Why?
Biphenyl Compounds120113710.090 Why?
Chemical Fractionation12008640.090 Why?
Chemistry, Physical120081720.090 Why?
Proteasome Endopeptidase Complex2201814640.090 Why?
Enzyme Activation6201439460.090 Why?
Immunoglobulins120118870.090 Why?
Neoplasms, Experimental3202114140.090 Why?
Chemistry, Pharmaceutical120092930.090 Why?
Glucose1202039310.090 Why?
Peptide Library120093350.090 Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization120105390.090 Why?
Drug Evaluation, Preclinical1201414550.090 Why?
5-Methylcytosine120081580.090 Why?
Neoplasms32020184760.090 Why?
Genes, Tumor Suppressor1201211060.090 Why?
Pyridines1202027240.090 Why?
Spliceosomes120081580.090 Why?
Phagocytosis2201315450.080 Why?
Plasmids2201125030.080 Why?
Multiple Myeloma2201745530.080 Why?
Zinc120117170.080 Why?
Lipase120082950.080 Why?
Histone Deacetylases120117260.080 Why?
Pyrazoles1201616940.080 Why?
DNA Mutational Analysis3201443320.080 Why?
Drug Discovery3202010190.080 Why?
Spectrum Analysis, Raman120082320.080 Why?
Cell Line52015169520.080 Why?
Heart Transplantation1201828330.080 Why?
Endosomal Sorting Complexes Required for Transport120061410.080 Why?
Immunotherapy1202033690.080 Why?
Fluorescent Dyes1201419400.080 Why?
Tyrosine2200815070.080 Why?
DNA Repair1201519390.080 Why?
Gene Knockdown Techniques3201717020.080 Why?
Protein Subunits1201010460.080 Why?
Leukemia, Promyelocytic, Acute220182410.080 Why?
Genetic Vectors2201736010.080 Why?
CD8-Positive T-Lymphocytes1201838520.070 Why?
Graft Rejection1201842110.070 Why?
Epinephrine120087980.070 Why?
Reactive Oxygen Species1201220620.070 Why?
Solutions220164430.070 Why?
Diabetes Mellitus, Type 11201831270.070 Why?
Amino Acid Motifs220219860.070 Why?
Phylogeny1201227770.070 Why?
Protein Engineering120085720.070 Why?
Protein Kinases2201616640.070 Why?
Transcription, Genetic2201780860.060 Why?
Mice, Inbred NOD2201819120.060 Why?
Immune System120087880.060 Why?
Annelida1200260.060 Why?
Membrane Proteins1202081070.060 Why?
Lamins12002370.060 Why?
Gene Expression Regulation22013124830.060 Why?
Anura120021010.060 Why?
Hepatocyte Nuclear Factor 4120021160.060 Why?
Diptera12002560.060 Why?
Water1200812270.060 Why?
Base Sequence22012137410.060 Why?
Histone-Lysine N-Methyltransferase220176410.060 Why?
Lamin Type A120021490.060 Why?
Tumor Suppressor Proteins1201228810.060 Why?
Lipodystrophy120021360.060 Why?
Pyruvate Carboxylase12020110.060 Why?
Molecular Targeted Therapy3202027310.060 Why?
Conserved Sequence2201612710.060 Why?
Tumor Cells, Cultured2202167410.050 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors120022720.050 Why?
Friedreich Ataxia12000630.050 Why?
Inflammation1202091630.050 Why?
Epigenesis, Genetic2201731840.050 Why?
Mutagenesis2201813030.050 Why?
Precursor Cell Lymphoblastic Leukemia-Lymphoma2202013480.050 Why?
Nerve Tissue Proteins2201146770.050 Why?
Mice, Knockout22018153400.050 Why?
DNA Primase120201300.050 Why?
Insulin Receptor Substrate Proteins219995820.050 Why?
Granzymes120202640.050 Why?
Phosphatidylinositol 4,5-Diphosphate119991140.050 Why?
Citric Acid Cycle120202110.050 Why?
Muscular Dystrophies120024410.050 Why?
Glycosylation2201511100.050 Why?
Models, Biological32013101710.050 Why?
Fishes120025690.050 Why?
Drug Resistance, Neoplasm1201449740.050 Why?
Mice, Inbred BALB C2201867540.050 Why?
NIH 3T3 Cells120207160.050 Why?
Ganglia, Spinal120215270.050 Why?
Tryptophan120204440.050 Why?
Receptors, Cytoplasmic and Nuclear120028430.040 Why?
Aspartic Acid120205930.040 Why?
Cytoplasmic Granules120216920.040 Why?
Mutant Proteins120195240.040 Why?
Rats42013254240.040 Why?
Lipids1200830490.040 Why?
Homeostasis1200832350.040 Why?
Hydrophobic and Hydrophilic Interactions120174430.040 Why?
Sensory Receptor Cells120214440.040 Why?
3T3 Cells1201811470.040 Why?
Shal Potassium Channels12015230.040 Why?
Thrombosis1200826400.040 Why?
Tacrolimus Binding Protein 1A12015450.040 Why?
Protein Interaction Mapping220116540.040 Why?
Protein Tyrosine Phosphatases119984990.040 Why?
Immunity120207930.040 Why?
Myeloid-Lymphoid Leukemia Protein120172730.040 Why?
Stromal Cells1202013440.040 Why?
Amino Acid Substitution1202018960.040 Why?
Proliferating Cell Nuclear Antigen120152970.040 Why?
Breast Neoplasms22020188530.040 Why?
Gene Knockout Techniques120177630.040 Why?
Molecular Dynamics Simulation120163540.040 Why?
Protein Isoforms2201217190.030 Why?
U937 Cells120142740.030 Why?
Neoplasm Transplantation1201823000.030 Why?
S-Adenosylmethionine120152030.030 Why?
Rod Cell Outer Segment12013660.030 Why?
Protein Stability120155420.030 Why?
GRB2 Adaptor Protein12013990.030 Why?
RNA Polymerase II120175010.030 Why?
Cullin Proteins120141770.030 Why?
Calmodulin120132180.030 Why?
Proto-Oncogene Proteins c-vav12013980.030 Why?
Proto-Oncogene Proteins p21(ras)1202015300.030 Why?
Class Ia Phosphatidylinositol 3-Kinase12013590.030 Why?
Enhancer Elements, Genetic1201913410.030 Why?
Heterozygote1201927410.030 Why?
Calorimetry120121280.030 Why?
K562 Cells120146580.030 Why?
Lymphocyte Activation2201859090.030 Why?
Computer Simulation1200660960.030 Why?
Metabolomics1202011750.030 Why?
Gene Deletion1202028790.030 Why?
Receptor, Insulin119968470.030 Why?
Mice, Inbred C57BL22021228920.030 Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2120121820.030 Why?
Methylation1201511110.030 Why?
Iron1200017060.030 Why?
RING Finger Domains1201050.030 Why?
Allosteric Site120111080.030 Why?
Phenylurea Compounds120155360.030 Why?
Triticum12011990.030 Why?
Protein Denaturation120112580.030 Why?
Jurkat Cells120128190.030 Why?
Molecular Weight1201325290.030 Why?
Choroid120133310.030 Why?
Nitric Oxide1202021690.030 Why?
RNA-Binding Proteins1202018640.030 Why?
Tumor Microenvironment1202020330.030 Why?
Autoimmunity1201812530.030 Why?
Cyclin D312010540.030 Why?
Carcinoma, Pancreatic Ductal1202012920.030 Why?
Hematopoietic System120101150.030 Why?
Pyrroles1201711970.030 Why?
Zinc Fingers120126480.030 Why?
Adenosine120157940.030 Why?
Trypsin120105490.030 Why?
Cryoelectron Microscopy120124630.030 Why?
Paraoxon1200810.020 Why?
Electrophoresis, Polyacrylamide Gel1201220110.020 Why?
Cell Transformation, Neoplastic1202030200.020 Why?
Models, Genetic1202035520.020 Why?
Immunophilins12008220.020 Why?
Rats, Sprague-Dawley1202187450.020 Why?
Chickens120118810.020 Why?
Surface Plasmon Resonance120092820.020 Why?
Hematologic Neoplasms1201915020.020 Why?
Genome1201716410.020 Why?
Alleles1202069490.020 Why?
Thiolester Hydrolases120091010.020 Why?
Female720203651990.020 Why?
Point Mutation1201416980.020 Why?
Yeasts120092980.020 Why?
Insulin1200363690.020 Why?
RNA, Small Interfering1201837190.020 Why?
Cytosol120119220.020 Why?
Lysine1201210220.020 Why?
Culture Media120099820.020 Why?
Immunologic Factors1201714040.020 Why?
Mitochondria1202134550.020 Why?
Fibroblasts1201842960.020 Why?
Flow Cytometry1201862600.020 Why?
Niacinamide120094230.020 Why?
Cholinesterase Inhibitors120082300.020 Why?
Diabetes Mellitus1200247180.020 Why?
DNA Damage1201624150.020 Why?
Promoter Regions, Genetic2201261280.020 Why?
Mice, Transgenic1201999320.020 Why?
Genome, Human1201943670.020 Why?
Models, Immunological120085290.020 Why?
Rabbits1201254400.020 Why?
Protein Transport1201120910.020 Why?
Drug Delivery Systems1201722570.020 Why?
RNA, Messenger12021135190.020 Why?
Tacrolimus120087130.020 Why?
Milk Proteins120051790.020 Why?
Down-Regulation1201232120.020 Why?
Green Fluorescent Proteins1201022390.020 Why?
Two-Hybrid System Techniques120054920.020 Why?
Cell Death1201017610.020 Why?
Gene Expression1201780710.020 Why?
Vanadates12003790.020 Why?
Cell Cycle1201230510.020 Why?
Disease Progression12020128590.020 Why?
Benzamides1200912130.020 Why?
Endoplasmic Reticulum1201011580.020 Why?
Hepatocyte Nuclear Factor 112002310.020 Why?
POU Domain Factors12002340.020 Why?
Pancreatic Neoplasms1202046570.020 Why?
Disease Models, Animal22015181330.020 Why?
Molecular Chaperones120087390.020 Why?
Melanoma1202053870.020 Why?
Hepatocyte Nuclear Factor 1-beta12002910.020 Why?
Internet1201630860.020 Why?
Hepatocyte Nuclear Factor 1-alpha120021360.020 Why?
X-Ray Diffraction120024330.020 Why?
Cells, Cultured22009205830.020 Why?
Precipitin Tests120039130.020 Why?
Microscopy, Fluorescence1201029330.020 Why?
Neurons2201591790.020 Why?
Epithelial Cells1201537110.020 Why?
Janus Kinase 2120054910.010 Why?
Software1201642400.010 Why?
Gene Expression Profiling1201894450.010 Why?
Stress, Physiological1201014860.010 Why?
Vascular Endothelial Growth Factor A1201234660.010 Why?
Blotting, Northern1200316830.010 Why?
Codon120026070.010 Why?
Calcium1201356010.010 Why?
DNA, Complementary1200321540.010 Why?
Genotype12014128410.010 Why?
SH2 Domain-Containing Protein Tyrosine Phosphatases11998480.010 Why?
Tissue Distribution1200324520.010 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 6119981320.010 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 11119982600.010 Why?
Oxidative Stress1200831500.010 Why?
Peptide Mapping119962840.010 Why?
Prognosis12017280270.010 Why?
Protein-Tyrosine Kinases1200524020.010 Why?
MAP Kinase Signaling System1200316000.010 Why?
Stem Cells1200835290.010 Why?
Brain Ischemia1200830550.010 Why?
Trans-Activators1200531040.010 Why?
Time Factors22010418420.010 Why?
Transfection1200363670.010 Why?
Young Adult12020540780.010 Why?
Mutation, Missense1200224720.010 Why?
Adolescent12020827960.010 Why?
Male220203439170.010 Why?
T-Lymphocytes12008100950.010 Why?
Aged120201569370.010 Why?
Kidney1200366220.010 Why?
Liver1200374750.010 Why?
Adult120202062950.000 Why?
Middle Aged120202107470.000 Why?
Dhe-Paganon's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (472)
Explore
_
Co-Authors (85)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.