Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Philipp Lirk, M.D., Ph.D.

Concepts (537)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Anesthetics, Local3720249975.170 Why?
Anesthesia, Conduction1520242623.740 Why?
Nerve Block1720247063.190 Why?
Pain, Postoperative22202417403.060 Why?
Lidocaine1420245383.030 Why?
Diabetic Neuropathies820184052.560 Why?
Anesthesia, Epidural720212332.480 Why?
Analgesia820224612.040 Why?
Anesthesia, Spinal620232802.020 Why?
Analgesia, Epidural1020193321.890 Why?
Sciatic Nerve1120246171.570 Why?
Amides520164491.370 Why?
Anesthesiology7202211201.300 Why?
Perioperative Period420202501.240 Why?
Anesthesia7202215951.230 Why?
Norepinephrine220218971.210 Why?
Phantom Limb32023981.190 Why?
Ganglia, Spinal1020125261.170 Why?
Anesthesia, Obstetrical420172331.130 Why?
Peripheral Nerves720244791.060 Why?
Anesthesia, Local420232771.020 Why?
Bupivacaine1020194120.970 Why?
Analgesics11202410700.860 Why?
Ligamentum Flavum42016200.840 Why?
Amputees12023910.820 Why?
p38 Mitogen-Activated Protein Kinases520126870.810 Why?
Analgesics, Opioid11202438080.810 Why?
Colorectal Surgery120241220.790 Why?
Neurotoxicity Syndromes220163010.750 Why?
Abscess320216060.740 Why?
Perioperative Care4202410360.720 Why?
Hematoma, Epidural, Spinal22018370.710 Why?
Neurons, Afferent620084980.690 Why?
Post-Dural Puncture Headache12021530.690 Why?
Analgesics, Non-Narcotic520193700.690 Why?
Hematoma320217670.680 Why?
Amitriptyline420071120.660 Why?
Analgesia, Obstetrical220181690.660 Why?
Acetaminophen620245550.650 Why?
Meningitis120202170.630 Why?
Atracurium52005510.620 Why?
Pain Measurement12202135510.610 Why?
Injections220188310.540 Why?
Peripheral Nervous System Diseases220137100.520 Why?
Pressure2201811540.510 Why?
Thoracic Vertebrae320055970.500 Why?
Exhalation320051810.490 Why?
Risk Management120185580.490 Why?
Laparoscopy2202420360.470 Why?
Anesthesia Recovery Period120151550.470 Why?
Dose-Response Relationship, Drug182018107660.450 Why?
Arthroplasty, Replacement, Hip2202114130.450 Why?
Evidence-Based Medicine3202436880.450 Why?
Intraoperative Complications1202011660.440 Why?
Orthopedics120228980.440 Why?
Serotonin Antagonists120131450.430 Why?
Ondansetron12013950.420 Why?
Orthopedic Procedures2202212650.420 Why?
Membrane Potentials5200810900.420 Why?
Laryngeal Masks520041030.410 Why?
Cadaver9202413580.410 Why?
Diabetes Mellitus, Experimental1201811190.400 Why?
Monitoring, Intraoperative120189420.400 Why?
Arthroplasty, Replacement, Knee1202213930.380 Why?
Data Interpretation, Statistical1202126910.380 Why?
Rats182018237410.370 Why?
DNA Methylation3201543990.360 Why?
Humans11320247615960.360 Why?
Fentanyl420174340.350 Why?
Neuromuscular Nondepolarizing Agents420051430.350 Why?
Butadienes320081070.340 Why?
Mass Spectrometry8200821920.330 Why?
Anesthesia, General4201711740.330 Why?
Thrombocytopenia1201711820.320 Why?
Lower Extremity4202412020.310 Why?
Netherlands5202022210.300 Why?
Axons2200716740.300 Why?
Anesthetics, Inhalation620035740.300 Why?
Organic Chemicals220082100.300 Why?
Nervous System Diseases1201816670.300 Why?
Breath Tests520082990.290 Why?
Stress, Physiological1201514030.290 Why?
Imidazoles3201211800.290 Why?
Cervical Vertebrae220049800.290 Why?
Acetonitriles22005540.290 Why?
Neurons5201294630.280 Why?
Abdomen3201911280.280 Why?
Pneumonia, Aspiration220041460.280 Why?
Postoperative Complications52020156330.280 Why?
Pentanes2200350.270 Why?
Hemiterpenes22003180.270 Why?
Hypotension120128790.270 Why?
Isoquinolines220053520.260 Why?
Sulfones220054480.250 Why?
Ketamine320185190.250 Why?
Diclofenac22017680.250 Why?
Neoplasm Metastasis2201649150.250 Why?
Subclavian Vein12005570.250 Why?
Electric Stimulation3201717360.250 Why?
Cesarean Section2201213980.240 Why?
Superior Cervical Ganglion12004330.240 Why?
Acrylates22004780.240 Why?
Hydrofluoric Acid12004130.240 Why?
Epigenesis, Genetic2201538010.240 Why?
Xerophthalmia12004120.230 Why?
Enzyme Inhibitors4201237130.230 Why?
Pantothenic Acid12004170.230 Why?
Neuromuscular Blocking Agents220041290.230 Why?
Adjuvants, Anesthesia22015580.230 Why?
Prader-Willi Syndrome12004780.220 Why?
Wound Healing1201528050.220 Why?
Nitric Oxide Synthase320059080.220 Why?
Cyclooxygenase Inhibitors120053610.220 Why?
Oral Surgical Procedures120051660.220 Why?
Rats, Zucker220141310.220 Why?
Procaine22014600.220 Why?
Caspases320168790.220 Why?
Anti-Inflammatory Agents, Non-Steroidal6201922730.220 Why?
Burns, Chemical120041230.220 Why?
Lactones120053170.210 Why?
Mitogen-Activated Protein Kinases1200812460.210 Why?
Cell Survival5201457910.210 Why?
Analgesia, Patient-Controlled320171160.210 Why?
Halothane120032000.210 Why?
Cellulose120031180.210 Why?
Thigh120242410.210 Why?
Dwarfism120031380.210 Why?
Limb Deformities, Congenital120031360.210 Why?
Musculoskeletal Diseases220195980.200 Why?
Biomedical Research1201834290.200 Why?
Radial Artery120041870.200 Why?
Upper Extremity220246580.200 Why?
Inflammation42015107740.200 Why?
Delirium1201316680.190 Why?
Pyridines3201228750.190 Why?
Wounds, Penetrating120043130.190 Why?
Action Potentials4201518340.190 Why?
Electrocardiography1201463770.190 Why?
Rats, Sprague-Dawley10201281810.180 Why?
Female4720243927050.180 Why?
Animals2420181684750.180 Why?
Spinal Nerves32012910.180 Why?
Delphi Technique120248460.180 Why?
Vitamin A120046130.180 Why?
Digestive System Surgical Procedures220165720.180 Why?
Blood Patch, Epidural12021570.180 Why?
Calcium3200857220.180 Why?
Catheterization, Peripheral120043430.180 Why?
Terrorism120032110.170 Why?
Catheterization, Central Venous120055260.170 Why?
Apoptosis6201294900.170 Why?
Receptors, N-Methyl-D-Aspartate320158950.170 Why?
Critical Care2202126970.170 Why?
Mastectomy2201918220.170 Why?
Eye120047120.170 Why?
Wounds and Injuries3201724920.170 Why?
Prisoners120033140.170 Why?
Cognition Disorders1201339800.170 Why?
Needles220154510.160 Why?
Methyl Ethers520031960.160 Why?
Air Pollutants, Occupational420024070.160 Why?
Brachial Plexus120211670.160 Why?
Mass Screening3200854290.160 Why?
Efficiency120224760.160 Why?
Cells, Cultured72012189660.160 Why?
Respiratory Rate120191760.150 Why?
Vital Signs120191440.150 Why?
Breast Neoplasms32019210190.150 Why?
Arm Injuries120191560.150 Why?
Pregnancy72021298900.150 Why?
Graft Occlusion, Vascular120215370.150 Why?
Leg Injuries120191790.150 Why?
Infusions, Intravenous2202022170.150 Why?
Saphenous Vein220215160.150 Why?
Lumbar Vertebrae2200518790.150 Why?
DNA, Neoplasm2201417450.150 Why?
Male4320243608460.140 Why?
Sodium Channels320083390.140 Why?
Face1200310260.140 Why?
Terminology as Topic1202415300.140 Why?
Mepivacaine1201680.140 Why?
Time Factors112019399690.140 Why?
Neoplasms72021221730.140 Why?
Enzyme Activation3200835970.140 Why?
Pain7202150730.140 Why?
Sufentanil12016420.140 Why?
Intubation, Intratracheal5200413330.130 Why?
Spine1200311180.130 Why?
Treatment Refusal120194290.130 Why?
Necrosis1202016110.130 Why?
Abnormalities, Multiple1200314230.130 Why?
Operating Rooms420037890.130 Why?
Insurance Claim Review120207410.130 Why?
JNK Mitogen-Activated Protein Kinases220084410.130 Why?
Abdominal Wall120171660.130 Why?
Catastrophization120193480.130 Why?
Consensus1202431240.120 Why?
Antidepressive Agents, Tricyclic220074320.120 Why?
Randomized Controlled Trials as Topic22024102120.120 Why?
Adult3020202212100.120 Why?
Platelet Count120177810.120 Why?
Lumbosacral Region120162930.120 Why?
Risk3201796100.120 Why?
Middle Aged2720202209210.110 Why?
Dexmedetomidine120183190.110 Why?
Receptor, Muscarinic M112013250.110 Why?
Torsades de Pointes12014780.110 Why?
Receptor, Muscarinic M312013370.110 Why?
Anesthetics, General120151510.110 Why?
Neuromuscular Agents120151470.110 Why?
Drug Synergism2201517570.110 Why?
Renal Dialysis1200317960.110 Why?
Catheterization1201914280.110 Why?
Chi-Square Distribution4201934150.110 Why?
Population Surveillance1200425980.110 Why?
Treatment Failure3202226430.110 Why?
Neopterin22003560.110 Why?
Diffusion of Innovation120187280.110 Why?
Aged, 80 and over122020589840.110 Why?
Electrophysiological Phenomena120143070.100 Why?
Azacitidine120143360.100 Why?
Ambulatory Surgical Procedures120174640.100 Why?
Feedback, Physiological120154760.100 Why?
Treatment Outcome122021646850.100 Why?
Decompression, Surgical120176070.100 Why?
Magnesium120158040.100 Why?
Protein Kinase Inhibitors1200856720.100 Why?
L-Lactate Dehydrogenase120124110.100 Why?
Musculoskeletal System120131880.090 Why?
Dexamethasone1201919480.090 Why?
Models, Animal2201521120.090 Why?
Ultrasonography2202159710.090 Why?
Hyperalgesia120155320.090 Why?
Cell Count2201218350.090 Why?
Forced Expiratory Flow Rates12010750.090 Why?
Hip Fractures120199880.090 Why?
Antimetabolites, Antineoplastic120146460.090 Why?
Smoking2200590530.090 Why?
Aged1820201693100.090 Why?
Double-Blind Method42017123410.090 Why?
Long QT Syndrome120144670.090 Why?
Cohort Studies52020414950.090 Why?
Guidelines as Topic1201613860.090 Why?
Ultrasonography, Interventional4202114960.090 Why?
Equipment Failure120125780.080 Why?
Behavior, Animal3201218780.080 Why?
Epidural Space220161220.080 Why?
Patient Positioning120123260.080 Why?
Vascular Resistance120129300.080 Why?
RNA, Neoplasm120127500.080 Why?
Guillain-Barre Syndrome120111270.080 Why?
Triage120169860.080 Why?
Pattern Recognition, Visual120158230.080 Why?
Forecasting1201829280.080 Why?
Cell Size220086240.080 Why?
Pilot Projects4201686330.080 Why?
Signal Transduction32018234470.080 Why?
Anthracenes12008830.080 Why?
Breast1201719670.080 Why?
Lumbosacral Plexus12008510.080 Why?
Obturator Nerve22023110.080 Why?
Edetic Acid120082760.070 Why?
Occupational Exposure3200318130.070 Why?
Sensory Receptor Cells120125130.070 Why?
Molecular Targeted Therapy1201928110.070 Why?
Psoas Muscles12008660.070 Why?
Retrospective Studies72021806470.070 Why?
Genes, Tumor Suppressor1201210620.070 Why?
Opioid-Related Disorders2201921640.070 Why?
Cytoprotection120082000.070 Why?
Nitric Oxide Synthase Type II320055170.070 Why?
Vital Capacity120109710.070 Why?
Endpoint Determination120105900.070 Why?
Cadmium120082140.070 Why?
Magnesium Sulfate12007730.070 Why?
Data Collection3200533220.070 Why?
Emergency Service, Hospital4201978790.070 Why?
Visual Cortex1201511080.070 Why?
Chelating Agents120083870.070 Why?
Skin1202044840.070 Why?
Glucose1201843470.070 Why?
Amino Acid Chloromethyl Ketones12006680.070 Why?
Lipoxygenase Inhibitors12006930.070 Why?
Tumor Cells, Cultured1201461310.070 Why?
Drug Administration Schedule2201248530.070 Why?
PC12 Cells120063170.070 Why?
Infusions, Parenteral220173970.070 Why?
Single-Blind Method1201015740.070 Why?
Europe1201334200.070 Why?
Enzyme Precursors120061700.070 Why?
Lipid Metabolism1201419020.070 Why?
Risk Assessment22020239960.060 Why?
Coloring Agents120085620.060 Why?
Health Care Surveys1201324260.060 Why?
Cerebral Hemorrhage, Traumatic12005200.060 Why?
Cytochromes c120061730.060 Why?
Hyperglycemia2201813760.060 Why?
Swine1201559150.060 Why?
Neurotoxins120062400.060 Why?
Extracellular Signal-Regulated MAP Kinases120086150.060 Why?
Electrophysiology1200812620.060 Why?
Respiratory Function Tests1201016820.060 Why?
Clinical Trials as Topic1202180020.060 Why?
Visual Perception1201313890.060 Why?
Arachidonic Acid120064270.060 Why?
Anesthesia, Inhalation220042200.060 Why?
Calcium Channel Blockers120086940.060 Why?
Mitochondrial Membranes120061760.060 Why?
Databases, Factual1202079680.060 Why?
HELLP Syndrome12004400.060 Why?
Education, Continuing120051140.060 Why?
Ointments12004580.060 Why?
Catheters220194270.060 Why?
Nitrates120052630.060 Why?
Motor Neuron Disease12004970.060 Why?
Preoperative Care2201722420.060 Why?
Blood Glucose2201863910.060 Why?
Caspase 3120067310.060 Why?
Anesthetics, Intravenous220043950.060 Why?
Diabetes Mellitus, Type 11201834150.060 Why?
Receptors, Estrogen1201222090.060 Why?
Androstanols12003450.060 Why?
Practice Guidelines as Topic1202173910.060 Why?
Trigeminal Ganglion120041900.060 Why?
Heart Septum120043010.060 Why?
Moscow1200360.060 Why?
Gastritis120051990.060 Why?
Body Weight1201446180.060 Why?
Colony Count, Microbial120043300.050 Why?
Punctures120043660.050 Why?
Intracranial Hypertension120051930.050 Why?
Nitriles120089710.050 Why?
Fascia120231400.050 Why?
Accidents, Occupational120042490.050 Why?
Prospective Studies52019544230.050 Why?
Statistics, Nonparametric2200528500.050 Why?
Aging3201487100.050 Why?
Helicobacter pylori120053770.050 Why?
Uremia120032010.050 Why?
Spinal Puncture120042820.050 Why?
Helicobacter Infections120053880.050 Why?
Cytosol120058880.050 Why?
Liver Function Tests120035230.050 Why?
Hernia, Inguinal120042200.050 Why?
Cross-Over Studies2200520790.050 Why?
Diabetes Mellitus, Type 222018121490.050 Why?
Drug Therapy, Combination3201763120.050 Why?
Nitric Oxide Synthase Type I120021740.050 Why?
Forearm120044270.050 Why?
Area Under Curve1200516380.050 Why?
Toluidines12001210.050 Why?
Kidney Function Tests120036790.050 Why?
Urologic Surgical Procedures120042980.050 Why?
Propofol220046030.050 Why?
Phenotype32008165920.050 Why?
Craniotomy120057410.050 Why?
Inhalation Exposure120034320.040 Why?
Polytetrafluoroethylene120212450.040 Why?
Postoperative Care2201714680.040 Why?
Disease Models, Animal22018182550.040 Why?
Fluid Therapy120045790.040 Why?
Neutrophils1201337670.040 Why?
Demography1200516480.040 Why?
Rhinoplasty120032380.040 Why?
Veins120047680.040 Why?
Vascular Grafting120211620.040 Why?
Nitric Oxide3200521360.040 Why?
Iceland120191840.040 Why?
MAP Kinase Signaling System1200614860.040 Why?
Hospital Administration120033530.040 Why?
Pregnancy Outcome1201029220.040 Why?
Infusions, Subcutaneous12019430.040 Why?
Young Adult62019592600.040 Why?
Functional Laterality1200522570.040 Why?
Nitric Oxide Synthase Type III120027050.040 Why?
Animals, Newborn1200426770.040 Why?
Hand120049030.040 Why?
Hydrogels120047200.040 Why?
Child, Preschool42004422320.040 Why?
Vascular Patency120219110.040 Why?
Observer Variation1200426060.040 Why?
Peritoneum120192250.040 Why?
Cell Line, Tumor22012169900.040 Why?
Syndrome1200332670.040 Why?
RNA, Messenger12012127940.030 Why?
Phosphorylation1200883210.030 Why?
Infusions, Intralesional1201630.030 Why?
Infant, Newborn22010262020.030 Why?
Cell Proliferation12012104510.030 Why?
Drug Dosage Calculations120161170.030 Why?
Tibial Nerve12016500.030 Why?
Peroneal Nerve12016760.030 Why?
Gene Expression Regulation, Neoplastic1201285540.030 Why?
Hyperlipidemias120017710.030 Why?
Polymers1200316160.030 Why?
Anatomy, Cross-Sectional120161410.030 Why?
Environmental Monitoring1200214600.030 Why?
Multiple Sclerosis1201132220.030 Why?
Staphylococcus aureus1200414570.030 Why?
Muscle, Smooth, Vascular1200214920.030 Why?
Oxidative Stress2200531130.030 Why?
Anaphylaxis120037570.030 Why?
Shock, Septic120027680.030 Why?
Knee Joint1202416760.030 Why?
Laparotomy120174570.030 Why?
Neural Conduction120164410.030 Why?
Sensory Thresholds120163770.030 Why?
Ion Channels1201910400.030 Why?
Pain Perception120161960.030 Why?
Administration, Topical120167040.030 Why?
Extracorporeal Membrane Oxygenation1200514620.030 Why?
Head and Neck Neoplasms1200828940.030 Why?
Amyotrophic Lateral Sclerosis1200414690.030 Why?
Models, Biological3200894690.030 Why?
Thoracic Surgical Procedures120173500.030 Why?
Carcinoma1200423300.030 Why?
Synaptic Transmission1201911730.030 Why?
Surgical Procedures, Operative1200419240.030 Why?
Respiration, Artificial1200426300.030 Why?
Mitochondria1200636240.030 Why?
Evoked Potentials, Motor120164640.030 Why?
Neurosurgical Procedures1200420720.030 Why?
Postoperative Period1201718140.030 Why?
Vascular Surgical Procedures1202114890.030 Why?
Carcinoma, Squamous Cell1200840240.030 Why?
United States12020723400.030 Why?
Patient Preference120199270.020 Why?
Models, Anatomic120166830.020 Why?
Cell Line22005156010.020 Why?
Morphine120166570.020 Why?
Endothelial Cells1200535490.020 Why?
Monitoring, Physiologic1201917790.020 Why?
Stereoisomerism120136140.020 Why?
Acute Disease2201772370.020 Why?
Superoxides120133870.020 Why?
Hypoglycemia120188830.020 Why?
Solubility1201310910.020 Why?
Cross-Sectional Studies22018261290.020 Why?
Clinical Protocols1201514400.020 Why?
Severity of Illness Index22019158430.020 Why?
Xenopus laevis120139630.020 Why?
Volatilization12008770.020 Why?
Oocytes1201311660.020 Why?
Photic Stimulation1201519870.020 Why?
Femoral Nerve12008420.020 Why?
Doxepin12007160.020 Why?
Imipramine12007980.020 Why?
Structure-Activity Relationship1201330760.020 Why?
Oximes120083030.020 Why?
Xerostomia12007940.020 Why?
Pancreatic Neoplasms1200453680.020 Why?
Heart Defects, Congenital1200346710.020 Why?
Chemotherapy, Adjuvant1201535140.020 Why?
Equipment Design2200435110.020 Why?
Sodium Channel Blockers120071730.020 Why?
Proprioception120071330.020 Why?
Hospitals1201938830.020 Why?
Hydrogen Cyanide1200540.020 Why?
Research Design2201561800.020 Why?
Axotomy12005710.020 Why?
Bradycardia120072990.020 Why?
Case-Control Studies22019221760.020 Why?
Recovery of Function1201529790.020 Why?
Follow-Up Studies22017391060.020 Why?
Injections, Intravenous1200713790.020 Why?
Cyclooxygenase 2 Inhibitors120073210.020 Why?
Ligation120054480.010 Why?
DNA Fragmentation120052370.010 Why?
Capsaicin120052310.010 Why?
Umbilical Veins120054260.010 Why?
Potassium1200813110.010 Why?
Antidotes120051380.010 Why?
Tomography, X-Ray Computed22005205680.010 Why?
Random Allocation1200823950.010 Why?
Recovery Room12003340.010 Why?
Internship and Residency1200458820.010 Why?
Dogs1200838390.010 Why?
Benzimidazoles120088580.010 Why?
Sleep Stages120076940.010 Why?
Patient Satisfaction1201534620.010 Why?
Air120031870.010 Why?
Ventilator Weaning120041640.010 Why?
Biotransformation120031660.010 Why?
Electric Impedance120077570.010 Why?
Operating Room Nursing12002250.010 Why?
Thoracic Injuries120052880.010 Why?
Imaging, Three-Dimensional1201640620.010 Why?
Elasticity120046550.010 Why?
Glutathione120055830.010 Why?
Age Factors12019183990.010 Why?
Length of Stay1201564260.010 Why?
Postanesthesia Nursing12001100.010 Why?
Hydroxymethylglutaryl CoA Reductases12001600.010 Why?
Gastrointestinal Tract120078330.010 Why?
Gene Expression Regulation, Enzymologic1200511710.010 Why?
Lung Injury120054220.010 Why?
Risk Factors22007742130.010 Why?
Tracheostomy120044260.010 Why?
Fluoroscopy120049470.010 Why?
Indoles1200818330.010 Why?
Disease Progression12017135100.010 Why?
Reproducibility of Results22008201000.010 Why?
Telephone120036270.010 Why?
Continuous Positive Airway Pressure120045750.010 Why?
Fatal Outcome1200418350.010 Why?
Brain Mapping1201566350.010 Why?
Cell Culture Techniques1200716680.010 Why?
Adolescent22019883260.010 Why?
Cerebral Infarction120049830.010 Why?
Image Processing, Computer-Assisted1201690010.010 Why?
Neoplasm Recurrence, Local1201792800.010 Why?
Otorhinolaryngologic Surgical Procedures120013240.010 Why?
Medical Staff, Hospital120026010.010 Why?
Positive-Pressure Respiration120026390.010 Why?
Magnetic Resonance Imaging22016364260.010 Why?
Isoflurane120013840.010 Why?
Enzyme-Linked Immunosorbent Assay1200538100.010 Why?
Accidental Falls1200510680.010 Why?
Motor Activity1200727150.010 Why?
Immunity, Cellular1200215600.010 Why?
Respiratory Insufficiency1200412300.010 Why?
Cell Membrane1200536870.010 Why?
Cell Division1200344650.010 Why?
Reference Values1200249200.010 Why?
Reoperation1200443030.010 Why?
Heart1200744040.010 Why?
Brain Injuries1200520540.010 Why?
Child12021801580.010 Why?
Cost-Benefit Analysis1200354930.010 Why?
Anticoagulants1200548120.010 Why?
Curriculum1200337430.010 Why?
Lung12005100020.000 Why?
Algorithms12007140330.000 Why?
Predictive Value of Tests12001152660.000 Why?
Cardiovascular Diseases12007155020.000 Why?
Infant12002361930.000 Why?
Brain12005271210.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.