Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Philipp Lirk, M.D., Ph.D.

Concepts (537)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Anesthetics, Local37202410045.130 Why?
Anesthesia, Conduction1520242633.710 Why?
Nerve Block1720247163.150 Why?
Pain, Postoperative22202417653.020 Why?
Lidocaine1420245462.980 Why?
Diabetic Neuropathies820184102.530 Why?
Anesthesia, Epidural720212322.470 Why?
Analgesia820224602.030 Why?
Anesthesia, Spinal620232822.010 Why?
Analgesia, Epidural1020193321.880 Why?
Sciatic Nerve1120246281.550 Why?
Amides520164521.360 Why?
Anesthesiology7202211371.290 Why?
Perioperative Period420202521.230 Why?
Anesthesia7202215961.220 Why?
Norepinephrine220219001.200 Why?
Phantom Limb320231061.180 Why?
Ganglia, Spinal1020125301.160 Why?
Anesthesia, Obstetrical420172351.120 Why?
Peripheral Nerves720244921.040 Why?
Anesthesia, Local420232791.020 Why?
Bupivacaine1020194130.970 Why?
Analgesics11202410720.850 Why?
Ligamentum Flavum42016200.840 Why?
Amputees120231000.810 Why?
Analgesics, Opioid11202438370.800 Why?
p38 Mitogen-Activated Protein Kinases520126920.800 Why?
Colorectal Surgery120241250.780 Why?
Neurotoxicity Syndromes220163020.740 Why?
Abscess320216060.730 Why?
Perioperative Care4202410450.710 Why?
Hematoma, Epidural, Spinal22018370.710 Why?
Neurons, Afferent620084980.690 Why?
Post-Dural Puncture Headache12021530.690 Why?
Analgesics, Non-Narcotic520193710.680 Why?
Hematoma320217680.670 Why?
Amitriptyline420071120.660 Why?
Analgesia, Obstetrical220181690.650 Why?
Acetaminophen620245560.640 Why?
Meningitis120202190.630 Why?
Atracurium52005510.620 Why?
Pain Measurement12202135850.600 Why?
Injections220188410.530 Why?
Peripheral Nervous System Diseases220137160.520 Why?
Pressure2201811720.500 Why?
Thoracic Vertebrae320056140.500 Why?
Exhalation320051850.480 Why?
Risk Management120185580.480 Why?
Laparoscopy2202420550.460 Why?
Anesthesia Recovery Period120151550.460 Why?
Dose-Response Relationship, Drug182018107780.450 Why?
Arthroplasty, Replacement, Hip2202114210.450 Why?
Evidence-Based Medicine3202437090.440 Why?
Intraoperative Complications1202011760.440 Why?
Orthopedics120229060.440 Why?
Serotonin Antagonists120131470.430 Why?
Ondansetron12013950.420 Why?
Orthopedic Procedures2202212800.420 Why?
Membrane Potentials5200810900.420 Why?
Cadaver9202413660.400 Why?
Diabetes Mellitus, Experimental1201811240.400 Why?
Laryngeal Masks520041180.400 Why?
Monitoring, Intraoperative120189500.390 Why?
Arthroplasty, Replacement, Knee1202214050.380 Why?
Data Interpretation, Statistical1202127140.370 Why?
Rats182018238470.370 Why?
DNA Methylation3201544320.360 Why?
Humans11320247688870.350 Why?
Neuromuscular Nondepolarizing Agents420051450.350 Why?
Fentanyl420174500.340 Why?
Butadienes320081070.340 Why?
Mass Spectrometry8200822040.330 Why?
Anesthesia, General4201711890.320 Why?
Thrombocytopenia1201711810.320 Why?
Lower Extremity4202412170.310 Why?
Netherlands5202022770.300 Why?
Anesthetics, Inhalation620035730.300 Why?
Axons2200716780.300 Why?
Organic Chemicals220082110.300 Why?
Nervous System Diseases1201816650.300 Why?
Breath Tests520083000.290 Why?
Imidazoles3201211690.290 Why?
Stress, Physiological1201514100.290 Why?
Cervical Vertebrae220049820.290 Why?
Acetonitriles22005550.280 Why?
Neurons5201295240.280 Why?
Pneumonia, Aspiration220041450.270 Why?
Abdomen3201911370.270 Why?
Postoperative Complications52020158890.270 Why?
Pentanes2200350.270 Why?
Hemiterpenes22003180.270 Why?
Hypotension120128880.260 Why?
Isoquinolines220053540.260 Why?
Sulfones220054480.250 Why?
Ketamine320185270.250 Why?
Diclofenac22017690.250 Why?
Neoplasm Metastasis2201649260.250 Why?
Subclavian Vein12005570.250 Why?
Electric Stimulation3201717430.240 Why?
Cesarean Section2201214170.240 Why?
Superior Cervical Ganglion12004330.240 Why?
Acrylates22004750.240 Why?
Hydrofluoric Acid12004130.240 Why?
Epigenesis, Genetic2201538360.230 Why?
Enzyme Inhibitors4201237240.230 Why?
Xerophthalmia12004120.230 Why?
Pantothenic Acid12004170.230 Why?
Neuromuscular Blocking Agents220041320.230 Why?
Adjuvants, Anesthesia22015580.220 Why?
Wound Healing1201528150.220 Why?
Prader-Willi Syndrome12004790.220 Why?
Nitric Oxide Synthase320059110.220 Why?
Cyclooxygenase Inhibitors120053610.220 Why?
Oral Surgical Procedures120051720.220 Why?
Rats, Zucker220141310.220 Why?
Procaine22014600.220 Why?
Caspases320168810.220 Why?
Anti-Inflammatory Agents, Non-Steroidal6201922770.210 Why?
Burns, Chemical120041230.210 Why?
Lactones120053160.210 Why?
Mitogen-Activated Protein Kinases1200812460.210 Why?
Cell Survival5201457940.210 Why?
Analgesia, Patient-Controlled320171170.210 Why?
Cellulose120031170.210 Why?
Halothane120032000.210 Why?
Thigh120242390.210 Why?
Dwarfism120031370.200 Why?
Limb Deformities, Congenital120031360.200 Why?
Musculoskeletal Diseases220196010.200 Why?
Biomedical Research1201834630.200 Why?
Radial Artery120041880.200 Why?
Upper Extremity220246830.200 Why?
Inflammation42015108690.190 Why?
Delirium1201316960.190 Why?
Pyridines3201228960.190 Why?
Wounds, Penetrating120043160.190 Why?
Action Potentials4201518380.190 Why?
Electrocardiography1201464130.190 Why?
Rats, Sprague-Dawley10201282000.180 Why?
Animals2420181694080.180 Why?
Female4720243974640.180 Why?
Spinal Nerves32012920.180 Why?
Vitamin A120046110.180 Why?
Digestive System Surgical Procedures220165840.180 Why?
Blood Patch, Epidural12021570.180 Why?
Delphi Technique120248900.180 Why?
Calcium3200857920.180 Why?
Catheterization, Peripheral120043470.170 Why?
Terrorism120032110.170 Why?
Apoptosis6201295280.170 Why?
Critical Care2202127150.170 Why?
Catheterization, Central Venous120055360.170 Why?
Eye120047120.170 Why?
Receptors, N-Methyl-D-Aspartate320159050.170 Why?
Mastectomy2201918500.170 Why?
Wounds and Injuries3201725170.170 Why?
Cognition Disorders1201339850.170 Why?
Prisoners120033160.160 Why?
Methyl Ethers520031960.160 Why?
Needles220154610.160 Why?
Air Pollutants, Occupational420024060.160 Why?
Mass Screening3200854550.160 Why?
Efficiency120224800.160 Why?
Brachial Plexus120211730.160 Why?
Cells, Cultured72012190230.160 Why?
Respiratory Rate120191800.150 Why?
Vital Signs120191440.150 Why?
Arm Injuries120191560.150 Why?
Breast Neoplasms32019211870.150 Why?
Graft Occlusion, Vascular120215380.150 Why?
Leg Injuries120191800.150 Why?
Pregnancy72021301750.150 Why?
Infusions, Intravenous2202022310.150 Why?
Saphenous Vein220215190.150 Why?
Lumbar Vertebrae2200518890.150 Why?
DNA, Neoplasm2201417480.150 Why?
Sodium Channels320083410.140 Why?
Male4320243652490.140 Why?
Face1200310310.140 Why?
Terminology as Topic1202415410.140 Why?
Mepivacaine1201680.140 Why?
Time Factors112019402660.140 Why?
Neoplasms72021223900.140 Why?
Enzyme Activation3200835880.140 Why?
Pain7202151000.140 Why?
Sufentanil12016420.140 Why?
Spine1200311410.130 Why?
Treatment Refusal120194320.130 Why?
Intubation, Intratracheal5200413590.130 Why?
Necrosis1202016210.130 Why?
Abnormalities, Multiple1200314230.130 Why?
Operating Rooms420037930.130 Why?
Insurance Claim Review120207460.130 Why?
JNK Mitogen-Activated Protein Kinases220084400.130 Why?
Abdominal Wall120171660.130 Why?
Catastrophization120193520.120 Why?
Consensus1202432140.120 Why?
Antidepressive Agents, Tricyclic220074330.120 Why?
Platelet Count120177870.120 Why?
Lumbosacral Region120162940.120 Why?
Randomized Controlled Trials as Topic22024103970.120 Why?
Adult3020202238180.120 Why?
Risk3201796210.120 Why?
Dexmedetomidine120183200.110 Why?
Middle Aged2720202237400.110 Why?
Receptor, Muscarinic M112013250.110 Why?
Torsades de Pointes12014780.110 Why?
Receptor, Muscarinic M312013370.110 Why?
Anesthetics, General120151520.110 Why?
Neuromuscular Agents120151480.110 Why?
Renal Dialysis1200317890.110 Why?
Drug Synergism2201517620.110 Why?
Catheterization1201914310.110 Why?
Population Surveillance1200425970.110 Why?
Chi-Square Distribution4201934380.110 Why?
Treatment Failure3202226630.110 Why?
Diffusion of Innovation120187320.110 Why?
Neopterin22003580.110 Why?
Aged, 80 and over122020597380.100 Why?
Electrophysiological Phenomena120143100.100 Why?
Azacitidine120143360.100 Why?
Ambulatory Surgical Procedures120174720.100 Why?
Feedback, Physiological120154810.100 Why?
Treatment Outcome122021654850.100 Why?
Decompression, Surgical120176100.100 Why?
Magnesium120158160.100 Why?
Protein Kinase Inhibitors1200857070.100 Why?
L-Lactate Dehydrogenase120124120.090 Why?
Musculoskeletal System120131880.090 Why?
Dexamethasone1201919650.090 Why?
Models, Animal2201521230.090 Why?
Hyperalgesia120155270.090 Why?
Cell Count2201218330.090 Why?
Ultrasonography2202160010.090 Why?
Forced Expiratory Flow Rates12010750.090 Why?
Hip Fractures120199960.090 Why?
Antimetabolites, Antineoplastic120146470.090 Why?
Smoking2200590940.090 Why?
Aged1820201717900.090 Why?
Double-Blind Method42017124690.090 Why?
Long QT Syndrome120144720.090 Why?
Cohort Studies52020418000.090 Why?
Guidelines as Topic1201613980.080 Why?
Behavior, Animal3201218790.080 Why?
Ultrasonography, Interventional4202115240.080 Why?
Equipment Failure120125850.080 Why?
Epidural Space220161230.080 Why?
Patient Positioning120123320.080 Why?
RNA, Neoplasm120127510.080 Why?
Vascular Resistance120129390.080 Why?
Guillain-Barre Syndrome120111270.080 Why?
Triage120169970.080 Why?
Pattern Recognition, Visual120158260.080 Why?
Cell Size220086260.080 Why?
Forecasting1201829460.080 Why?
Pilot Projects4201687420.080 Why?
Signal Transduction32018236520.080 Why?
Anthracenes12008830.080 Why?
Breast1201719760.080 Why?
Obturator Nerve22023110.070 Why?
Lumbosacral Plexus12008540.070 Why?
Occupational Exposure3200318070.070 Why?
Edetic Acid120082780.070 Why?
Sensory Receptor Cells120125080.070 Why?
Molecular Targeted Therapy1201928300.070 Why?
Psoas Muscles12008660.070 Why?
Genes, Tumor Suppressor1201210640.070 Why?
Cytoprotection120082000.070 Why?
Retrospective Studies72021818920.070 Why?
Opioid-Related Disorders2201921890.070 Why?
Nitric Oxide Synthase Type II320055150.070 Why?
Endpoint Determination120105940.070 Why?
Vital Capacity120109970.070 Why?
Data Collection3200533220.070 Why?
Cadmium120082170.070 Why?
Magnesium Sulfate12007730.070 Why?
Visual Cortex1201511120.070 Why?
Emergency Service, Hospital4201979560.070 Why?
Chelating Agents120083850.070 Why?
Skin1202045070.070 Why?
Glucose1201843520.070 Why?
Amino Acid Chloromethyl Ketones12006680.070 Why?
Lipoxygenase Inhibitors12006930.070 Why?
Tumor Cells, Cultured1201461310.070 Why?
Drug Administration Schedule2201248620.070 Why?
PC12 Cells120063170.070 Why?
Infusions, Parenteral220173970.070 Why?
Single-Blind Method1201015850.070 Why?
Europe1201334410.070 Why?
Enzyme Precursors120061660.070 Why?
Lipid Metabolism1201419040.060 Why?
Coloring Agents120085640.060 Why?
Risk Assessment22020243300.060 Why?
Health Care Surveys1201324370.060 Why?
Cerebral Hemorrhage, Traumatic12005200.060 Why?
Cytochromes c120061730.060 Why?
Hyperglycemia2201813890.060 Why?
Neurotoxins120062410.060 Why?
Swine1201559980.060 Why?
Extracellular Signal-Regulated MAP Kinases120086150.060 Why?
Electrophysiology1200812660.060 Why?
Respiratory Function Tests1201016950.060 Why?
Clinical Trials as Topic1202180550.060 Why?
Arachidonic Acid120064290.060 Why?
Visual Perception1201314070.060 Why?
Anesthesia, Inhalation220042200.060 Why?
Calcium Channel Blockers120086910.060 Why?
Mitochondrial Membranes120061850.060 Why?
Databases, Factual1202080950.060 Why?
HELLP Syndrome12004400.060 Why?
Education, Continuing120051150.060 Why?
Catheters220194270.060 Why?
Ointments12004580.060 Why?
Nitrates120052600.060 Why?
Motor Neuron Disease12004980.060 Why?
Preoperative Care2201722580.060 Why?
Caspase 3120067310.060 Why?
Blood Glucose2201864340.060 Why?
Anesthetics, Intravenous220043970.060 Why?
Diabetes Mellitus, Type 11201834470.060 Why?
Receptors, Estrogen1201222520.060 Why?
Androstanols12003470.060 Why?
Trigeminal Ganglion120041860.060 Why?
Practice Guidelines as Topic1202174600.060 Why?
Gastritis120051990.050 Why?
Moscow1200360.050 Why?
Body Weight1201446280.050 Why?
Heart Septum120043040.050 Why?
Colony Count, Microbial120043280.050 Why?
Punctures120043720.050 Why?
Intracranial Hypertension120051930.050 Why?
Nitriles120089900.050 Why?
Fascia120231430.050 Why?
Accidents, Occupational120042510.050 Why?
Prospective Studies52019549500.050 Why?
Statistics, Nonparametric2200528620.050 Why?
Aging3201487650.050 Why?
Helicobacter pylori120053800.050 Why?
Cytosol120058860.050 Why?
Uremia120032020.050 Why?
Liver Function Tests120035260.050 Why?
Spinal Puncture120042860.050 Why?
Helicobacter Infections120053900.050 Why?
Hernia, Inguinal120042250.050 Why?
Diabetes Mellitus, Type 222018122520.050 Why?
Drug Therapy, Combination3201763200.050 Why?
Cross-Over Studies2200521080.050 Why?
Nitric Oxide Synthase Type I120021750.050 Why?
Forearm120044280.050 Why?
Area Under Curve1200516450.050 Why?
Toluidines12001210.050 Why?
Kidney Function Tests120036840.050 Why?
Urologic Surgical Procedures120042990.050 Why?
Propofol220046080.050 Why?
Phenotype32008167350.040 Why?
Craniotomy120057470.040 Why?
Inhalation Exposure120034310.040 Why?
Polytetrafluoroethylene120212450.040 Why?
Postoperative Care2201714810.040 Why?
Disease Models, Animal22018183660.040 Why?
Fluid Therapy120045870.040 Why?
Demography1200516430.040 Why?
Neutrophils1201337850.040 Why?
Rhinoplasty120032410.040 Why?
Veins120047690.040 Why?
Vascular Grafting120211630.040 Why?
Nitric Oxide3200521490.040 Why?
Iceland120191830.040 Why?
MAP Kinase Signaling System1200614940.040 Why?
Hospital Administration120033530.040 Why?
Infusions, Subcutaneous12019430.040 Why?
Pregnancy Outcome1201029570.040 Why?
Functional Laterality1200522690.040 Why?
Nitric Oxide Synthase Type III120027060.040 Why?
Young Adult62019601100.040 Why?
Animals, Newborn1200426950.040 Why?
Hand120049130.040 Why?
Child, Preschool42004426840.040 Why?
Vascular Patency120219170.040 Why?
Hydrogels120047450.040 Why?
Observer Variation1200426230.040 Why?
Peritoneum120192310.040 Why?
Cell Line, Tumor22012171740.030 Why?
Syndrome1200332740.030 Why?
RNA, Messenger12012128090.030 Why?
Phosphorylation1200883170.030 Why?
Infusions, Intralesional1201630.030 Why?
Infant, Newborn22010263940.030 Why?
Cell Proliferation12012104860.030 Why?
Drug Dosage Calculations120161170.030 Why?
Tibial Nerve12016550.030 Why?
Peroneal Nerve12016800.030 Why?
Hyperlipidemias120017730.030 Why?
Gene Expression Regulation, Neoplastic1201286640.030 Why?
Polymers1200316320.030 Why?
Staphylococcus aureus1200414300.030 Why?
Anatomy, Cross-Sectional120161390.030 Why?
Environmental Monitoring1200214660.030 Why?
Multiple Sclerosis1201132500.030 Why?
Muscle, Smooth, Vascular1200214930.030 Why?
Anaphylaxis120037580.030 Why?
Oxidative Stress2200531380.030 Why?
Shock, Septic120027740.030 Why?
Knee Joint1202416850.030 Why?
Laparotomy120174590.030 Why?
Neural Conduction120164430.030 Why?
Sensory Thresholds120163770.030 Why?
Pain Perception120161980.030 Why?
Ion Channels1201910440.030 Why?
Administration, Topical120167040.030 Why?
Extracorporeal Membrane Oxygenation1200514830.030 Why?
Head and Neck Neoplasms1200829310.030 Why?
Amyotrophic Lateral Sclerosis1200414730.030 Why?
Models, Biological3200894990.030 Why?
Thoracic Surgical Procedures120173500.030 Why?
Carcinoma1200423400.030 Why?
Synaptic Transmission1201911770.030 Why?
Surgical Procedures, Operative1200419410.030 Why?
Evoked Potentials, Motor120164650.030 Why?
Mitochondria1200636830.030 Why?
Neurosurgical Procedures1200421100.030 Why?
Respiration, Artificial1200427240.030 Why?
Postoperative Period1201718300.030 Why?
Vascular Surgical Procedures1202115150.030 Why?
Carcinoma, Squamous Cell1200840640.030 Why?
United States12020731800.020 Why?
Models, Anatomic120166830.020 Why?
Patient Preference120199470.020 Why?
Cell Line22005156030.020 Why?
Morphine120166580.020 Why?
Stereoisomerism120136120.020 Why?
Monitoring, Physiologic1201917960.020 Why?
Endothelial Cells1200535910.020 Why?
Acute Disease2201772450.020 Why?
Superoxides120133890.020 Why?
Hypoglycemia120188950.020 Why?
Solubility1201310870.020 Why?
Cross-Sectional Studies22018263840.020 Why?
Clinical Protocols1201514450.020 Why?
Xenopus laevis120139660.020 Why?
Severity of Illness Index22019159550.020 Why?
Volatilization12008760.020 Why?
Oocytes1201311720.020 Why?
Photic Stimulation1201520030.020 Why?
Femoral Nerve12008420.020 Why?
Doxepin12007160.020 Why?
Structure-Activity Relationship1201330560.020 Why?
Imipramine12007980.020 Why?
Oximes120083030.020 Why?
Xerostomia12007940.020 Why?
Pancreatic Neoplasms1200454430.020 Why?
Heart Defects, Congenital1200347110.020 Why?
Chemotherapy, Adjuvant1201535540.020 Why?
Equipment Design2200435290.020 Why?
Sodium Channel Blockers120071730.020 Why?
Hospitals1201939030.020 Why?
Hydrogen Cyanide1200540.020 Why?
Proprioception120071340.020 Why?
Research Design2201562130.020 Why?
Axotomy12005710.020 Why?
Bradycardia120073050.020 Why?
Case-Control Studies22019222940.020 Why?
Recovery of Function1201529900.020 Why?
Follow-Up Studies22017393940.020 Why?
Injections, Intravenous1200713790.010 Why?
Cyclooxygenase 2 Inhibitors120073210.010 Why?
Ligation120054460.010 Why?
DNA Fragmentation120052400.010 Why?
Capsaicin120052350.010 Why?
Umbilical Veins120054250.010 Why?
Potassium1200813190.010 Why?
Antidotes120051380.010 Why?
Tomography, X-Ray Computed22005207760.010 Why?
Random Allocation1200823960.010 Why?
Recovery Room12003340.010 Why?
Internship and Residency1200459560.010 Why?
Dogs1200838450.010 Why?
Benzimidazoles120088640.010 Why?
Air120031870.010 Why?
Patient Satisfaction1201534890.010 Why?
Sleep Stages120077060.010 Why?
Ventilator Weaning120041700.010 Why?
Biotransformation120031660.010 Why?
Operating Room Nursing12002250.010 Why?
Thoracic Injuries120052880.010 Why?
Electric Impedance120077950.010 Why?
Imaging, Three-Dimensional1201640770.010 Why?
Elasticity120046570.010 Why?
Glutathione120055890.010 Why?
Age Factors12019184540.010 Why?
Length of Stay1201565250.010 Why?
Postanesthesia Nursing12001100.010 Why?
Hydroxymethylglutaryl CoA Reductases12001640.010 Why?
Gastrointestinal Tract120078390.010 Why?
Gene Expression Regulation, Enzymologic1200511690.010 Why?
Lung Injury120054330.010 Why?
Risk Factors22007749710.010 Why?
Tracheostomy120044300.010 Why?
Fluoroscopy120049470.010 Why?
Indoles1200818360.010 Why?
Disease Progression12017136770.010 Why?
Reproducibility of Results22008202440.010 Why?
Telephone120036300.010 Why?
Fatal Outcome1200418360.010 Why?
Cell Culture Techniques1200716670.010 Why?
Continuous Positive Airway Pressure120045800.010 Why?
Brain Mapping1201567400.010 Why?
Cerebral Infarction120049750.010 Why?
Adolescent22019892470.010 Why?
Image Processing, Computer-Assisted1201690810.010 Why?
Neoplasm Recurrence, Local1201794420.010 Why?
Otorhinolaryngologic Surgical Procedures120013260.010 Why?
Medical Staff, Hospital120026030.010 Why?
Magnetic Resonance Imaging22016368610.010 Why?
Isoflurane120013840.010 Why?
Positive-Pressure Respiration120027130.010 Why?
Enzyme-Linked Immunosorbent Assay1200538140.010 Why?
Accidental Falls1200510800.010 Why?
Motor Activity1200727220.010 Why?
Immunity, Cellular1200215600.010 Why?
Cell Membrane1200536590.010 Why?
Respiratory Insufficiency1200412410.010 Why?
Cell Division1200344780.010 Why?
Reference Values1200249410.010 Why?
Reoperation1200443420.010 Why?
Heart1200744480.010 Why?
Brain Injuries1200520580.010 Why?
Child12021809690.010 Why?
Cost-Benefit Analysis1200355440.010 Why?
Anticoagulants1200548500.010 Why?
Curriculum1200337820.010 Why?
Lung12005100970.000 Why?
Algorithms12007141990.000 Why?
Predictive Value of Tests12001154710.000 Why?
Cardiovascular Diseases12007156620.000 Why?
Infant12002365410.000 Why?
Brain12005274760.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.